Tag: M.W=150-200

Kondratenko, Yulia A. published the artcileDiethanolammonium protic ionic liquids – promising buffers for the synthesis of ⁶⁸Ga- labelled radiopharmaceuticals, Quality Control of 86-48-6, the publication is Journal of Molecular Liquids (2022), 117029, database is CAplus.

Fifteen new protic ionic liquids based on diethanolammonium (DEA) salts of carboxylic acids have been synthesized and identified using a complex of physicochem. methods (NMR, FT-IR spectroscopy, elemental, thermal anal.). The crystal structure of diethanolammonium salts of benzoic and 1-hydroxy-2-naphthoic acids was determined for the first time by XRD. A comparative anal. of the conformations of DEA cations was carried out. The effectiveness of synthesized DEA ionic liquids as buffer agents was demonstrated on ⁶⁸Ga-radiolabeling reactions with different chelators and clin. approved peptides.

Journal of Molecular Liquids published new progress about 86-48-6. 86-48-6 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment,Natural product, name is 1-Hydroxy-2-naphthoic acid, and the molecular formula is C11H8O3, Quality Control of 86-48-6.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Devi, Apramita published the artcileTiming of inoculation of Oenococcus oeni and Lactobacillus plantarum in mixed malo-lactic culture along with compatible native yeast influences the polyphenolic, volatile and sensory profile of the Shiraz wines, Application of cis-3,7-Dimethyl-2,6-Octadien-1-Ol, the publication is LWT–Food Science and Technology (2022), 113130, database is CAplus.

Malolactic fermentation (MLF) is a secondary wine fermentation resulting from lactic acid bacteria (Oenococcus oeni or Lactobacillus plantarum), especially in cool climates. MLF reduces acidity, improves body, mouthfeel, aroma complexity, and stabilizes the wine. Nevertheless, the traditional MLF using single culture is often associated with stuck fermentation, increased volatile acidity and color loss in wine. Thus, studies on mixed blend of L. plantarum and O. oeni to improve chem. and sensory profiles are gaining importance. The first study on different timing of inoculation of dual malo-lactic culture for the vinification of Shiraz wine aims to understand interactions between the wine cultures (Saccharomyces cerevisiae AAV2, L. plantarum Lp 1 and O. oeni Oo 1). The wines were compared based on chem. properties, phenolic and volatile profiles, and sensory anal. The study highlighted that early or mid-inoculated MLF wines have higher anthocyanins, flavonoids, syringol, esters, vanillate derivatives, benzaldehyde, and free terpenes compared to traditional MLF wines. The wines were rated high for purple red color, tannin, body, and overall acceptability. Hence, it was concluded that the inoculation of Lp 1 and Oo 1, either after 7 or 14 days of alc. fermentation by yeast AAV2, yield the desired quality Shiraz wine.

LWT–Food Science and Technology published new progress about 106-25-2. 106-25-2 belongs to alcohols-buliding-blocks, auxiliary class Natural product, name is cis-3,7-Dimethyl-2,6-Octadien-1-Ol, and the molecular formula is C10H18O, Application of cis-3,7-Dimethyl-2,6-Octadien-1-Ol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Priyadarshini, S. published the artcileCopper MOF: scope and limitation in catalytic hydroxylation and nitration of aryl halides, COA of Formula: C10H9NO, the publication is Tetrahedron (2013), 69(31), 6409-6414, database is CAplus.

The potential catalytic application of MOFs like [Cu₃(btc)₂] (btc=1,3,5-benzenetricarboxylate), [Cu(bdc)] (bdc=1,4-benzenedicarboxylate), [Cu(pymo)₂] (pymo=2-hydroxypyrimidinalote) and [Cu(i.m.)₂] (i.m.=imidazolate) was explored in the hydroxylation and nitration of aryl halides. Cu₃(btc)₂ was found to be superior for both the reactions furnishing good to excellent yields of the resp. products. The studies demonstrated that MOFs are not recyclable, attributable to their instability in the highly polar and basic conditions demanded for these reactions. Complete transformation of MOFs to copper oxide nanoparticles occurred in hydroxylation, whereas significant alteration in frameworks was observed for the recovered catalyst in nitration.

Tetrahedron published new progress about 23351-09-9. 23351-09-9 belongs to alcohols-buliding-blocks, auxiliary class Pyrrole,Benzene,Alcohol, name is 4-(1H-Pyrrol-1-yl)phenol, and the molecular formula is C10H9NO, COA of Formula: C10H9NO.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Tripathi, Shashank published the artcileConstruction of Highly Functionalized Piperazinones via Post-Ugi Cyclization and Diastereoselective Nucleophilic Addition, Formula: C8H19NO2, the publication is Journal of Organic Chemistry (2020), 85(11), 6910-6923, database is CAplus and MEDLINE.

Aminals were prepared by Ugi multicomponent cyclocondensation reactions of 2-aminoacetaldehyde di-Me acetal, aldehydes or ketones such as 3-indolecarboxaldehyde, carboxylic acids such as benzoic acid, and isocyanides such as benzyl isocyanide. In the presence of BF₃·Et₂O in CH₂Cl₂, the aminals underwent (diastereoselective) substitution reactions with nucleophiles such as Me₃SiR [R = H₂C:CHCH₂, NC, N₃, OCPh(:CH₂)], triethylsilane, or N-methylindole to yield piperazinones such as I (X = Y = O). Ugi reactions with aminoaldehyde acetals with longer carbon chains yielded only acyclic products. I (X = Y = H₂) was prepared as a dragmacidin C analog, while two piperazinones were used to prepare praziquantel analogs.

Journal of Organic Chemistry published new progress about 6346-09-4. 6346-09-4 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Ether, name is 4,4-Diethoxybutan-1-amine, and the molecular formula is C8H10S, Formula: C8H19NO2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Setoodeh, Narjes published the artcileCorrelation of solubility of solid hydrocarbons in supercritical carbon dioxide using different equations of state and mixing rules, Application of 2-Hydroxy-2-phenylacetic acid, the publication is Journal of the Serbian Chemical Society (2022), 87(6), 735-747, database is CAplus.

The supercritical extraction process is a technique that has increasingly been applied in various industries in recent years. Solubility determination in the supercritical region is the key feature for this process. However, high expenses and time consuming experiments for this task obligates the need for process modeling. In this study, a thermodn. model is proposed to correlate the solubility of solid hydrocarbons, namely, 1-hexadecanol, 1-octadecanol, anthracene, benzoin, fluorene, hexamethylbenzene, mandelic acid, naphthalene, palmitic acid, phenanthrene, Pr 4-hydroxybenzoate, pyrene and stearic acid in supercritical conditions, using Peng-Robinson (PR) and Soave-Redlich-Kwong (SRK) equations of state with one-parameter van der Waals (vdW1) and two-parameters (vdW2) and covolume dependent (CVD) mixing rules. For the above combination of equations of state and mixing rules, binary interaction parameters were determined, utilizing the differential evolution optimization strategy. The validity of the model was assessed by comparing the exptl. solubility data with the results obtained from thermodn. model based on average absolute relative deviation (AARD). An empirical correlation was proposed for the correlation of the solid solubilities in supercritical CO₂. For each compound, the constants of this equation were obtained in such a manner to correlate the solubility at different temperatures and pressures.

Journal of the Serbian Chemical Society published new progress about 90-64-2. 90-64-2 belongs to alcohols-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Alcohol,Natural product, name is 2-Hydroxy-2-phenylacetic acid, and the molecular formula is C13H9ClN2O4, Application of 2-Hydroxy-2-phenylacetic acid.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Vagapova, L. I. published the artcileβ- and γ-amino acetals containing phosphine oxide groups. Synthesis and reactions with resorcinol derivatives, Safety of 4,4-Diethoxybutan-1-amine, the publication is Russian Journal of Organic Chemistry (2014), 50(6), 778-782, database is CAplus.

New β- and γ-amino acetals containing phosphine oxide groups were synthesized by the Kabachnik-Fields reaction of β- and γ-amino acetals with paraformaldehyde and dialkylphosphine oxides. Heating of the resulting β- and γ-amino acetals with 2-methylresorcinol and pyrogallol in boiling trifluoroacetic acid afforded (dialkylphosphoryl)(ω,ω-diarylalkyl)ammonium trifluoracetates.

Russian Journal of Organic Chemistry published new progress about 6346-09-4. 6346-09-4 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Ether, name is 4,4-Diethoxybutan-1-amine, and the molecular formula is C8H6ClN, Safety of 4,4-Diethoxybutan-1-amine.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Vagapova, L. I. published the artcileSynthesis and structure of new phosphorylated β- and γ-amino acetals containing a sterically hindered phenol group, Category: alcohols-buliding-blocks, the publication is Russian Journal of Organic Chemistry (2015), 51(9), 1268-1271, database is CAplus.

α-Phosphorylated 3,5-di-tert-butyl-4-methylidenecyclohexa-2,5-dien-1-ones reacted with 3,3-diethoxypropan-1-amine and 4,4-diethoxybutan-1-amine to afford new α-amino phosphonates containing sterically hindered phenol and acetal groups.

Russian Journal of Organic Chemistry published new progress about 6346-09-4. 6346-09-4 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Ether, name is 4,4-Diethoxybutan-1-amine, and the molecular formula is C50H65O4P, Category: alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Zou, Zhuanglei published the artcileSurface modification of waste silicone rubber via alcoholysis reaction and its application in polypropylene toughening, Safety of cis-3,7-Dimethyl-2,6-Octadien-1-Ol, the publication is Journal of Polymer Research (2022), 29(4), 148, database is CAplus.

With the development of power industry, the recycling of waste insulator silicone rubber (WSR) remains a significant challenge. Herein, an efficient alcoholysis strategy for the surface modification of WSR was explored by using nerol as alcoholysis reagent, and then the nerol modified WSR (Nerol-WSR) was utilized in polypropylene toughening. FTIR spectra indicate that nerol can served as nucleophilic reagent to cleave the Si-O bonds in WSR, resulting in an efficient surface grafting of nerol moieties on WSR. The grafting content of nerol moieties gradually increases with alcoholysis times. Morphol. investigation demonstrates that with the increase of alcoholysis time, the dispersion state of Nerol-WSR particles in PP matrix is significantly improved, along with a much smaller particle size. Accordingly, with the addition of 10 weight% of Nerol-WSR, the resulting PP composites can achieve a remarkable increase of approx. 200% in impact strength. This should be due to the grafted nerol moieties can substantially improve the interfacial adhesion of the composites and hence facilitate the dispersion of WSR particles in PP matrix. Therefore, the stress concentration of PP can also be effectively delivered to the adjacent Nerol-WSR and thus retard the propagation of cracks. In addition, the addition of Nerol-WSR can also increase the loss tangent values of the composites, which indicates its potential application in polymer damping.

Journal of Polymer Research published new progress about 106-25-2. 106-25-2 belongs to alcohols-buliding-blocks, auxiliary class Natural product, name is cis-3,7-Dimethyl-2,6-Octadien-1-Ol, and the molecular formula is C3H8N2S, Safety of cis-3,7-Dimethyl-2,6-Octadien-1-Ol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Dharmalingam, K. published the artcileFunctionalization of cellulose-based nanocomposite hydrogel films with zinc oxide complex and grapefruit seed extract for potential applications in treating chronic wounds, Name: 2-(Benzyl(methyl)amino)ethanol, the publication is Polymer (2020), 122620, database is CAplus.

In this study, the influence of grapefruit seed extract (GFSE) was studied on citric acid and zinc oxide incorporated cellulose-based hydrogel films. The effect of GFSE (0.25-1.0%, volume/volume) on hydrogel films was examined for their physico-chem., mech., thermal, antioxidant and antibacterial properties. The swelling ratio, tensile strength and thermal stability of films decreased with increase in GFSE concentrations On the other hand, elongation (%) and antioxidant activity of films were found to be 34-60% and 25-79%, resp. for increasing amounts of GFSE. FESEM and FETEM clearly showed that two different types of nanoparticles (50-90 nm and 5-10 nm) were present in GFSE incorporated films. The release of polyphenolic compounds and zinc from films was in sustained manner. Furthermore, the fabricated hydrogel films exhibited antibacterial activity against both E. coli and S. aureus. All these results indicate that the prepared nanocomposite hydrogel films could find their potential applications in wound healing.

Polymer published new progress about 101-98-4. 101-98-4 belongs to alcohols-buliding-blocks, auxiliary class Amine,Benzene,Alcohol, name is 2-(Benzyl(methyl)amino)ethanol, and the molecular formula is C10H15NO, Name: 2-(Benzyl(methyl)amino)ethanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Chandra, Girish published the artcileImproved synthesis of a DNA-dependent protein kinase inhibitor IC86621, Synthetic Route of 27292-49-5, the publication is Archives of Pharmacal Research (2012), 35(4), 639-645, database is CAplus and MEDLINE.

An improved synthesis of DNA-dependent protein kinase inhibitor IC86621 is described. This developed method provides an easy access to this simple mol. by using amination, acetylation and Fries rearrangement reactions.

Archives of Pharmacal Research published new progress about 27292-49-5. 27292-49-5 belongs to alcohols-buliding-blocks, auxiliary class Morpholine,Benzene,Phenol, name is 3-Morpholinophenol, and the molecular formula is C10H13NO2, Synthetic Route of 27292-49-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts