Tag: M.W=150-200

Lian, Chen; Li, Hai-Lou; Yang, Guo-Yu published the artcile< A μ-AsO4-Bridging Hexadecanuclear Ni-Substituted Polyoxotungstate>, Product Details of C8H10OS, the main research area is crystal structure arsenate bridging hexadecanuclear nickel substituted silicotungstate; nickel substituted silicotungstate preparation electrochem reduction oxidation catalyst.

A novel tetrahedral μ-AsO4-bridging hexadecanuclear nickel-substituted silicotungstate (ST) Na21H10[(AsO4){Ni8(OH)6(H2O)2(CO3)2(A-α-SiW9O34)2}2]·60H2O (1) was made by the reactions of trivacant [A-α-SiW9O34]10- ({SiW9}) units with Ni2+ cations and Na3AsO4·12H2O and characterized by IR spectrometry, elemental anal., TGA, and powder x-ray diffraction (PXRD). 1 Contains [(AsO4){Ni8(OH)6(H2O)2(CO3)2(A-α-SiW9O34)2}2]31-, a novel polyoxoanion built by four trivacant Keggin [A-α-SiW9O34]10- fragments linked through an unprecedented [(AsO4){Ni8(OH)6(H2O)2(CO3)2}2]9+ cluster, where the tetrahedral AsO4 acts as an exclusively μ2-bridging unit to link multiple Ni centers; such a connection mode appears for the 1st time in polyoxometalate chem. Also, the electrochem. and catalytic oxidation properties of 1 were studied.

Inorganic Chemistry published new progress about Aromatic compounds, sulfones Role: SPN (Synthetic Preparation), PREP (Preparation). 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Product Details of C8H10OS.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Agatonovic-Kustrin, S.; Kustrin, E.; Gegechkori, V.; Morton, D. W. published the artcile< Anxiolytic Terpenoids and Aromatherapy for Anxiety and Depression>, Synthetic Route of 78-70-6, the main research area is review anxiolytic terpenoid aromatherapy anxiety depression; Anxiety; Aromatherapy; Depression; Essential oil; Terpenoids.

A review. In our society, anxiety and depression are serious health issues that affect a large proportion of the population. Unfortunately, drug therapies are not always effective and can lead to drug abuse, delay of therapeutic effect, dependence, and tolerance. Traditionally, aromatherapy has also been used for anxiety relief and mood improvement. The use of essential oils, in relieving anxiety and depression, does not have the disadvantages associated with currently used drug therapies. In-vivo studies on animal models have verified the anxiolytic effects of these essential oils and the interactions of their major components with central nervous system receptors. Therefore, it seems reasonable to argue that the modulation of glutamate and GABA neurotransmitter systems are likely to be the critical mechanisms responsible for the sedative, anxiolytic, and anticonvulsant proprieties of linalool and essential oils containing linalool in significant proportions. Popular anxiolytic essential oils are generally rich in terpenoid alcs. like linalool, geraniol and citronellol, and the monoterpene limonene (or citral). Therefore, other essential oils or formulations that contain these terpenoids as major components may serve as important aromatherapeutics for relief of anxiety.

Advances in Experimental Medicine and Biology published new progress about Anticonvulsants. 78-70-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C10H18O, Synthetic Route of 78-70-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wu, Jie; Mu, Ran; Sun, Mingna; Zhao, Nan; Pan, Miaomiao; Li, Hongshuang; Dong, Yi; Sun, Zhaogang; Bai, Jie; Hu, Minwan; Nathan, Carl F.; Javid, Babak; Liu, Gang published the artcile< Derivatives of Natural Product Agrimophol as Disruptors of Intrabacterial pH Homeostasis in Mycobacterium tuberculosis>, Related Products of 4396-13-8, the main research area is agrimophol derivative antitubercular disruption pH homeostasis Mycobacterium tuberculosis; agrimophol; coumarin; diphenylmethane scaffold; intrabacterial pH homeostasis; pharmacophores.

This article reports the rational medicinal chem. of a natural product, agrimophol (1), as a new disruptor of intrabacterial pH (pHIB) homeostasis in Mycobacterium tuberculosis (Mtb). Through the systematic investigation of the structure-activity relationship of 1, scaffold-hopping of the diphenylmethane scaffold, pharmacophore displacement strategies, and studies of the structure-metabolism relationship, a new derivative 5a was achieved. Compound 5a showed 100-fold increased potency in the ability to reduce pHIB to pH 6.0 and similarly improved mycobactericidal activity compared with 1 against both Mycobacterium bovis-BCG and Mtb. Compound 5a possessed improved metabolic stability in human liver microsomes and hepatocytes, lower cytotoxicity, higher selectivity index, and similar pKa value to natural 1. This study introduces a novel scaffold to an old drug, resulting in improved mycobactericidal activity through decreasing pHIB, and may contribute to the critical search for new agents to overcome drug resistance and persistence in the treatment of tuberculosis.

ACS Infectious Diseases published new progress about Blood proteins Role: BSU (Biological Study, Unclassified), BIOL (Biological Study) (human). 4396-13-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H6O5, Related Products of 4396-13-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Nazarzadeh, Somayeh; Ghorbani-Choghamarani, Arash; Tahanpesar, Elham published the artcile< Synthesis and characterization of MCM-41@XA@Ni(II) as versatile and heterogeneous catalyst for efficient oxidation of sulfides and acetylation of alcohols under solvent-free conditions>, Quality Control of 699-12-7, the main research area is mesoporous silica catalyst alc acetylation sulfide oxidation thermal property.

Herein, Ni(II) immobilized on modified mesoporous silica MCM-41 was designed and synthesized via a facile sequential strategy. The structure of the catalyst was characterized by X-ray diffraction. The thermal property of the as-synthesized materials was studied using thermogravimetric-DTA. The average particles size and morphol. of MCM-41@XA@Ni(II) were investigated using SEM and transmission electron microscopy. This nanostructure catalyst was effective for the selective oxidation of sulfides and acetylation of alcs. in solvent-free conditions. The easy recyclability of the catalyst and their complete chemoselectivity toward the sulfur group of substrates in the oxidation of sulfides are important “”green”” attributes of this catalyst.

Journal of the Iranian Chemical Society published new progress about Acetylation. 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Quality Control of 699-12-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wu, Boping; Cao, Xiangmei; Liu, Hongru; Zhu, Changqing; Klee, Harry; Zhang, Bo; Chen, Kunsong published the artcile< UDP-glucosyltransferase PpUGT85A2 controls volatile glycosylation in peach>, SDS of cas: 78-70-6, the main research area is Prunus UGT85A2 gene fruit ripening linalyl beta D glucoside.

The monoterpene linalool is a major contributor to aroma and flavor in peach (Prunus persica) fruit. It accumulates during fruit ripening, where up to ∼40% of the compound is present in a non-volatile glycosylated form, which affects flavor quality and consumer perception by retronasal perception during tasting. Despite the importance of this sequestration to flavor, the UDP-glycosyltransferase (UGT) responsible for linalool glycosylation has not been identified in peach. UGT gene expression during peach fruit ripening and among different peach cultivars was analyzed using RNA sequencing, and transcripts correlated with linalyl-β-d-glucoside were selected as candidates for functional anal. Kinetic resolution of a racemic mixture of R,S-linalool was shown for PpUGT85A2, with a slight preference for S-(+)-linalool. PpUGT85A2 was shown to catalyze synthesis of linalyl-β-d-glucoside in vitro, although it did not exhibit the highest enzyme activity between tested substrates. Subcellular localization of PpUGT85A2 in the cytoplasm and nucleus was detected. Application of linalool to peach leaf disks promoted PpUGT85A2 expression and linalyl-β-d-glucoside generation. Transient expression in peach fruit and stable overexpression in tobacco and Arabidopsis resulted in significant accumulation of linalyl-β-d-glucoside in vivo. Taken together, the results indicate that PpUGT85A2 expression is a major control point predicting linalyl-β-d-glucoside content.

Journal of Experimental Botany published new progress about Arabidopsis thaliana. 78-70-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C10H18O, SDS of cas: 78-70-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Campos, Estefania V. R.; Proenca, Patricia L. F.; Oliveira, Jhones L.; Bakshi, Mansi; Abhilash, P. C.; Fraceto, Leonardo F. published the artcile< Use of botanical insecticides for sustainable agriculture: Future perspectives>, HPLC of Formula: 78-70-6, the main research area is review botanical insecticide sustainable agricultural practice.

A review. Recent decades have witnessed major growth in the use of agrochems. worldwide, – for maximizing the food production for a rapidly growing human population. However, the indiscriminate use of these substances especially the pesticides has led to the accumulation of toxic residues in food, soil, air, and water, as well as the development of resistance in pests. Moreover, pesticides affect soil enzymes, which are essential catalysts that govern soil quality. In order to meet the food security, it is necessary to produce more food, sustainably and safely, in a diminishing area of available arable land and with decreased water resources. Given this situation, there is an increased interest in the use of alternative substances to synthetic agrochems. that present less risk to the environment and human health while increasing the food safety. Promising results have been obtained using compounds derived from aromatic plants for the control of agricultural pests. Such compounds of botanical origin can be highly effective, with multiple mechanisms of action, while at the same time having low toxicity towards nontarget organisms. However, the large-scale application of these substances for pest control is limited by their poor stability and other technol. issues. In this backdrop, the present work discusses perspectives for the use of compounds of botanical origin, as well as strategies employing the encapsulation techniques that can contribute to the development of systems for use in sustainable agricultural practices.

Ecological Indicators published new progress about Food safety. 78-70-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C10H18O, HPLC of Formula: 78-70-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhu, Rugang; Zhang, Xinyu; Wang, Yu; Zhang, Lijiao; Zhao, Jing; Chen, Gang; Fan, Jungang; Jia, Youfeng; Yan, Fengwen; Ning, Chong published the artcile< Characterization of polysaccharide fractions from fruit of Actinidia arguta and assessment of their antioxidant and antiglycated activities>, COA of Formula: C6H12O6, the main research area is polysaccharide Actinidia antioxidant AGE; Actinidia argute; Antiglycation; Antioxidation; Characterization; Polysaccharide.

A novel cell-wall polysaccharides (AAPs) were extracted from the fruits of Actinidia arguta and separated into four parts which were named water-eluted polysaccharide (WPS), salt-eluted polysaccharide (SPS)-1, SPS-2 and SPS-3. The monosaccharide composition and structural anal. showed that SPS-3 and SPS-2 were homogalacturonan (HG)-rich pectin, SPS-1 was rhamnogalacturonan (RG)-rich pectin and WPS was starch-like polysaccharides. All four kinds of polysaccharides displayed the ability to scavenge free radicals, chelate iron ion, inhibit lipid peroxidation and inhibit protein glycation, but SPS was obviously stronger than WPS. Especially SPS-3 displayed the strongest antioxidant and anti-glycated activities. In addition, the inhibitory effect of AAPs on AGEs formation is attributed to the inhibitory activity on the production of protein carbonyl group and the protective effects on the protein thiol group but not the scavenging capacity of dicarbonyl compounds, suggesting that its mechanisms of antiglycated effects may be of concern to their antioxidant activities.

Carbohydrate Polymers published new progress about Actinidia arguta. 3458-28-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, COA of Formula: C6H12O6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Xu, Yaqin; Liu, Ningyue; Fu, Xueting; Wang, Lixuan; Yang, Yu; Ren, Yaoyu; Liu, Jiayin; Wang, Libo published the artcile< Structural characteristics, biological, rheological and thermal properties of the polysaccharide and the degraded polysaccharide from raspberry fruits>, Related Products of 3458-28-4, the main research area is Rubus fruit polysaccharide degradation structural antioxidant rheol thermal property; Activities; Fe(2+)-H(2)O(2) degradation; Polysaccharides; Rheological behavior; Structural characterization; Thermal properties.

A native polysaccharide (RCPI) with sugar content of 79.94 ± 0.57% was isolated from raspberry fruits. A degraded polysaccharide (DRCPI) with sugar content of 83.82 ± 0.71% was obtained from the crude polysaccharides after degradation by Fe2+-H2O2 treatment. The mol. weights of RCPI and DRCPI were determined to be 411,000 and 8010 Da, resp. GC anal. revealed that both RCPI and DRCPI were composed of the same monosaccharides (rhamnose, arabinose, xylose, mannose, glucose, galactose, and galacturonic acid) in different molar ratios. IR and NMR spectroscopy confirmed that RCPI and DRCPI possessed similar structural characteristics, although DRCPI displayed higher antioxidant activities and greater thermal stability. Furthermore, DRCPI exhibited excellent rheol. properties. These data provide evidence to support the application of raspberry-derived polysaccharides in functional foods.

International Journal of Biological Macromolecules published new progress about Carbohydrates Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 3458-28-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Related Products of 3458-28-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Tamoradi, Taiebeh; Ghorbani-Choghamarani, Arash; Ghadermazi, Mohammad published the artcile< CoFe2O4@glycine-M (M = Pr, Tb and Yb): Three green, novel, efficient and magnetically-recoverable nanocatalysts for synthesis of 5-substituted 1H-tetrazoles and oxidation of sulfides in green condition>, Synthetic Route of 699-12-7, the main research area is tetrazole oxidation sulfide Cobalt ferrite glycine nanocatalyst green condition.

Three novel and green nano-scale magnetic solid base catalysts (CoFe2O4@glycine-M (M = Pr, Tb and Yb)) have been synthesized and characterized by XRD, TGA, VSM, EDX, ICP-OES, SEM and FT-IR spectroscopy. These robust nanohybrid catalysts as efficient and reusable heterogeneous nanocatalyst systems were used for synthesis of 5-substituted 1H-tetrazoles and sulfoxides in green condition. The present methodol. has outstanding advantages such as simplicity of procedure, facile synthesis, high activity, easy isolation of the products and reusability for several consecutive runs without significant loss of their catalytic efficiency.

Solid State Sciences published new progress about Nanocatalysts. 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Synthetic Route of 699-12-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Dong, Yue; Sui, Mingrui; Jiang, Yiying; Wu, Jianyu; Wang, Xin published the artcile< Dibutyl phthalate weakens the role of electroactive biofilm as an efficient wastewater handler and related mechanism>, Reference of 492-62-6, the main research area is dibutyl phthalate electroactive biofilm wastewater handler related mechanism; Bacterial activity; Dibutyl phthalate exposure; Electroactive biofilm; Electron exchange capacity; Pollutant degradation.

Plasticizer plays an imperceptible role in interfering with the structure and function of wastewater biofilms, but the inherent influence mechanism still remains unknown. Here, the responses in electrochem., structural, microbial properties of electroactive biofilm (EAB) to plasticizer (di-Bu phthalate, DBP) were comprehensively elucidated, especially for the property variation of extracellular polymeric substances (EPS). The biofilm-0 in DBP-absent environment contributed to 22.9% and 63.9% higher current, compared to those in 1 mg/L and 10 mg/L DBP environment (biofilm-1 and biofilm-10). Chronic exposure to high-concentration DBP significantly boosted the content and distribution width of polysaccharide in EPS, but the electron exchange capacity of EPS decreased 76.6% to 0.146μmol e-/mg EPS for biofilm-10. The bacteria were subjected to metabolic function loss, in terms of esterase activity and membrane integrity, by using flow cytometry. The DBP exposure also imposed selective pressure on enrich EPS-secretion-related bacteria, while the Geobacter species decreased from 71.2% (biofilm-0) to 55.8% (biofilm-10). Consequently, the DBP exposure suppressed the pollutant degradation rate, which provided new insights into the EAB role as a promising core for wastewater treatment in plasticizer-existing environments.

Science of the Total Environment published new progress about Acinetobacter. 492-62-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Reference of 492-62-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts