Tag: M.W=150-200

Meng, Xin; Che, Chengchuan; Zhang, Junming; Gong, Zhijin; Si, Meiru; Yang, Ge; Cao, Li; Liu, Jinfeng published the artcile< Structural characterization and immunomodulating activities of polysaccharides from a newly collected wild Morchella sextelata>, Computed Properties of 3458-28-4, the main research area is polysaccharide Morchella sextelata immunomodulator macrophage; Immunomodulatory; Morchella sextelata; Polysaccharides; Purification.

A purified polysaccharide was acquired from a newly collected wild Morchella. The strain identification initially showed that the strain was Morchella sextelata. This study aimed to investigate the structural features and immunomodulating activities of the polysaccharide. Polysaccharide extracted from mycelia was purified by DEAE-cellulose chromatog. and Sephadex G-25 size-exclusion chromatog. in sequence. The main fraction of polysaccharide (MSP-II) was obtained during purification process. High Performance Liquid Chromatog. (HPLC) anal. revealed that MSP-II was composed of Glc, Ara, Gal, Man, Rha, Fuc, GalUA and GluUA in ratio of 34.95:8.7:9.55:4.55:5.0:1.45:12.7:7.65. The structure of MSP-II was furtherly analyzed by FT-IR spectrum and 1 H and 13 C NMR spectroscopy, the results showed that MSP contained β glycosidic bonds as well as Α glycosidic linkages. In vitro tests proved that MSP-II could not only promote the proliferation and phagocytosis of RAW264.7 cells, but also induce the section of nitric oxide (NO) of macrophages. Consequently, the polysaccharide has a potent immunomodulatory activity by stimulating macrophages and can be considered as a novel potential immunopotentiator in medical and food industries.

International Journal of Biological Macromolecules published new progress about Cell proliferation. 3458-28-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Computed Properties of 3458-28-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Aburas, Hani; Ispirli, Humeyra; Taylan, Osman; Yilmaz, Mustafa Tahsin; Dertli, Enes published the artcile< Structural and physicochemical characterisation and antioxidant activity of an α-D-glucan produced by sourdough isolate Weissella cibaria MED17>, Product Details of C6H12O6, the main research area is Weissella sourdough alpha D glucan antioxidant activity; Antioxidant polysaccharides; Exopolysaccharides; Functional roles.

An exopolysaccharide (EPS) producer slimy-mucoid type colony was isolated from sourdough and identified as Weissella cibaria MED17. The 1H and 13C NMR spectra of EPS MED17 demonstrated that this EPS was a dextran type glucan ((1 → 6)-linked α-D-glucose core structure) containing (1 → 3)-linked α-D-glucose branches and proportion of (1 → 6)-linked α-D-glucose units to (1 → 3)-linked α-D-glucose units was 94.3:5.7%. The FTIR anal. also confirmed the (1 → 6)-linked α-D-glucose linkage. A high level of thermal stability was observed for glucan MED17 as no degradation up to 300 °C was observed by TGA and DSC anal. The XRD anal. of glucan MED17 showed its semi- crystalline nature and its compact sheet-like morphol. was observed by SEM anal. Finally, antioxidant characteristics of glucan MED17 were determined by ABTS and DPPH radical scavenging activity tests that revealed a moderate antioxidant activity of glucan MED17. These findings show potential techno-functional characteristics of glucan MED17.

International Journal of Biological Macromolecules published new progress about Exopolysaccharides Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 492-62-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Product Details of C6H12O6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yu, Juan; Ji, Haiyu; Yang, Zhizhi; Liu, Anjun published the artcile< Relationship between structural properties and antitumor activity of Astragalus polysaccharides extracted with different temperatures>, Application In Synthesis of 3458-28-4, the main research area is Astragalus polysaccharide structure antitumor temperature; Antitumor activity; Astragalus membranaceus polysaccharides; Structural characterization.

This study investigated the effects of different temperatures on structural characterization and antitumor activity of polysaccharides from Astragalus membranaceus. APS4 and APS90 were extracted at 4°C and 90°C, resp., and purified by Sephadex G-200 column. APS4-90 were obtained from APS4 after treatment at 90°C for 6 h. MTT results showed that APS4 possessed the highest inhibitory effects on MGC-803, A549 and HepG2 cells. HPGPC anal. showed that the average mol. weights of these polysaccharides were approx. 1.5 × 106 Da, while the asym. peak of APS4-90 suggested heat degradation and configuration changes of APS4. GC, NMR and methylation results showed that these three polysaccharides had similar monosaccharide components (mainly contain glucose), and their backbones were composed of (1→2)-α-D-Glcp. However, APS4 showed higher content of (1→2,6)-α-D-Glcp compared to APS4-90 and APS90, which indicated that higher branched degree would be responsible for the stronger in vitro antitumor activity in APS4. These results were also confirmed by sp. rotation and SEM anal. Our study suggested that APS4 had the potential application for cancer treatment.

International Journal of Biological Macromolecules published new progress about Antitumor agents. 3458-28-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Application In Synthesis of 3458-28-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Gan, Longzhan; Li, Xiaoguang; Zhang, Heming; Zhang, Ruoshi; Wang, Hongbin; Xu, Zhe; Peng, Biyu; Tian, Yongqiang published the artcile< Preparation, characterization and functional properties of a novel exopolysaccharide produced by the halophilic strain Halomonas saliphila LCB169T>, Electric Literature of 3458-28-4, the main research area is Halomonas exopolysaccharide mannose glucose food fermentation; Exopolysaccharide; Functional properties; Halomonas saliphila; Halophiles; Structure.

A novel exopolysaccharide, designated hsEPS, was successfully prepared from the high-salt-fermented broth of a novel species Halomonas saliphila LCB169T by ethanol precipitation, anion-exchange and gel-filtration chromatog., and its structure was well-characterized by means of chem. and spectral analyses. Results showed that hsEPS was primarily composed of mannose and glucose with a relative weight-average mol. weight of 5.133 x 104 g/mol. It was deduced that the major backbone contained (1→2)-linked α-D-Manp and (1→6)-linked α-D-Manp with branches substituted at C-2 by T-α-D-Manp and at C-6 by the fragment of T-α-D-Manp-(1→2)-α-D-Manp-(1→. A sheet-like structure was observed under high magnification. The water solubility index, water holding capacity, oil holding capacity and foaming capacity of hsEPS were 98.0, 19.3, 1386.7 and 82.2%, resp. It also exhibited outstanding emulsifying activity against all tested edible oils. Together, the resulted data indicated that hsEPS might serve as an active ingredient in food, cosmetics and detergents.

International Journal of Biological Macromolecules published new progress about Actinobacteria, halophilic. 3458-28-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Electric Literature of 3458-28-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhang, Yu-Ting; Wei, Wei; Wang, Chen; Ni, Bing-Jie published the artcile< Microbial and physicochemical responses of anaerobic hydrogen-producing granular sludge to polyethylene micro(nano)plastics>, COA of Formula: C6H12O6, the main research area is polyethylene microplastic anaerobic hydrogen producing granular sludge physicochem response; Anaerobic granular sludge; Extracellular polymeric substances; Hydrogen production; Nanoplastics; Polyethylene microplastics; Toxicity mechanism.

Micro(nano)plastics is an emerging contaminant in wastewater that has showed significant impacts on various biol. wastewater processes. Nevertheless, the underlying effects of micro(nano)plastics with different concentrations and sizes on the anaerobic hydrogen-producing granular sludge (HPG) were still unclear. This work firstly attempted to illustrate the microbial and physicochem. responses of HPG to a shock load of polyethylene microplastics (PE-MPs) with varied concentrations and sizes. The results revealed that the PE-MPs inhibitory effect on hydrogen production by HPG was both concentration- and size-dependent. Specifically, the increase of PE-MPs concentration and the decline of PE-MPs size to nano-sized plastics (NPs) significantly decreased the hydrogen yield, downgraded to 79.9 ± 2.6% and 63.0 ± 3.9% (p = 0.001, and 0.0002) of control, resp., at higher MPs concentration and the smaller MPs size (i.e., NPs). The higher PE-MPs concentration and PE-NPs also suppressed extracellular polymeric substances (EPS) generation more severely. The critical bio-processes involved in hydrogen production were disturbed by PE-MPs, with the extent of neg. impacts depending on the dosage and size of PE-MPs. These adverse impacts further manifested as granule disintegration and loss of cellular activity. Mechanism anal. highlighted the roles of oxidative stress, leachate released from PE-MPs, interaction between PE-NPs and granules inducing phys. crushing of HPG that led to possible direct contact between cells and toxic substances.

Water Research published new progress about Anaerobic fermentation. 492-62-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, COA of Formula: C6H12O6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhou, Ying; Deng, Rufang; Xu, Xinlan; Yang, Ziyin published the artcile< Enzyme Catalytic Efficiencies and Relative Gene Expression Levels of (R)-Linalool Synthase and (S)-Linalool Synthase Determine the Proportion of Linalool Enantiomers in Camellia sinensis var. sinensis>, COA of Formula: C10H18O, the main research area is linalool synthase Camellia enzyme kinetic stress; Camellia sinensis; aroma; chirality; enzyme kinetics; linalool; stresses; tea; volatile.

Linalool is abundant in tea leaves and contributes greatly to tea aroma. The two isomers of linalool, (R)-linalool and (S)-linalool, exist in tea leaves. Our study found that (R)-linalool was the minor isomer in nine of Camellia sinensis var. sinensis cultivars. The (R)-linalool synthase of tea plant CsRLIS was identified subsequently. It is a chloroplast-located protein and specifically catalyzes the formation of (R)-linalool in vitro and in vivo. CsRLIS was observed to be a stress-responsive gene and caused the accumulation of internal (R)-linalool during oolong tea manufacture, mech. wounding, and insect attack. Further study demonstrated that the catalytic efficiency of CsRLIS was much lower than that of (S)-linalool synthase CsSLIS, which might explain the lower (R)-linalool proportion in C. sinensis var. sinensis cultivars. The relative expression levels of CsRLIS and CsSLIS may also affect the (R)-linalool proportions among C. sinensis var. sinensis cultivars. This information will help us understand differential distributions of chiral aroma compounds in tea.

Journal of Agricultural and Food Chemistry published new progress about Arabidopsis. 78-70-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C10H18O, COA of Formula: C10H18O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Lu, Yuqin; Jia, Jia; Miao, Hengfeng; Ruan, Wenquan; Wang, Xinhua published the artcile< Performance improvement and biofouling mitigation in osmotic microbial fuel cells via in situ formation of silver nanoparticles on forward osmosis membrane>, Reference of 492-62-6, the main research area is silver nanoparticle biofouling mitigation forward osmosis membrane; forward osmosis; membrane fouling; osmotic microbial fuel cell; silver nanoparticle.

An osmotic microbial fuel cell (OsMFC) using a forward osmosis (FO) membrane to replace the proton exchange membrane in a typical MFC achieves superior electricity production and better effluent water quality during municipal wastewater treatment. However, inevitable FO membrane fouling, especially biofouling, has a significantly adverse impact on water flux and thus hinders the stable operation of the OsMFC. Here, we proposed a method for biofouling mitigation of the FO membrane and further improvement in current generation of the OsMFC by applying a silver nanoparticle (AgNP) modified FO membrane. The characteristic tests revealed that the AgNP modified thin film composite (TFC) polyamide FO membrane showed advanced hydrophilicity, more neg. zeta potential and better antibacterial property. The biofouling of the FO membrane in OsMFC was effectively alleviated by using the AgNP modified membrane. This phenomenon could be attributed to the changes of TFC-FO membrane properties and the antibacterial property of AgNPs on the membrane surface. An increased hydrophilicity and a more neg. zeta potential of the modified membrane enhanced the repulsion between foulants and membrane surface. In addition, AgNPs directly disturbed the functions of microorganisms deposited on the membrane surface. Owing to the biofouling mitigation of the AgNP modified membrane, the water flux and electricity generation of OsMFC were correspondingly improved.

Membranes (Basel, Switzerland) published new progress about Bacteria (colonies). 492-62-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Reference of 492-62-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhang, Liang; Castan, Andreas; Stevenson, Joanne; Chatzissavidou, Nathalie; Vilaplana, Francisco; Chotteau, Veronique published the artcile< Combined effects of glycosylation precursors and lactate on the glycoprofile of IgG produced by CHO cells>, Computed Properties of 3458-28-4, the main research area is CHO cell monoclonal antibodies IgG; Chinese hamster ovary cells (CHO cells); Glycosylation; IgG; Monoclonal antibody; Sugars; mAbs.

The glycosylation profile of therapeutic monoclonal antibodies (mAbs) is a crucial quality parameter for industrial IgG (IgG) production Several alternative carbon sources, which function as glycosylation precursors, have been reported to impact the glycosylation pattern. Since the cells give priority to glucose uptake, the presence of this substrate can lower the effects of alternative sugars on the glycosylation. In order to get a better understanding of the influence of alternative sugars on the glycosylation and to investigate how they impact each other, combinations of mannose, fructose, galactose and fucose were fed to Chinese hamster ovary (CHO) cells in batch culture when the glucose became depleted and the lactate, accumulated in the culture, was used as carbon source. Feeding with a feed containing mannose or glucose decreased by 3-7% the percentage of high mannose glycans compared to a feed without mannose or glucose. Feeding with a feed containing galactose led to 8-20% increase of monogalactoglycans (G1) glycans and 2-6% rise of digalactoglycans (G2) glycans compared to feeding without galactose or glucose. The cells fed with fucose exhibited a significantly higher concentration of intracellular GDP-Fucose. This work indicates that a feeding strategy based on non-glucose sugars and potentially lactate, could be adopted to obtain a targeted glycosylation profile.

Journal of Biotechnology published new progress about Antibodies and Immunoglobulins Role: BMF (Bioindustrial Manufacture), BIOL (Biological Study), PREP (Preparation). 3458-28-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Computed Properties of 3458-28-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Jiang, Yuan-yuan; Yu, Jun; Li, Ya-bo; Wang, Long; Hu, Liang; Zhang, Li; Zhou, Yong-hong published the artcile< Extraction and antioxidant activities of polysaccharides from roots of Arctium lappa L.>, COA of Formula: C6H12O6, the main research area is Arctium root polysaccharide ultrasonic assisted extraction antioxidant; Antioxidant activities; Arctium lappa L.; Polysaccharides; Ultrasonic-assisted extraction.

Polysaccharides were extracted from the roots of Arctium lappa L. (ALPs) using response surface methodol. with ultrasonication. A central composition design was used to optimize extraction parameters by maximizing the polysaccharide extraction yield. The modified optimal conditions were as follows: water to raw material ratio of 31 mL/g, ultrasonic power of 158 W, extraction time of 83 min, and extraction temperature of 50°C. Furthermore, fractions of ALP40-1, ALP60-1, and ALP80-1 were obtained for chem. and antioxidant activity analyses after purification Results indicated that the three fractions had a mol. weight of 218, 178, and 60 kDa, resp., and were composed of mannose, glucose, fructose, and galactose. ALP60-1 exhibited strong scavenging activities on 1,1-diphenyl-2-picryhydrazyl, hydroxyl, and superoxide radicals. These results demonstrate that ultrasonic-assisted extraction is a very effective method for extracting ALPs, and ALP60-1 is a potential novel natural antioxidant. However, further structure elucidation and in vivo experiments are required.

International Journal of Biological Macromolecules published new progress about Arctium lappa. 3458-28-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, COA of Formula: C6H12O6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Mahdian, Abolfazl; Ardakani, Mehdi Hatefi; Heydari-Bafrooei, Esmaeil; Saeednia, Samira published the artcile< Oxo-vanadium(IV) unsymmetrical Schiff base complex immobilized on γ-Fe2O3 nanoparticles: A novel and magnetically recoverable nanocatalyst for selective oxidation of sulfides and oxidative coupling of thiols>, Application In Synthesis of 699-12-7, the main research area is thioether Schiff base complex catalyst selective oxidation green chem; thiol supported oxovanadium Schiff base complex catalyst oxidative coupling; iron oxide support oxovanadium Schiff base complex preparation crystallinity.

An unsym. salen-type oxo-vanadium(IV) complex, [VO(salenac-OH)] (salenac-OH = [9-(2′,4′-dihydroxyphenyl)-5,8-diaza-4-methylnona-2,4,8-trienato](-2)), was synthesized and covalently immobilized on the surface of magnetic γ-Fe2O3 nanoparticles. The resulting γ-Fe2O3@[VO(salenac-OH)] nanoparticles were characterized by several techniques including Fourier transform IR (FT-IR) spectroscopy, X-ray diffraction (XRD), scanning and transmission electron microscopies (SEM and TEM), energy-dispersive X-ray (EDX) spectroscopy, vibrating sample magnetometry (VSM), thermal gravimetric anal. (TGA), inductively coupled plasma (ICP), and elemental anal. The prepared γ-Fe2O3@[VO(salenac-OH)] nanoparticle was utilized as an efficient catalyst for selective oxidation of sulfides to sulfoxides using 30% H2O2 as oxidant and oxidative coupling of thiols into disulfides with urea/H2O2 (UHP) as an oxidizing reagent. The products were achieved with good to excellent yields at room temperature with no over-oxidation of sulfoxides and disulfides to unexpected byproducts. This catalyst were magnetically recovered by applying an external magnet and reused for five continuous cycles in both oxidation reactions without a significant loss in its catalytic activity. Furthermore, the FT-IR spectrum and XRD pattern of the recovered catalyst showed no critical change to those of the fresh one.

Applied Organometallic Chemistry published new progress about Crystallinity. 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Application In Synthesis of 699-12-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts