Tag: M.W=150-200

Miranda, Bruna M. published the artcileA galactose-rich heteropolysaccharide extracted from “”jaboticaba”” (Plinia cauliflora) peels, Category: alcohols-buliding-blocks, the main research area is jaboticaba Plinia cauliflora galactose; Arabinogalactan; GC/MS chromatography; Relative viscosity; Rheology.

The objective of this work was to extract, identify and characterize a galactose-rich heteropolysaccharide (GH) from “”jaboticaba”” peel. The best conditions to extract the GH according to a 23 full-factorial expremental design were 90°C/30 min/pH 1.0, resulting in a 32.32% yield using lyophilized sample. The chem. structure analyzed by GC/MS and NMR spectra (HSQC/HSQC-TOCSY) showed that the main chain of GH consists of a (1→4) galactoside branched at carbon 3, containing galactose (67.21%), glucose (15.78%), arabinose (9.78%), rhamnose (2.26%) and traces of esterified and non-esterified uronic acids. Rheol studies revealed that GH suspensions behave as a Newtonian fluid, with calculated mol. mass of 1.48 x 105 Da. The abstract viscosity of 1% (w/v) aq suspension of GH decreased from 25 mPa s to 10 mPa s in NaCl and 7 mPa s in CaCl2, indicating the polyelectrolyte character of GH.

Carbohydrate Polymers published new progress about Behavior. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Shaikh, Kashif Mohd published the artcileMolecular profiling of an oleaginous trebouxiophycean alga Parachlorella kessleri subjected to nutrient deprivation for enhanced biofuel production, Application of rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, the main research area is Parachlorella biofuel lipid metabolism photosynthesis; Biofuels; Metabolomics; Microalgae; Nutrient deprivation; Parachlorella kessleri.

Background: Decreasing fossil fuels and its impact on global warming have led to an increasing demand for its replacement by sustainable renewable biofuels. Microalgae may offer a potential feedstock for renewable biofuels capable of converting atm. CO2 to substantial biomass and valuable biofuels, which is of great importance for the food and energy industries. Parachlorella kessleri, a marine unicellular green alga belonging to class Trebouxiophyceae, accumulates large amount of lipids under nutrient-deprived conditions. The present study aims to understand the metabolic imprints in order to elucidate the physiol. mechanisms of lipid accumulations in this microalga under nutrient deprivation. Results: Mol. profiles were obtained using gas chromatog.-mass spectrometry (GC-MS) of P. kessleri subjected to nutrient deprivation. Relative quantities of more than 60 metabolites were systematically compared in all the three starvation conditions. Our results demonstrate that in lipid metabolism, the quantities of neutral lipids increased significantly followed by the decrease in other metabolites involved in photosynthesis, and nitrogen assimilation. Nitrogen starvation seems to trigger the triacylglycerol (TAG) accumulation rapidly, while the microalga seems to tolerate phosphorous limitation, hence increasing both biomass and lipid content. The metabolomic and lipidomic profiles have identified a few common metabolites such as citric acid and 2-ketoglutaric acid which play significant role in diverting flux towards acetyl-CoA leading to accumulation of neutral lipids, whereas other mols. such as trehalose involve in cell growth regulation, when subjected to nutrient deprivation. Conclusions: Understanding the entire system through qual. (untargeted) metabolome approach in P. kessleri has led to identification of relevant metabolites involved in the biosynthesis and degradation of precursor mols. that may have potential for biofuel production, aiming towards the vision of tomorrow’s bioenergy needs.

Biotechnology for Biofuels published new progress about Biofuels. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Application of rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Shapira, Anna published the artcileTandem Mass Spectrometric Quantification of 93 Terpenoids in Cannabis Using Static Headspace Injections, Recommanded Product: rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, the main research area is Cannabis terpenoid GC quadrupole tandem MS.

The therapeutic effect of Cannabis largely depends on the content of its pharmacol. active secondary metabolites, mainly phytocannabinoids, flavonoids, and terpenoids. Recent studies suggest there are therapeutic effects of specific terpenoids as well as synergistic effects with other active compounds in the plant. Although Cannabis contains an overwhelming milieu of terpenoids, only a limited number are currently reported and used for metabolic anal. of Cannabis chemovars. In this study, we report the development and validation of a method for simultaneous quantification of 93 terpenoids in Cannabis air-dried inflorescences and extracts This method employs the full evaporation technique via a static headspace sampler, followed by gas chromatog.-mass spectrometry (SHS-GC/MS/MS). In the validation process, spiked terpenoids were quantified with acceptable repeatability, reproducibility, sensitivity, and accuracy. Three medical Cannabis chemovars were used to study the effect of sample preparation and extraction methods on terpenoid profiles. This method was further applied for studying the terpenoid profiles of 16 different chemovars acquired at different dates. Our results demonstrate that sample preparation methods may significantly impact the chem. fingerprint compared to the nontreated Cannabis. This emphasizes the importance of performing SHS extraction in order to study the natural terpenoid contents of chemovars. We also concluded that most inflorescences expressed relatively unique terpenoid profiles for the most pronounced terpenoids, even when sampled at different dates, although absolute concentrations may vary due to aging. The suggested method offers an ideal tool for terpenoid profiling of Cannabis and sets the scene for more comprehensive works in the future.

Analytical Chemistry (Washington, DC, United States) published new progress about Cannabis. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Recommanded Product: rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yang, Zhirui published the artcileNetwork pharmacology-based dissection of the underlying mechanisms of dyspnoea induced by zedoary turmeric oil, Formula: C10H18O, the main research area is network pharmacol dyspnoea zedoary turmeric oil; binding affinity; dyspnoea; haemoglobin; network pharmacology; zedoary turmeric oil.

Zedoary turmeric oil (ZTO) has been widely used in clinic. However, the unpleasant induced dyspnoea inevitably impedes its clin. application. Thus, it is urgent to elucidate the mechanism underlying the ZTO-induced dyspnoea. In this study, network pharmacol. was firstly performed to search the clue of ZTO-induced dyspnoea. The key target genes of ZTO-induced dyspnoea were analyzed using GO enrichment anal. and KEGG pathway anal. GO anal. suggested that haem binding could be a key mol. function involved in ZTO-induced dyspnoea. Hence, the Hb (Hb) was focused for its oxygen-carrying capacity with haem as its critical component binding to the oxygen. UV-visible absorption spectrum indicated that the ZTO injection (ZTOI) perturbed the Soret band of Hb, suggesting an interaction between ZTO and Hb. GC-MS anal. revealed that β-elemene, germacrone, curdione and furanodiene were main components of ZTOI. Mol. docking was used to illustrate the high affinity between representative sesquiterpenes and Hb, which was finally confirmed by surface plasmon resonance, suggesting their potential roles in dyspnoea by ZTO. Following a network pharmacol.-driven strategy, our study revealed an intervened Hb-based mechanism underlying the ZTO-induced dyspnoea, providing a reference for elucidating mechanism underlying adverse drug reactions of herbal medicines in clinic.

Basic & Clinical Pharmacology & Toxicology published new progress about Affinity. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Formula: C10H18O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yeh, Ping-Yuan published the artcileChanges undergone by citronella-oil fractions on storage, Product Details of C10H20O2, the main research area is .

During 43-month storage in the dark at room temperature some of the distilled citronella oil fractions had completely changed. The changed citronellal fraction consisted of H2O 1, isopulegol 20, menthoglycol (?) 10, citronellic acid 12, and citronellylidenecitronellal and higher condensation products 57%. The terpene fractions and the terpene alc. fractions also changed to the oxidation, condensation, and polymerization products. A pure citronellal fraction stood for 5 years almost unchanged.

Taiwan Kexue published new progress about Alcohols. 42822-86-6 belongs to class alcohols-buliding-blocks, name is 2-(2-Hydroxypropan-2-yl)-5-methylcyclohexanol, and the molecular formula is C10H20O2, Product Details of C10H20O2.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Safaeian Laein, Sara published the artcileEvaluation of antibacterial and antioxidant activities of essential oil of lime (Citrus aurantifolia) pomace powder, Computed Properties of 124-76-5, the main research area is Citrus aurantifolia pomace essential oil antioxidant antibacterial activity.

This study aimed to determine the chem. compounds, antioxidant and antimicrobial activities of Essential Oil (EO) derived from lime pomace. Gas chromatog./mass spectrometry (GC-MS) was used to determine the major components of the obtained EO. The antioxidant activities of this EO were determined by radical scavenging activity (DPPH) and the Ferric Reducing Antioxidant Power (FRAP) test. For antimicrobial activity, the disk diffusion method was used and the Min. Inhibitory Concentrations (MIC) and the Min. Bactericidal Concentration (MBC) were studied against common foodborne pathogens including; Staphylococcus aureus, Bacillus cereus, Listeria monocytogenes, Escherichia coli, Salmonella typhimurium, and Pseudomonas aeruginosa. The result showed that the Gram-pos. bacteria were more susceptible than gram-neg. bacteria. The result shows that lime pomace powder with IC50 83.061 mg/mL has a high antioxidant capacity and also, the chem. anal. of the EO showed that the EO contained a complex mixture of several components and the main constituents were D-limonene (28.86%), a- terpinene (15.65%) and D-terpinene (12.72%) resp.

Iranian Journal of Chemistry & Chemical Engineering published new progress about Analysis. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Computed Properties of 124-76-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhang, Xue published the artcilePlasma galactose-deficient immunoglobulin A1 and loss of kidney function in patients with immunoglobulin A vasculitis nephritis, Computed Properties of 59-23-4, the main research area is human plasma galactose IgA vasculitis nephritis kidney function; IgA nephropathy; IgA vasculitis nephritis; galactose-deficient IgA1; kidney disease progression.

IgA (IgA) vasculitis nephritis (IgAV-N) is the most common secondary IgA nephropathy (IgAN). Many studies have demonstrated that galactose-deficient IgA1 (Gd-IgA1) in the IgA1 hinge region is associated with the development and also progression of primary IgAN. In this study, we aimed to evaluate the roles of Gd-IgA1 in kidney disease progression in a large Chinese cohort of IgAV-N patients. This cohort study enrolled 112 patients with IgAVN, 15 patients with IgA vasculitis (IgAV) without kidney involvement and 108 patients with IgAN. Plasma IgA1 and Gd- IgA1 levels at kidney biopsy were measured by ELISA. The primary endpoint was a 30% decline in estimated glomerular filtration rate or end-stage renal disease or death. The levels of Gd-IgA1 in IgAV-N and IgAN patients were higher than in healthy controls (mean±SD, 302.86±54.93 U/mL vs. 303.16±59.43 U/mL vs. 281.30±43.74 U/mL, resp.; P = 0.047), as well as compared with those with IgAV without kidney involvement (272.65±53.14 U/mL; P = 0.036). After adjusting clin. data, higher levels of Gd-IgA1 were found to be independently associated with a greater risk for kidney failure [hazard ratio (HR)=1.703 per 1 SD, 95% confidence interval (CI) 1.233-2.352; P = 0.001]. Compared with the first Gd-IgA1 quartile group (as reference), the fourth Gd-IgA1 quartile group retained a predictive value for poor renal outcome (HR = 3.740, 95% CI 1.204-11.619; P = 0.023). These data indicate that Gd-IgA1 levels were similarly elevated in adult patients with IgAN and those with IgAV-N. Moreover, increased Gd-IgA1 levels were associated with both the development and progression of IgAV-N, as observed in IgAN.

Nephrology, Dialysis, Transplantation published new progress about Analysis. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Computed Properties of 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zeng, Xiaotong published the artcileEffects of deproteinization methods on primary structure and antioxidant activity of Ganoderma lucidum polysaccharides, Category: alcohols-buliding-blocks, the main research area is Ganoderma polysaccharide antioxidant activity primary structure deproteinization method; Antioxidant activities; Deproteinization; Ganoderma lucidum polysaccharides; Primary structure.

Ganoderma lucidum polysaccharides (GLP) as one of water-soluble polysaccharides has attracted much attention because of its bioactivities, especially antioxidant activity. Deproteinization is an essential step in the purification process of polysaccharides. In this study, three classic deproteinization methods, including neutral protease method, TCA precipitation and CaCl2 salting out, were evaluated for crude GLP processing. The methods had ability to remove proteins (71.50-87.36%), and meanwhile polysaccharide loss (8.35-11.39%) was observed Structure anal. indicated that these deproteinization methods had no significant effect (p > 0.05) on mol. weight of polysaccharides, but led to varying degrees of glycoside bond losses (1.14-64.05%). Moreover, the antioxidant activities of deproteinized polysaccharides were measured in vitro by hydroxyl radical, reducing power, 2, 2-diphenyl-1-picryl-hydrazyl (DPPH) free radical and ferric-reducing antioxidant power tests. Purified GLP by enzymolysis maintained the strongest antioxidants activities with the retention rate of over 47.40%, and its deproteinization efficiency and polysaccharide loss ratio were 74.03% and 11.39% resp. In view of relatively high purity and antioxidant activity, enzymolysis was a suitable deproteinization method for GLP production

International Journal of Biological Macromolecules published new progress about Angelica. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Lin, Shifan published the artcileStudy on the Effect of Mentha x piperita L. Essential Oil on Electroencephalography upon Stimulation with Different Visual Effects, Category: alcohols-buliding-blocks, the main research area is Mentha piperita essential oil electroencephalog stimulation visual effect; colour; electroencephalograph; inhalation; peppermint essential oil.

Essential oils have long been used to fight infections and treat various diseases. Peppermint (Mentha x piperita L.) is an herbal medicine that has been widely used in daily life since ancient times, and it has a wide range of applications in food, cosmetics, and medicine. Mint oil is refreshing because of its cool and comfortable smell; therefore, it is often used in ethnopharmacol. studies. The present study investigated the effects of peppermint essential oil in electroencephalog. activity response to various visual stimuli. The electroencephalog. changes of participants during peppermint essential oil inhalation under white, red, and blue color stimulations were recorded. A rapid Fourier transform anal. was used to examine the electroencephalograph power spectra of the various microstates induced by inhaling the oils. Peppermint essential oil had various effects on the brain when subjected to different visual stimuli. Alpha waves increased in the prefrontal area in the white-sniffing group, which facilitated learning and thinking. In the blue-sniffing group, the changes were less pronounced than those in the red group, and the increased alpha wave activity in the occipital area was more controlled, indicating that the participants’ visual function increased in this state. Based on EEG investigations, this is the first study to indicate that vision influences the effects of peppermint essential oils. Hence, the results of this study support the use of essential oils in a broader context to serve as a resource for future studies on the effects of different types of essential oils.

Molecules published new progress about Ayurveda. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Padra, Medea published the artcileHelicobacter suis infection alters glycosylation and decreases the pathogen growth inhibiting effect and binding avidity of gastric mucins, SDS of cas: 59-23-4, the main research area is Helicobacter suis infection glycosylation gastric mucin.

Helicobacter suis is the most prevalent non-Helicobacter pylori Helicobacter species in the human stomach and is associated with chronic gastritis, peptic ulcer disease, and gastric mucosa-associated lymphoid tissue (MALT) lymphoma. H. suis colonizes the gastric mucosa of 60-95% of pigs at slaughter age, and is associated with chronic gastritis, decreased weight gain, and ulcers. Here, we show that exptl. H. suis infection changes the mucin composition and glycosylation, decreasing the amount of H. suis-binding glycan structures in the pig gastric mucus niche. Similarly, the H. suis-binding ability of mucins from H. pylori-infected humans is lower than that of noninfected individuals. Furthermore, the H. suis growth-inhibiting effect of mucins from both noninfected humans and pigs is replaced by a growth-enhancing effect by mucins from infected individuals/pigs. Thus, Helicobacter spp. infections impair the mucus barrier by decreasing the H. suis-binding ability of the mucins and by decreasing the antiprolific activity that mucins can have on H. suis. Inhibition of these mucus-based defenses creates a more stable and inhabitable niche for H. suis. This is likely of importance for long-term colonization and outcome of infection, and reversing these impairments may have therapeutic benefits.

Mucosal Immunology published new progress about Gastritis. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, SDS of cas: 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts