Tag: M.W=150-200

Niteeshkumar published the artcileChemical analysis and antibacterial activity of Black turmeric (Curcuma caesia Roxb.) genotypes, Synthetic Route of 124-76-5, the main research area is Curcuma Bacillus Streptococcus Pseudomonas Shigella.

Curcuma caesia Roxb. is an important, lesser known, non-conventional medicinal plant belonging to Zingiberaceae family. The eight genotypes selected were GKM-1, GKM-2, GKB-3, GKB-4, GKJ-5, GMV-6, GKT-29 and GKK-30 were collected from different regions as presented in (Table 1). The Rhizomes of black turmeric genotypes were extracted with methanol at room temperature for 18 h. Preliminary phytochem. anal. revealed the presence of tannins, flavonoid and phenol. The highest phenol GMV-6 (1.46 mg-1g), tannin GKT-29 (0.69 mg-1g) and flavonoid GMV-6 (1.64 mg-1g) was recorded. The bioactive compounds of Curcuma caesia Roxb have been evaluated using GC-MS. Totally 19 major compounds were identified from eight genotypes. The major constituents were identified in the methanolic rhizome extracts were Curcumenol in GKM-1(20.35%), GKB-3(12.96%), GKB-4(15.67%) and in GKT-29(16.17%), Curcumenone in GKM-1(16.07%), GKM-2(25.03%), GKB-3(29.30%) and in GKT-29(22.25%), Epicurzerenone in GKM-1(12.93%) and GKM-2(21.82%), 9-12, Octadecadionic acid in GKM-1(5.54%), GKB-3(2.81%) and in GKB-4(3.59%), 2-Bornanone in GKM-2(4.38%) and in GKB3(5.38%), 4H-Pyran-4-one, 2,3-dihydro-3,5-dihydroxy-6-methyl- in GKB-3(8.91%), GKB-4(24.44%), GKJ-5(19.82%) and GKT-29(9.88%), Isoborneol in GKM-2(1.54%) and GKB-3(3.67%) and Eucalyptol in GKM-2(1.17%). The research findings have shown that the rhizome of C. caesia is extensively rich in secondary metabolites. The extracts were assessed for their potential antibacterial activity against Gram pos. and Gram neg. bacteria viz., Bacillus cereus, Bacillus subtilis, Streptococcus agalactiae, Escherichia coli, Pseudomonas aeruginosa and Shigella flexneri. The rhizome extracts of black turmeric genotypes exhibit pos. results against the Gram pos. bacteria.

Pharma Innovation published new progress about Bacillus cereus. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Synthetic Route of 124-76-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chankaew, Chaiyos published the artcileKaffir lime leaf extract mediated synthesis, anticancer activities and antibacterial kinetics of Ag and Ag/AgCl nanoparticles, Formula: C10H20O2, the main research area is silver chloride nanoparticle kaffir lime leaf antibacterial kinetic property.

A facile phytosynthesis of Ag/AgCl and Ag nanoparticles (NPs) was developed using a crude water extract of Citrus hystrix DC (kaffir lime) leaves. The phytochem. and chloride contents of the extract, and various synthesis parameters were studied. The obtained Ag/AgCl and Ag NPs were of the cubic phase and mostly spherical in shape. Particle sizes of the yielded NPs were distributed in a narrow range with an average size of 20 and 38 nm for the Ag/AgCl and Ag NPs, resp. The reducing function of the phytochems. and the stabilizing ability of gelatin were demonstrated. The NPs showed significant anti-proliferative activities against the carcinoma HCT 116 and adenocarcinoma Caco-2 colorectal cell lines, but had a neg. effect toward human fibroblasts. The NPs exhibited excellent antibacterial activities against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Bacillus cereus. The inactivation kinetics obtained in the presence of the NPs showed a biphasic behavior that can be explained by the Cerf model.

Particuology published new progress about Bacillus cereus. 42822-86-6 belongs to class alcohols-buliding-blocks, name is 2-(2-Hydroxypropan-2-yl)-5-methylcyclohexanol, and the molecular formula is C10H20O2, Formula: C10H20O2.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Berglund, Jennie published the artcileThe structure of galactoglucomannan impacts the degradation under alkaline conditions, HPLC of Formula: 59-23-4, the main research area is galactoglucomannan degradation alk hydrolysis sugar mol dynamic simulation.

Galactoglucomannan (GGM) from spruce was studied with respect to the degradation behavior in alk. solution Three reference systems including galactomannan from locust bean gum, glucomannan from konjac and the linear water-soluble CM-cellulose were studied with focus on mol. weight, sugar composition, degradation products, as well as formed oligomers, to identify relative structural changes in GGM. Initially all mannan polysaccharides showed a fast decrease in the mol. weight, which became stable in the later stage. The degradation of the mannan polysaccharides could be described by a function corresponding to the sum of two first order reactions; one slow that was ascribed to peeling, and one fast that was connected with hydrolysis. The galactose side group was stable under conditions used in this study (150 min, 90°C, 0.5 M NaOH). This could suggest that, apart from the covalent connection to C6 in mannose, the galactose substitutions also interact non-covalently with the backbone to stabilize the structure against degradation Addnl., the combination of different backbone sugars seems to affect the stability of the polysaccharides. For CM-cellulose the degradation was linear over time which further suggests that the structure and sugar composition play an important role for the alk. degradation Mol. dynamics simulations gave details about the conformational behavior of GGM oligomers in water solution, as well as interaction between the oligomers and hydroxide ions.

Cellulose (Dordrecht, Netherlands) published new progress about Base hydrolysis. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, HPLC of Formula: 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kansandee, Wiratchanee published the artcileCharacterization and Bifidobacterium sp. growth stimulation of exopolysaccharide produced by Enterococcus faecalis EJRM152 isolated from human breast milk, Product Details of C6H12O6, the main research area is Bifidobacterium exopolysaccharide Enterococcus breast milk; Bifidobacterium sp.; Exopolysaccharides; Human breast milk; Prebiotics.

Sixty lactic acid bacteria (LAB) isolated from human breast milk were screened for exopolysaccharides (EPS) production EPS characterization and Bifidobacterium sp. growth support were investigated. The highest EPS-producing isolate was EJRM152 which identified as Enterococcus faecalis (98% similarity) based on the 16S rDNA gene sequence. Product yield coefficient (YEPS/x) and EPS production were 3.68 and 4.32 g/l, resp. Crude EPS was purified by DEAE-cellulose and a Sephacryl S-400 column, and it revealed different mol. weights and molar ratios of glucose, galactose, rhamnose, arabinose and fructose. FT-IR spectroscopy of EPS showed functional groups including hydroxyl and carbonyl. B. animalis TISTR 2194, B. breve TISTR 2130, B. bifidum TISTR 2129, and B. longum TISTR 2195 grew well in media containing EPS, comparing with com. prebiotics. Results suggest that EPS produced by E. faecalis EJRM152 could be a potential candidate prebiotic.

Carbohydrate Polymers published new progress about Bifidobacterium. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Product Details of C6H12O6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Li, Yan-xiao published the artcilePreparation, characterization, and prebiotic activity of manno-oligosaccharides produced from cassia gum by a glycoside hydrolase family 134 β-mannanase, Synthetic Route of 59-23-4, the main research area is prebiotic mannooligosaccharide cassia gum mannanase; Cassia gum; Characterization; Manno-oligosaccharides; Prebiotic activity; β-Mannanase.

To produce mannooligosaccharides from cassia gum, a mutated glycoside hydrolase family 134 β-mannanase gene (mRmMan134A) from Rhizopus microsporus var. rhizopodiformis F518 was expressed in Pichia pastoris and a high expression level (3680 U mL-1) was obtained through high cell d. fermentation mRmMan134A exhibited maximum activity at pH 5.5 and 50°C. It was then subjected to hydrolyze cassia gum with 70.6% of overall yield of mannooligosaccharides. From the hydrolyzate, seven components (F1-F7) were separated and identified as mannose, mannobiose, galactose, mannotriose, mannotetraose, 61-α-D-galactosyl-β-D-mannobiose, and mannopentaose, resp. According to in vitro fermentation, the mannooligosaccharides were able to promote the growth of three Bifidobacterium strains and six Lactobacillus strains with 3.0-fold increment in culture absorbance, and these strains preferred mannooligosaccharides with DP 2-3 rather than those with DP 4-5. Novel mannooligosaccharides from cassia gum with promising prebiotic activity were provided in the present study.

Food Chemistry published new progress about Bifidobacterium. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Synthetic Route of 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wu, Mengqi published the artcileStructural elucidation and immunomodulatory activity of a neutral polysaccharide from the Kushui Rose (Rosa setate x Rosa rugosa) waste, Recommanded Product: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, the main research area is structural immunomodulatory activity neutral polysaccharide Kushui waste WSRP1b; Immunomodulatory; Kushui Rose (Rosa setate x Rosa rugosa) waste; Polysaccharide; Structure.

In this present study, the structure and immunomodulatory activity of a novel polysaccharide (WSRP-1b) from Kushui rose (Rosa setate x Rosa rugosa) waste were investigated. Structure characterization demonstrated that WSRP-1b had a weight-average mol. weight of 1.11 × 104 Da and consisted of glucose (42.6%), mannose (21.4%), arabinose (9.9%), xylose (2.2%), and galactose (23.9%). Its backbone was composed of 1, 4-linked α-Glcp, 1, 4-linked β-Glcp, and 1, 4-linked β-Manp, with branches of 1, 4-linked α-Glcp and 1, 4-linked β-Manp substituted at C-6 by 1, 6-linked β-Galp. The branches mainly contained 1, 5-linked Araf, terminal arabinose and terminal glucose. Bioactivity assays showed that WSRP-1b had immunomodulatory activity by enhancing phagocytosis of macrophages, increasing production of ROS, NO, cytokines (IL-6, TNF-α), and activating NF-κB signaling pathway. These results suggested that it could be developed as a potential and safe immunomodulatory agent in fields of pharmacol. or functional foods.

Carbohydrate Polymers published new progress about Immunomodulators. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Recommanded Product: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Salomon, Lysanne published the artcileComparison of the phenolic compound profile and antioxidant potential of Achillea atrata L. and Achillea millefolium L, Safety of rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, the main research area is phenolic compound antioxidant Achillea atrata millefolium; Achillea atrata L.; Achillea millefolium L.; DPPH; antioxidant activity; phenolic metabolome.

In the present study, Achillea atrata L. and A. millefolium L. were compared for the first time with regard to their phenolic compound profile and antioxidant activity by applying the 2,2-diphenyl-picryl hydrazyl radical assay. For this purpose, aerial plant parts were consecutively extracted with solvents of increasing polarity (dichloromethane, n-butanol, Et acetate), revealing that the A. atrata Et acetate fraction showed the highest antioxidant activity with an IC50 value of 12.2 ±0.29 μg/mL compared to 17.0 ± 0.26 μg/mL for A. millefolium. Both species revealed the presence of luteolin, apigenin, centaureidin, and nevadensin exclusively in this most polar fraction, which are known as effective 2,2-diphenyl-picryl hydrazyl radical scavengers. The antioxidant capacity of the aforementioned fractions strikingly correlated with their total phenolic contents, which was highest in the Et acetate fraction of A. atrata. Characterization of the metabolite profiles of both Achillea species showed only marginal differences in the presence of key compounds, whereas the concentrations of individual compounds appeared to be species-specific. Our results suggest that A. atrata, based on its compound pattern and bioactivity characteristics, has similar qualities for phytotherapy as A. millefolium.

Molecules published new progress about Achillea atrata. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Safety of rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhang, Jixian published the artcileEffects of subcritical water extraction microenvironment on the structure and biological activities of polysaccharides from Lentinus edodes, SDS of cas: 59-23-4, the main research area is Lentinus polysaccharide structure subcritical water extraction microenvironment antioxidant antitumor; Biological activities; Microenvironment; Polysaccharides; Structure; Subcritical water.

In the present study, we investigated the effects of subcritical water microenvironment on the structure and biol. activities of polysaccharides from Lentinus edodes. The results showed that, under different SWE conditions (100-150°C for 15 min, and 150°C for 10-30 min), all the polysaccharides were heteropolysaccharides and consisted of glucose, mannose and galactose with different molar ratios. In addition, FT-IR results showed that all samples were typical β-pyranose and protein-free polysaccharides. Moreover, Congo red staining and at. force microscope (AFM) analyses showed that when the temperature was above 150°C for 15 min, the triple-helix structure no longer existed. Furthermore, various polysaccharides had varying degrees of inhibitory effect on HepG2 cells and MCF-7 cells in vitro. These findings indicated that subcritical water microenvironment has an extremely important effect on the structure and bioactivities of polysaccharides. The polysaccharides may be extracted more effectively by changing the subcritical water microenvironment.

International Journal of Biological Macromolecules published new progress about Acid hydrolysis. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, SDS of cas: 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Jia, Yanan published the artcileThe structural characteristic of acidic-hydrolyzed corn silk polysaccharides and its protection on the H2O2-injured intestinal epithelial cells, Application In Synthesis of 59-23-4, the main research area is corn silk polysaccharide acidic hydrolysis hydrogen peroxidase cell injury; Acidic-hydrolyzation; Antioxidant activity; Corn silk polysaccharides; Intestinal epithelial cells.

This work aims to describe the purification and characterization of acidic-hydrolyzed corn silk polysaccharides (AH-CSP) and evaluate their protection on the H2O2-injured intestinalepithelial cells (IEC-6). Two fractions named AHP-1 and AHP-2 were obtained from AH-CSP, and physicochem. properties of them were investigated by gel permeation chromatog. (GPC), gas chromatog. (GC), NMR (NMR), fourier transform IR (FT-IR) spectroscopy, scanning electronic microscopy (SEM), and Congo red test. Results showed that AHP-1 (2.80 x 104 Da) and AHP-2 (1.25 x 104 Da) were consisted of xylose, mannose, galactose, rhamnose, arabinose, and glucose. AHP-1 and AHP-2 had strong scavenging activities on 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2-Azobis-3-ethylbenzthiazoline-6-sulfonic acid (ABTS), and OH· free radicals. Furthermore, pretreatment with AHP-2 could protect the H2O2-injured IEC-6 cells by effectively scavenging the overproduced reactive oxygen species (ROS) and regulating of Kelch-like ECH-associated protein 1(Keap1)/ nuclear factor erythroid 2-related factor 2 (Nrf2) signal pathway.

Food Chemistry published new progress about Acid hydrolysis. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Application In Synthesis of 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wandee, Yuree published the artcileYield and structural composition of pomelo peel pectins extracted under acidic and alkaline conditions, Recommanded Product: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, the main research area is pomelo peel pectin yield structural composition acidic alk.

Extraction of pectin from pomelo peel was performed using water, acid and alk. solutions with a microwave power of 1100 W for 2 min, and yield and structural/chem. characteristics of the extracted pectins were investigated. Extraction of pectin with water gave the lowest yield (6.5%, dry weight basis). The water-extracted pectin contained the highest amount of neutral sugar (29.5%), while equivalent mol. weight (MWeq) and degree of methylation (DM) were 43 kDa and 29.7%, resp. Extraction of pectin with HCl solutions at concentrations of 25, 50, 100 and 200 mM resulted in a significant increase of pectin yields (12.1-20.5%) and pectins with high amount of galacturonic acid (83.3-85.6%). The MWeq and DM of the acid-extracted pectins ranged from 171 to 368 kDa and 53.9-82.5%, resp. Compared to the acid, extraction with NaOH solutions at the same concentrations provided higher yields (13.9-24.2%), smaller size (142-187 kDa) and lower DM (<1.7%) pectins, while amount of galacturonic acid was comparable. The highest yield of extraction was found at a concentration of 50 mM for both HCl and NaOH solutions Extraction of pomelo peel with 50 mM NaOH solution by reduction of the microwave power to 550 W and extending the extraction time to 15 min resulted in an increase of pectin yield (29.2%) and pectin with smaller size (76 kDa). Food Hydrocolloids published new progress about Acid hydrolysis. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Recommanded Product: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts