Tag: M.W=150-200

Rodriguez-Flores, M. Shantal; Falcao, Soraia I.; Escuredo, Olga; Seijo, M. Carmen; Vilas-Boas, Miguel published the artcile< Description of the volatile fraction of Erica honey from the northwest of the Iberian Peninsula>, Related Products of 78-70-6, the main research area is hotrienol phenylacetaldehyde volatile Erica honey; Erica; GC–MS; Honey; Palynological analysis; SPME; VOCs.

Heather honey is highly appreciated by consumers for its sensorial profile, which varies depending on the flora used by the honeybees. Volatile compounds contribute to these qualities. Characterization of the volatile profile related to the botanical origin is of great interest for the standardization of unifloral honey. For this reason, 33 heather honey samples from northwest of the Iberian Peninsula were analyzed by headspace solid-phase microextraction (HS-SPME) to identify the key volatile compounds in this type of honey. The aim of this research was to provide a descriptive anal. of these compounds, and to find whether there is any relationship with the main Erica species. A total of 58 volatile organic compounds were found, with hotrienol, phenylacetaldehyde, and cis-linalool being the most abundant. A principal component anal. and Spearmans rank correlation showed the homogeneity of the volatile profile in the samples, and their close relationship with the main pollen types.

Food Chemistry published new progress about Erica. 78-70-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C10H18O, Related Products of 78-70-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Scott, Danielle A.; Norris-Caneda, Kim; Spruill, Laura; Bruner, Evelyn; Kono, Yuko; Angel, Peggi M.; Mehta, Anand S.; Drake, Richard R. published the artcile< Specific N-linked glycosylation patterns in areas of necrosis in tumor tissues>, Safety of (2S,3S,4R,5R)-2,3,4,5,6-Pentahydroxyhexanal, the main research area is tumor tissue necrosis glycosylation; N-linked glycans; formalin-fixed tissues; glycosylation; hypoxia; mass spectrometry imaging; necrosis.

Tissue necrosis is a form of cell death common in advanced and aggressive solid tumors, and is associated with areas of intratumoral chronic ischemia. The histopathol. of necrotic regions appear as a scaffold of cellular membrane remnants, reflective of the hypoxia and cell degradation events associated with this cellular death pathway. Changes in the glycosylation of cell surface proteins is another common feature of cancer progression. Using a recently developed mass spectrometry imaging approach to evaluate N-linked glycan distributions in human formalin-fixed clin. cancer tissues, differences in the glycan structures of regions of tumor, stroma and necrosis were evaluated. While the structural glycan classes detected in the tumor and stromal regions are typically classified as high mannose or branched glycans, the glycans found in necrotic regions displayed limited branching, contained sialic acid modifications and lack fucose modifications. While this phenomenon was initially classified in breast cancer tissues, it has been also seen in cervical, thyroid and liver cancer samples. These changes in glycosylation within the necrotic regions could provide further mechanistic insight to necrotic changes in cancer tissue and provide new research directions for identifying prognostic markers of necrosis.

International Journal of Mass Spectrometry published new progress about Cell death. 3458-28-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Safety of (2S,3S,4R,5R)-2,3,4,5,6-Pentahydroxyhexanal.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Li, Hai-Lou; Lian, Chen; Yang, Guo-Yu published the artcile< A {Ti6W4}-Cluster-Substituted Polyoxotungstate: Synthesis, Structure, and Catalytic Oxidation Properties>, Recommanded Product: 2-(Phenylthio)ethanol, the main research area is methylammonium titanium tungstoantimonate cluster preparation crystal mol structure catalyst; oxidation catalyst methylammonium titanium tungstoantimonate cluster preparation.

A novel Ti-W-oxo-cluster substituted tungstoantimonate (TA) [H2N(CH3)2]3Na4H9[{Ti6W4O18(OH)(H2O)3}(B-α-SbW9O33)3]•20H2O (1) has been made by hydrothermal reactions of trivacant [B-α-SbW9O33]9- units, Ti4+ cations and WO42- anions in the presence of [H2N(CH3)2]•Cl and structurally characterized. Intriguingly, the polyoxoanion of 1 is constructed from three [B-α-SbW9O33]9- units and a previously unobserved decanuclear heterometallic Ti-W-oxo-cluster [Ti6W4O18(OH)(H2O)3]11+ {Ti6W4} that is comprised of an octahedral [Ti6WO6(H2O)3]18+ cluster and an edge-sharing [W3O12(OH)]7- fragment via six W-O-Ti/W linkers. Furthermore, studies on the catalytic oxidation properties reveal that 1 possesses good catalytic activity toward the oxidation reactions of various sulfides and cyclooctene basing on the environmentally friendly oxidant H2O2.

Inorganic Chemistry published new progress about Crystal structure. 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Recommanded Product: 2-(Phenylthio)ethanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wang, Yue-Lin; Zhang, Zhong; Li, Hai-Lou; Li, Xu-Yan; Yang, Guo-Yu published the artcile< An Oxalate-Functionalized Tetra-ZrIV-Substituted Sandwich-Type Silicotungstate: Hydrothermal Synthesis, Structural Characterization, and Catalytic Oxidation of Thioethers>, Product Details of C8H10OS, the main research area is thioether oxidation zirconium silicotungstate POM catalyst; sulfoxide preparation zirconium silicotungstate POM catalyst; crystal structure zirconium silicotungstate POM preparation.

A previously unknown inorganic-organic hybrid polyoxidometalate constructed from oxalate-functionalized tetra-ZrIV-substituted dimeric silicotungstate, (NH4)3Na5K6[Zr4(μ3-O)2(μ-OH)2(ox)2(SiW10O37)2]·23H2O (1, ox = oxalate) has been synthesized under mild hydrothermal conditions and characterized by FTIR spectroscopy, elemental anal., TGA, single-crystal and powder x-ray diffraction. Compound 1 contains a centrosym. polyoxidoanion structure with two [SiW10O37]10- units sandwiching a [Zr4(μ3-O)2(μ-OH)2(ox)2]6+ cluster. The catalytic performances of 1 involving oxygenation reactions of thioethers by H2O2 were evaluated, showing that 1 is an excellent catalyst for the catalytic oxidation of thioethers to sulfoxides/sulfones.

European Journal of Inorganic Chemistry published new progress about Crystal structure. 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Product Details of C8H10OS.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Xie, Fan; Seifert, Nathan A.; Heger, Matthias; Thomas, Javix; Jager, Wolfgang; Xu, Yunjie published the artcile< The rich conformational landscape of perillyl alcohol revealed by broadband rotational spectroscopy and theoretical modelling>, Recommanded Product: (S)-(4-(Prop-1-en-2-yl)cyclohex-1-en-1-yl)methanol, the main research area is perillyl alc conformer conformation internal rotation rotational spectra.

The rotational spectrum of perillyl alc., a naturally occurring, chiral, dietary monoterpene, was investigated using a chirped pulse Fourier transform microwave spectrometer and a cavity-based Fourier transform microwave spectrometer. To aid the assignment of the dense chirped pulse spectrum obtained, extensive theor. conformational searches were carried out. In one approach, several one and two-dimensional scans along three dihedral angles associated with the rotational motions of the -OH, -CH2OH, and -C(CH2)CH3 groups were performed. These scans, combined with the equatorial and axial positions of the -C(CH2)CH3 group, resulted in 54 conformers. The same conformers were identified in the second approach where a semi-classical conformational search code was used. The relative stabilities of the conformers and the interconversion barriers among them were explored extensively at the DFT B3LYP-D3(BJ)/def2-TZVP and B3LYP-D3(BJ)/6-311++G(2d,p), as well as local MP2/aug-cc-pVQZ levels of theory, and 12 conformers were ultimately identified as possibly observable candidates in a mol. jet expansion. Rotational spectra of eight out of the 12 candidates were observed exptl. and analyzed. The non-observation of the remaining four conformers may be attributed to their low abundances. The study points out the importance of identifying all conformers of relevant abundance, even those which could not be detected exptl., in order to properly benchmark the theor. relative stabilities with the exptl. ones. A comprehensive study of the conformational distribution of perillyl alc. contributes to our understanding of its structural properties which may influence its functions.

Physical Chemistry Chemical Physics published new progress about Conformation. 18457-55-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C10H16O, Recommanded Product: (S)-(4-(Prop-1-en-2-yl)cyclohex-1-en-1-yl)methanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yuan, Qin; Lin, Shang; Fu, Yuan; Nie, Xi-Rui; Liu, Wen; Su, Yan; Han, Qiao-Hong; Zhao, Li; Zhang, Qing; Lin, De-Rong; Qin, Wen; Wu, Ding-Tao published the artcile< Effects of extraction methods on the physicochemical characteristics and biological activities of polysaccharides from okra (Abelmoschus esculentus)>, Related Products of 3458-28-4, the main research area is Abelmoschus hot water extraction physicochem antioxidant polysaccharide; Antioxidant activity; Binding properties; Enzyme inhibition; Extraction method; Okra polysaccharides.

The impacts of three extraction techniques, including hot water extraction (HWE), pressurized water extraction (PWE), and microwave assisted extraction (MAE), on the physicochem. characteristics, antioxidant activities, in vitro binding properties, and in vitro inhibitory activities on α-amylase and α-glucosidase of okra polysaccharides (OPPs) were investigated and compared. The extraction yields, constituent monosaccharides, and FT-IR spectra of OPP-W, OPP-P, and OPP-M extracted by HWE, PWE, and MAE, resp., were similar. However, their mol. weights, intrinsic viscosities, uronic acids, and degree of esterification were different. Furthermore, results showed that OPP-W, OPP-P, and OPP-M exhibited remarkable antioxidant activities, binding capacities, and inhibitory activities on α-amylase and α-glucosidase. Indeed, the antioxidant activities of OPP-W were significantly lower than those of OPP-M and OPP-P, which might be attributed to the low mol. weights and high contents of unmethylated galacturonic acid of OPP-P and OPP-M. However, the binding capacities and inhibitory activities on α-amylase and α-glucosidase of OPP-W and OPP-P were similar, but significantly higher than those of OPP-M, which might be attributed to the low mol. weights of OPP-M. Results suggested that the PWE method could be a good potential technique for the extraction of OPPs with high bioactivities for industrial applications.

International Journal of Biological Macromolecules published new progress about Abelmoschus esculentus. 3458-28-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Related Products of 3458-28-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Saikia, Gangutri; Ahmed, Kabirun; Rajkhowa, Chandrasee; Sharma, Mitu; Talukdar, Hiya; Islam, Nashreen S. published the artcile< Polymer immobilized tantalum(V)-amino acid complexes as selective and recyclable heterogeneous catalysts for oxidation of olefins and sulfides with aqueous H2O2>, Category: alcohols-buliding-blocks, the main research area is olefin tantalum amino acid heterogeneous catalyst chemoselective oxidation green; epoxide preparation; sulfide tantalum amino acid heterogeneous catalyst chemoselective oxidation green; sulfoxide preparation.

Polymer supported heterogeneous peroxotantalum(V) catalysts were prepared by anchoring Ta(V)-diperoxo species to chloromethylated poly(styrene-divinylbenzene) resin functionalized with amino acids asparagine (L-Asn) and arginine (L-Arg). The structurally well-defined catalysts, [Ta(O2)2(L)2]–MR, [L = asparagine (catalyst 1) or arginine (catalyst 2) and MR = Merrifield resin], were comprehensively characterized by elemental anal. (CHN, ICP-OES, energy dispersive X-ray spectroscopy), spectral studies (FT-IR, Raman, 13C NMR, diffuse reflectance UV-vis and XPS), SEM, XRD, Brunauer-Emmett-Teller (BET) and thermogravimetric anal. (TGA). The supported peroxotantalum (pTa) compounds displayed excellent catalytic performance in epoxidation of alkenes with 30% H2O2, under solvent free reaction conditions. Styrene was epoxidized with >99% selectivity with the highest TOF of 1040 h-1 obtained within 30 min reaction time, whereas the TOF for norbornene epoxidation was 2000 h-1 within 1 h with >95% epoxide selectivity. Furthermore, the immobilized catalysts facilitated chemoselective oxidation of a broad range of organic sulfides to the desired sulfoxides with H2O2 in methanol, under mild reaction conditions. The oxidations proceeded with a high H2O2 efficiency percentage and are amenable to ready scalability. The heterogeneous catalysts could be easily recovered and reused for several consecutive catalytic cycles with undiminished activity/selectivity profiles in all cases. The developed catalytic strategies are operationally simple and, being free from halogenated solvent or any other toxic auxiliaries, environmentally clean.

New Journal of Chemistry published new progress about Alkenes Role: RCT (Reactant), RACT (Reactant or Reagent). 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kashiwadani, Hideki; Higa, Yurina; Sugimura, Mitsutaka; Kuwaki, Tomoyuki published the artcile< Linalool odor-induced analgesia is triggered by transient receptor potential ankyrin 1-independent pathway in mice>, Electric Literature of 78-70-6, the main research area is linalool odor analgesia transient receptor potential ankyrin 1; Analgesia; Linalool; TRPA1; TRPA1-deficient mice; TRPA1-selective antagonist.

Abstract: We had recently reported that linalool odor exposure induced significant analgesic effects in mice and that the effects were disappeared in olfactory-deprived mice in which the olfactory epithelium was damaged, thus indicating that the effects were triggered by chemial senses evoked by linalool odor exposure. However, the peripheral neuronal mechanisms, including linalool receptors that contribute toward triggering the linalool odor-induced analgesia, still remain unexplored. In vitro studies have shown that the transient receptor potential ankyrin 1 (TRPA1) responded to linalool, thus raising the possibility that TRPA1 expressed on the trigeminal nerve terminal detects linalool odor inhaled into the nostril and triggers the analgesic effects. To address this hypothesis, we measured the behavioral pain threshold for noxious mech. stimulation in TRPA1-deficient mice. In contrast to our expectation, we found a significant increase in the threshold after linalool odor exposure in TRPA1-deficient mice, indicating the analgesic effects of linalool odor even in TRPA1-deficient mice. Furthermore, intranasal application of TRPA1 selective antagonist did not alter the analgesic effect of linalool odor. These results showed that the linalool odor-induced analgesia was triggered by a TRPA1-independent pathway in mice.

Behavioral and Brain Functions published new progress about Analgesia. 78-70-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C10H18O, Electric Literature of 78-70-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Meng, Zhiyuan; Tian, Sinuo; Sun, Wei; Liu, Li; Yan, Sen; Huang, Shiran; Zhu, Wentao; Zhou, Zhiqiang published the artcile< Effects of exposure to prothioconazole and its metabolite prothioconazole-desthio on oxidative stress and metabolic profiles of liver and kidney tissues in male mice>, Related Products of 492-62-6, the main research area is prothioonazole fungiide metabolic disorder oxidative stress kidney; Metabolic profile; Oxidative stress; Prothioconazole; Prothioconazole-desthio.

Prothioconazole (PTC), a popular agricultural fungicide, and its main metabolite prothioconazole-desthio (PTCd) are receiving great attention due to their toxicol. effects in the non-target organisms. This study investigated their dosage-dependent (1 and 5 mg/kg BW/day) toxicol. effects on oxidative stress and metabolic profiles of liver and kidney tissues using male mice. PTC and PTCd significantly inhibited the growth phenotype including body weights gain, liver and kidney indexes. Furthermore, these effects were deeply investigated using the biomarkers of oxidative stress, and metabolomics. Notably, these effects were dose and tissue-dependent. Specifically, the more serious impacts involving oxidative stress and metabolic disorders were observed in the high concentration treatment groups. Also, the liver tissue was more severely affected than the kidney tissue. Lastly, the change in oxidative stress biomarkers and metabolomics profile revealed that PTCd induced more severe toxic effects than the parent compound PTC. In brief, these results indicate that exposure to PTC and PTCd could cause potential health risks in mammals.

Environmental Pollution (Oxford, United Kingdom) published new progress about Biomarkers. 492-62-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Related Products of 492-62-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wang, Yongqiang; Xie, Hongbing; Liu, Dongyang; Wang, Yimin; Liu, Changzhong; Khan, Muhammad Akram; Jiang, Jinqing; Zhang, Wenjv published the artcile< Effects of Different Sample Pulverisation Methods on the Extraction of Metabolites from the Fermented Cottonseed Meal Based on UPLC-Q-TOF-MS>, Name: (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol, the main research area is Lactobacillus cottonseed meal fermented feed pulverization food processing UPLC.

Abstract: The precondition of studying biol. sample is to extract sample metabolites by the best pretreatment methods. There is already limited information about pretreatments of fermented feed metabolites. The study compared the extraction effects of different pulverisation methods used in the sample pretreatment process for the extraction of metabolites from cottonseed meal fermented by Lactobacillus acidophilus based on UPLC-Q-TOF-MS. The extraction effects of three pretreatments (non-pulverisation (WF), pulverisation (F), and high-speed homogenisation methods (YJ)) were compared with the numbers of metabolites and the normalized peak areas of the metabolites. The results showed that the number of metabolites extracted with three pulverisation methods were 1745, 1896, 2132 (ESI+ mode) and 1447, 1675, 2073 (ESI- mode), resp. The number of variable importance plot (VIP) metabolites and the relative peak areas of metabolites showed that the trend was YJ > F > WF. The extraction effect of high-speed homogenisation method was the best way to extract metabolites from the fermented cottonseed meal. This study built a foundation work for the further research of the fermented feed metabolomics.

Current Microbiology published new progress about Cottonseed meal. 492-62-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Name: (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts