Tag: M.W=150-200

Molaei, Somayeh; Moeini, Nazanin; Ghadermazi, Mohammad published the artcile< Synthesis of CoFe2O4 @Amino glycol/Gd nanocomposite as a high-efficiency and reusable nanocatalyst for green oxidation of sulfides and synthesis of 5-substituted 1H-tetrazoles>, Category: alcohols-buliding-blocks, the main research area is cobalt spinel ferrite magnetite nanoparticles immobilized covalently amino glycol; gadolinium nanocomposite preparation; nickel ferrate magnetite nanoparticles supported on silica immobilized covalently; amino glycol gadolinium nanocomposite preparation; sulfinyl green preparation; tetrazole green preparation.

In this study, a novel gadolinium 2-amino-2-methyl-1,3-propanediol (amino glycol) complex immobilized covalently on CoFe2O4 magnetite nanoparticles was synthesized. The nanocatalyst was characterized thoroughly using thermogravimetric analyzes (TGA), FT-IR spectroscopy, SEM (SEM), energy dispersive X-ray (EDX), inductively coupled plasma optical emission spectroscopy (ICP-OES), vibrational sample magnetometry (VSM), and powder X-ray diffraction (PXRD). CoFe2O4 @amino glycol/Gd was found to be efficient for the oxidation of sulfides to sulfinyl R1S(O)R2 [R1 = Et, Ph, Bn, etc.; R2 = Me, Et, Ph, etc.] and synthesis of 5-substituted 1H-tetrazoles I [R3 = Ph, Bn, 4-HOC6H4, etc.] at mild reaction conditions in the green medium. The influences of reaction temperature, solvent, and the amount of catalysts were studied. The best results were obtained in water and without organic solvent condition for 5-substituted 1H-tetrazoles and oxidation of sulfides, resp. The catalyst was easily collected via an external magnetic field and further reused at least 6 times without a significant decrease in catalytic activity. The wide applicability of the catalyst, ease of catalyst separation, its reusability capacity, and importantly reaction operation in a green medium and elimination of hazardous organic solvents were the advantages of this catalyst.

Journal of Organometallic Chemistry published new progress about Functional groups, sulfinyl group. 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wu, Han; Li, Rui-Ting; Dong, Jun-Feng; Jiang, Nan-Ji; Huang, Ling-Qiao; Wang, Chen-Zhu published the artcile< An odorant receptor and glomerulus responding to farnesene in Helicoverpa assulta (Lepidoptera: Noctuidae)>, Category: alcohols-buliding-blocks, the main research area is Helicoverpa larva glomerulus odorant receptor farnesene oviposition index; Farnesene; Glomeruli; Labeled-line; Odorant receptor.

Terpenoids emitted from herbivore-damaged plants were found to play an important role in regulating tritrophic interactions. How herbivores and their natural enemies perceive terpenoids has not been thoroughly elucidated to date. Using in vivo calcium imaging, we found in this study that farnesene activates one glomerulus in the antennal lobe of female Helicoverpa assulta. The response induced by a mixture of farnesene isomers is stronger than that elicited by E-β-farnesene alone. In the Xenopus oocyte expression system, HassOR23/ORco is narrowly tuned to farnesene isomers and compounds with similar structures. Finally, the behavioral studies showed that the farnesene isomers have an inhibitory effect on oviposition of female H. assulta, but have an attractive effect on host searching of Campoletis chlorideae, the key endoparasitoid of H. assulta larvae. These results demonstrate that farnesene isomers are encoded by a labeled-line mode in the olfactory system of female H. assulta, suggesting that farnesene as a chem. signal from plants has important behavioral relevance and evolutionary implications in the tritrophic context.

Insect Biochemistry and Molecular Biology published new progress about Antennal lobe. 78-70-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C10H18O, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Couto, Hyrla Grazielle Silva de Araujo; Blank, Arie Fitzgerald; de Oliveira e Silva, Ana Mara; Nogueira, Paulo Cesar de Lima; Arrigoni-Blank, Maria de Fatima; Nizio, Daniela Aparecida de Castro; Pinto, Jessika Andreza de Oliveira published the artcile< Essential oils of basil chemotypes: Major compounds, binary mixtures, and antioxidant activity>, Reference of 78-70-6, the main research area is essential oil basil genotype antioxidant eugenol; 1,8 cineole (PubChem CID: 2758); Antagonism; Eugenol; Eugenol (PubChem CID: 3314); Geranial (PubChem CID: 638011); Linalool (PubChem CID: 6549); Methyl chavicol (PubChem CID: 8815); Methyl cinnamate (PubChem CID: 637520); Neral (PubChem CID: 643779); Ocimum; Synergism; Volatile oil.

The antioxidant potential of the essential oils (EO) of 24 basil genotypes was assessed by 4 distinct in vitro evaluation methods. Different combinations of the major compounds found in the EO were also tested to identify those combinations responsible for the antioxidant activity of the volatile oils and verify the occurrence of synergism or antagonism between them. Results indicate that 9 EO exhibited promising antioxidant potential, with at least 52.68% of inhibition of the linoleic acid peroxidation at 10 μL/mL and 76.34% of inhibition of the DPPH· radical at 1 μL/mL. The major compound eugenol had the highest antioxidant activity. The antioxidant activity of these EO cannot be explained solely by the presence of the major compounds Despite the influence of eugenol, the antioxidant activity is also related to the synergism between other minor compounds found in the EO. This fact confers a potent antioxidant activity to some basil EO.

Food Chemistry published new progress about Antioxidants. 78-70-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C10H18O, Reference of 78-70-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Arruda, Henrique Silvano; Silva, Eric Keven; Pereira, Gustavo Araujo; Meireles, M. Angela A.; Pastore, Glaucia Maria published the artcile< Inulin thermal stability in prebiotic carbohydrate-enriched araticum whey beverage>, Name: (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol, the main research area is araticum whey beverage inulin carbohydrate prebiotic thermal stability.

Inulin is a prebiotic carbohydrate widely used in the food industry due to its health-related claims and its ability to modify/improve the technol. properties of food products. However, industrial processes such as thermal treatments, can cause structure changes in prebiotic carbohydrates affecting their health benefits and technol. properties, but these aspects have received little attention. Therefore, this study aimed to evaluate the impact of thermal treatments (70-100°C/60 s) on inulin chem. stability in a dairy system, araticum flavoured whey beverage. Compared with untreated whey beverage, the thermally processed whey beverages did not exhibit any changes in pH (5.59), total soluble solids (24.63-25.19°Brix), glucose (16.11-17.97 mg/mL), fructose (17.75-19.49 mg/mL), sucrose (89.00-94.14 mg/mL) and lactose (61.59-67.19 mg/mL). The chromatog. anal. displayed no significant differences in content (GF2-GF4 ranged from 3.04 to 3.28 mg/mL) and profile of inulin (average DP = 10) between untreated and thermally processed beverages, showing that inulin had strong ability to resist thermal degradation in a dairy system. This study has provided consistent and clear results regarding inulin thermal stability, showing that inulin can be successfully added in thermally processed com. dairy beverages without prejudice to their prebiotic properties.

LWT–Food Science and Technology published new progress about Annona crassiflora. 492-62-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Name: (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Lenger, Stacy M.; Bradley, Megan S.; Thomas, Debbie A.; Bertolet, Marnie H.; Lowder, Jerry L.; Sutcliffe, Siobhan published the artcile< D-mannose vs other agents for recurrent urinary tract infection prevention in adult women: a systematic review and meta-analysis>, Product Details of C6H12O6, the main research area is human D mannose urinary tract infection prevention meta analysis; D-mannose; UTI; nonantibiotic; nutraceutical; prevention; recurrent urinary tract infection; urinary tract infection.

We performed a systematic review and meta-anal. to determine whether D-mannose reduces urinary tract infection recurrence (ie, cumulative incidence) in adult women with recurrent urinary tract infection compared with other prevention agents. Secondary outcomes included side effects and compliance with D-mannose use. Ovid Medline 1946-, Embase 1947-, Scopus 1823-, Cochrane Library, Web of Science 1900-, and ClinicalTrials.gov were searched through 4/15/2020. Systematic review inclusion: randomized controlled trials, prospective cohorts, and retrospective cohorts written in English of women ≥18 years old with recurrent urinary tract infection in which D-mannose was utilized as an outpatient prevention regimen. Systematic review exclusion: lab or animal-based research, study protocols only, and conference abstracts Meta-anal. inclusion: stated D-mannose dose, follow-up time ≥6 mo, a comparison arm to D-mannose, and data available from women ≥18 years of age. Two independent reviewers made abstract, full text, and data extraction decisions. Study methodol. quality was assessed using the Cochrane Risk of Bias tool. Relative risks, confidence intervals, and heterogeneity were computed. Searches identified 776 unique citations. Eight publications met eligibility: 2 using D-mannose only; 6 using D-mannose combined with another treatment. Seven studies were prospective: 2 randomized controlled trials, 1 randomized cross-over trial, and 4 prospective cohort studies. One retrospective cohort study was included. Three studies met meta-anal. eligibility (1 randomized controlled trial, 1 randomized cross-over trial, and 1 prospective cohort). Pooled relative risk of urinary tract infection recurrence comparing D-mannose to placebo was 0.23 (95% confidence interval, 0.14-0.37; heterogeneity = 0%; D-mannose n = 125, placebo n = 123). Pooled relative risk of urinary tract infection recurrence comparing D-mannose to preventative antibiotics was 0.39 (95% confidence interval, 0.12-1.25; heterogeneity = 88%; D-mannose n = 163, antibiotics n = 163). Adverse side effects were reported in 2 studies assessing D-mannose only (1 study (n = 10) reported none; the other reported a low incidence (8/103 participants) of diarrhea). Two studies reported compliance, which was high. D-mannose appears protective for recurrent urinary tract infection (vs placebo) with possibly similar effectiveness as antibiotics. Overall, D-mannose appears well tolerated with minimal side effects-only a small percentage experiencing diarrhea. Meta-anal. interpretation must consider the small number of studies with varied study design and quality and the overall small sample size.

American Journal of Obstetrics and Gynecology published new progress about Back pain. 3458-28-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Product Details of C6H12O6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Engleder, Matthias; Mueller, Monika; Kaluzna, Iwona; Mink, Daniel; Schuermann, Martin; Leitner, Erich; Pichler, Harald; Emmerstorfer-Augustin, Anita published the artcile< Exploring Castellaniella defragrans linalool (de)hydratase-isomerase for enzymatic hydration of alkenes>, Quality Control of 78-70-6, the main research area is Castellaniella defragrans; dehydratase; geraniol; hydratase; isomerase; linalool; monoterpene hydration; myrcene; tertiary alcohol.

Acyclic monoterpenes constitute a large and highly abundant class of secondary plant metabolites and are, therefore, attractive low-cost raw materials for the chem. industry. To date, numerous biocatalysts for their transformation are known, giving access to highly sought-after monoterpenoids. In view of the high selectivity associated with many of these reactions, the demand for enzymes generating com. important target mols. is unabated. Here, linalool (de)hydratase-isomerase (Ldi, EC 4.2.1.127) from Castellaniella defragrans was examined for the regio- and stereoselective hydration of the acyclic monoterpene β-myrcene to (S)-(+)-linalool. Expression of the native enzyme in Escherichia coli allowed for identification of bottlenecks limiting enzyme activity, which were investigated by mutating selected residues implied in enzyme assembly and function. Combining these analyses with the recently published 3D structures of Ldi highlighted the precisely coordinated reduction-oxidation state of two cysteine pairs in correct oligomeric assembly and the catalytic mechanism, resp. Subcellular targeting studies upon fusion of Ldi to different signal sequences revealed the significance of periplasmic localization of the mature enzyme in the heterologous expression host. This study provides biochem. and mechanistic insight into the hydration of β-myrcene, a nonfunctionalized terpene, and emphasizes its potential for access to scarcely available but com. interesting tertiary alcs.

Molecules published new progress about 78-70-6. 78-70-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C10H18O, Quality Control of 78-70-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Davidson, Stuart C.; Gomes, Gabriel dos Passos; Kuhn, Leah R.; Alabugin, Igor V.; Kennedy, Alan R.; Tomkinson, Nicholas C. O. published the artcile< Organocatalytic sulfoxidation>, Safety of 2-(Phenylthio)ethanol, the main research area is sulfide diketone catalyst sulfoxidation kinetics; sulfoxide preparation.

Treatment of a sulfide with a catalytic amount of a 1,3-diketone in the presence of silica sulfuric acid as a co-catalyst and hydrogen peroxide (50% aq) as the stoichiometric oxidant leaded to the corresponding sulfoxide product. The reaction was effective for diaryl, aryl-alkyl and dialkyl sulfides and was tolerant of oxidisable and acid sensitive functional groups. It showed that the tris-peroxide , formed on reaction of pentane-2,4-dione with hydrogen peroxide under acidic reaction conditions, it oxidised two equivalent of sulfide using the exocyclic peroxide groups whereas the endocyclic peroxide remained intact. Calculations provided a mechanism consistent with exptl. observations and suggested the reaction proceeded via an initial acid catalyzed ring opening of a protonated tris-peroxide prior to oxygen transfer to a sulfur nucleophile.

Tetrahedron published new progress about Peroxides Role: RGT (Reagent), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Safety of 2-(Phenylthio)ethanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Song, Jianxi; Wu, Ye; Ma, Xiaojing; Feng, Lijuan; Wang, Zhiguo; Jiang, Guiquan; Tong, Haibin published the artcile< Structural characterization and α-glycosidase inhibitory activity of a novel polysaccharide fraction from Aconitum coreanum>, Application of C6H12O6, the main research area is Aconitum polysaccharide ACPP1 structure glycosidase inhibitor; A. coreanum polysaccharides (ACPP); Characterization; α-Glycosidase.

α-Glycosidase is an essential target for the management of postprandial serum glucose in diabetic patients. Therefore, the interest has been growing in the screening of α-glycosidase inhibitor from natural resource. In the present study, the structure and α-glycosidase inhibitory activity of a polysaccharide (named as ACPP-1) from Aconitum coreanum were investigated. Based on the results from high performance gel permeation chromatog., GC-MS and 1D/2D NMR spectroscopy, ACPP-1 was a highly-linear polysaccharide with a mol. weight of 34.0 kD and containing over 90% of glucose. It was composed of (1→4)-α-D-Glcp and α-Araf. ACPP-1 exhibited a dose-dependent inhibitory effect against α-glycosidase activity in vitro and the IC50 value was ∼0.8 mg/mL. In oral starch tolerance test, treatment with ACPP-1 (800 mg/kg) significantly improved the starch tolerance in mice. Taken together, this study provided a potential intervention and management for postprandial hyperglycemia by the polysaccharide fraction from A. coreanum.

Carbohydrate Polymers published new progress about Aconitum coreanum. 492-62-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Application of C6H12O6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Hong, Yawen; Ying, Tiejin published the artcile< Isolation, molecular characterization and antioxidant activity of a water-soluble polysaccharide extracted from the fruiting body of Termitornyces albuminosus (Berk.) Heim>, Category: alcohols-buliding-blocks, the main research area is Termitomyces fruiting body water soluble polysaccharide antioxidant activty; Antioxidant activity; Polysaccharide; Structure analysis; Termitornyces albuminosus.

A water-soluble polysaccharide WSP1 was extracted from the fruiting body of Termitornyces albuminosus. Its mol. weight, monosaccharide composition and mol. structure were determined by GPC, GC-MS, UV spectroscopy, FT-IR spectroscopy, methylation anal., NMR (1D and 2D) and AFM. Moreover, the antioxidant activity of WSP1 was evaluated in vitro by the tests of reducing power, scavenging ability on DPPH radical and hydroxyl radical, and chelating ability on ferrous ion. The results indicated that the mol. weight of WSP1 was 9 kDa, and it was mainly composed of fucose and galactose in a molar ratio of 1:3.09. Based on monosaccharide composition, methylation anal. and NMR, the possible repeating unit of WSP1 was presented as follows:→2-α-L-Fucp-1→ (6-α-D-Galp-1)3→. The antioxidant assay revealed that, in the concentration range tested in this experiment, WSP1 had strong scavenging ability on DPPH radical, suggesting that WSP1 could be potentially used as a powerful radical scavenger.

International Journal of Biological Macromolecules published new progress about Antioxidants. 3458-28-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Modak, Arindam; Mondal, John; Aswal, Vinod K.; Bhaumik, Asim published the artcile< A new periodic mesoporous organosilica containing diimine-phloroglucinol, Pd(II)-grafting and its excellent catalytic activity and trans-selectivity in C-C coupling reactions>, HPLC of Formula: 4396-13-8, the main research area is phloroglucinol diimine Schiff base palladium complex mesoporous silicate preparation; stereoselective heterogeneous Heck catalyst periodic mesoporous silicate phloroglucinol palladium.

A new organosilane precursor was designed via Vilsmeier-Haack formylation of phloroglucinol followed by its Schiff base condensation with (3-aminopropyl)triethoxysilane (APTES). A novel organic-inorganic hybrid periodic mesoporous organosilica (PMO) LHMS-3 containing the highly coordinating bis(propyliminomethyl)phloroglucinol moiety inside the pore wall was synthesized by using this precursor organosilane mol. Phenolic-OH and imine-N donor sites present in this PMO material were used to anchor Pd(II) species at the surface of the mesopores. Small angle neutron scattering, XRD, HR TEM, SEM, 13C and 29Si solid state MAS NMR, UV-visible and FTIR spectroscopic tools were used to characterize the 2-dimensional-hexagonal mesophase and the presence of the bis(propyliminomethyl)phloroglucinol moiety inside the pore wall. This Pd-anchored material Pd-LHMS-3 showed excellent catalytic activity and trans-selectivity in Heck C-C bond formation reactions for the synthesis of value-added aromatic and aliphatic olefins.

Journal of Materials Chemistry published new progress about Heck reaction (stereoselective). 4396-13-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H6O5, HPLC of Formula: 4396-13-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts