Tag: M.W=150-200

Safaeian Laein, Sara published the artcileEvaluation of antibacterial and antioxidant activities of essential oil of lime (Citrus aurantifolia) pomace powder, Computed Properties of 124-76-5, the main research area is Citrus aurantifolia pomace essential oil antioxidant antibacterial activity.

This study aimed to determine the chem. compounds, antioxidant and antimicrobial activities of Essential Oil (EO) derived from lime pomace. Gas chromatog./mass spectrometry (GC-MS) was used to determine the major components of the obtained EO. The antioxidant activities of this EO were determined by radical scavenging activity (DPPH) and the Ferric Reducing Antioxidant Power (FRAP) test. For antimicrobial activity, the disk diffusion method was used and the Min. Inhibitory Concentrations (MIC) and the Min. Bactericidal Concentration (MBC) were studied against common foodborne pathogens including; Staphylococcus aureus, Bacillus cereus, Listeria monocytogenes, Escherichia coli, Salmonella typhimurium, and Pseudomonas aeruginosa. The result showed that the Gram-pos. bacteria were more susceptible than gram-neg. bacteria. The result shows that lime pomace powder with IC50 83.061 mg/mL has a high antioxidant capacity and also, the chem. anal. of the EO showed that the EO contained a complex mixture of several components and the main constituents were D-limonene (28.86%), a- terpinene (15.65%) and D-terpinene (12.72%) resp.

Iranian Journal of Chemistry & Chemical Engineering published new progress about Analysis. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Computed Properties of 124-76-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhang, Xue published the artcilePlasma galactose-deficient immunoglobulin A1 and loss of kidney function in patients with immunoglobulin A vasculitis nephritis, Computed Properties of 59-23-4, the main research area is human plasma galactose IgA vasculitis nephritis kidney function; IgA nephropathy; IgA vasculitis nephritis; galactose-deficient IgA1; kidney disease progression.

IgA (IgA) vasculitis nephritis (IgAV-N) is the most common secondary IgA nephropathy (IgAN). Many studies have demonstrated that galactose-deficient IgA1 (Gd-IgA1) in the IgA1 hinge region is associated with the development and also progression of primary IgAN. In this study, we aimed to evaluate the roles of Gd-IgA1 in kidney disease progression in a large Chinese cohort of IgAV-N patients. This cohort study enrolled 112 patients with IgAVN, 15 patients with IgA vasculitis (IgAV) without kidney involvement and 108 patients with IgAN. Plasma IgA1 and Gd- IgA1 levels at kidney biopsy were measured by ELISA. The primary endpoint was a 30% decline in estimated glomerular filtration rate or end-stage renal disease or death. The levels of Gd-IgA1 in IgAV-N and IgAN patients were higher than in healthy controls (mean±SD, 302.86±54.93 U/mL vs. 303.16±59.43 U/mL vs. 281.30±43.74 U/mL, resp.; P = 0.047), as well as compared with those with IgAV without kidney involvement (272.65±53.14 U/mL; P = 0.036). After adjusting clin. data, higher levels of Gd-IgA1 were found to be independently associated with a greater risk for kidney failure [hazard ratio (HR)=1.703 per 1 SD, 95% confidence interval (CI) 1.233-2.352; P = 0.001]. Compared with the first Gd-IgA1 quartile group (as reference), the fourth Gd-IgA1 quartile group retained a predictive value for poor renal outcome (HR = 3.740, 95% CI 1.204-11.619; P = 0.023). These data indicate that Gd-IgA1 levels were similarly elevated in adult patients with IgAN and those with IgAV-N. Moreover, increased Gd-IgA1 levels were associated with both the development and progression of IgAV-N, as observed in IgAN.

Nephrology, Dialysis, Transplantation published new progress about Analysis. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Computed Properties of 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Marcus, Julien published the artcileNano-droplet formation in water/ethanol or isopropanol/mosquito repellent formulations, Category: alcohols-buliding-blocks, the main research area is nanodroplet water ethanol isopropanol mosquito repellent formulation.

It was recently demonstrated that nano-structures were present in water/ethanol/oil systems, where the oil was either octanol or fragrance mols. The goal of the present work is to check if such structures exist also in other, related systems and if a general concept can be deduced from these observations. To this purpose, natural and synthetic mosquito repellent mols. were investigated, which represent nearly all repellents used on the market. For the ternary water/alc. (ethanol or isopropanol)/repellent systems ternary phase diagrams were established. The presence and the ordering of the nano-droplets were checked and characterized with dynamic and static light scattering and conductivity measurements. Based on these results it can be concluded that a nano-ordering with generally an organic continuum exists in hydro-alc. com. mosquito repellents, and thus that these systems are not simply mol. solutions This might have a consequence for diffusion processes in the skin.

Colloids and Surfaces, A: Physicochemical and Engineering Aspects published new progress about Culicidae. 42822-86-6 belongs to class alcohols-buliding-blocks, name is 2-(2-Hydroxypropan-2-yl)-5-methylcyclohexanol, and the molecular formula is C10H20O2, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wolf, Dorina B. published the artcileNucleo-cytoplasmic shuttling of murine RBPJ by Hairless protein matches that of Su(H) protein in the model system Drosophila melanogaster, Synthetic Route of 59-23-4, the main research area is murine protein nucleocytoplasmic shuttling Drosophila melanogaster; CBF1; Drosophila; Hairless, CSL; Notch signal transduction; Nucleo-cytoplasmic transport; Protein availability; RPBJ; Su(H); Transcription repression.

CSL transcription factors are central to signal transduction in the highly conserved Notch signaling pathway. CSL acts as a mol. switch: depending on the cofactors recruited, CSL induces either activation or repression of Notch target genes. Unexpectedly, CSL depends on its cofactors for nuclear entry, despite its role as gene regulator. In Drosophila, the CSL homolog Suppressor of Hairless (Su(H)), recruits Hairless (H) for repressor complex assembly, and eventually for nuclear import. We recently found that Su(H) is subjected to a dynamic nucleo-cytoplasmic shuttling, thereby strictly following H subcellular distribution. Hence, regulation of nuclear availability of Su(H) by H may represent a new layer of control of Notch signaling activity. Here we extended this work on the murine CSL homolog RBPJ. Using a ‘murinized’ fly model bearing RBPJwt in place of Su(H) at the endogenous locus we demonstrate that RBPJ protein likewise follows H subcellular distribution. For example, overexpression of a H*NLS3 protein variant defective of nuclear import resulted in a cytosolic localization of RBPJ protein, whereas the overexpression of a H*NES protein variant defective in the nuclear export signal caused the accumulation of RBPJ protein in the nucleus. Evidently, RBPJ is exported from the nucleus as well. Overall these data demonstrate that in our fly model, RBPJ is subjected to H-mediated nucleo-cytoplasmic shuttling as is Su(H). These data raise the possibility that nuclear availability of mammalian CSL proteins is likewise restricted by cofactors, and may hence present a more general mode of regulating Notch signaling activity.

Hereditas (London, United Kingdom) published new progress about Cytoplasm. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Synthetic Route of 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Welsink-Karssies, Mendy M. published the artcileThe 1-13C galactose breath test in GALT deficient patients distinguishes NBS detected variant patients but does not predict outcome in classical phenotypes, Recommanded Product: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, the main research area is GALT1 GAL1P prognosis diagnosis galactosemia movement disorder infant; 13CO2; galactose oxidation; inborn error of metabolism; isotope ratio mass spectrometry.

Classical galactosemia (CG) patients frequently develop long-term complications despite early dietary treatment. The highly variable clin. outcome is poorly understood and a lack of prognostic biomarkers hampers individual prognostication and treatment. The aim of this study was to investigate the association between residual galactose oxidation capacity and clin. and biochem. outcomes in CG patients with varying geno- and phenotypes. The noninvasive 1-13C galactose breath test was used to assess whole body galactose oxidation capacity. Participants received a 7 mg/kg oral dose of 1-13C labeled galactose. The galactose oxidation capacity was determined by calculating the cumulative percentage dose of the administered galactose (CUMPCD) recovered as 13CO2 in exhaled air. Forty-one CG patients (5-47 years) and four adult controls were included. The median galactose oxidation capacity after 120 min (CUMPCDT120) of 34 classical patients (0.29; 0.08-7.51) was significantly lower when compared to two homozygous p.Ser135Leu patients (9.44; 8.66-10.22), one heterozygous p.Ser135Leu patient 18.59, four NBS detected variant patients (13.79; 12.73-14.87) and four controls (9.29; 8.94-10.02). There was a clear correlation between Gal-1-P levels and CUMPCDT120 (P < .0005). In the classical patients, the differences in CUMPCDT120 were small and did not distinguish between patients with poor and normal clin. outcomes. The galactose breath test distinguished classical patients from homo- and heterozygous p.Ser135Leu and NBS detected variant patients, but was not able to predict clin. outcomes in classical patients. Future studies are warranted to enable individualised prognostication and treatment, especially in NBS variants with galactose oxidation capacities in the control range. Journal of Inherited Metabolic Disease published new progress about Diagnosis. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Recommanded Product: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Liu, Yantao published the artcileComparison and characterization of galactomannan at different developmental stages of Gleditsia sinensis Lam., HPLC of Formula: 59-23-4, the main research area is galactomannan Gleditsia growth; Galactomannan deposition; Gleditsia sinensis Lam.; Mannose to galactose ratio; Rheological properties; Solubility.

Pods from a Gleditsia sinensis Lam. tree were collected and the galactomannan content and other properties were determined at their different developmental stages. In green and immature seed, galactomannan was substituted to a great extent with a mannose to galactose (M/G) ratio of 2.4 from crude polysaccharides. During late galactomannan deposition, it was substituted to a lower extent and this ratio increased rapidly, reaching a M/G ratio of 3.1. Average mol. weight (Mw) of the extracted polysaccharides first increased, reached the maximum (1.19 × 106) at 17 wk after flowering (WAF), and then decreased. These changes might result from primary galactomannan biosynthesis and from galactose removal by α-galactosidase in the endosperm. The solubility of crude polysaccharides decreased with increased M/G ratio and maximum solubility was more than 89% that collected at 13 WAF. Rheol. properties showed that apparent viscosity was largely influenced by the mol. weight and M/G ratio of galactomannans.

Carbohydrate Polymers published new progress about Flowering. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, HPLC of Formula: 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Padra, Medea published the artcileHelicobacter suis infection alters glycosylation and decreases the pathogen growth inhibiting effect and binding avidity of gastric mucins, SDS of cas: 59-23-4, the main research area is Helicobacter suis infection glycosylation gastric mucin.

Helicobacter suis is the most prevalent non-Helicobacter pylori Helicobacter species in the human stomach and is associated with chronic gastritis, peptic ulcer disease, and gastric mucosa-associated lymphoid tissue (MALT) lymphoma. H. suis colonizes the gastric mucosa of 60-95% of pigs at slaughter age, and is associated with chronic gastritis, decreased weight gain, and ulcers. Here, we show that exptl. H. suis infection changes the mucin composition and glycosylation, decreasing the amount of H. suis-binding glycan structures in the pig gastric mucus niche. Similarly, the H. suis-binding ability of mucins from H. pylori-infected humans is lower than that of noninfected individuals. Furthermore, the H. suis growth-inhibiting effect of mucins from both noninfected humans and pigs is replaced by a growth-enhancing effect by mucins from infected individuals/pigs. Thus, Helicobacter spp. infections impair the mucus barrier by decreasing the H. suis-binding ability of the mucins and by decreasing the antiprolific activity that mucins can have on H. suis. Inhibition of these mucus-based defenses creates a more stable and inhabitable niche for H. suis. This is likely of importance for long-term colonization and outcome of infection, and reversing these impairments may have therapeutic benefits.

Mucosal Immunology published new progress about Gastritis. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, SDS of cas: 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Hu, Weiwei published the artcilePhysicochemical and macromolecule properties of RG-I enriched pectin from citrus wastes by manosonication extraction, Recommanded Product: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, the main research area is rhamnogalacturonan pectin citrus waste manosonication extraction physicochem macromol property; Manosonication extraction; Property characterisation; RG-I enriched pectin.

The properties of pectin extracted from mandarin citrus peels by manosonication extraction (MSp) were systematically studied and compared with pectin obtained by the conventional maceration method (CMp). The yield of MSp (25.5%) was significantly higher than that of CMp (18.3%), while MSp exhibited two Mw fraction distributions. Monosaccharide anal. demonstrated that MSp had more branched RG-I regions (78.3 mol%) than CMp (36.6 mol%) with a high content of arabinose and galactose. The branched-chain morphol. characteristics of samples were directly imaged by at. force microscopy. The MSp exhibited a significantly lower degree of methoxylation than CMp by FT-IR and NMR anal., but X-ray diffraction anal. showed little difference in the level of crystallinity. Moreover, MSp and CMp showed non-Newtonian behavior, and the increasing order of apparent viscosities was 1.0 w/v% MSp < 1.0 w/v% CMp < 2.0 w/v% CMp < 2.0 w/v% MSp. Thermal anal. and weight loss measurements indicated MSp exhibited greater thermal stability. The results also indicated that both MSp and CMp significantly enhanced the emulsion activity at high concentrations; the emulsions containing 1.5 w/v% pectin showed no phase separation over 21 days, suggesting that MSp could be a potential effective stabilizer in the food and beverage industry. International Journal of Biological Macromolecules published new progress about Beverages. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Recommanded Product: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Qin, Zhao published the artcileStructure, rheological, thermal and antioxidant properties of cell wall polysaccharides from Chinese quince fruits, Application of (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, the main research area is Chaenomeles cell wall polysaccharide structure rheol thermal antioxidant property; Antioxidant activity; Cell wall polysaccharides; Chinese quince; Hemicelluloses; Pectins.

To investigate the composition and structural characteristics of cell wall polysaccharides, three pectic fractions and two hemicellulose fractions, namely water-soluble pectin (WSP), chelator-soluble pectin (CSP), sodium carbonate-soluble pectin (NSP), 1 mol/L KOH soluble hemicellulose (KSH-1) and 4 mol/L KOH soluble hemicellulose (KSH-2), were isolated from Chinese quince fruits. The five fractions exhibited structural and compositional variation. The results showed NSP was the predominant cell wall polysaccharide fraction in the fruit. All pectic fractions had a low degree of esterification (31.7-42.4%). WSP fraction had the highest thermal stability among the five fractions. The polysaccharide chain lengths ranged from 19.4 nm to 121.4 nm. CSP had the highest mol. weight, giving it also the highest solution viscosity. NMR spectra revealed that NSP was composed of RG-I and galacturonic acid main chains, KSH-1 was composed of 1,4-β-D-Xylp backbone attached to 1,5-a-L-Araf units. Among the five fractions, CSP has the highest DPPH radical scavenging activity while KSH-1 has the highest reducing power. This study can contribute to the applications of Chinese quince fruit polysaccharides in food and pharmaceutical industries.

International Journal of Biological Macromolecules published new progress about Cell wall. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Application of (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yu, Hang published the artcileExtraction of Cinnamomum camphora chvar. Borneol essential oil using neutral cellulase assisted-steam distillation: optimization of extraction, and analysis of chemical constituents, Product Details of C10H18O, the main research area is Cinnamomum camphora borneol essential oil.

In this study, neutral cellulase assisted-steam distillation (NCSD) was first developed to extract BEO, followed by optimizing NCSD through single-factor test (SFT) and response surface methodol. (RSM). The processing conditions of NCSD were optimized as follows: addition of neutral cellulase (0.36 FPU/g of fresh leaves), duration of enzymolysis (5.39 h), temperature (51.47°C), and pH (6.15). The predicted yield of BEO using NCSD was 1.03% within 95% confidence intervals of the actual yield of BEO (1.03 ± 0.03%), which was 58% higher than the yield of BEO using conventional steam distillation (SD) without neutral cellulase pre-treatment (0.65 ± 0.04%). Moreover, chem. constituents of BEO using NCSD and SD were evaluated and compared. Results show that 62 volatile compounds were identified, and majority of functional compounds in the BEO using NCSD and SD were detected simultaneously, e.g. borneol, β-pinene, and β-cadinene. A significantly higher proportion of compounds with relatively lower mol. weight (MW) ranging from 130 to 150 and higher MW ranging from 205 to 225 were detected in the BEO using NCSD, which may contribute to a stronger flavoring impact and influence the overall flavor profile of the BEO. Therefore, significance of this study is to develop the NCSD as a more effective method than the SD for extracting the BEO from Cinnamomum camphora chvar. Borneol fresh leaves without compromising its quality and remaining the majority of chem. consitutents unchanged.

Industrial Crops and Products published new progress about Cell wall. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Product Details of C10H18O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts