Zhu, Jiangxiong’s team published research in International Journal of Biological Macromolecules in 2019-06-01 | CAS: 59-23-4

International Journal of Biological Macromolecules published new progress about Glycoproteins Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, HPLC of Formula: 59-23-4.

Zhu, Jiangxiong published the artcileComparison and structural characterization of polysaccharides from natural and artificial Se-enriched green tea, HPLC of Formula: 59-23-4, the main research area is green tea leaf polysaccharide selenium; Artificial Se-enriched tea polysaccharides; Characterization; Natural Se-enriched tea polysaccharides.

Se-enriched green tea has been widely used as a functional food and disease prevention. In this study, two kinds of homogeneous polysaccharides namely ASe-TPS2 and NSe-TPS2 were obtained from artificial and natural Se-enriched teas with the mol. weights of 6.73 × 103 Da and 2.44 × 105 Da. The structures of ASe-TPS2 and NSe-TPS2 were characterized by monosaccharide composition anal., partial acid hydrolysis, methylation, FT-IR spectroscopy, NMR spectroscopy, SEM and TGA anal. It showed that ASe-TPS2 and NSe-TPS2 were acidic polysaccharides containing high amount of uronic acid. The structure of the ASe-TPS2 was mainly composed of β-D-(1 → 3)-Glcp, α-D-(1 → 4)-GalpA, (1 → 4)-Glcp, α-L-(1 → 2)-Rhap and α-D-(1 → 4)-GalpA, and the non-reducing ends were mainly composed of Araf and Xylp. However, the NSe-TPS2 was mainly composed of β-D-(1 → 4)-Glcp and α-D-(1 → 4)-GalpA, and the branches were mainly composed of β-L-(1 → 2)-Araf, α-D-(1 → 3)-Galp and β-L-(1 → 2)-Rhap whereas the non-reducing ends were mainly composed of Glcp and Galp residues. These results suggested that the distinction of selenylation methods could present different polysaccharide chain structures.

International Journal of Biological Macromolecules published new progress about Glycoproteins Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, HPLC of Formula: 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Dalponte Dallabona, Ithiara’s team published research in International Journal of Biological Macromolecules in 2020-11-15 | CAS: 124-76-5

International Journal of Biological Macromolecules published new progress about Anthocyanins Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Quality Control of 124-76-5.

Dalponte Dallabona, Ithiara published the artcileDevelopment of alginate beads with encapsulated jabuticaba peel and propolis extracts to achieve a new natural colorant antioxidant additive, Quality Control of 124-76-5, the main research area is jabuticaba peel propolis extract encapsulation alginate antioxidant additive; Anthocyanins; Plinia cauliflora; Polyphenolics; Scaptotrigona bipunctata.

This work aims to encapsulate anthocyanins and phenolic compounds extracted from a native Brazilian fruit peel – jabuticaba (Plinia cauliflora (Mart.) Kausel) and propolis from Tubuna (Scaptotrigona bipunctata) stingless bees, with great potential benefits for human health. The alginate encapsulation was conducted by the ionotropic gelation through the dripping into the CaCl2 solution Both raw extracts were characterized by TPC – total phenolic content (Folin-Ciocalteu), AA -antioxidant activity (DPPH and ABTS assays), and TMAC – total monomeric anthocyanin concentration (pH differential method); as well as their resultant mixture (2:1 jabuticaba/propolis). The obtained beads presented highly efficient encapsulation of total polyphenols (∼98%) and monomeric anthocyanins (∼89%), with spherical morphol. and smooth surface obtaining a mean diameter between 200 and 250μm. In vitro release study showed that JPE/alginate beads were completely disintegrated at pH 7.4 (intestinal pH), but they were resistant to gastric pH (1.2) presenting a slow release of about 40% in 240 min. This is the first report that encapsulates the mixture of jabuticaba and propolis extracts and may contribute to the utilization of a great source of bioactive compounds besides the potential pigment of anthocyanins, an alternative to natural and healthy food/beverage colorants.

International Journal of Biological Macromolecules published new progress about Anthocyanins Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Quality Control of 124-76-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Rys, Magdalena’s team published research in Molecules in 2022 | CAS: 124-76-5

Molecules published new progress about Carbohydrates Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, HPLC of Formula: 124-76-5.

Rys, Magdalena published the artcileBio-Herbicidal Potential of Nanoemulsions with Peppermint Oil on Barnyard Grass and Maize, HPLC of Formula: 124-76-5, the main research area is peppermint oil barnyard grass maize bioherbicidal nanoemulsions; Chlorophyll a fluorescence; Eco-Polysorbate 80; FT-Raman spectroscopy; isothermal calorimetry; phytotoxicity; polydispersity index; relative water content.

Bio-based nanoemulsions are part of green pest management for sustainable agriculture. This study assessed the physicochem. properties and the herbicidal activities of the peppermint essential oil nanoemulsions (PNs) in concentrations 1.0-10% stabilized by Eco-Polysorbate 80 on germinating seeds and young plants of maize and barnyard grass. Based on the design of experiment (DOE) results, the final nanoemulsion formulations were obtained with 1, 1.5, 2, and 5% of essential oil concentration Biol. analyses were conducted to select the most promising sample for selective control of barnyard grass in maize. Seedlings growing in the presence of PNs displayed an overall inhibition of metabolism, as expressed by the calorimetric analyses, which could result from significant differences in both content and composition of carbohydrates. Concentration-response sub estimation showed that leaf-sprayed concentration of PN causing 10% of maize damage is equal to 2.2%, whereas doses causing 50% and 90% of barnyard grass damage are 1.1% and 1.7%, resp. Plants sprayed with PN at 5% or 10% concentration caused significant drops in relative water content in leaves and Chlorophyll a fluorescence 72 h after spraying. In summary, peppermint nanoemulsion with Eco-Polysorbate 80 at 2% concentration is a perspective preparation for selective control of barnyard grass in maize. It should be analyzed further in controlled and field conditions.

Molecules published new progress about Carbohydrates Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, HPLC of Formula: 124-76-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhu, Jiangxiong’s team published research in International Journal of Biological Macromolecules in 2020-07-01 | CAS: 59-23-4

International Journal of Biological Macromolecules published new progress about Carbohydrates Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Name: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal.

Zhu, Jiangxiong published the artcileComparative analysis of existence form for selenium and structural characteristics in artificial selenium-enriched and synthetic selenized green tea polysaccharides, Name: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, the main research area is artificial selenium enriched green tea polysaccharide; Artificial selenium-enriched tea polysaccharides; Structure characteristics; The form with selenium.

This study aimed to investigate the activity, structural characterization and present forms of selenium in two different artificial selenium-enriched tea polysaccharides (Se-TPS). The physicochem. anal. showed that both CSe-tps1 and ASe-tps1 were acidic heteropolysaccharides with different monosaccharide composition, molar ratio, and selenium content. Structural investigations including FT-IR, Raman spectra and 1D, 2D NMR anal. revealed that selenium in CSe-tps1 replaced the hydroxyl group at the C-6 position in the polysaccharide with the form of selenyl ester, while most of the selenium in ASe-tps1 replaced the hydroxyl group at the C-1 and C-6 position in the form of the Se-H bond on the branch of the polysaccharide. Besides, a series of studies on the structural characteristics of the Congo red test, I2-KI reaction, FESEM, DSC, and XRD anal. showed that the two artificial Se-TPSs had a triple helix structure and more branches. However, there were significant differences in crystal morphol., apparent morphol., heat release ability, and the α-glucosidase inhibition activity. These results indicated that the difference in artificial selenization methods not only made the polysaccharide exhibit different structural characteristics and the hypoglycemic activity, but also had a significant effect on the form of selenium in polysaccharides.

International Journal of Biological Macromolecules published new progress about Carbohydrates Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Name: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Song, Qianqian’s team published research in International Journal of Biological Macromolecules in 2019-10-01 | CAS: 59-23-4

International Journal of Biological Macromolecules published new progress about Carbohydrates Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Recommanded Product: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal.

Song, Qianqian published the artcilePhysicochemical and functional properties of a water-soluble polysaccharide extracted from Mung bean (Vigna radiate L.) and its antioxidant activity, Recommanded Product: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, the main research area is Vigna water soluble polysaccharide hydration oil holding capacity antioxidant; Antioxidant; Functional properties; Mung bean; Physicochemical characterization; Polysaccharide.

A water-soluble polysaccharide (MBP-1) was isolated from Mung bean (Vigna radiate L.) and its physicochem. characterization, functional properties, and antioxidant activity was investigated. Chem. anal. revealed that the contents of carbohydrate, uronic acid, and protein were 33.05 ± 0.10%, 25.83 ± 0.04%, and 3.17 ± 0.36%, resp. The mol. weight (Mw) of MBP-1 was 146.22 kDa and it was consist of arabinose (Ara), glucose (Glc), xylose (Xyl), galactose (Gal), and galacturonic acid (GlcA) in a molar ratio of 0.94:0.37:0.33:0.13:5.99. The results of X-ray diffractometry (XRD) and thermal gravimetric anal. (TGA) indicated MBP-1 was semi-crystalline material with better thermal stability. MBP-1 exhibited good hydration properties and oil holding capacity. In addition, the antioxidant assay results showed MBP-1 had high 1,1-Diphenyl-2-picrylhydrazylradical (DPPH) and hydroxyl radical scavenging activities with concentration for 50% of maximal effect (EC50) of 1.59 and 0.51 mg/mL. Overall, these results indicated that MBP-1 presents a promising natural source of food additive or antioxidant.

International Journal of Biological Macromolecules published new progress about Carbohydrates Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Recommanded Product: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wang, Xiaojiang’s team published research in International Journal of Biological Macromolecules in 2019-07-01 | CAS: 59-23-4

International Journal of Biological Macromolecules published new progress about Carbohydrates Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Name: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal.

Wang, Xiaojiang published the artcileExtraction, isolation and structural characterization of a novel polysaccharide from Cyclocarya paliurus, Name: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, the main research area is Cyclocarya pectin polysaccharide physicochem property; Cyclocarya paliurus; Highly-branched polysaccharide; Mass spectrometry; Oligosaccharide sequence; Structural characterization.

A water soluble polysaccharide CP-III was extracted and purified from Cyclocarya paliurus. CP-III is identified as a novel pectin-like polysaccharide with mol. weight (Mw) of 72.7 kDa. The structural features of CP-III were characterized by methylation and NMR (NMR) spectroscopy. Its depolymerized fragments were analyzed by hydrophilic interaction chromatog.-Fourier transform mass spectrometry (HILIC-FTMS). The main chain of CP-III is composed of →4)GalAp(α1 → and →2)Rhap(α1 → 4)GalAp(α1→, repeatedly. The residue of →4)Galp(β1 → and →5)Araf(α1 → alternately exists on the O-4 of partial →2)Rhap(α1 → residues as side chains. On the O-3 of sectional →5)Araf(α1 → residues is a secondary branch assembled by →3)Araf(α1→. Moreover, on the non-reducing terminus of →4)Galp(β1 → occasionally have an →5)Araf(α1 → chain. Surprisingly, a sub-branch constructed by →6)Hexp(β1 → with a galacturonate or Me galacturonate exists on the O-3 of certain →4)Galp(β1 → residues in the non-reducing terminus. In addition, a terminal Xyl is located on the O-3 of fractional →4)GalAp(β1 → residue. The highly branched polysaccharide CP-III with high water solubility can be used as food supplement and medicinal carrier in the future.

International Journal of Biological Macromolecules published new progress about Carbohydrates Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Name: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Min, Wei-Hong’s team published research in Journal of Bioscience and Bioengineering in 2019-06-30 | CAS: 59-23-4

Journal of Bioscience and Bioengineering published new progress about Carbohydrates Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, HPLC of Formula: 59-23-4.

Min, Wei-Hong published the artcileCharacterization and antioxidant activity of an acidic exopolysaccharide from Lactobacillus plantarum JLAU103, HPLC of Formula: 59-23-4, the main research area is Lactobacillus exopolysaccharide antioxidant oxygen radical absorbance capacity; Antioxidant activity; Exopolysaccharide; Lactobacillus plantarum; Oxygen radical absorbance capacity; Purification.

An acidic exopolysaccharide (EPS) designated as EPS103 was isolated, purified and characterized from Lactobacillus plantarum JLAU103. EPS103 had a relatively lower mol. weight of 12.4 KDa and was consisted of arabinose, rhamnose, fucose, xylose, mannose, fructose, galactose, and glucose in an approx. molar ratio of 4.05: 6.04: 6.29: 5.22: 1.47: 5.21: 2.24: 1.83. A specific spectrogram of acidic polysaccharide was obtained by FT-IR anal., and both α- and β-type configurations were presented in EPS103 based on the NMR spectroscopy. Microstructural anal. of EPS103 demonstrated a smooth and glittering cube structure, and presence of many homogeneous rod-shaped lumps. Comprehensive study of in vitro antioxidant activity indicated that EPS103 possess strong scavenging abilities against hydroxyl, ABTS, and DPPH radicals with the maximum of 80.4%, 65.5%, and 60.5%, resp., at 10 mg/mL concentration Furthermore, EPS103 also showed strong ferrous ions chelating activity and oxygen radical absorbance capacity. These results together indicated that the EPS103 isolated from L. plantarum JLAU103 has great potential for use as a natural antioxidant or functional additive in foods industry.

Journal of Bioscience and Bioengineering published new progress about Carbohydrates Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, HPLC of Formula: 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Hua, Mei’s team published research in Food Chemistry in 2019-07-15 | CAS: 59-23-4

Food Chemistry published new progress about Carbohydrates Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Application In Synthesis of 59-23-4.

Hua, Mei published the artcileStructure, physicochemical properties and adsorption function of insoluble dietary fiber from ginseng residue: A potential functional ingredient, Application In Synthesis of 59-23-4, the main research area is insoluble dietary fiber ginseng residue adsorption; Adsorption function; Composition; Ginseng residues; Insoluble dietary fiber; Physicochemical properties; Structure.

The insoluble dietary fiber from ginseng residue (ginseng-IDF) was extracted using the AOAC (Association of Official Anal. Chemists) method with content of 68.61%. Ginseng-IDF had a polysaccharide content of 18.87%, uronic acid content of 7.85%, protein content of 6.52%, and had ideal water-holding capacity (17.66 g/g), swelling ability (15.05 mL/g), and oil-holding capacity (1.78 g/g). Scanning electron microscope, Fourier transform IR spectroscopy, and X-ray diffraction analyses suggested that ginseng-IDF had the typical structures of hydrolysis fiber, polysaccharide functional groups, and crystal structure of cellulose. Different fiber components give ginseng-IDF a specified range of pyrolysis temperature, and it is suitable for application in food processing lower than 300 °C. In addition, ginseng-IDF exhibited notable glucose and sodium cholate adsorption, significantly improved nitrite adsorption at pH 2.0 and cholesterol adsorption at pH 7.0. The above results show that ginseng-IDF could be used as an ideal functional ingredient in food processing.

Food Chemistry published new progress about Carbohydrates Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Application In Synthesis of 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Huang, Fei’s team published research in Carbohydrate Polymers in 2019-02-15 | CAS: 59-23-4

Carbohydrate Polymers published new progress about Carbohydrates Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Application In Synthesis of 59-23-4.

Huang, Fei published the artcilePhysicochemical properties and prebiotic activities of polysaccharides from longan pulp based on different extraction techniques, Application In Synthesis of 59-23-4, the main research area is prebiotic polysaccharide longan extraction sugar viscosity solubility; Different extraction methods; Glycosidic linkage; Longan polysaccharides; Probiotic proliferation.

Longan pulp polysaccharides were extracted with hot water (LP-H), superfine grinding (LP-S) and superfine grinding-assisted enzymic treatments (LP-SE). The yields, physicochem. properties and prebiotic activities of polysaccharides were investigated. Compared with LP-H and LP-S, the yield, sugar content, solubility, arabinose and mannose percentage of LP-SE increased while its apparent viscosity, particle size, Mw and glucose percentage declined. Three LPs contained similar glycosidic linkage of →3)-α-L-Araf-(1→, →3,6)-β-D-Galp-(1→ and α-L-Rhap(l→, while they each contained specific glycosidic linkage of →4)-β-D-Glcp(l→, →4)-β-D-Galp-(1→ and →5)-α-L-Araf-(1→ in LP-H, LP-S and LP-SE, resp. Moreover, LP-SE exhibited stronger stimulation than LP-H and LP-S on the proliferation of Lactobacillus plantarum, Lactobacillus bulgaricus, Lactobacillus fermentum and Leuconostoc mesenteroides. The results indicated three extraction methods had some effect on chem. composition and structure of polysaccharide. LP-SE extracted by superfine grinding-assisted enzymic treatment exhibited the highest prebiotic activities, which have a great potential in applying in functional food and medical industry.

Carbohydrate Polymers published new progress about Carbohydrates Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Application In Synthesis of 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Haskovic, Minela’s team published research in Journal of Inherited Metabolic Disease in 2020 | CAS: 59-23-4

Journal of Inherited Metabolic Disease published new progress about Carbohydrates Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, HPLC of Formula: 59-23-4.

Haskovic, Minela published the artcilePathophysiology and targets for treatment in hereditary galactosemia: A systematic review of animal and cellular models, HPLC of Formula: 59-23-4, the main research area is review carbohydrate metabolism galactose uridine diphosphate galactosemia; animal models; cellular models; hereditary galactosemia; pathophysiology; treatment targets.

Since the first description of galactosemia in 1908 and despite decades of research, the pathophysiol. is complex and not yet fully elucidated. Galactosemia is an inborn error of carbohydrate metabolism caused by deficient activity of any of the galactose metabolising enzymes. The current standard of care, a galactose-restricted diet, fails to prevent long-term complications. Studies in cellular and animal models in the past decades have led to an enormous progress and advancement of knowledge. Summarising current evidence in the pathophysiol. underlying hereditary galactosemia may contribute to the identification of treatment targets for alternative therapies that may successfully prevent long-term complications. A systematic review of cellular and animal studies reporting on disease complications (clin. signs and/or biochem. findings) and/or treatment targets in hereditary galactosemia was performed. PubMed/MEDLINE, EMBASE, and Web of Science were searched, 46 original articles were included. Results revealed that Gal-1-P is not the sole pathophysiol. agent responsible for the phenotype observed in galactosemia. Other currently described contributing factors include accumulation of galactose metabolites, uridine diphosphate (UDP)-hexose alterations and subsequent impaired glycosylation, endoplasmic reticulum (ER) stress, altered signalling pathways, and oxidative stress. galactokinase (GALK) inhibitors, UDP-glucose pyrophosphorylase (UGP) up-regulation, uridine supplementation, ER stress reducers, antioxidants and pharmacol. chaperones have been studied, showing rescue of biochem. and/or clin. symptoms in galactosemia. Promising co-adjuvant therapies include antioxidant therapy and UGP up-regulation. This systematic review provides an overview of the scattered information resulting from animal and cellular studies performed in the past decades, summarising the complex pathophysiol. mechanisms underlying hereditary galactosemia and providing insights on potential treatment targets.

Journal of Inherited Metabolic Disease published new progress about Carbohydrates Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, HPLC of Formula: 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts