Tag: M.W=150-200

Katagiri, Ryo; Uekusa, Yoshinori; Narukawa, Yuji; Kiuchi, Fumiyuki published the artcile< Synthesis of Methylophiopogonanone A>, SDS of cas: 4396-13-8, the main research area is methylophiopogonanone A preparation.

Here, methylophiopogonanone A I was synthesized, which was a candidate marker compound for identification test of Ophiopogon Root, from phloroglucinol in 9 steps with overall yield of 11.1%.

Heterocycles published new progress about Acylation. 4396-13-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H6O5, SDS of cas: 4396-13-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zeng, Ying-Jie; Yang, Hui-Rong; Wang, Hong-Feng; Zong, Min-Hua; Lou, Wen-Yong published the artcile< Immune enhancement activity of a novel polysaccharide produced by Dendrobium officinale endophytic fungus Fusarium solani DO7>, Name: (2S,3S,4R,5R)-2,3,4,5,6-Pentahydroxyhexanal, the main research area is polysaccharide Dendrobium Fusarium immunomodulatory activity.

A novel polysaccharide DG2 was obtained from the Dendrobium officinale endophytic fungus Fusarium solani DO7. The structural characterization and immunol. activity of DG2 were investigated. Results showed that DG2 with the mol. weight of 152.8 kDa was composed of Galp, Manp, Glcp and Araf at a molar ratio of 4.3:1.9:2.8: 1.0. The main linkage types of DG2 were (1 → )-β-D-Glc, (1 → 4)-β-D-Glc, (1 → 3,6)-β-D-Gal and (1 → 6)-β-D-Gal, which demonstrated DG2 was a novel galactoglucan and different from other fungal and botanic polysaccharide. Furthermore, DG2 did not contain deoxynivalenol, and showed no direct toxicity to human embryonic kidney cells and RAW 264.7 cells. Meanwhile, DG2 could increase the TNF-α, IL-6 and iNOs mRNA expression levels of RAW264.7 cells, and further promote the production of TNF-α, IL-6 and NO. These results suggested DG2 could enhance macrophage-mediated immune responses and have the potential to be an attractive functional food supplement candidate for the hypoimmunity therapies.

Journal of Functional Foods published new progress about Dendrobium catenatum. 3458-28-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Name: (2S,3S,4R,5R)-2,3,4,5,6-Pentahydroxyhexanal.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Lian, Shengyang; Fan, Shuling; Yang, Ying; Yu, Bin; Dai, Chunxiao; Qu, Yuanyuan published the artcile< Selenium nanoparticles with photocatalytic properties synthesized by residual activated sludge>, Computed Properties of 492-62-6, the main research area is dye selenite selenium nanoparticle photocatalyst activated sludge wastewater treatment; Activated sludge; Biosynthesis; Photocatalysis; Rhodamine B; Selenium nanoparticles.

The treatment and disposal of residual activated sludge is a worldwide problem and the research on its reuse is still only in the earliest stages. Selenite is a toxic pollutant, while selenium nanoparticles (SeNPs) are environmentally friendly and have promising application prospects. At present, the reduction mechanism of selenite under the complex system is still poorly understood. In order to explore the mechanism of SeNPs synthesis by activated sludge resource utilization, SeNPs were synthesized by activated sludge extracts of domestic sewage (DSeNPs) and coking sewage (CSeNPs), resp. The synthesis process, zeta potential and morphol. size of SeNPs were changed by pH value, extract concentration and extract composition Under the same synthesis conditions, the morphologies of DSeNPs and CSeNPs were mainly spherical and pseudo-spherical, while CSeNPs also contained pseudo-rod shape particles. The sizes and crystal grains of CSeNPs were smaller than those of DSeNPs. Compared with DSeNPs, a specific protein (∼35 kDa) was found on the surface of CSeNPs using SDS-PAGE. By analyzing the fluorescence images of the two SeNPs, it was found that the relative contents of proteins, α-D-glucopyranose polysaccharides, and β-D-glucopyranose polysaccharides on their surfaces were obviously different (P < 0.05). The present study demonstrated that proteins, polysaccharides, humic-like and fulvic acid-like substances cooperated in the formation and stabilization of SeNPs. Furthermore, CSeNPs (bandgap: 1.68 eV) had more desirable photocatalytic performance than DSeNPs (bandgap: 1.84 eV). Under the light condition, CSeNPs could degrade Rhodamine B faster without adding hydrogen peroxide. This experiment provided a new insight into the resource utilization of activated sludge and a reference for the synthesis of nanometer selenium with excellent performance. Science of the Total Environment published new progress about Domestic wastewater. 492-62-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Computed Properties of 492-62-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Prakash, Anand; Vadivel, Vellingiri published the artcile< Citral and linalool nanoemulsions: impact of synergism and ripening inhibitors on the stability and antibacterial activity against Listeria monocytogenes>, Name: 3,7-Dimethylocta-1,6-dien-3-ol, the main research area is Listeria citral linalool nanoemulsion antibacterial activity ripening inhibitor synergism; Citral; Linalool; Listeria monocytogenes; Nanoemulsions; Ripening inhibitors; Sesame oil.

The present work explored the influence of individual and combinations of citral and linalool along with different Ostwald ripening inhibitors on the nanoemulsion stability and their antibacterial activity against Listeria monocytogenes. Nine different nanoemulsions (N1-N9) containing individual or combinations of citral, linalool with or without ripening inhibitors (medium chain triglycerides, coconut oil, sesame oil and castor oil) were formulated with 5% Tween-80 using ultrasonic emulsification. N1 formulation containing 5% citral without ripening inhibitors showed the least mean droplet diameter of 20.44 nm. Addition of linalool with the citral nanoemulsions was found to have deleterious effect on the thermodn. and kinetic stabilities. Incorporation of ripening inhibitors controlled the increase of droplet size and polydispersity index in N6-N9 during the 90 days storage period, but decreased their antibacterial activity. N8 formulation containing sesame oil as ripening inhibitor was found to be the best in controlling Ostwald ripening. N1 formulation which showed the best antibacterial activity (MIC 0.312%) was found to disrupt the bacterial membrane integrity. N1 formulation also showed a promising biofilm inhibition of 83.51%. Therefore, N1 formulation containing 5% citral could be recommended as an efficient disinfectant against food-borne pathogen Listeria monoctyogenes in food industry. Moreover, addition of sesame oil in the nanoemulsion formulation of citral or linalool could increase their stability.

Journal of Food Science and Technology (New Delhi, India) published new progress about Acoustic emulsification. 78-70-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C10H18O, Name: 3,7-Dimethylocta-1,6-dien-3-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Alonso-Gil, Santiago published the artcile< MonteCarbo : A software to generate and dock multifunctionalized ring molecules>, SDS of cas: 492-62-6, the main research area is software multifunctionalized ring active site glycosidase; Monte Carlo; carbohydrates; conformations; docking; drug design.

MonteCarbo is an open-source software to construct simple 5-, 6-, and 7-membered ring multifunctionalized monosaccharides and nucleobases and dock them into the active site of carbohydrate-active enzymes. The core bash script executes simple orders to generate the Z-matrix of the neutral mol. of interest. After that, a Fortran90 code based on a pseudo-random number generator (Monte Carlo method) is executed to assign dihedral angles to the different rotamers present in the structure (ring and rotating functional groups). The program also has a generalized internal coordinates (GIC) implementation of the Cremer and Pople puckering coordinates ring. Once the structures are generated and optimized, a second code is ready to execute in serial the docking of multiple conformers in the active site of a wide family of enzymes.

Journal of Computational Chemistry published new progress about Computer program. 492-62-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, SDS of cas: 492-62-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Gu, Jinyan; Zhang, Haihui; Wen, Chaoting; Zhang, Jixian; He, Yuanqing; Ma, Haile; Duan, Yuqing published the artcile< Purification, characterization, antioxidant and immunological activity of polysaccharide from Sagittaria sagittifolia L.>, Related Products of 3458-28-4, the main research area is Sagittaria polysaccharide purification antioxidant immunol; Antioxidant; Immunomodulatory; Sagittaria sagittifolia L. polysaccharide.

As a healthy food and traditional Chinese medicine, sagittaria sagittifolia L. has been used for a long history. Nevertheless, reports on the bioactivity and chem. characterization of S. sagittifolia L. polysaccharides are still very rare. In this paper, ultrasound-assisted method (UAE) was used to extract S. sagittifolia L. polysaccharides, after alc. precipitation and column chromatog. isolation, the structural characteristics, antioxidant and immunol. activities of the purified polysaccharide (SPU60-W) were preliminarily investigated. The results indicated SPU60-W (16.62 kDa) was a pyranoid polysaccharide containing α-glycosidic bond composed of mannose, xylose, and glucose with a molar ratio of 2.69:2.04:95.27. It consisted of slender wormlike strands, which may involve some degree of aggregation of helixes, as well as a small proportion of irregular spherical structures. Furthermore, antioxidant activity anal. showed that SPU60-W possess excellent hydroxyl and ABTS radical scavenging activity comparable to vitamin C (Vc), and moderate DPPH radical scavenging activity. Immunity tests suggested that SPU60-W significantly promoted the proliferation, phagocytosis and NO production of mouse macrophage RAW264.7. According to this study, SPU60-W might be utilized as a potent antioxidant and immunomodulator in food and medicinal industry.

Food Research International published new progress about Antioxidants. 3458-28-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Related Products of 3458-28-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Sidana, Jasmeen; Foley, William J.; Singh, Inder Pal published the artcile< Quantitative analysis of euglobals in Eucalyptus loxophleba leaves by qNMR>, Related Products of 4396-13-8, the main research area is euglobal analysis Eucalyptus leaf NMR diformylphloroglucinol monoterpene adduct; NMR analysis euglobal adduct sabinene alpha beta phellandrene adduct.

A simple, rapid, accurate and selective 1H NMR spectroscopic method to detect and quantify euglobals in the leaves of Eucalyptus loxophleba ssp. lissophloia has been developed. The method allows for the estimation of total concentration of diformylphloroglucinol-monoterpene adducts, as well as the quantitation of sabinene- and α/β-phellandrene-adducts, sep. The method was validated for accuracy, precision and linearity using as reference standards 2-Et phenol and mixtures of jensenone, a monomeric formylated phloroglucinol, and 2-ethyl phenol.

Natural Product Communications published new progress about Addition compounds Role: ANT (Analyte), BSU (Biological Study, Unclassified), ANST (Analytical Study), BIOL (Biological Study). 4396-13-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H6O5, Related Products of 4396-13-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Stankovic, Ivana M.; Blagojevic Filipovic, Jelena P.; Zaric, Snezana D. published the artcile< Carbohydrate - Protein aromatic ring interactions beyond CH/π interactions: A Protein Data Bank survey and quantum chemical calculations>, Name: (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol, the main research area is glucose carbohydrate protein aromatic ring interaction quantum chem method; Aromatic amino acids; CH/π interactions; Carbohydrates; Stacking interactions.

The geometries of the contacts between monosaccharides and aromatic rings of amino acids found in X-ray crystallog. structures, in the Protein Data Bank (PDB), were analyzed, while the energies of the interactions were calculated using quantum chem. method. We found 1913 sugar/aromatic ring contacts, 1054 of them (55%) with CH/π interactions and 859 of them (45%) without CH/π interactions. We showed that only the carbohydrate/aromatic contacts with CH/π interactions are preferentially parallel and enable sliding in the plane parallel to aromatic ring. The calculated interaction energies in systems with CH/π interactions are in the range from -1.7 kcal/mol to -6.8 kcal/mol, while in the systems without CH/π interactions are in the range -0.2 to -3.2 kcal/mol. Hence, the binding that does not include CH/π interactions, can also be important for aromatic amino acid and carbohydrate binding processes, since some of these interactions can be as strong as the CH/π interactions. At the same time, these interactions can be weak enough to enable releasing of small carbohydrate fragments after the enzymic reaction. The anal. of the protein-substrate patterns showed that every second or third carbohydrate unit in long substrates stacks with protein aromatic amino acids.

International Journal of Biological Macromolecules published new progress about Carbohydrates Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 492-62-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Name: (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhang, Yaoyao; Wang, Jin; Cao, Xianshuang; Liu, Wei; Yu, Hongwei; Ye, Lidan published the artcile< High-level production of linalool by engineered Saccharomyces cerevisiae harboring dual mevalonate pathways in mitochondria and cytoplasm>, Recommanded Product: 3,7-Dimethylocta-1,6-dien-3-ol, the main research area is ERG20 mutant; Linalool; MVA pathway; Pathway compartmentation; Saccharomyces cerevisiae.

Linalool, a valuable monoterpene alc., is widely used in cosmetics and flavoring ingredients. However, its scalable production by microbial fermentation is not yet achieved. In this work, considerable increase in linalool production was obtained in Saccharomyces cerevisiae by dual metabolic engineering of the mevalonic acid (MVA) pathway in both mitochondria and cytoplasm. A farnesyl pyrophosphate synthase mutant ERG20F96W/N127W and a linalool synthase from Cinnamomum osmophloeum (CoLIS) were introduced and meanwhile the endogenous ERG20 was down-regulated to prevent the competitive loss of precursor. In addition, overexpression of the proteins of CoLIS and ERG20F96W/N127W and another copy of the same enzymes CoLIS/ERG20F96W/N127W with mitochondrial localization signal (MLS) were carried out to further pull the flux to linalool. Finally, a maximum linalool titer of 23.45 mg/L was obtained in a batch fermentation with sucrose as carbon source. This combinatorial engineering strategy may provide hints for biosynthesis of other monoterpenes.

Enzyme and Microbial Technology published new progress about 78-70-6. 78-70-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C10H18O, Recommanded Product: 3,7-Dimethylocta-1,6-dien-3-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Niu, Junfeng; Wang, Shangping; Wang, Bulei; Chen, Lijun; Zhao, Guangming; Liu, Shuai; Wang, Shiqiang; Wang, Zhezhi published the artcile< Structure and anti-tumor activity of a polysaccharide from Bletilla ochracea Schltr.>, Application In Synthesis of 3458-28-4, the main research area is Bletilla polysaccharide structure antitumor activity; Anti-tumor; Bletilla ochracea; Immuno-modulation; Polysaccharide; Structure.

The polysaccharide fraction of Bletilla ochracea (BOP) was isolated from its tubers, and purified by DEAE-52 Cellulose and Sephadex G-200 column chromatog. The structural features of BOP were analyzed by GC-MS, HPLP, FT-IR, methylation and NMR. The average mol. weight of BOP was approx. 4.9 × 105 Da, and the monosaccharide composition was 7.88:2.12 mix of mannose and glucose. Although BOP had no effect on the proliferation rate of CT26 colon carcinoma cells, it significantly inhibited tumor xenograft growth in vivo by stimulating CD4+ T cell expansion in the spleen of the tumor-bearing mice. Taken together, BOP is a potent immunomodulatory agent that can be considered for anti-tumor therapy.

International Journal of Biological Macromolecules published new progress about Antitumor agents. 3458-28-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Application In Synthesis of 3458-28-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts