Tag: M.W=150-200

Lyu, Shuxia published the artcileEffect of rare earth elements on vitamin C fermentation by mixed cultures, Formula: C6H10O7, the publication is International Journal of Agriculture and Biology (2014), 16(6), 1135-1140, database is CAplus.

In recent years, the research on rare earth metals has expanded to the field of microbiol. In China, the production of Vitamin C is through mixed culture fermentation, which transforms L-sorbose to 2-keto-L-gulonic acid (2-KGA), the precursor of Vitamin C. In this study we compared the yields of 2-KGA by an acid-producing strain of Ketogulonigenium vulgare that was co-cultured with different companion bacterial strains in the presence of four light rare earth elements, lanthanum, cerium, neodymium, and samarium at selected concentrations We found that all of the tested rare earth elements had a promoting effect on 2-KGA production at concentration up to 5 mM. At or above 10 mM, the yield of 2-KGA was reduced. When cultured sep. with 5 mM of given rare earth elements, the growth of two companion bacterial strains (Bacillus megaterium 25-B and B. subtilis A9) were both significantly reduced, while that of the K. vulgare strain was enhanced.

International Journal of Agriculture and Biology published new progress about 526-98-7. 526-98-7 belongs to alcohols-buliding-blocks, auxiliary class Sugar Units,Other Sugar Units, name is (3S,4R,5S)-3,4,5,6-Tetrahydroxy-2-oxohexanoic acid, and the molecular formula is C6H10O7, Formula: C6H10O7.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Gong, Xiao-li published the artcileEffects of Bacillus megaterium 2980’s spore formation on 2 KGA production of Gluconobacter oxydans, Safety of (3S,4R,5S)-3,4,5,6-Tetrahydroxy-2-oxohexanoic acid, the publication is Gongye Weishengwu (2013), 43(6), 49-53, database is CAplus.

In order to determine the relationship between the spore formation of Bacillus megaterium 2980 (B, m 2980, called companion bacterium) and Gluconobacter oxydans (G. o, called acid-producing strain) in vitamin C two-step fermentation, the effects of the culture supernatant, the cytosol and the mixed component solution of companion bacterium which cultured for 12 h (not forming spores) and 36 h (forming spores) on the growth of G. o and its synthesizing ability of 2-keto-L-gulonic acid (2-KGA) were studied through the anal. of B. m 2980 growth characteristics. The results showed that when the B. m 2980 spores did not form, the culture supernatant, the cytosol and mixed component solution had low effects on the growth of acid-producing strain and its 2-KGA production The cytosol of B. m 2980 promoted the growth and 2 KGA production of G. o greater than that of the culture supernatant. After the spore formation of B. m 2980, the culture supernatant and mixed component solution of B. m 2980 affected growth and 2-KGA production of G. o significantly.

Gongye Weishengwu published new progress about 526-98-7. 526-98-7 belongs to alcohols-buliding-blocks, auxiliary class Sugar Units,Other Sugar Units, name is (3S,4R,5S)-3,4,5,6-Tetrahydroxy-2-oxohexanoic acid, and the molecular formula is C6H10O7, Safety of (3S,4R,5S)-3,4,5,6-Tetrahydroxy-2-oxohexanoic acid.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Shivarkar, Anandkumar B. published the artcileTandem Synthesis of β-Amino Alcohols from Aniline, Dialkyl Carbonate, and Ethylene Glycol, Recommanded Product: 2-(Benzyl(methyl)amino)ethanol, the publication is Industrial & Engineering Chemistry Research (2008), 47(8), 2484-2494, database is CAplus.

An efficient tandem route for selective synthesis of β-amino alcs. from anilines, dialkyl carbonate and ethylene glycol in the presence of recyclable Na-Y zeolite was demonstrated. Transesterification of dialkyl carbonate by ethylene glycol produce ethylene carbonate which further reacts with aniline to give β-amino alcs. in a single step. This reaction system was studied under high-pressure and pot reaction condition. Various process parametric effects were studied for the reaction of aniline, dialkyl carbonate, and ethylene glycol. A maximum 51% yield of mono-β-amino alc., i.e., N-phenylethanolamine (NPEA). Is obtained under pressure conditions. The yield of NPEA was improved drastically (>91%) by carrying out the reaction under pot conditions using di-Et carbonate as transesterification agent. Finally activity and selectivity of solid catalyst was explained on the basis of nature of active sites and pore structure of the catalyst.

Industrial & Engineering Chemistry Research published new progress about 101-98-4. 101-98-4 belongs to alcohols-buliding-blocks, auxiliary class Amine,Benzene,Alcohol, name is 2-(Benzyl(methyl)amino)ethanol, and the molecular formula is C8H9BFNO3, Recommanded Product: 2-(Benzyl(methyl)amino)ethanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Reitti, Marcus published the artcileSynthesis of Phenols and Aryl Silyl Ethers via Arylation of Complementary Hydroxide Surrogates, Synthetic Route of 17877-23-5, the publication is Organic Letters (2018), 20(7), 1785-1788, database is CAplus and MEDLINE.

Two transition-metal-free methods to access substituted phenols via the arylation of silanols or hydrogen peroxide with diaryliodonium salts are presented. The complementary reactivity of the two nucleophiles allows synthesis of a broad range of phenols without competing aryne formation, as illustrated by the synthesis of the anesthetic Propofol. Furthermore, silyl-protected phenols can easily be obtained, which are suitable for further transformations.

Organic Letters published new progress about 17877-23-5. 17877-23-5 belongs to alcohols-buliding-blocks, auxiliary class Protection and Derivatization Reagent, name is Triisopropylsilanol, and the molecular formula is C9H22OSi, Synthetic Route of 17877-23-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Semleit, Nina published the artcileControlling the Gold(I)-Catalyzed 1,5-Allenene Reaction: Construction of Fused Rings with Excellent Diastereoselectivity, Category: alcohols-buliding-blocks, the publication is Organic Letters (2021), 23(24), 9635-9639, database is CAplus and MEDLINE.

In the present study, the gold(I)-catalyzed reaction of 1,5-allenenes was controlled in such a way that instead of a [2+3] cycloaddition, a 5-exo-cyclization with the formation of a carbocation occurred. The latter could be trapped with both oxygen and carbon nucleophiles. In the investigated system, fused tricyclic frameworks I (R = Me; R¹ = Me, Cl, Br, etc.; Nu = OMe, OEt, 2-furyl, etc.) with three contiguous stereocenters with excellent chemo- and diastereoselectivity in up to 95% yield were obtained.

Organic Letters published new progress about 86-48-6. 86-48-6 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment,Natural product, name is 1-Hydroxy-2-naphthoic acid, and the molecular formula is C14H19NO8, Category: alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Bingoel, Bahar published the artcileSynthesis and Characterization of Thiophen-3-yl Acetic Acid 4-Pyrrol-1-yl Phenyl Ester and its Conducting Polymers, Quality Control of 23351-09-9, the publication is International Journal of Polymeric Materials (2005), 54(8), 713-730, database is CAplus.

Thiophen-3-yl acetic acid 4-pyrrol-1-yl Ph ester (TAPE) monomer was synthesized via reaction of thiophen-3-yl acetyl chloride with 4-pyrrol-1-yl phenol. Homopolymers were achieved by using electrochem. and chem. polymerization techniques. Copolymers of TAPE with bithiophene or pyrrole were synthesized by potentiostatic electrochem. polymerization in acetonitrile-tetrabutylammonium tetrafluoroborate (TBAFB) solvent-electrolyte couple. The chem. structures were confirmed by both NMR and FTIR. DSC and TGA were used to examine the thermal behavior of the polymers. The morphologies of the films were investigated by SEM. Two-probe technique was used to measure the conductivities of the samples. Moreover, investigations of electrochromic and spectroelectrochem. properties of poly(TAPE-co-BiTh) carried out and the characteristics of dual type electrochromic device based on poly(TAPE-co-BiTh) and poly(3,4-ethylenedioxythiophene) (PEDOT) were reported.

International Journal of Polymeric Materials published new progress about 23351-09-9. 23351-09-9 belongs to alcohols-buliding-blocks, auxiliary class Pyrrole,Benzene,Alcohol, name is 4-(1H-Pyrrol-1-yl)phenol, and the molecular formula is C10H9NO, Quality Control of 23351-09-9.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Pattanaik, Sandip published the artcileCobalt-Catalyzed Selective Synthesis of Disiloxanes and Hydrodisiloxanes, Safety of Triisopropylsilanol, the publication is ACS Catalysis (2019), 9(6), 5552-5561, database is CAplus.

Selective syntheses of sym. siloxanes and cyclotetrasiloxanes are attained from reactions of silanes and dihydrosilanes, resp., with H₂O, and the reactions are catalyzed by a NNN^HtBu Co(II) pincer complex. When phenylsilane was subjected to catalysis with H₂O, a siloxane cage consisting 12 Si and 18 O centers was obtained and remarkably the reaction proceeded with liberation of 3 equiv of H₂ (36 H₂) under mild exptl. conditions. Upon reaction of silane with different silanols, highly selective and controlled syntheses of higher order monohydrosiloxanes and disiloxymonohydrosilanes were achieved by Co catalysis. The liberated H₂ is the only byproduct observed in all of these transformations. Mechanistic studies indicated that the reactions occur via a homogeneous pathway. Kinetic and independent experiments confirmed the catalytic oxidation of silane to silanol, and further dehydrocoupling processes are involved in syntheses of sym. siloxanes, cyclotetrasiloxanes, and siloxane cage compounds, whereas the unsym. monohydrosiloxane syntheses from silanes and silanols proceeded via dehydrogenative coupling reactions. Overall these Co-catalyzed oxidative coupling reactions are based on the Si-H, Si-OH, and O-H bond activation of silane, silanol, and H₂O, resp. Catalytic cycles consisting of Co(II) intermediates probably are operative.

ACS Catalysis published new progress about 17877-23-5. 17877-23-5 belongs to alcohols-buliding-blocks, auxiliary class Protection and Derivatization Reagent, name is Triisopropylsilanol, and the molecular formula is C9H22OSi, Safety of Triisopropylsilanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Cirpan, A. published the artcileConducting polymers of decanedioic acid bis-(4-pyrrol-1-yl-phenyl) ester, Quality Control of 23351-09-9, the publication is Materials Chemistry and Physics (2004), 85(1), 222-226, database is CAplus.

A dipyrrolyl monomer was synthesized via the reaction between 4-pyrrol-1-yl phenol and decanedioyl dichloride. The electrochem. behavior of this monomer was studied. Polymerization of decanedioic acid bis-(4-pyrrol-1-yl-phenyl) ester (DAPE) was achieved by chem. and constant current electrolyzes methods. Copolymerization of DAPE with thiophene was performed by constant potential electrolysis in acetonitrile-tetrabutylammonium tetrafluoroborate (TBAFB), dichloromethane-TBAFB, solvent-electrolyte couples. The chem. structures and properties were investigated by Fourier transform IR spectroscopy, NMR spectroscopy, differential scanning calorimetry and thermal gravimetry anal. The conductivities of the samples were measured by a four-probe technique.

Materials Chemistry and Physics published new progress about 23351-09-9. 23351-09-9 belongs to alcohols-buliding-blocks, auxiliary class Pyrrole,Benzene,Alcohol, name is 4-(1H-Pyrrol-1-yl)phenol, and the molecular formula is C10H9NO, Quality Control of 23351-09-9.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Valliant-Saunders, Karine published the artcileOxidation of Tertiary Silanes by Osmium Tetroxide, Product Details of C9H22OSi, the publication is Inorganic Chemistry (2007), 46(13), 5212-5219, database is CAplus and MEDLINE.

In the presence of an excess of pyridine ligand L, osmium tetroxide oxidizes tertiary silanes (Et₃SiH, ⁱPr₃SiH, Ph₃SiH, or PhMe₂SiH) to the corresponding silanols. With L = 4-tert-butylpyridine (^tBupy), OsO₄(^tBupy) oxidizes Et₃SiH and PhMe₂SiH to yield 100 ± 2% of silanol and the structurally characterized osmium(VI) μ-oxo dimer [OsO₂(^tBupy)₂]₂(μ-O)₂ (1a). With L = pyridine (py), only 40-60% yields of R₃SiOH are obtained, apparently because of coprecipitation of osmium(VIII) with [Os(O)₂py₂]₂(μ-O)₂ (1b). Excess silane in these reactions causes further reduction of the Os^VI products, and similar osmium “over-reduction” is observed with PhSiH₃, Bu₃SnH, and boranes. The pathway for OsO₄(L) + R₃SiH involves an intermediate, which forms rapidly at 200 K and decays more slowly to products. NMR and IR spectra indicate that the intermediate is a monomeric Os^VI-hydroxo-siloxo complex, trans-cis-cis-Os(O)₂L₂(OH)(OSiR₃). Mechanistic studies and d. functional theory calculations indicate that the intermediate is formed by the [3 + 2] addition of an Si-H bond across an O:Os:O fragment. This is the first direct observation of a [3 + 2] intermediate in a σ-bond oxidation, though such species have previously been implicated in reactions of H-H and C-H bonds with OsO₄(L) and RuO₄.

Inorganic Chemistry published new progress about 17877-23-5. 17877-23-5 belongs to alcohols-buliding-blocks, auxiliary class Protection and Derivatization Reagent, name is Triisopropylsilanol, and the molecular formula is C4H10O2, Product Details of C9H22OSi.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Barua, Harsh published the artcileAn ab initio molecular dynamics method for cocrystal prediction: validation of the approach, COA of Formula: C11H8O3, the publication is CrystEngComm (2019), 21(47), 7233-7248, database is CAplus.

Cocrystals offer exciting opportunities to the scientists, with options of tuning their physicochem., biopharmaceutical, and mech. properties simultaneously, which can expand the solid form diversity of drugs. Herein, for overcoming the need for exhaustive exptl. work and improving the chances of success in the selection of coformers, a computational prediction approach has been developed. In this study, a new cocrystal prediction methodol. employing hydrogen bonding tendency, evaluated with the aid of mol. dynamics, has been utilized. For validation, the exptl. results of 145 coformers with 6 drugs have been used. The method was found to significantly reproduce the exptl. results with attractive features of being a simple, easy-to-use protocol, with short computational time. Further, the developed model was used to predict the formation of cocrystals of nitrofurantoin against a library of new coformers. Three out of the four new cocrystals formed were correctly predicted by the developed prediction methodol. The cocrystal formation of 89 coformers out of a total of 145 coformers was correctly predicted. Thus, the reasonable degree of success obtained in predicting and exptl. generating new cocrystals of nitrofurantoin indicates that the developed computational methodol. can play an important role in screening a large library of coformers in the future.

CrystEngComm published new progress about 86-48-6. 86-48-6 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment,Natural product, name is 1-Hydroxy-2-naphthoic acid, and the molecular formula is C11H8O3, COA of Formula: C11H8O3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts