Tag: M.W=150-200

Chu, Lulu published the artcileChemical composition, antioxidant activities of polysaccharide from Pine needle (Pinus massoniana) and hypolipidemic effect in high-fat diet-induced mice, Synthetic Route of 59-23-4, the main research area is Pinus needle polysaccharide antioxidant hypolipidemic high fat diet; Antioxidant activities; Chemical composition; Hypolipidemic effect; Pine needle polysaccharide.

The aim of this study is to investigate hypolipidemic and antioxidant effects of Pine needle polysaccharide (PNP) from Pinus massoniana in high-fat diet (HFD)-induced mice. PNP could significantly improve the serum lipid levels (total cholesterol, triacylglycerols, high-d. lipoprotein cholesterol, low-d. lipoprotein cholesterol), enhance the antioxidant enzymes levels (total antioxidant capability, superoxide dismutase, glutathione peroxidase, catalase), and decrease malondialdehyde (MDA) content in HFD-induced mice. PNP exhibited distinct antioxidant ability on the superoxide anions, 1, 1-diphenyl-2-picrylhydrazyl (DPPH) and ferric ion reducing antioxidant power (FRAP) in vitro. The average mol. weight (Mw) of PNP was 6.17 × 105 Da, and mainly of fucose, arabinose, galactose, glucose, galacturonic acid. These results suggested that PNP might be used as functional foods and natural drugs in enhancing antioxidant ability and alleviating the hyperlipidemia.

International Journal of Biological Macromolecules published new progress about Blood lipids Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Synthetic Route of 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Inokuchi, Tsutomu published the artcileElectroreductive ring-opening of α,β-epoxy carbonyl compounds and their homologs through recyclable use of diphenyl diselenide or diphenyl ditelluride as a mediator, Product Details of C10H20O2, the main research area is electrochem ring cleavage epoxy carbonyl compound; aldol; hydroxy ketone; nitrile hydroxy; ester hydroxy; regiochem reduction cleavage epoxy carbonyl.

A novel access to β-hydroxy carbonyl compounds from the corresponding α,β-epoxy carbonyl compounds is attained by the recyclable use of Ph2Se2 or Ph2Te2 as an electroreduction mediator in a MeOH-NaClO4-Pt system. α,β-Epoxy ketones are converted to the corresponding aldols in the presence of malonic esters. Similarly, α,β-epoxy esters and nitriles are reduced to the corresponding β-hydroxy compounds in the presence of AcOH.

Journal of Organic Chemistry published new progress about Carboxylic acids, epoxy, esters Role: RCT (Reactant), RACT (Reactant or Reagent). 42822-86-6 belongs to class alcohols-buliding-blocks, name is 2-(2-Hydroxypropan-2-yl)-5-methylcyclohexanol, and the molecular formula is C10H20O2, Product Details of C10H20O2.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

De Almeida E Silva, Beatriz published the artcileInteraction between mycorrhizal fungi and Meloidogyne javanica on the growth and essential oil composition of basil (Ocimum basilicum), Quality Control of 124-76-5, the main research area is Meloidogyne Ocimum mycorrhizal fungi essential oils.

Plant-parasitic nematodes and arbuscular mycorrhizal fungi (AMF) have been reported to alter the yield and chem. composition of basil (Ocimum basilicum) essential oil. The aim of this study was to evaluate the effectiveness of AMF to control the root-knot nematode Meloidogyne javanica in basil and to investigate the effects of nematode-AMF interactions on plant growth, phosphorus (P) absorption, and essential oil composition The experiment was conducted under greenhouse conditions following a completely randomized 3 x 2 factorial (two fungal species and an uninoculated control x inoculated and uninoculated seedlings) arrangement with 10 replicates. Substrates were inoculated with Claroideoglomus etunicatum, Rhizophagus clarus, or no fungi (control) and sown with basil seeds. After 20 days, half of the seedlings were inoculated with 4,000 M. javanica eggs. After 60 days, the vegetative parameters, P absorption, essential oil composition, nematode population d., AMF root-colonization efficiency, and AMF spore d. were determined The presence of AMF increased the basil’s fresh weight and ability to absorb P, while reducing the M. javanica reproduction In total, 21 compounds were identified in basil essential oil, the concentrations of which varied according to the treatments. The major components were eucalyptol, linalool, eugenol, β-elemene, trans-α-bergamotene, and τ-cadinol. Inoculation with AMF decreased the linalool levels but increased the amount of eucalyptol. Mycorrhizal plants showed increased shoot height, P uptake, and essential oil yield and a decreased nematode population d. in their roots.

Australian Journal of Crop Science published new progress about Chlorophylls Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Quality Control of 124-76-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Flamini, Guido published the artcileEssential oil composition of Salvia rosmarinus spenn. wild samples collected from six sites and different seasonal periods in Elba Island (Tuscan Archipelago, Italy), Synthetic Route of 124-76-5, the main research area is Salvia essential oil 18cineole camphene seasonal climate statistical analysis; 18-cineole; borneol; camphor; geographic origin; statistical analysis; α-pinene.

The hydrodistd. essential oils from eighteen samples of Salvia rosmarinus Spenn. collected in six localities of Elba Island (Tuscany, Italy) during three different seasonal periods were analyzed by GC-MS for the first time. Fifty-five components were identified, representing 96.8-99.6% of the total chem. composition All the tested essential oils were characterized by a high content of monoterpenes (oxygenated 49.2-80.3%; hydrocarbons 18.7-48.3%). Among them, 1,8-cineole (26.4-49.1%), α-pinene (4.5-34.8%), camphor (1.1-18.8%) and borneol (1.7-16.2%) were the main constituents. The high amount of 1,8-cineole/α-pinene/camphor/borneol may suggest the presence of an intermediate rosemary chemotype. Statistical anal. was also performed on the essential oil (EO) composition evidenced an expected difference depending on the collection seasons, to the geog. areas and soil composition A comparison with the essential oil composition from S. rosmarinus collected in all the other islands of Tuscan Archipelago (Italy) was also reported, together with a Multivariate Statistical Anal.

Natural Product Research published new progress about Essential oils Role: THU (Therapeutic Use), BIOL (Biological Study), USES (Uses). 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Synthetic Route of 124-76-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Gao, Chao published the artcileUnique Binding Specificities of Proteins toward Isomeric Asparagine-Linked Glycans, Synthetic Route of 59-23-4, the main research area is asparagine Nglycan Siglec protein structure influenza virus infection; N-glycan isomer; N-glycan-binding specificity; chemoenzymatic synthesis; glycan-binding proteins; glycosyltransferases; microarray.

The glycan ligands recognized by Siglecs, influenza viruses, and galectins, as well as many plant lectins, are not well defined. To explore their binding to asparagine (Asn)-linked N-glycans, we synthesized a library of isomeric multiantennary N-glycans that vary in terminal non-reducing sialic acid, galactose, and N-acetylglucosamine residues, as well as core fucose. We identified specific recognition of N-glycans by several plant lectins, human galectins, influenza viruses, and Siglecs, and explored the influence of sialic acid linkages and branching of the N-glycans. These results show the unique recognition of complex-type N-glycans by a wide variety of glycan-binding proteins and their abilities to distinguish isomeric structures, which provides new insights into the biol. roles of these proteins and the uses of lectins in biol. applications to identify glycans.

Cell Chemical Biology published new progress about Agglutinins Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Synthetic Route of 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Gao, Xiong published the artcileStructural characterization and immunomodulatory activity of a water-soluble polysaccharide from Ganoderma leucocontextum fruiting bodies, Recommanded Product: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, the main research area is water soluble polysaccharide Ganoderma fruiting body; Ganoderma leucocontextum; Immunostimulatory activity; Polysaccharide; Structure; Toll-like receptor 2.

Ganoderma leucocontextum is a new species of Ganoderma discovered in 2014. Up to now, the structural characteristics and immunoregulatory activity of its polysaccharides remain virtually unknown. In this study, a water-soluble polysaccharide termed, GLP-3, was purified from G. leucocontextum by ultrafiltration and column chromatog. The results revealed that GLP-3 mainly consisted of glucose (92.7%) and its weight average mol. weight was 159.7 kDa. The structural anal. indicated that the backbone of GLP-3 was →4-α-D-Glcp-(1→4,6)-β-D-Glcp-1→ with a β-Glcp-1→ branch. Atomic force microscopy and Congo red experiments revealed that GLP-3 might possess a globular structure with triple-helix conformation in water. Moreover, GLP-3 was recognized by toll-like receptor 2 (TLR2) and exerted immunomodulatory effects via activating mitogen-activated protein kinases (MAPKs), phosphatidylinositol-3-kinase (PI3K)/Akt and nuclear factor-κB (NF-κB) signaling pathways in RAW 264.7 macrophages. Collectively, these results suggested that GLP-3 could be developed as a potential functional food ingredient for immunomodulation.

Carbohydrate Polymers published new progress about Carbohydrates Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Recommanded Product: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Mutaillifu, Paiheerding published the artcileStructural characterization and antioxidant activities of a water soluble polysaccharide isolated from Glycyrrhiza glabra, Related Products of alcohols-buliding-blocks, the main research area is Glycyrrhiza GPN polysaccharide antioxidant activity glycosidic bond water solubility; 1,4-Linked α-D-Glcp; Antioxidant activity; Glycyrrhiza glabra; Water soluble polysaccharide.

A water-soluble polysaccharide, named GPN, with mol. mass 38.7 kDa was isolated from Glycyrrhiza glabra with hot water extraction, ethanol precipitation, and purified by column chromatog. Monosaccharide composition anal. confirmed the presence of predominant glucose (98.03%) and trace amount of mannose, arabinose, and galactose. Methylation and GC-MS anal. revealed that the main glycosidic bonds in GPN comprised 1,4-linked Glcp, T-linked Glcp, 1,4,6-linked Glcp, and 1,6-linked Glcp. Based on these results and 1D/2D NMR spectroscopy, GPN has a linear backbone of 1,4-linked α-D-Glcp and 1,6-linked α-D-Glcp which substituted at C-4 of glucose. The side chain probably composed from 1,4-linked to main side α-D-Glcp and terminal 1-linked β-D-Glcp to the C-3 of D residue. Congo red assay confirmed the existence of triple helix structure. Moreover, SEM and XRD anal. revealed that the GPN had irregular fibrous, filaments like surface; and both crystalline and amorphous structure. GPN also displayed favorable thermal stability. Moreover, G.glabra polysaccharide showed good antioxidant activity.

International Journal of Biological Macromolecules published new progress about Carbohydrates Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Related Products of alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhang, Bo published the artcileEndogenous calcium attenuates the immunomodulatory activity of a polysaccharide from Lycium barbarum L. leaves by altering the global molecular conformation, Computed Properties of 59-23-4, the main research area is Lycium leaf macrophage calcium heteropolysaccharide immunomodulation; Conformation; FTIR; Goji; Macrophage; Mannose; Uronic acid.

A heteropolysaccharide, LP5, was purified from Lycium barbarum L. leaves. It was identified as a calcium-rich polysaccharide (8.6 mg calcium/g) with a mol. weight of 2.50 × 105 Da. The polysaccharide was composed of six kinds of monosaccharides, of which mannose and xylose are the main components. And it contains 16.37% glucuronic acid. Studies on RAW264.7 cells demonstrated that this polysaccharide exhibited potent immunomodulatory activity, including an increase in phagocytic activity, as well as the release of both nitric oxide and cytokines. However, after the depletion of calcium, the polysaccharide exhibited greater immunomodulatory activity (p < 0.05). Further conformation anal. confirmed that the polysaccharide changed from a compact spherical conformation to a random coil structure in aqueous solution after the depletion of calcium, which resulted in increased immunomodulatory activity by LP5. International Journal of Biological Macromolecules published new progress about Carbohydrates Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Computed Properties of 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Park, Hye-Ryung published the artcileSignaling pathway and structural features of macrophage-activating pectic polysaccharide from Korean citrus, Cheongkyool peels, Name: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, the main research area is Cheongkyool peel macrophage pectic polysaccharide signaling; Cheongkyool; MAPK; NF-κB; Polysaccharide; Rhamnogalacturonan-I.

To characterize the immuno-stimulating ingredient from the Korean citrus, Cheongkyool, a crude polysaccharide (CCE-0) was isolated from the pectinase digests of Cheongkyool peels, from which the complex polysaccharide CCE-I was purified to homogeneity by gel filtration. CCE-I highly enhanced the production of IL-6, TNF-α, and NO in RAW 264.7 cell lines. It augmented the mRNA expression of IL-6, TNF-α, and iNOS in a dose-dependent manner. Moreover, CCE-I dose-dependently induced phosphorylation of MAPKs and NF-κB related proteins and led to the nuclear translocation of p65. The effect of CCE-I on NO and IL-6 production was suppressed by treatment with specific antibodies for TLR2, TLR4, and scavenger receptors. Conversely, the primary structure of CCE-I that exhibited potent immunostimulatory activity was characterized by sugar composition, linkage anal., and oligosaccharide anal. after β-elimination. The results suggested that CCE-I may be a rhamnogalacturonan-I type, highly branched polysaccharide with short arabinan and galactan side chains.

International Journal of Biological Macromolecules published new progress about CD14 antigens Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Name: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Priestley, C. M. published the artcileLethality of essential oil constituents towards the human louse, Pediculus humanus, and its eggs, Recommanded Product: 2-(2-Hydroxypropan-2-yl)-5-methylcyclohexanol, the main research area is insecticide ovicide essential oil Pediculus humanus.

Essential oils have been widely used in traditional medicine for the eradication of lice, including head lice, but due to the variability of their constitution the effects may not be reproducible. In an attempt to assess the contribution of their component monoterpenoids, a range of common individual compounds were tested in in vitro toxicity model against both human lice (Pediculus humanus, an accepted model of head lice lethality) and their eggs, at different concentrations No detailed study into the relative potencies of their constituent terpenoids has so far been published. Adult lice were observed for lack of response to stimuli over 3 h and the LT50 calculated, and the percentage of eggs failing to hatch was used to generate ovicidal activity data. A ranking was compiled for adult lice and partially for eggs, enabling structure-activity relationships to be assessed for lethality to both, and showed that, for activity in both life-cycle stages, different structural criteria were required. (+)-Terpinen-4-ol was the most effective compound against adult lice, followed by other mono-oxygenated monocyclic compounds, whereas nerolidol was particularly lethal to eggs, but ineffective against adult lice.

Fitoterapia published new progress about Essential oils Role: AGR (Agricultural Use), BIOL (Biological Study), USES (Uses). 42822-86-6 belongs to class alcohols-buliding-blocks, name is 2-(2-Hydroxypropan-2-yl)-5-methylcyclohexanol, and the molecular formula is C10H20O2, Recommanded Product: 2-(2-Hydroxypropan-2-yl)-5-methylcyclohexanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts