Tag: M.W=100-150

Yu, Wangzhi published the artcilePalladium-Catalyzed Linear Hydrothiocarbonylation of Unactivated Terminal Alkenes: Synthesis of Aliphatic Thioesters, Name: 2-Phenylethanethiol, the publication is Organic Letters, database is CAplus and MEDLINE.

A Pd-catalyzed hydrothiocarbonylation of unactivated terminal alkenes is presented. According to this protocol, aliphatic thioesters were synthesized with exclusive linear selectivity under mild reaction conditions. Good to excellent yields (up to 91% yield), broad substrate scope, broad functional group tolerance, and utility of the method demonstrated the advantages of this protocol.

Organic Letters published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C29H24FN7O, Name: 2-Phenylethanethiol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Jeon, Mina published the artcileTransformation of Silanes into Silanols using Water and Recyclable Metal Nanoparticle Catalysts, Name: Triethylsilanol, the publication is ChemCatChem (2012), 4(4), 521-524, database is CAplus.

The highly selective and efficient transformation of organosilanes into silanols was achieved using readily available heterogeneous metal nanoparticle catalysts on an Al oxyhydroxide support [M/AlO(OH), M = Pd, Au, Rh, Ru, and Cu]. The transformation was performed under ambient conditions with H₂O. Among the catalysts studied, the Pd catalyst showed the highest activity; it was highly recyclable and applicable for large-scale reactions. The Pd catalyst was effective for a wide range of silanes, although small amounts of hydrogenated side products were formed in some cases for alkynyl silanes. The hydrogenation reaction was suppressed by using an O atm. or by using a gold catalyst. The Au catalyst could be reused at least ten times without any loss in activity.

ChemCatChem published new progress about 597-52-4. 597-52-4 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is Triethylsilanol, and the molecular formula is C6H16OSi, Name: Triethylsilanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Chen, Xincheng published the artcileTheoretical study on the reaction of Et₃GeCH:CH₂ with Et₃SiOH, Recommanded Product: Triethylsilanol, the publication is Advanced Materials Research (Durnten-Zurich, Switzerland) (2012), 301-304, database is CAplus.

The reaction of Et₃GeCH:CH₂ + Et₃SiOH → Et₃SiO-Ge-Et₃ + CH₂:CH₂ has been studied using quantum chem. methods. Geometries of reactants, transition states, and products have been optimized resp. at the B3LYP/6-311+g(2d,2p) level. The rate constants were evaluated using canonical variational transition state theory (CVT) and canonical variational transition state theory with small-curvature tunneling contributions (CVT/SCT) over the temperature range of 200-3500K. The CVT/SCT rate constants exhibit typical non-Arrhenius behavior, and a three-parameter rate-temperature formula has been fitted as follows: k(T)=1.43 × 10^-38T^5.41exp(-13200/T) (in units of cm³ mol.^-1s^-1).

Advanced Materials Research (Durnten-Zurich, Switzerland) published new progress about 597-52-4. 597-52-4 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is Triethylsilanol, and the molecular formula is C6H16OSi, Recommanded Product: Triethylsilanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Gomola, Kinga published the artcileAn optically uniaxial antiferroelectric smectic phase in asymmetrical bent-core compounds containing a 3-aminophenol central unit, Formula: C7H9NO, the publication is Journal of Materials Chemistry (2010), 20(37), 7944-7952, database is CAplus.

Two series of asym. bent-core compounds possessing 3-aminophenol and its N-Me derivative have been synthesized. The asymmetry arose from the different linkages between the central unit and the chem. chains of the substituents, and in two cases also from different lateral substituents. The mesomorphic properties were investigated by differential scanning calorimetry, polarizing optical microscopy, switching current and electro-optical measurements, X-ray anal., and second-harmonic generation. All materials possessing 3-aminophenol as a central unit showed liquid crystalline properties, and two of them exhibited the orthogonal smectic phase (SmA family phase) and very stable columnar phases, while the N-Me analogs exhibited no mesophase. Because of the optically uniaxial nature, double switching current peaks, and SHG activity associated with a distinct threshold elec. field, this orthogonal smectic phase was assigned to a novel type, which has a short-range antiferroelec. order with a long-range randomized polar plane (SmAP_AR).

Journal of Materials Chemistry published new progress about 14703-69-6. 14703-69-6 belongs to alcohols-buliding-blocks, auxiliary class Amine,Benzene,Phenol, name is 3-(Methylamino)phenol, and the molecular formula is C7H9NO, Formula: C7H9NO.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Huang, Pingsheng published the artcileFluorine Meets Amine: Reducing Microenvironment-Induced Amino-Activatable Nanoprobes for ¹⁹F-Magnetic Resonance Imaging of Biothiols, SDS of cas: 2240-88-2, the publication is ACS Applied Materials & Interfaces (2018), 10(22), 18532-18542, database is CAplus and MEDLINE.

¹⁹F-magnetic resonance imaging (MRI) is of great significance for noninvasive imaging and detection of various diseases. However, the main obstacle in the application of ¹⁹F-MRI agents stems from the unmet signal sensitivity due to the poor water solubility and restricted mobility of segments with high number of fluorine atoms. Herein, the authors report a kind of intracellular reducing microenvironment-induced amino-activatable ¹⁹F-MRI nanoprobe, which can be used for specific imaging of biothiols. In principle, the nanoprobe has an initial architecture of hydrophobic core, where the trifluoromethyl-containing segments are compactly packed and ¹⁹F NMR/MRI signals are quenched (“OFF” state). Upon encountering sulfydryl, the strong electron-withdrawing 2,4-dinitrobenzenesulfonyl groups are excised to recover secondary amino groups, whose pK_a is 7.21. As a consequence, the mol. weight loss of the hydrophobic segment and the protonation of amino groups induce significant disturbance of hydrophilic/hydrophobic balance, leading to the disassembly of the nanoprobes and regain of spin-spin relaxation and ¹⁹F NMR/MRI signals (“ON” state, T₂ up to 296 ± 5.3 ms). This nanoprobe shows high sensitivity and selectivity to biothiols, enabling intracellular and intratumoral imaging of glutathione. The authors’ study not only provides a new nanoprobe candidate for biothiols imaging in vivo but also a promising strategy for the mol. design of real water-soluble and highly sensitive ¹⁹F-MRI nanoprobes.

ACS Applied Materials & Interfaces published new progress about 2240-88-2. 2240-88-2 belongs to alcohols-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Aliphatic hydrocarbon chain,Alcohol, name is 3,3,3-Trifluoropropan-1-ol, and the molecular formula is C3H5F3O, SDS of cas: 2240-88-2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Zhu, Cheng published the artcileKinetics of nitrogen-, oxygen- and sulfur-containing compounds hydrotreating during co-processing of bio-crude with petroleum stream, Recommanded Product: 4-Propylphenol, the publication is Applied Catalysis, B: Environmental (2022), 121197, database is CAplus.

The rational selection of catalysts and process parameters for co-processing biomass- and waste-derived bio-crudes with petroleum streams requires detailed reaction networks and kinetics of the conversion of heteroatom-containing compounds existed in both kinds of feedstocks. We provide the kinetics and reaction networks for the hydrotreating of N,N-diethyldodecanamide and N-methyldodecanamide, model compounds of major components in bio-crudes from hydrothermal liquefaction of wet waste. Their conversion undergoes via two pathways over sulfided NiMo/Al₂O₃ catalyst: deoxygenation followed by denitrogenation of the amine intermediate (DO pathway), and denitrogenation followed by deoxygenation of the alkanol intermediate (DN pathway)-with the DO pathway dominant over the DN pathway. H2S inhibits the deoxygenation step and promotes the denitrogenation step in the DO pathway. The amine intermediate inhibits the amide conversion, with weaker effects on the conversion of secondary amide than on the tertiary amide. The kinetics of hydrotreating of several model compounds representing the main species during co-processing indicate that the removal of nitrogenous species, which are in large quantities and of varying structures, remains the main challenge (compared with S- and O-removal) for co-processing.

Applied Catalysis, B: Environmental published new progress about 645-56-7. 645-56-7 belongs to alcohols-buliding-blocks, auxiliary class Liquid Crystal &OLED Materials, name is 4-Propylphenol, and the molecular formula is C14H31NO2, Recommanded Product: 4-Propylphenol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Kennedy, C. Rose published the artcileSynergistic Ion-Binding Catalysis Demonstrated via an Enantioselective, Catalytic [2,3]-Wittig Rearrangement, Category: alcohols-buliding-blocks, the publication is ACS Central Science (2016), 2(6), 416-423, database is CAplus and MEDLINE.

Sigmatropic rearrangements number among the most powerful complexity-building transformations in organic synthesis but have remained largely insensitive to enantioselective catalysis due to the diffuse nature of their transition structures. Here, we describe a synergistic ion-binding strategy for asym. catalysis of anionic sigmatropic rearrangements. This approach is demonstrated with the enantioselective [2,3]-Wittig rearrangement of α-allyloxy carbonyl compounds to afford highly enantioenriched homoallylic alc. products. Chiral thiourea catalysts are shown to engage reactive anions and their countercations through a cooperative set of attractive, noncovalent interactions. Catalyst structure-reactivity-selectivity relationship studies and computational analyses provide insight into catalyst-substrate interactions responsible for enantioinduction and allude to the potential generality of this catalytic strategy.

ACS Central Science published new progress about 83706-94-9. 83706-94-9 belongs to alcohols-buliding-blocks, auxiliary class Trifluoromethylated Building Blocks, name is (E)-4,4,4-Trifluorobut-2-en-1-ol, and the molecular formula is C4H5F3O, Category: alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Quattrosoldi, Silvia published the artcileBio-based and one-day compostable poly(diethylene 2,5-furanoate) for sustainable flexible food packaging: Effect of ether-oxygen atom insertion on the final properties, Quality Control of 111-29-5, the publication is Chemosphere (2022), 291(Part_2), 132996, database is CAplus and MEDLINE.

In the present work, the effect of ether oxygen atom introduction in a furan ring-containing polymer has been evaluated. Solvent-free polycondensation process permitted the preparation of high mol. weight poly(diethylene 2,5-furandicarboxylate) (PDEF), by reacting the di-Me ester of 2,5-furandicarboxylic acid with diethylene glycol. After mol. and thermal characterization, PDEF mech. response and gas barrier properties to O₂ and CO₂, measured at different temperatures and humidity, were studied and compared with those of poly(butylene 2,5-furandicarboxylate) (PBF) and poly(pentamethylene 2,5-furanoate) (PPeF) previously determined Both PDEF and PPeF films were amorphous, differently from PBF one. As concerns mech. response, PDEF is more flexible than PBF but stiffer than PPeF. Moreover, PDEF is the most thermally stable (temperature of maximum degradation rate being 418 for PDEF, 407 for PBF and 414°C for PPeF) and hydrophilic (water contact angle being 74° for PDEF, 90° for PBF and 93° for PPeF), with gas barrier performances very similar to those of PPeF (O₂ and CO₂ transmission rate being 0.0022 and 0.0018 for PDEF and, 0.0016 and 0.0014 cm³ cm/m² d atm for PPeF). Lab scale composting experiments indicated that PDEF and PPeF were compostable, the former degrading faster, in just one day. The results obtained are explained on the basis of the high electronegativity of ether oxygen atom with respect to the carbon one, and the consequent increase of dipoles along the macromol.

Chemosphere published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C5H12O2, Quality Control of 111-29-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Pattanaik, Sandip published the artcileCobalt-Catalyzed Selective Synthesis of Disiloxanes and Hydrodisiloxanes, Recommanded Product: Triethylsilanol, the publication is ACS Catalysis (2019), 9(6), 5552-5561, database is CAplus.

Selective syntheses of sym. siloxanes and cyclotetrasiloxanes are attained from reactions of silanes and dihydrosilanes, resp., with H₂O, and the reactions are catalyzed by a NNN^HtBu Co(II) pincer complex. When phenylsilane was subjected to catalysis with H₂O, a siloxane cage consisting 12 Si and 18 O centers was obtained and remarkably the reaction proceeded with liberation of 3 equiv of H₂ (36 H₂) under mild exptl. conditions. Upon reaction of silane with different silanols, highly selective and controlled syntheses of higher order monohydrosiloxanes and disiloxymonohydrosilanes were achieved by Co catalysis. The liberated H₂ is the only byproduct observed in all of these transformations. Mechanistic studies indicated that the reactions occur via a homogeneous pathway. Kinetic and independent experiments confirmed the catalytic oxidation of silane to silanol, and further dehydrocoupling processes are involved in syntheses of sym. siloxanes, cyclotetrasiloxanes, and siloxane cage compounds, whereas the unsym. monohydrosiloxane syntheses from silanes and silanols proceeded via dehydrogenative coupling reactions. Overall these Co-catalyzed oxidative coupling reactions are based on the Si-H, Si-OH, and O-H bond activation of silane, silanol, and H₂O, resp. Catalytic cycles consisting of Co(II) intermediates probably are operative.

ACS Catalysis published new progress about 597-52-4. 597-52-4 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is Triethylsilanol, and the molecular formula is C6H16OSi, Recommanded Product: Triethylsilanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Capon, Brian published the artcileSome studies on the tautomerism of heterocyclic and homocyclic compounds, Quality Control of 17236-59-8, the publication is Pure and Applied Chemistry (1987), 59(12), 1577-84, database is CAplus.

The following hydroxy derivatives of heterocyclic compounds have been generated in solution and characterized by ¹H-NMR spectroscopy: 3-hydroxyfuran, 3-hydroxythiophene, 3-hydroxypyrrole, 3-hydroxy-1-methylpyrrole, 3-hydroxybenzofuran, 3-hydroxybenzothiophene, 3-hydroxyindole, 3-hydroxy-1-methylindole, 2-hydroxythiophene, 2-hydroxybenzothiophene, 2,5-dihydroxythiophene. The rate and equilibrium constants for their ketonization have been measured and are discussed. The following hydroxy derivatives of homocyclic compounds were also generated, characterized and investigated: 1-hydroxyindene, 2-hydroxyindene, 1-hydroxycyclohepta-1,3,5-triene, 3-hydroxycyclohepta-1,3,5-triene, hydroxycyclooctatetraene, and 3-hydroxycycloocta-1,3,5-triene. The mechanism of hydrolysis of heterocyclic Me ethers derived from furan, thiophene, 1-methylpyrrole and their benzo-derivatives has been investigated and a change in rate limiting step from C-protonation to nucleophilic attack by water on the intermediate cation detected.

Pure and Applied Chemistry published new progress about 17236-59-8. 17236-59-8 belongs to alcohols-buliding-blocks, auxiliary class Thiophene,Alcohol, name is Thiophen-3-ol, and the molecular formula is C4H4OS, Quality Control of 17236-59-8.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts