Tag: M.W=150-200

Kiraz, Asli Ozturk published the artcileTheoretical investigation of triazine based a star shape pyrrole monomer, Quality Control of 23351-09-9, the publication is Journal of Macromolecular Science, Part A: Pure and Applied Chemistry (2017), 54(1), 16-23, database is CAplus.

In this work, we report a comprehensive theor. investigation of electroactive star shaped pyrrole functionalized triazine monomer with two main goals. First goal of this work is to explore the phys. and chem. properties of the monomer, then to investigate correlation between the exptl. and the theor. properties of monomer. The scale factor which is calculated from B3LYP/cc-pVDZ was determined as 0.985 for FT-IR and it is an important and reliable contribution to the literature. It is determined that the most appropriate basis set for this mol. The other novel objective of this research is to investigate temperature effect on displacement of chlorine atoms in 2,4,6-trichloro-1,3,5-triazine. This method applied for the first time in the literature for triazines is especially crucial to the synthesis of unsym. triazines.

Journal of Macromolecular Science, Part A: Pure and Applied Chemistry published new progress about 23351-09-9. 23351-09-9 belongs to alcohols-buliding-blocks, auxiliary class Pyrrole,Benzene,Alcohol, name is 4-(1H-Pyrrol-1-yl)phenol, and the molecular formula is C10H9NO, Quality Control of 23351-09-9.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Kemnitzer, William published the artcileDiscovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2. Structure-activity relationships of the 7- and 5-, 6-, 8-positions, Recommanded Product: 3-Morpholinophenol, the publication is Bioorganic & Medicinal Chemistry Letters (2005), 15(21), 4745-4751, database is CAplus and MEDLINE.

As a continuation of our efforts to discover and develop the apoptosis inducing 4-aryl-4H-chromenes as novel anticancer agents, the authors explored the SAR of 4-aryl-4H-chromenes with modifications at the 7- and 5-, 6-, 8-positions. It was found that a small hydrophobic group, such as NMe₂, NH₂, NHEt, and OMe, is preferred at the 7-position. Di-substitution at either the 5,7-positions or the 6,7-positions generally led to a large decrease in potency. Di-substitution at the 7,8-positions, in general, was found to result in potent compounds 7-NMe₂, 7-NHEt, 7-OMe, and 7,8-di-NH₂ analogs were found to have similar SAR for the 4-aryl group, and several 7-substituted and 7,8-di-substituted analogs were found to have similar potencies as the lead compound MX58151 (I) both as caspase activators and inhibitors of cell proliferation.

Bioorganic & Medicinal Chemistry Letters published new progress about 27292-49-5. 27292-49-5 belongs to alcohols-buliding-blocks, auxiliary class Morpholine,Benzene,Phenol, name is 3-Morpholinophenol, and the molecular formula is C10H13NO2, Recommanded Product: 3-Morpholinophenol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Wojtunik-Kulesza, Karolina published the artcilePreliminary Studies on the Effect of Simulated Digestion on the Antioxidant Activity of Monoterpenes, HPLC of Formula: 106-25-2, the publication is Chemistry & Biodiversity (2022), 19(4), e202100995, database is CAplus and MEDLINE.

One of several possible ways of predicting substance bioactivity under in vivo conditions is through simulated studies based on conditions comparable to those within the organism. Having regards to pH and digestive enzymes, such an approach is through simulated digestion. Simulated studies allow gaining an understanding of physiol. conditions and a prediction of compound behavior. The presented studies are based on simulated digestion (SD) to which selected monoterpenes (γ-terpinene, α-terpinene, α-phellandrene, carvone, menthone, isopulegol, α-pinene, β-pinene, terpinene-4-ol, linalool, eucalyptol, p-cymene, citral, citronellal) have been subjected. The procedure included changes pH (2.0 and 8.5) and digestive enzymes (pepsine in gastric stage and pancreatin in duodenal stage) to better understand what goes on within the gastro-intestinal tract. The changes were observed for gastric and duodenal stages, as well as for two phases: oil and water. Obtained results revealed both pos. and neg. influence of gastrointestinal conditions on monoterpenes antioxidant activity. However, pos. impact prevailed (γ-terpinene, citral, eucalyptol, isopulegol, α-pinene). The differentiation in activity can be explained by solubility in oil/water phases and the biotransformation of studied compounds

Chemistry & Biodiversity published new progress about 106-25-2. 106-25-2 belongs to alcohols-buliding-blocks, auxiliary class Natural product, name is cis-3,7-Dimethyl-2,6-Octadien-1-Ol, and the molecular formula is C6H10F3NO, HPLC of Formula: 106-25-2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Meininger, Daniel J. published the artcileSynthesis of tetraphenylporphyrinate manganese(III) siloxides by silyl group transfer from silanethiols, SDS of cas: 17877-23-5, the publication is Journal of Coordination Chemistry (2016), 69(11-13), 1970-1978, database is CAplus.

Reaction of [Mn(OAc)(TPP)] (TPP = dianion of meso-tetraphenylporphine) with both HSSiⁱPr₃ and HSSiPh₃ in the presence of air gives the corresponding siloxide complexes, [Mn(OSiR₃)(TPP)] (R = ⁱPr, Ph), via silyl group transfer from S to O. The new compounds were fully characterized in solution and the solid state and represent rare examples of Mn(III) porphyrinates containing Lewis basic axial ligands. X-ray crystallog. analyses of both complexes reveal very short Mn-O bond distances consistent with the presence of a siloxide ligand. Investigations of the reaction pathway are consistent with initial reduction of [Mn(OAc)(TPP)] to [Mn^II(TPP)] by the silanethiol. Subsequent aerobic oxidation of the reaction mixture is proposed to generate a Mn(III) porphyrinate and the corresponding silanol, which combine to yield the observed siloxide complex. These findings stand in sharp contrast to those of iron(III) porphyrinates, where silanethiolate complexes are stable.

Journal of Coordination Chemistry published new progress about 17877-23-5. 17877-23-5 belongs to alcohols-buliding-blocks, auxiliary class Protection and Derivatization Reagent, name is Triisopropylsilanol, and the molecular formula is C9H22OSi, SDS of cas: 17877-23-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Sakurai, Shuhei published the artcileStructure-antioxidant activity (oxygen radical absorbance capacity) relationships of phenolic compounds, Name: 3-Hydroxyphenylacetic acid, the publication is Structural Chemistry (2022), 33(4), 1055-1062, database is CAplus.

Antioxidant capacity is the extent to which a compound can eliminate reactive oxygen species, and in vitro methods for its chem. evaluation have been proposed. Among these methods, the oxygen radical absorbance capacity (ORAC) assay comes close to the oxidation reaction in the living body because it generates radical species that mimic the lipid peroxyl radical involved in the peroxidation reaction of biol. components and react in a phosphate buffer. In this study, PM7, a semi-empirical MO method, was used to calculate the thermodn. properties (bond dissociation enthalpy, ionisation potential and proton affinity) associated with ORAC. We also applied the clusterwise linear regression anal. as a statistical method for grouping the antioxidants by structure. By analyzing the data for antioxidants, the trend in the hydrophilic ORAC values was determined using the calculated structures and bond dissociation enthalpies of the groups classified according to the presence or absence of oxygen functional groups in the ortho position of phenol. Further studies of indicators other than bond dissociation enthalpy are needed to predict the ORAC of other antioxidants such as flavonoids and indoles.

Structural Chemistry published new progress about 621-37-4. 621-37-4 belongs to alcohols-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Phenol,Natural product, name is 3-Hydroxyphenylacetic acid, and the molecular formula is C8H8O3, Name: 3-Hydroxyphenylacetic acid.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Ye, Juntao published the artcileDirect α-alkylation of primary aliphatic amines enabled by CO₂ and electrostatics, Recommanded Product: 4,4-Diethoxybutan-1-amine, the publication is Nature Chemistry (2018), 10(10), 1037-1041, database is CAplus and MEDLINE.

Primary aliphatic amines are important building blocks in organic synthesis due to the presence of a synthetically versatile NH₂ group. N-functionalization of primary amines is well established, but selective C-functionalization of unprotected primary amines remains challenging. Here, we report the use of CO₂ as an activator for the direct transformation of abundant primary aliphatic amines into valuable γ-lactams under photoredox and hydrogen atom transfer (HAT) catalysis. Exptl. and computational studies suggest that CO₂ not only inhibits undesired N-alkylation of primary amines, but also promotes selective intermol. HAT by an electrostatically accelerated interaction between the in situ-generated neg. charged carbamate and the pos. charged quinuclidinium radical. This electrostatic attraction overwhelms the inherent bond dissociation energies which suggest that HAT should occur unselectively. We anticipate that our findings will open up new avenues for amine functionalizations as well as selectivity control in HAT reactions.

Nature Chemistry published new progress about 6346-09-4. 6346-09-4 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Ether, name is 4,4-Diethoxybutan-1-amine, and the molecular formula is C15H24BNO3, Recommanded Product: 4,4-Diethoxybutan-1-amine.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Ishimoto, Ryo published the artcileHighly selective oxidation of organosilanes to silanols with hydrogen peroxide catalyzed by a lacunary polyoxotungstate, COA of Formula: C9H22OSi, the publication is Angewandte Chemie, International Edition (2009), 48(47), 8900-8904, S8900/1-S8900/11, database is CAplus and MEDLINE.

Divacant lacunary polyoxotungstate (Bu₄N⁺)₄[γ-SiW₁₀O₃₄(H₂O)₂] (1) is an efficient homogeneous catalyst for highly selective oxidation of organosilanes to silanols with 30-60 % aqueous H₂O₂. Various kinds of silanes, Ph₂MeSiH, Et₃SiH, (C₆H₁₃)₃SiH, ^tBuMe₂SiH, Bu₃SiH, ⁱPr₃SiH, (EtO)₃SiH, (BuO)₃SiH, RMe₂SiH (R = Ph, 4-MeOC₆H₄, 4-MeC₆H₄, 4-CF₃C₆H₄, ClCH₂, PhCC, PhCH:CH) containing aryl, alkyl, alkenyl, alkynyl, and alkoxy groups are chemoselectively converted into the corresponding silanols in high yields with only one equiv of aqueous H₂O₂.

Angewandte Chemie, International Edition published new progress about 17877-23-5. 17877-23-5 belongs to alcohols-buliding-blocks, auxiliary class Protection and Derivatization Reagent, name is Triisopropylsilanol, and the molecular formula is C9H22OSi, COA of Formula: C9H22OSi.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Hirano, Tomohiro published the artcileSyndiotactic-specific radical polymerization of N-isopropylacrylamide in toluene at low temperatures in the presence of silyl alcohols, Application In Synthesis of 17877-23-5, the publication is Polymer International (2012), 61(6), 966-970, database is CAplus.

The radical polymerization of N-isopropylacrylamide was carried out in toluene at low temperatures in the presence of silyl alcs., such as triethylsilanol. Poly(N-isopropylacrylamide) with a racemo dyad content of 75% was obtained at – 80° with a 4:1 triethylsilanol to monomer ratio loading. NMR anal. suggests that the mechanism for syndiotactic induction, in the presence of silyl alcs., may be similar to that observed with alkyl alcs. In this case, a 1:2 complex formation, via hydrogen bonding interactions, leads to the induction of syndiotactic specificity. Copyright © 2012 Society of Chem. Industry.

Polymer International published new progress about 17877-23-5. 17877-23-5 belongs to alcohols-buliding-blocks, auxiliary class Protection and Derivatization Reagent, name is Triisopropylsilanol, and the molecular formula is C9H22OSi, Application In Synthesis of 17877-23-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Tanioka, Masaru published the artcileStepwise structural and fluorescent colour conversion in rhodamine analogues based on light and acid stimulations, Category: alcohols-buliding-blocks, the publication is Journal of Materials Chemistry C: Materials for Optical and Electronic Devices (2020), 8(2), 543-549, database is CAplus.

The research and development of multi-stimuli, multi-responsive mols. have attracted considerable attention in chem., biol., and material science. Herein, the authors propose a multi-stimuli-responsive multi-fluorescence system in a single mol. This system is based on the isomerization that involves ring-opening/closing reactions of spirolactones of rhodamine analogs (ABPXs), developed by the authors’ group, which can be independently controlled by light and chem. stimuli. UV light irradiation opens one of the spirolactones to give thermally stable colored isomer (Z) in solution Detailed synthetic and theor. studies reveal that the ring-opening reaction of ABPXs proceeds via the formation of a photo-induced charge separated state, followed by the recombination of the biradicals. Furthermore, the authors explore the structure-kinetic relations and demonstrate that the introduction of electron-donating substituents into the xanthene ring can tune the lifetime of the photo-generated isomer. Chem. stimulation by an acid further promotes the ring-opening reaction to give a red shifted isomer (D). These light and chem. input signals can be converted into output signals of distinct color and fluorescence. The multi-stimuli-responsive multi-color fluorescence could be distinctively expressed through the combinatorial logic gate.

Journal of Materials Chemistry C: Materials for Optical and Electronic Devices published new progress about 27292-49-5. 27292-49-5 belongs to alcohols-buliding-blocks, auxiliary class Morpholine,Benzene,Phenol, name is 3-Morpholinophenol, and the molecular formula is C30H24BrCuN2P, Category: alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Mori, Jiro F. published the artcileMultispecies diesel fuel biodegradation and niche formation are ignited by pioneer hydrocarbon-utilizing proteobacteria in a soil bacterial consortium, Quality Control of 86-48-6, the publication is Applied and Environmental Microbiology (2021), 87(1), e02268, database is CAplus and MEDLINE.

A soil bacterial consortium that was grown on diesel fuel and consisted of more than 10 members from different genera was maintained through repetitive subculturing and was utilized as a practical model to investigate a bacterial community that was continuously exposed to petroleum hydrocarbons. Through metagenomics analyses, consortium member isolation, growth assays, and metabolite identification which supported the linkage of genomic data and functionality, two pioneering genera, Sphingobium and Pseudomonas, whose catabolic capabilities were differentiated, were found to be responsible for the creation of specialized ecol. niches that were apparently occupied by other bacterial members for survival within the consortium. Coexisting genera Achromobacter and Cupriavidus maintained their existence in the consortium through metabolic dependencies by utilizing hydrocarbon biotransformation products of pioneer metabolism, which was confirmed through growth tests and identification of biotransformation products of the isolated strains. Pioneering Sphingobium and Pseudomonas spp. utilized relatively water-insoluble hydrocarbon parent compounds and facilitated the development of a consortium community structure that resulted in the creation of niches in response to diesel fuel exposure which were created through the production of more-water-soluble biotransformation products available to cocolonizers. That these and other organisms were still present in the consortium after multiple transfers spanning 15 years provided evidence for these ecol. niches. Member survival through occupation of these niches led to robustness of each group within the multispecies bacterial community. Overall, these results contribute to our understanding of the complex ecol. relationships that may evolve during prokaryotic hydrocarbon pollutant biodegradation

Applied and Environmental Microbiology published new progress about 86-48-6. 86-48-6 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment,Natural product, name is 1-Hydroxy-2-naphthoic acid, and the molecular formula is C11H8O3, Quality Control of 86-48-6.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts