Tag: M.W=150-200

Alsabte, Ahmed published the artcileEffects of Volatile Organic Compounds (VOCs) emitted by citrus infested with Aonidiella aurantii on the predator Rhyzobius lophanthae attraction, Safety of cis-3,7-Dimethyl-2,6-Octadien-1-Ol, the publication is Phytoparasitica (2022), 50(3), 645-653, database is CAplus.

This study identifies the volatile organic compounds (VOCs) emitted by citrus when infested with California red scale (Aonidiella aurantii) and determines which of these elicit behavior responses in the predator Rhyzobius lophanthae. Headspace solid-phase micro extractions (HS-SPME) technique combined with gas chromatog.-mass spectrometry (GC-MS) was used to identify compounds and Y-tube olfactometer to determine R. lophanthae behavior responses. According to the results, 22 VOCs were detected in infested citrus plants and some of them were increased in lemon, orange and tangerine by A. aurantii infestation. R. lophanthae individuals were attracted to infested citrus saplings. According to bioassays with the olfactometer, they were attracted to Me salicylate and D-limonene at dosages of 1 and 10μL/mL by using a Y-tube olfactometer. These results explain how citrus volatiles can affect the response of the predator R. lophanthae.

Phytoparasitica published new progress about 106-25-2. 106-25-2 belongs to alcohols-buliding-blocks, auxiliary class Natural product, name is cis-3,7-Dimethyl-2,6-Octadien-1-Ol, and the molecular formula is C10H18O, Safety of cis-3,7-Dimethyl-2,6-Octadien-1-Ol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Zhao, Fengqian published the artcileRadical Carbonylation under Low CO Pressure: Synthesis of Esters from Activated Alkylamines at Transition Metal-Free Conditions, Product Details of C10H9NO, the publication is Chinese Journal of Chemistry (2021), 39(4), 927-932, database is CAplus.

High CO pressure (> 40 bar) is usually needed in radical carbonylation reactions in the absence of metal catalyst. In this communication, a transition-metal-free radical carbonylation of activated alkylamines with phenols and alcs. under low CO pressure (1-6 bar) was developed. Various esters were obtained in moderate to excellent yields under simple reaction conditions with good functional group compatibility.

Chinese Journal of Chemistry published new progress about 23351-09-9. 23351-09-9 belongs to alcohols-buliding-blocks, auxiliary class Pyrrole,Benzene,Alcohol, name is 4-(1H-Pyrrol-1-yl)phenol, and the molecular formula is C39H35N5O8, Product Details of C10H9NO.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Soganci, Tugba published the artcileFerrocenyldithiophosphonate Containing Conducting Polymers and Theirs Electrochromic Application, Formula: C10H9NO, the publication is Journal of Inorganic and Organometallic Polymers and Materials (2015), 25(5), 1011-1018, database is CAplus.

In this study, a new ferrocenyldithiophosphonate functionalized; [O-1-(4-phenyl)-1H-pyrrole ferrocenyldithiophosphonate (TPFc)] monomer and its conductive copolymers with pyrrole and 4-(2,5-di(thiophen-2-yl)-1H-pyrrol-1-yl)butane-1-amine were synthesized, characterized and their electrochromic properties were investigated. The spectroelectrochem. analyses demonstrated that the copolymer films reveal a reversible cycling with distinctive color changes in their reduced/oxidized forms. For the copolymer films P(TPFc-co-Py)/DCM, P(TPFc-co-Py)/CH3CN and P(TPFc-co-TPA)/DCM, the maximum optical contrasts (ΔT %) were measured as 28, 12 and 27% at 800, 900 and 900 nm, resp. Spectroelectrochem. anal. also revealed that all copolymers prepared with TPFc have lower band gaps compared to those of corresponding polymers.

Journal of Inorganic and Organometallic Polymers and Materials published new progress about 23351-09-9. 23351-09-9 belongs to alcohols-buliding-blocks, auxiliary class Pyrrole,Benzene,Alcohol, name is 4-(1H-Pyrrol-1-yl)phenol, and the molecular formula is C4H6O3, Formula: C10H9NO.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Ak, Metin published the artcileElectrochemical properties of a new star-shaped pyrrole monomer and its electrochromic applications, Product Details of C10H9NO, the publication is Macromolecular Chemistry and Physics (2006), 207(15), 1351-1358, database is CAplus.

A new monomer, 2,4,6-tris(4-(1H-pyrrol-1-yl)phenoxy)-1,3,5-triazine (Tria-Py) was synthesized via the reaction of 4-(1H-pyrrol-1-yl)phenol with 2,4,6-trichloro-1,3,5-triazine. It was electrochem. polymerized in a dichloromethane/acetonitrile solvent mixture The polymer P(Tria-Py) was characterized via CV,FTIR,SEM and UV-vis spectroscopy. Spectroelectrochem. anal. revealed electronic transitions at 346, 508 and 665 nm, revealing π to π* transitions, and polaron and bipolaron band formations resp. We also made a dual-type, complementary-colored electrochromic device using P(Tria-Py)/poly(3,4-ethylenedioxythiophene) (PEDOT) in a sandwich configuration. The device switches between dark blue and red colors with a switching time of 2.2 s and an optical contrast (% ΔT) of 25%.

Macromolecular Chemistry and Physics published new progress about 23351-09-9. 23351-09-9 belongs to alcohols-buliding-blocks, auxiliary class Pyrrole,Benzene,Alcohol, name is 4-(1H-Pyrrol-1-yl)phenol, and the molecular formula is C10H9NO, Product Details of C10H9NO.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Soares, Ruben R. G. published the artcileSample-to-answer COVID-19 nucleic acid testing using a low-cost centrifugal microfluidic platform with bead-based signal enhancement and smartphone read-out, Product Details of C10H15NO, the publication is Lab on a Chip (2021), 21(15), 2932-2944, database is CAplus and MEDLINE.

With its origin estimated around Dec. 2019 in Wuhan, China, the ongoing SARS-CoV-2 pandemic is a major global health challenge. The demand for scalable, rapid and sensitive viral diagnostics is thus particularly pressing at present to help contain the rapid spread of infection and prevent overwhelming the capacity of health systems. While high-income countries have managed to rapidly expand diagnostic capacities, such is not the case in resource-limited settings of low- to medium-income countries. Aiming at developing cost-effective viral load detection systems for point-of-care COVID-19 diagnostics in resource-limited and resource-rich settings alike, we report the development of an integrated modular centrifugal microfluidic platform to perform loop-mediated isothermal amplification (LAMP) of viral RNA directly from heat-inactivated nasopharyngeal swab samples. The disks were pre-packed with dried n-benzyl-n-methylethanolamine modified agarose beads used to selectively remove primer dimers, inactivate the reaction post-amplification and allowing enhanced fluorescence detection via a smartphone camera. Sample-to-answer anal. within 1 h from sample collection and a detection limit of approx. 100 RNA copies in 10μL reaction volume were achieved. The platform was validated with a panel of 162 nasopharyngeal swab samples collected from patients with COVID-19 symptoms, providing a sensitivity of 96.6% (82.2-99.9%, 95% CI) for samples with Ct values below 26 and a specificity of 100% (90-100%, 95% CI), thus being fit-for-purpose to diagnose patients with a high risk of viral transmission. These results show significant promise towards bringing routine point-of-care COVID-19 diagnostics to resource-limited settings.

Lab on a Chip published new progress about 101-98-4. 101-98-4 belongs to alcohols-buliding-blocks, auxiliary class Amine,Benzene,Alcohol, name is 2-(Benzyl(methyl)amino)ethanol, and the molecular formula is C9H5FO2, Product Details of C10H15NO.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Li, Yu-Hsun published the artcileDirect Transformation of Nitroalkanes to Nitriles Enabled by Visible-Light Photoredox Catalysis and a Domino Reaction Process, Name: 2-Methoxy-4-(2-nitroethyl)phenol, the publication is Organic Letters (2019), 21(19), 7750-7754, database is CAplus and MEDLINE.

A mild and convenient process for direct transformation of nitroalkanes to the corresponding nitriles was developed using a visible-light photoredox catalysis strategy with household decorative blue LEDs and the additives of Et₃N and DIPIBA (or DIPEA). Application of the process in secondary nitroalkanes bearing a β-alc. resulted in a domino process of the retro-Henry reaction and the subsequent acetalization, aldol, cyanohydrin, and ring-contraction reactions with stereoselectivities. The photocatalytic reaction was demonstrated by a continuous flow method.

Organic Letters published new progress about 528594-30-1. 528594-30-1 belongs to alcohols-buliding-blocks, auxiliary class Nitro Compound,Benzene,Phenol,Ether, name is 2-Methoxy-4-(2-nitroethyl)phenol, and the molecular formula is C9H11NO4, Name: 2-Methoxy-4-(2-nitroethyl)phenol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Vagapova, L. I. published the artcileKabachnik-Fields Reaction in the Synthesis of New Acetal-Containing Aminophosphine Oxides, Quality Control of 6346-09-4, the publication is Russian Journal of General Chemistry (2018), 88(9), 1912-1914, database is CAplus.

The Kabachnik-Fields reaction in a ternary system of 4,4-diethoxybutylamine-dialkyl(tolyl)-phosphine acid-3,5-di-tert-butyl-4-hydroxybenzaldehyde (or paraformaldehyde) afforded new aminophosphine oxides containing 3,5-di-tert-butyl-4-hydroxyphenol moiety and an acetal group.

Russian Journal of General Chemistry published new progress about 6346-09-4. 6346-09-4 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Ether, name is 4,4-Diethoxybutan-1-amine, and the molecular formula is C11H8O3, Quality Control of 6346-09-4.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Kirkland, Thomas A. published the artcileSynthesis of glutamic acid analogs as potent inhibitors of leukotriene A₄ hydrolase, Application of 4-(1H-Pyrrol-1-yl)phenol, the publication is Bioorganic & Medicinal Chemistry (2008), 16(9), 4963-4983, database is CAplus and MEDLINE.

Leukotriene B₄ (LTB₄) is a potent pro-inflammatory mediator that has been implicated in the pathogenesis of multiple diseases, including psoriasis, inflammatory bowel disease, multiple sclerosis and asthma. As a method to decrease the level of LTB₄ and possibly identify novel treatments, inhibitors of the LTB₄ biosynthetic enzyme, leukotriene A₄ hydrolase (LTA₄-h), have been explored. Here, the authors describe the discovery of a potent inhibitor of LTA₄-h, arylamide of glutamic acid derivative I, starting from Boc-Glu[NHC₆H₄(OCH₂Ph)-4]-OH. Analogs of I are then described, focusing on compounds that are both active and stable in whole blood. This effort culminated in the identification of amino alc. II and amino ester III which meet these criteria.

Bioorganic & Medicinal Chemistry published new progress about 23351-09-9. 23351-09-9 belongs to alcohols-buliding-blocks, auxiliary class Pyrrole,Benzene,Alcohol, name is 4-(1H-Pyrrol-1-yl)phenol, and the molecular formula is C10H9NO, Application of 4-(1H-Pyrrol-1-yl)phenol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Helal, Mustafa R. published the artcileConformational analysis of some β-halohydrins via G3 calculations, Synthetic Route of 55376-31-3, the publication is Jordan Journal of Chemistry (2013), 8(1), 19-30, database is CAplus.

The conformational anal. of fifteen β-halohydrins, XCR₁R₂CR₃R₄OH, (X = F, Cl and Br) had been studied by ab initio G3 method. The enthalpies of formation values were calculated for nine conformers of each β-halohydrin. The (g^–, g⁺) and (g⁺, g^–) conformers are the most stable due to intramol. H-bond formation. These H-bonds are weaker than intermol. H-bonds formed between alkyl halides and alcs. This trend is more obvious in fluoro-species. The rotation of C- X bond of (g^–, g⁺) conformers by 360° gives three transition states, this rotation was found to require 6-7 kcal/mol.

Jordan Journal of Chemistry published new progress about 55376-31-3. 55376-31-3 belongs to alcohols-buliding-blocks, auxiliary class Polymerization Reagents,ATRP Initiators, name is 2-Bromo-2-methylpropan-1-ol, and the molecular formula is C4H9BrO, Synthetic Route of 55376-31-3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Azam, Syed Sikander published the artcileInvestigation of novel chemical inhibitors of human lysosomal acid lipase: virtual screening and molecular docking studies, Safety of 4-Morpholino-1,2,5-thiadiazol-3-ol, the publication is Combinatorial Chemistry & High Throughput Screening (2014), 17(5), 473-482, database is CAplus and MEDLINE.

In the current study, identification of new potent small inhibitors of human lysosomal acid lipase using structure-based methods has been reported. Virtual Screening (VS), compounds from literature and mol. docking studies were employed to find the suitable inhibitors against lysosomal acid lipase (LAL). Specifically for this study a homol. model of LipA enzyme was generated based on the structure of dog gastric lipase. As a result of structure-based virtual screening 28 inhibitors were identified from ZINC database. Rest of the inhibitors were selected from literature. Among the studied 65 inhibitors, compound having zinc ID ZINC15707335 exhibiting min. binding affinity and hydrogen bond and hydrophobic interactions with specific amino acid residues was selected as lead compound

Combinatorial Chemistry & High Throughput Screening published new progress about 30165-97-0. 30165-97-0 belongs to alcohols-buliding-blocks, auxiliary class Morpholine,Thiadiazole,Alcohol, name is 4-Morpholino-1,2,5-thiadiazol-3-ol, and the molecular formula is C6H9N3O2S, Safety of 4-Morpholino-1,2,5-thiadiazol-3-ol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts