Tag: M.W=150-200

Zhang, Tao published the artcilePurification, chemical analysis and antioxidative activity of polysaccharides from pH-modified citrus pectin after dialyzation, HPLC of Formula: 59-23-4, the main research area is modified citrus pectin polysaccharide purification chem analysis antioxidative activity.

Oxidative stress is a major risk factor implicated in the pathogenesis of many human diseases ranged from inflammation to cancer. Modified citrus pectin (MCP) is a com. available dietary supplement produced from citrus pectin. However, the antioxidative activity of MCP is currently unknown. In this study, MCP was fractionated by a combination of DEAE-cellulose and Sephadex G-75 chromatogs. into one neutral fraction (MCPN) and four acidic fractions (MCP02a, MCP02b, MCP04a, and MCP04b). Among these fractions, MCP02b and MCP04a exhibited good DPPH·-scavenging effect with a concentration-dependent manner. Structural anal. results showed that MCP02b mainly contained the HG domain as well as some RG-I domains with β-(1 → 4)-galactan side chains and 4-O-Me-β-GlcA attached to the nonreducing terminals of the side chains. These findings could extend the applications of MCP as an antioxidant agent for functional foods or food additives.

LWT–Food Science and Technology published new progress about Citrus. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, HPLC of Formula: 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ono, Atsushi published the artcileValidation of the (Q)SAR combination approach for mutagenicity prediction of flavor chemicals, Quality Control of 42822-86-6, the main research area is flavor chem mutagenicity quant structure activity relationship.

Most exposure levels of flavor in food are considered to be extremely low. If at all, genotoxic properties should be taken into account in safety evaluations. We have recently established a (quant.) structure-activity relationship, (Q)SAR, combination system, which is composed of three individual models of mutagenicity prediction for industrial chems. A decision on mutagenicity is defined as the combination of predictive results from the three models. To validate the utility of our (Q)SAR system for flavor evaluation, we assessed 367 flavor chems. that had been evaluated mainly by JECFA and for which Ames test results were available. When two or more models gave a pos. evaluation, the sensitivity was low (19.4%). In contrast, when one or more models gave a pos. evaluation, the sensitivity increased to 47.2%. The contribution of this increased sensitivity was mainly due to the result of the prediction by Derek for Windows, which is a knowledge-based model. Structural anal. of false negatives indicated some common sub-structures. The approach of improving sub-structural alerts could effectively contribute to increasing the predictability of the mutagenicity of flavors, because many flavors possess categorically similar functional sub-structures or are composed of a series of derivatives

Food and Chemical Toxicology published new progress about Flavor. 42822-86-6 belongs to class alcohols-buliding-blocks, name is 2-(2-Hydroxypropan-2-yl)-5-methylcyclohexanol, and the molecular formula is C10H20O2, Quality Control of 42822-86-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Dhull, Sanju Bala published the artcileFunctional, thermal and rheological behavior of fenugreek (Trigonella foenum-graecum L.) gums from different cultivars: A comparative study, Category: alcohols-buliding-blocks, the main research area is Trigonella gum thermal rheol behavior; FTIR, rheology; Fenugreek gum; Shear thinning; Thermal properties.

Fenugreek gum (FG) was isolated from six different Indian fenugreek cultivars and studied for their functional, structural, thermal and rheol. attributes. The highest yield (13.5%) was observed for cultivar RMT-365. All galactomannans depicted good water and oil holding capacities ranging from 2009 ± 5.5 to 2099.9 ± 2.5% and 523.5 ± 3.5 to 553.0 ± 2.0%, resp. DSC thermograms of FG revealed the presence of one endothermic and one exothermic peak. For endothermic transition of gums from different cultivars, enthalpy change (Δ Ha) ranged from 234.2 to 351.8 J/g while for exothermic transition, Δ Ha values ranged from 72.0 to 102.1 J/g, much lower as compared with endothermic peak. The effect of variable shear rate on viscosity of 1% FG solutions showed their shear thinning behaviors for all the cultivars, whereby the viscosity decreased with increasing shear rate. Frequency sweep tests indicated typical viscoelastic fluid behavior for all the gum solutions Increase in the magnitude of G’ and G” of FG solutions was observed with an increase in frequency. A detailed understanding of different chem., functional and thermal properties of FG could surely enlarge the radius of its application and eventually aid in its utilization in different food, pharma and cosmetic products.

International Journal of Biological Macromolecules published new progress about Density. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ciotlaus, Irina published the artcileCromathographic profile of volatiles of multifloral and unifloral honey collected by Apis mellifera from Transilvania, Romania, HPLC of Formula: 124-76-5, the main research area is chromatog Apis honey Transilvania.

Chromatog. profile of volatiles organic compounds (VOCs) from several varieties of multifloral and unifloral honey produced in Transylvania, Romania, was analyzed in order to determine the differences between them. VOCs collected using solid phase microextraction (SPME) technique were analyzed by gas-chromatog. coupled with mass-spectrometry (GC-MS). The fiber used was Carboxen / PDMS (polydimethylsiloxane) 75μm. By qual. anal., a number of 98 volatiles in unifloral honey and 52 volatiles in multifloral honey were identified. The differences regarding volatile compounds of multifloral honey were observed to be between varieties from different areas of Transylvania (mountain, plain, hill and urban area) while in the case of unifloral assortments (rapeseed, acacia, sunflower and linden) differences were observed at specific compounds Compounds identified in our samples were grouped into main classes of substances: hydrocarbons, alcs., aldehydes, ketones, organic acids and their esters, furan and pyran derivatives and terpenes.

Revista de Chimie (Bucharest, Romania) published new progress about Acacia. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, HPLC of Formula: 124-76-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wang, Qing published the artcileStructural characterization of a novel polysaccharide from Pleurotus citrinopileatus and its antitumor activity on H22 tumor-bearing mice, Formula: C6H12O6, the main research area is polysaccharide antitumor agent arabinose liver cancer inflammation anemia; Antitumor activity; Pleurotus citrinopileatus; Polysaccharide; Structural characterization.

In this research, a novel polysaccharide (PCP) was extracted from Pleurotus citrinopileatus and purified by Sephadex G-150 gel column, and its antitumor activity was investigated using the model H22 tumor-bearing mice. PCP was found to be composed of arabinose, galactose, glucose, xylose, mannose and glucuronic acid in a proportion of 0.66: 14.59: 10.77: 1: 0.69: 0.23 with average mol. weight of 7.30 x 105 Da. Further anal. suggested that PCP was a pyranose with α-type and β-type glycosidic residues. The antitumor assays in vivo indicated that PCP could effectively suppress H22 solid tumor growth, protect immune organs and improve inflammation and anemia. Besides, Annexin V-FITC/PI double staining and JC-1 staining demonstrated that PCP could induce apoptosis of H22 hepatoma cells. The PI staining assay revealed that PCP induced H22 hepatoma cells apoptosis by arresting cell cycle in S phase. These results suggest that the polysaccharide from Pleurotus citrinopileatus possesses potential value in the treatment of liver cancer.

International Journal of Biological Macromolecules published new progress about Anemia. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Formula: C6H12O6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Eriksen, Peter Lykke published the artcileNon-alcoholic fatty liver disease causes dissociated changes in metabolic liver functions, Synthetic Route of 59-23-4, the main research area is metabolism non alc fatty liver disease; Aminopyrine; Hepatic elimination; Indocyanine green; Liver function tests; Non-alcoholic steatohepatitis; Urea cycle.

Background: Non-alc. fatty liver disease (NAFLD) is a major health concern affecting 25% of the world’s population. It is generally held that a fatty liver does not influence liver function, but quant. measurements of metabolic liver functions have not been systematically performed. We aimed to study selected hepatocellular metabolic functions in patients with different stages of NAFLD. Methods: Twenty-five non-diabetic, biopsy-proven NAFLD patients [12 with simple steatosis; 13 with non-alc. steatohepatitis (NASH)] and ten healthy controls were included in a cross-sectional study. Hepatocyte cytosolic function was assessed by the galactose elimination capacity (GEC), mitochondrial-cytosolic metabolic capacity by the functional hepatic nitrogen clearance (FHNC), microsomal function by the aminopyrine breath test, and excretory liver function by indocyanine green (ICG) elimination. Results: GEC was 20% higher in NAFLD than in controls [3.15 mmol/min (2.9-3.41) vs. 2.62 (2.32-2.93); P = 0.02]. FHNC was 30% lower in NAFLD [23.3 L/h (18.7-28.9) vs. 33.1 (28.9-37.9); P = 0.04], more so in simple steatosis [19.1 L/h (13.9-26.2); P = 0.003] and non-significantly in NASH [27.9 L/h (20.6-37.8); P = 0.19]. Aminopyrine metabolism was 25% lower in simple steatosis [8.9% (7.0-10.7)] and 50% lower in NASH [6.0% (4.5-7.5)] than in controls [11.9% (9.3-12.8)] (P < 0.001). ICG elimination was intact. Conclusions: The hepatocellular metabolic functions were altered in a manner that was dissociated both by different effects on different liver functions and by different effects of different stages of NAFLD. Thus, NAFLD has widespread consequences for metabolic liver function, even in simple steatosis. Clinics and Research in Hepatology and Gastroenterology published new progress about Cytosol. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Synthetic Route of 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Roman-Carrasco, Patricia published the artcileOnly α-Gal bound to lipids, but not to proteins, is transported across enterocytes as an IgE-reactive molecule that can induce effector cell activation, Computed Properties of 59-23-4, the main research area is galactose protein lipid intestinal epithelial cell allergenic activity; chylomicron; delayed allergic reaction; glycolipid; glycoprotein; red meat allergy; α-Gal.

To better understand the delayed onset of allergic symptoms and investigate whether protein-bound or lipid-bound α-Gal causes these symptoms, we analyzed the capacity of α-Gal conjugated proteins and lipids to cross a monolayer of intestinal cells. Extracts of proteins and lipids from beef were prepared, subjected to in vitro digestions, and added to Caco-2 cells grown on permeable supports. The presence of α-Gal in the basolateral medium was investigated by immunoblotting, thin-layer chromatog. with immunostaining and ELISA, and its allergenic activity was analyzed in a basophil activation test. After addition of beef proteins to the apical side of Caco-2 cells, α-Gal containing peptides were not detected in the basolateral medium. Those peptides that crossed the Caco-2 monolayer did not activate basophils from an α-Gal allergic patient. Instead, when Caco-2 cells were incubated with lipids extracted from beef, α-Gal was detected in the basolateral medium. Furthermore, these α-Gal lipids were able to activate the basophils of an α-Gal allergic patient in a dose-dependent manner. Only α-Gal bound to lipids, but not to proteins, is able to cross the intestinal monolayer and trigger an allergic reaction. This suggests that the slower digestion and absorption of lipids might be responsible for the unusual delayed allergic reactions in α-Gal allergic patients and identifies glycolipids as potential allergenic mols.

Allergy (Oxford, United Kingdom) published new progress about Allergy. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Computed Properties of 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Hui, Heping published the artcileStructural characterization, antioxidant and antibacterial activities of two heteropolysaccharides purified from the bulbs of Lilium davidii var. unicolor Cotton, Recommanded Product: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, the main research area is Lilium bulb heteropolysaccharide antioxidant antibacterial; Antioxidant and antibacterial activity; Heteropolysaccharides; Lilium davidii var. unicolor Cotton; Structural characterization.

Two heteropolysaccharides, BHP-1 and BHP-2, were separated and purified from the edible bulbs of Lilium davidii var. unicolor Cotton by anion-exchange and gel-permeation chromatog. The primary structural characteristics of BHP-1 and BHP-2 were investigated by Congo red test, X-ray diffractometry (XRD) anal., IR, GC and NMR. The results showed that the weight-average mol. weight (MW) and number-average mol. weight (Mn) of BHP-1 and BHP-2 were nearly 1.93 × 105 g/moL, 8.86 × 104 g/moL and 3.52 × 104 g/moL, 2.95 × 104 g/moL, resp. Glucose and mannose comprised BHP-1 in a relative molar ratio of 5.9:2.0, and BHP-2 was consisted of glucose, galactose, mannose and arabinose with approx. molar ratios of 8.3:1.5:1.0:1.1. Their backbone mainly contained α-(1 → 4)-linked D-glucopyranosyl. In addition, the C-6 of the glucose and C-2 of mannose residue of BHP-1 and BHP-2 were substituted. The two polysaccharides were semi-crystalline substance with multi-branching structure and triple helix conformation. Bioassays showed that BHP-1 and BHP-2 had effective antioxidant activities evaluated by DPPH, scavenging superoxide radical and OH radical in a dose-dependent manner. The two heteropolysaccharides also displayed distinct and selective antibacterial activity against B. cereus, P. putida, M. luteus and K. pneumonia with inhibition zones of 13 mm, 16 mm, 17 mm, 23 mm and 12 mm, 17 mm, 19 mm, 20 mm, resp. These findings provided a reference for potential applications of the polysaccharides from L. davidii as natural antioxidants and antibacterial agents in food and pharmaceuticals.

International Journal of Biological Macromolecules published new progress about Anomers. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Recommanded Product: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Vorobyova, Viktoria published the artcileInhibition of mild steel corrosion in sodium chloride solution by apricot waste extract obtained from different solvent systems, Related Products of alcohols-buliding-blocks, the main research area is mild steel apricot waste corrosion morphol.

Purpose: This paper aims to investigate influence of extraction solvent on the efficacy of apricot pomace extract (APE) as a sustainable corrosion inhibitor for mild steel in sodium chloride solution Design/methodol./approach: The chem. profiles of the extracts were analyzed using gas chromatog.-mass spectrometry. Total phenolic, total flavonoid content and antioxidant properties of the extracts were determined Besides, gravimetric, potentiodynamic polarization and at. force microscopy were used to study the corrosion inhibition. The effect of immersion period on inhibition efficiency was evaluated. The reaction mechanism of the inhibitor was also discussed. Findings: Corrosion inhibition decreasing is in the following order: solution of 2-propanol/ethanol apricot pomace (E/PAPE) extract > ethanol (EAPE) > 2-propanol (PAPE). The gravimetric, polarization measurements and surface anal. revealed that the growth of inhibitory properties is prolonged, and corrosion rate reduction after 40-48 h of exposure was studied. Practical implications: APEs play an important role in the corrosion inhibition of mild steel in sodium chloride solution Moreover, its application is potentially possible in industries. Social implications: The results contribute to the integrated valorization of food waste. Originality/value: The different compositions of the conversion/oxidation products of organic substances in solution were studied. The formation of polymerized flavanol-aldehyde adducts and oxidized quinone compounds or tautomers structures because of extract transformation in water causes main corrosion reduction in 40-48 h.

Pigment & Resin Technology published new progress about Apricot. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Related Products of alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Vorobyova, Viktoria published the artcileApricot cake extract as corrosion inhibitor of steel: chemical composition and anti-corrosion properties, Recommanded Product: rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, the main research area is steel apricot cake extract corrosion inhibitor anticorrosion electrochem property.

The protection performance of self-assembled layers (SALs) formed by apricot cake extract (ACE) on the surface of steel has been studied. Characterization of the apricot cake extract was carried out using the gas chromatog.-mass spectrometry anal. The anti-corrosion effect of the self-assembled layers was determined by weight loss experiments, SEM and electrochem. methods. It was revealed that the protection ability of the SALs is determined by the time of film formation on the steel surface. The maximal corrosion inhibition efficiency (about 93%) was obtained after 48 h process of film formation in the vapor phase of the apricot cake extract The results of the polarization test revealed that the ACE acted as a mixed type inhibitor and retarded both anodic and cathodic reactions rates. The results of the electrochem. anal. revealed that the ACE modified steel showed better corrosion protection in conditions of periodic condensation of moisture.

Chemistry Journal of Moldova published new progress about Apricot. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Recommanded Product: rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts