Tag: M.W=150-200

Guo, Fengyu; Liang, Qiong; Zhang, Ming; Chen, Wenxue; Chen, Haiming; Yun, Yonghuan; Zhong, Qiuping; Chen, Weijun published the artcile< Antibacterial activity and mechanism of linalool against Shewanella putrefaciens>, Computed Properties of 78-70-6, the main research area is Shewanella putrefaciens; antibacterial mechanism; linalool; metabolomics.

The demand for reduced chem. preservative usage is currently growing, and natural preservatives are being developed to protect seafood. With its excellent antibacterial properties, linalool has been utilized widely in industries. However, its antibacterial mechanisms remain poorly studied. Here, untargeted metabolomics was applied to explore the mechanism of Shewanella putrefaciens cells treated with linalool. Results showed that linalool exhibited remarkable antibacterial activity against S. putrefaciens, with 1.5 μL/mL min. inhibitory concentration (MIC). The growth of S. putrefaciens was suppressed completely at 1/2 MIC and 1 MIC levels. Linalool treatment reduced the membrane potential (MP); caused the leakage of alk. phosphatase (AKP); and released the DNA, RNA, and proteins of S. putrefaciens, thus destroying the cell structure and expelling the cytoplasmic content. A total of 170 differential metabolites (DMs) were screened using metabolomics anal., among which 81 species were upregulated and 89 species were downregulated after linalool treatment. These DMs are closely related to the tricarboxylic acid (TCA) cycle, glycolysis, amino acid metabolism, pantothenate and CoA biosynthesis, aminoacyl-tRNA biosynthesis, and glycerophospholipid metabolism In addition, linalool substantially affected the activity of key enzymes, such as succinate dehydrogenase (SDH), pyruvate kinase (PK), ATPase, and respiratory chain dehydrogenase. The results provided some insights into the antibacterial mechanism of linalool against S. putrefaciens and are important for the development and application of linalool in seafood preservation.

Molecules published new progress about 78-70-6. 78-70-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C10H18O, Computed Properties of 78-70-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Nikoorazm, Mohsen; Rezaei, Ziba; Tahmasbi, Bahman published the artcile< Two Schiff-base complexes of copper and zirconium oxide supported on mesoporous MCM-41 as an organic-inorganic hybrid catalysts in the chemo and homoselective oxidation of sulfides and synthesis of tetrazoles>, Product Details of C8H10OS, the main research area is Schiff base metal complex supported mesoporous MCM41 catalyst preparation; tetrazole green preparation; nitrile sodium azide cycloaddition Schiff base metal complex catalyst; sulfoxide green preparation chemoselective homoselective; sulfide oxidation Schiff base metal complex catalyst.

A simple and efficient procedure was reported for the synthesis of tetrazole derivatives I [R = CH2CN, Ph, 4-BrC6H4, etc.], the chemo and homoselective oxidation of sulfides to sulfoxides R1S(O)R2 [R1 = allyl, n-Bu, Ph, etc.; R2 = Me, CH2CH2OH, Bn, etc.] in the presence of two Schiff-base complexes of zirconium oxide and copper anchored on MCM-41 as mesoporous and organometallic catalysts under green conditions. All the products were obtained in excellent yields with high TOF values indicating the high activity of the synthesized catalysts. These catalysts were characterized by XRD, TGA, SEM, EDS, FT-IR, TEM, WDX, BET and AAS techniques and could be recycled for several times without significant loss in catalytic activity. The recovered catalysts were characterized by SEM, FT-IR and AAS anal. which shown an excellent agreement with fresh catalysts.

Journal of Porous Materials published new progress about [3+2] Cycloaddition reaction. 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Product Details of C8H10OS.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wang, Huajie; Hua, Jinjie; Jiang, Yongwen; Yang, Yanqin; Wang, Jinjin; Yuan, Haibo published the artcile< Influence of fixation methods on the chestnut-like aroma of green tea and dynamics of key aroma substances>, Computed Properties of 78-70-6, the main research area is green teachestnut aroma fixation method; Electromagnetic roller-hot air–steam triple fixation; Gas chromatography-tandem mass spectrometry (GC–MS); Infrared-assisted headspace coupled to solid-phase microextraction; Multiple experiment viewer (MEV); Odor activity value (OAV); Partial least-squares discriminant analysis (PLS-DA).

Fixation is the key process to ensure green tea quality; however, the effect of various fixation methods on the formation of green tea with a chestnut-like aroma and the evolution of key volatile compounds has not been assessed to date. In this study, we compared four types of fixation methods for green tea: roller-hot air-steam, roller-hot air, roller-steam, and single roller. IR-assisted headspace solid-phase microextraction and gas chromatog.-tandem dual mass spectrometry technol. were used to detect the volatile compounds of green tea samples during processing. Partial least-squares discriminant anal. (PLS-DA), multiple experiment viewer (MEV), odor activity value (OAV), and least-significant difference analyzes were then applied to clarify the best fixation method for forming a chestnut-like aroma and associated compounds, and to explore the change law of key volatile compounds using different green tea fixation processes. One hundred and eighty-four volatile compounds were detected in the processed samples, with roller-hot air fixation found as the optimal method for generating an intense and long-lasting chestnut-like aroma and floral taste, based on sensory evaluation. The PLS-DA model clearly distinguished the four kinds of fixation samples and obtained 32 differential volatile compounds Combining OAVs with screening by MEV anal., 2,6,10,10-tetramethyl-1-oxaspiro [4.5] dec-6-ene, linalool, cedrol, 3-methyl-butanal, trans-β-ionone, and τ-cadinol emerged as key differential volatile compounds between green teas with and without a chestnut-like aroma. The evolution of these six differential volatile compounds throughout the tea-making process confirmed that rolling-hot air coupling treatment is most conducive to produce a chestnut-like aroma, which is beneficial to form and transform 2,6,10,10-tetramethyl-1-oxaspiro[4.5] dec-6-ene, 3-methyl-butanal, and τ-cadinol with baking aromas and fruity substances. These results provide a theor. basis and tech. guidance for the precise and directional processing of high-quality green tea with a chestnut-like aroma.

Food Research International published new progress about Alcohols Role: FFD (Food or Feed Use), BIOL (Biological Study), USES (Uses). 78-70-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C10H18O, Computed Properties of 78-70-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wheatley, David E.; Fontenelle, Clement Q.; Kuppala, Ramakrishna; Szpera, Robert; Briggs, Edward L.; Vendeville, Jean-Baptiste; Wells, Neil J.; Light, Mark E.; Linclau, Bruno published the artcile< Synthesis and Structural Characteristics of all Mono- and Difluorinated 4,6-Dideoxy-D-xylo-hexopyranoses>, Category: alcohols-buliding-blocks, the main research area is monosaccharide crystal structure free energy human deoxygenation deoxyfluorination; crystal structure free energy deoxyxylohexopyranose glycoside preparation protecting group.

Here, we report a detailed study on the synthesis of monosaccharides in which the hydroxy groups at their 4- and 6-positions are replaced by all possible mono- and difluorinated motifs. Minimization of protecting group use was a key aim. It was found that introducing electroneg. substituents, either as protecting groups or as deoxygenation intermediates, was generally beneficial for increasing deoxyfluorination yields. A detailed structural study of this set of analogs demonstrated that dideoxygenation/fluorination at the 4,6-positions caused very little distortion both in the solid state and in aqueous solution Unexpected trends in α/β anomeric ratios were identified. Increasing fluorine content always increased the α/β ratio, with very little difference between regio- or stereoisomers, except when 4,6-difluorinated.

Journal of Organic Chemistry published new progress about Crystal structure. 492-62-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Soboleva, Oxana A.; Protsenko, Pavel V.; Korolev, Vadim V.; Viktorova, Jekaterina; Yakushenko, Alexey; Kudla, Ruth; Gutmann, Jochen S.; Tsarkova, Larisa A. published the artcile< Aroma Molecules as Dynamic Volatile Surfactants: Functionality beyond the Scent>, Related Products of 78-70-6, the main research area is aroma mol dynamics surfactant volatile interfacial; dynamic surface tension; essential oils; ink-jet printing; terpens; volatile surfactants; wetting.

Understanding of nonequilibrium processes at dynamic interfaces is indispensable for advancing design and fabrication of solid-state and soft materials. The research presented here unveils specific interfacial behavior of aroma mols. and justifies their usage as multifunctional volatile surfactants. As nonconventional volatile amphiphiles, we study com. available poorly water-soluble compounds from the classes of synthetic and essential flavor oils. Their disclosed distinctive feature is a high dynamic interfacial activity, so that they decrease the surface tension of aqueous solutions on a time scale of milliseconds. Another potentially useful property of such amphiphiles is their volatility, so that they notably evaporate from interfaces on a time scale of seconds. This behavior allows for control of wetting and spreading processes. A revealed synergetic interfacial behavior of mixtures of conventional and volatile surfactants is attributed to a decrease of the activation barrier as a result of high statistical availability of new sites at the surface upon evaporation of the volatile component. Our results offer promising advantages in manufacturing technologies which involve newly creating interfaces, such as spraying, coating technologies, ink-jet printing, microfluidics, laundry, and stabilization of emulsions in cosmetic and food industry, as well as in geosciences for controlling aerosol formation.

ACS Applied Materials & Interfaces published new progress about Aerosols. 78-70-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C10H18O, Related Products of 78-70-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Tamoradi, Taiebeh; Ghadermazi, Mohammad; Ghorbani-Choghamarani, Arash published the artcile< Highly efficient, green, rapid, and chemoselective oxidation of sulfur-containing compounds in the presence of an MCM-41@creatinine@M (M = La and Pr) mesostructured catalyst under neat conditions>, Related Products of 699-12-7, the main research area is sulfide thiol oxidation catalyst preparation MCM41 creatinine lanthanum praseodymium.

The authors report the synthesis of two green recoverable catalysts by covalent linking of the creatinine La and Pr complexes on an MCM-41 mesostructure with the com. available materials and via a simple and inexpensive procedure. These heterogeneous catalysts were characterized by FTIR spectroscopy, energy-dispersive x-ray spectroscopy, SEM, N2 adsorption and desorption, inductively coupled plasma optical emission spectroscopy, and TGA. The obtained mesostructures act as active and reusable catalysts for the oxidation of sulfides and oxidative coupling of thiols under neat conditions. More importantly, significant practical advantages of this environmentally friendly process include high efficiency, good reaction times, and convenient recovery and reusability for several times without any significant loss of activity of the catalyst.

New Journal of Chemistry published new progress about Energy-dispersive x-ray spectroscopy. 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Related Products of 699-12-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Jabir, Majid S.; Taha, Ali A.; Sahib, Usama I.; Taqi, Zainab J.; Al-Shammari, Ahmed M.; Salman, Alya S. published the artcile< Novel of nano delivery system for Linalool loaded on gold nanoparticles conjugated with CALNN peptide for application in drug uptake and induction of cell death on breast cancer cell line>, Name: 3,7-Dimethylocta-1,6-dien-3-ol, the main research area is breast cancer linalool gold nanoparticle CALNN peptide anticancer; Antioxidant activity; CALNN; Cellular uptake; Cytotoxicity; FTIC; Gold nanoparticles; Linalool; MCF-7.

Linalool is a monoterpene alc. which occurs naturally in several aromatic plants. The aims of this study are to load Linalool on gold nanoparticles, conjugate the complex with CALNN peptide, and investigate them for in-vitro anticancer activities against breast cancer (MCF-7) cell line. Linalool was obtained with 98% purity while gold nanoparticles and CALNN peptide were chem. synthesized. The formation of LIN-GNPs and LIN-GNPs-CALNN was observed through a color change. These compounds were confirmed and characterized using SEM, DLS, AFM, UV-VIS spectrophotometer, XRD, and FTIR. The free radical scavenging potential of each compound was confirmed based on its stable antioxidant effects using different parameters. Blood compatibility on red blood cells was confirmed by hemolytic and in vitro cytotoxicity assays. The in-vitro anticancer activity of each compound towardMCF-7 cell line was investigated using various parameters. From the results, Linalool, GNPs, LIN-GNPs, and LIN-GNPs-CALNN were found to exert cell growth arrest against MCF-7 cell line. The anti-proliferative effect of these compounds was due to cell death and induction of apoptosis confirmed using acridine orange-Ethidium bromide dual staining, DAPI staining, and electrophoresis anal. of DNA fragmentation. High fluorescent signals specific for the cellular uptake of LIN-GNPs and LIN-GNPs-CALNN into the cytoplasm of the cell line were confirmed. To study the toxicity of LIN-GNPs-CALNN in animal models, the hematol., histopathol., and body weight changes were estimated after 4 wk of i.p. injection of the compounds into the animal models. Our results demonstrate that Linalool, GNPs, Linalool-GNPs, and Linalool-GNPs-CALNN peptide had no side effects and could be clin. used for future therapeutic purposes.

Materials Science & Engineering, C: Materials for Biological Applications published new progress about Antioxidants. 78-70-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C10H18O, Name: 3,7-Dimethylocta-1,6-dien-3-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Rodriguez-Flores, M. Shantal; Falcao, Soraia I.; Escuredo, Olga; Seijo, M. Carmen; Vilas-Boas, Miguel published the artcile< Description of the volatile fraction of Erica honey from the northwest of the Iberian Peninsula>, Related Products of 78-70-6, the main research area is hotrienol phenylacetaldehyde volatile Erica honey; Erica; GC–MS; Honey; Palynological analysis; SPME; VOCs.

Heather honey is highly appreciated by consumers for its sensorial profile, which varies depending on the flora used by the honeybees. Volatile compounds contribute to these qualities. Characterization of the volatile profile related to the botanical origin is of great interest for the standardization of unifloral honey. For this reason, 33 heather honey samples from northwest of the Iberian Peninsula were analyzed by headspace solid-phase microextraction (HS-SPME) to identify the key volatile compounds in this type of honey. The aim of this research was to provide a descriptive anal. of these compounds, and to find whether there is any relationship with the main Erica species. A total of 58 volatile organic compounds were found, with hotrienol, phenylacetaldehyde, and cis-linalool being the most abundant. A principal component anal. and Spearmans rank correlation showed the homogeneity of the volatile profile in the samples, and their close relationship with the main pollen types.

Food Chemistry published new progress about Erica. 78-70-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C10H18O, Related Products of 78-70-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Tamoradi, Taiebeh; Ghadermazi, Mohammad; Ghorbani-Choghamarani, Arash published the artcile< Highly efficient, green, rapid, and chemoselective oxidation of sulfur-containing compounds in the presence of an MCM-41@creatinine@M (M = La and Pr) mesostructured catalyst under neat conditions>, Related Products of 699-12-7, the main research area is sulfide thiol oxidation catalyst preparation MCM41 creatinine lanthanum praseodymium.

The authors report the synthesis of two green recoverable catalysts by covalent linking of the creatinine La and Pr complexes on an MCM-41 mesostructure with the com. available materials and via a simple and inexpensive procedure. These heterogeneous catalysts were characterized by FTIR spectroscopy, energy-dispersive x-ray spectroscopy, SEM, N2 adsorption and desorption, inductively coupled plasma optical emission spectroscopy, and TGA. The obtained mesostructures act as active and reusable catalysts for the oxidation of sulfides and oxidative coupling of thiols under neat conditions. More importantly, significant practical advantages of this environmentally friendly process include high efficiency, good reaction times, and convenient recovery and reusability for several times without any significant loss of activity of the catalyst.

New Journal of Chemistry published new progress about Energy-dispersive x-ray spectroscopy. 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Related Products of 699-12-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Jabir, Majid S.; Taha, Ali A.; Sahib, Usama I.; Taqi, Zainab J.; Al-Shammari, Ahmed M.; Salman, Alya S. published the artcile< Novel of nano delivery system for Linalool loaded on gold nanoparticles conjugated with CALNN peptide for application in drug uptake and induction of cell death on breast cancer cell line>, Name: 3,7-Dimethylocta-1,6-dien-3-ol, the main research area is breast cancer linalool gold nanoparticle CALNN peptide anticancer; Antioxidant activity; CALNN; Cellular uptake; Cytotoxicity; FTIC; Gold nanoparticles; Linalool; MCF-7.

Linalool is a monoterpene alc. which occurs naturally in several aromatic plants. The aims of this study are to load Linalool on gold nanoparticles, conjugate the complex with CALNN peptide, and investigate them for in-vitro anticancer activities against breast cancer (MCF-7) cell line. Linalool was obtained with 98% purity while gold nanoparticles and CALNN peptide were chem. synthesized. The formation of LIN-GNPs and LIN-GNPs-CALNN was observed through a color change. These compounds were confirmed and characterized using SEM, DLS, AFM, UV-VIS spectrophotometer, XRD, and FTIR. The free radical scavenging potential of each compound was confirmed based on its stable antioxidant effects using different parameters. Blood compatibility on red blood cells was confirmed by hemolytic and in vitro cytotoxicity assays. The in-vitro anticancer activity of each compound towardMCF-7 cell line was investigated using various parameters. From the results, Linalool, GNPs, LIN-GNPs, and LIN-GNPs-CALNN were found to exert cell growth arrest against MCF-7 cell line. The anti-proliferative effect of these compounds was due to cell death and induction of apoptosis confirmed using acridine orange-Ethidium bromide dual staining, DAPI staining, and electrophoresis anal. of DNA fragmentation. High fluorescent signals specific for the cellular uptake of LIN-GNPs and LIN-GNPs-CALNN into the cytoplasm of the cell line were confirmed. To study the toxicity of LIN-GNPs-CALNN in animal models, the hematol., histopathol., and body weight changes were estimated after 4 wk of i.p. injection of the compounds into the animal models. Our results demonstrate that Linalool, GNPs, Linalool-GNPs, and Linalool-GNPs-CALNN peptide had no side effects and could be clin. used for future therapeutic purposes.

Materials Science & Engineering, C: Materials for Biological Applications published new progress about Antioxidants. 78-70-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C10H18O, Name: 3,7-Dimethylocta-1,6-dien-3-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts