Tag: M.W=100-150

Wang, Jie; Yang, Weiyao; Wu, Cai; Gong, Yahui; Zhang, Jian; Shen, Chun published the artcile< Upgrading n-butanol to branched alcohols over Ni/CaxMgyO>, Application In Synthesis of 104-76-7, the main research area is upgrading butanol branched alc nickel calcium magnesium oxygen.

Despite the intensive development of heterogeneous catalysts with transition metal for the Guerbet reaction, a detailed understanding of the metal species and reaction mechanism (rate-determining step and active sites) is still deficient. Herein, we have developed a series of Ni/CaxMgyO catalysts to upgrade n-butanol into branched 2-ethyl-1-hexanol and establish the structure-activity correlation. Given the formation of solid solution between NiO and MgO, the addition of Mg element contributes to the formation of highly dispersed Ni nanoparticles with a small mean size. After optimization in reaction conditions, the highest conversion and selectivity of 80.2 and 79.1%, resp., were achieved at 240°C. The pivotal role of Ni0 sites and base sites during the Guerbet reaction, as confirmed by the selective poison experiments could be attributed to their synergistic catalysis during the dehydrogenation of n-butanol, which is the rate-determining step of the whole process. Moreover, a possible reaction mechanism for this rate-determining step over Ni/CaxMgyO catalysts was proposed based on exptl. results. Overall, this work pushes forward the understanding of the reaction mechanism of the Guerbet reaction over transition-metal-decorated catalysts, which would be constructive for the rational design of heterogeneous catalysts. Efficient upgrading of n-butanol to 2-ethyl-1-hexanol was achieved over Ni/CaxMgyO catalysts, and understanding about the reaction mechanism was pushed forward.

ACS Sustainable Chemistry & Engineering published new progress about Alcohols, branched Role: SPN (Synthetic Preparation), PREP (Preparation). 104-76-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H18O, Application In Synthesis of 104-76-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

De Almeida, Laiza A.; Marcondes, Thayna H.; Milagre, Cintia D. F.; Milagre, Humberto M. S. published the artcile< Lipase-oxovanadium heterogeneous catalysis system: a robust protocol for the dynamic kinetic resolution of sec-alcohols>, Computed Properties of 403-41-8, the main research area is lipase oxovanadium dynamic kinetic resolution secondary alc.

Herein, we present a robust and eco-friendly dynamic kinetic resolution (DKR) protocol for secondary alcs. using a combined heterogeneous catalytic CAL-B/VOSO4 system at 50°C in the relatively green solvent heptane. This catalytic system is active and chemo- and enantioselective for up to 5 cycles. A set of 13 aromatic and heteroaromatic secondary alcs. were evaluated to determine the substrate scope. The performance of the combined CAL-B/VOSO4 system was improved by employing a low-cost, homemade Teflon tube to compartmentalize the catalysts in one-pot conditions, making this system for up to 8 reaction cycles.

ChemCatChem published new progress about Enantioselective biochemical synthesis. 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Computed Properties of 403-41-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Hachula, Barbara; Kaminska, Ewa; Koperwas, Kajetan; Wrzalik, Roman; Jurkiewicz, Karolina; Tarnacka, Magdalena; Scelta, Demetrio; Fanetti, Samuele; Pawlus, Sebastian; Paluch, Marian; Kaminski, Kamil published the artcile< A study of O-H···O hydrogen bonds along various isolines in 2-ethyl-1-hexanol. Temperature or pressure - which parameter controls their behavior?>, Recommanded Product: 2-Ethylhexan-1-ol, the main research area is ethyl hexanol hydrogen bond vibrational frequency IR spectrum; Hydrogen bond; Intramolecular dynamics; Isolines; Pressure; Temperature.

The nature of H-bonding interactions is still far from being understood despite intense exptl. and theor. studies on this subject carried out by the leading research centers. In this paper, by a combination of unique high-pressure IR, dielec. and volumetric data, the intramol. dynamics of hydroxyl moieties (which provides direct information about H-bonds) was studied along various isolines, i.e., isotherms, isobars, isochrones, and isochores, in a simple monohydroxy alc. (2-ethyl-1-hexanol). This allowed us to discover that the temperature controls the intermol. hydrogen bonds, which then affect the intramol. dynamics of O-H units. Although the role of d. fluctuations gets stronger as temperature rises. We also demonstrated a clear connection between the intra- and intermol. dynamics of the associating liquid at high pressure. The data reported herein open a new perspective to explore this important aspect of the glass transition phenomenon and understand H-bonding interactions at varying thermodn. conditions.

Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy published new progress about Glass transition temperature. 104-76-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H18O, Recommanded Product: 2-Ethylhexan-1-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chalupnik, Paulina; Vialko, Alina; Pickering, Darryl S.; Hinkkanen, Markus; Donbosco, Stephanie; Moeller, Thor C.; Jensen, Anders A.; Nielsen, Birgitte; Bay, Yasmin; Kristensen, Anders S.; Johansen, Tommy N.; Latka, Kamil; Bajda, Marek; Szymanska, Ewa published the artcile< Discovery of the First Highly Selective Antagonist of the GluK3 Kainate Receptor Subtype>, COA of Formula: C9H8O, the main research area is quinoxalinedione preparation glutamate receptor antagonist; glutamate receptors; kainate receptors; subunit selectivity.

In search of selective ligands for the GluK3 kainate receptor subtype, a series of I [R = 3-Me Ph, 4-Me Ph, 4-Et Ph, etc] analogs was synthesized and pharmacol. characterized at selected recombinant ionotropic glutamate receptors. Among them, compound I [R = imidazo[1,2-b]pyridazin-3-ylmethyl] was found to be a competitive GluK3 antagonist with submicromolar affinity and unprecedented high binding selectivity, showing a 400-fold preference for GluK3 over other homomeric receptors GluK1, GluK2, GluK5 and GluA2. Furthermore, in functional assays performed for selected metabotropic glutamate receptor subtypes, I [R = imidazo[1,2-b]pyridazin-3-ylmethyl] did not show agonist or antagonist activity. The mol. determinants underlying the observed affinity profile of I [R = imidazo[1,2-b]pyridazin-3-ylmethyl] were analyzed using mol. docking and mol. dynamics simulations performed for individual GluK1 and GluK3 ligand-binding domains.

International Journal of Molecular Sciences published new progress about Kainate receptors Role: BSU (Biological Study, Unclassified), BIOL (Biological Study) (GluK3). 10602-04-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C9H8O, COA of Formula: C9H8O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Jia, Bing; Jiang, Xiaobo; Chen, Xiubin; Dong, Shihua published the artcile< Experimental determination and modeling of liquid-liquid equilibrium for ternary mixtures composed of water, epichlorohydrin and different solvents>, Safety of 2-Ethylhexan-1-ol, the main research area is water epichlorohydrin solvent ternary mixture liquid equilibrium modeling.

Liquid-liquid equilibrium (LLE) data for water + epichlorohydrin + {chloroform or iso-Pr ether or Me tert-Bu ether or iso-Pr acetate or ethylacetate or 2-ethyl-1-hexanol} systems at 308.2 K under 101.3 kPa were determined The distribution coefficient and the separation factor were used to judge the extraction efficiency of different solvents on epichlorohydrin removal from water. The Othmer-Tobias, Hand, and Bachman equations were applied to check the reliability of the exptl. LLE data. Furthermore, the exptl. LLE data were successfully correlated with the NRTL and UNIQUAC models with all the RMSD values were less than 0.57%.

Journal of Molecular Liquids published new progress about Extraction. 104-76-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H18O, Safety of 2-Ethylhexan-1-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Li, Xuan; Jiang, Min; Zhu, Xiaolong; Song, Xiuyan; Deng, Qirong; Lv, Jian; Yang, Daoshan published the artcile< A desulphurization strategy for Sonogashira couplings by visible light/copper catalysis>, Name: (4-Ethynylphenyl)methanol, the main research area is alkyne sulfonium salt desulfurization Sonogashira coupling copper catalyst.

Herein, a new copper-based catalyst, [(binap)(tpy)Cu]Cl I applied in the visible-light promoted Sonogashira coupling reactions has been developed. This mild protocol results in various substituted alkynes RCCH (R = Ph, 2-naphthyl, 2-thienyl, etc.) from simple sulfonium salts II (R1 = Ph, 1-naphthyl, 2H-1,3-benzodioxol-5-yl, etc.) which can be easily prepared from com. available and inexpensive substrates. This study will broaden the still limited strategies of copper photocatalysts in organic transformations.

Organic Chemistry Frontiers published new progress about Alkynes, aryl Role: RCT (Reactant), RACT (Reactant or Reagent). 10602-04-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C9H8O, Name: (4-Ethynylphenyl)methanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Tan, Hui Ru; Lau, Hazel; Liu, Shao Quan; Tan, Lay Peng; Sakumoto, Shunichi; Lassabliere, Benjamin; Leong, Kwong-Chee; Sun, Jingcan; Yu, Bin published the artcile< Characterisation of key odourants in Japanese green tea using gas chromatography-olfactometry and gas chromatography-mass spectrometry>, Quality Control of 104-76-7, the main research area is green tea odorant gas chromatog mass spectrometry olfactometry Japan.

Japanese green tea is becoming increasingly popular worldwide due to its pleasant aroma. The volatiles of four types of Japanese green tea (Sencha, Matcha, Gyokuro, and Hojicha) were extracted sep. by headspace solid-phase microextraction (HS-SPME) and solvent-assisted flavor evaporation (SAFE), and then analyzed using gas chromatog.-mass spectrometry (GC-MS). The aroma-active compounds in each type of green tea were identified by aroma extract dilution anal. (AEDA) of its SAFE extract The odourants exhibiting the highest flavor dilution (FD) factor of 27 in Sencha were indole and methional. For Matcha, nonanal had the highest FD factor of 243. The odourant in Gyokuro with the highest FD factor of 27 was indole. For Hojicha, the odor-active compounds exhibiting high FD factor of 729 and 243 were 2,3-diethylpyrazine and 2,3-diethyl-5-methylpyrazine, resp. Sensory evaluation was then done on the SAFE extract to understand the overall aroma profile of each type of green tea. Based on sensory evaluation results, steamed green teas (Sencha, Matcha, and Gyokuro) had leafier and higher floral notes while roasted green tea (Hojicha) showed higher roasty and woody notes. Finally, principal component anal. (PCA) of data obtained from GC-MS anal. demonstrated marked separation of these four types of Japanese green tea.

LWT–Food Science and Technology published new progress about Flavor. 104-76-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H18O, Quality Control of 104-76-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Liao, Yangzhen; Ran, Yu; Liu, Guijun; Liu, Peijun; Liu, Xiaozu published the artcile< Transition-metal-free radical relay cyclization of vinyl azides with 1,4-dihydropyridines involving a 1,5-hydrogen-atom transfer: access to α-tetralone scaffolds>, COA of Formula: C9H8O, the main research area is tetralone scaffold preparation green chem diastereoselective; vinyl azide dihydropyridine radical hydrogen transfer cyclization.

The remote C(sp3)-H functionalization enabled by a radical-mediated 1,5-hydrogen-atom transfer (HAT) process using 1,4-dihydropyridines I (R = cyclohexyl, 3-phenyl-2-methylpropyl, 1-cyclohexylethyl, etc.; R1 = C(O)OEt, CN) and vinyl azides R2C(=CH2)N3 (R2 = 2-chlorophenyl, 1-naphthyl, benzofuran-2-yl, etc.) as precursors has been described. In this study, 1,4-dihydropyridines I can function as 1,2-diradical synthons through sequential homolytic cleavage of an ipso-C-C bond and a β-C(sp3)-H bond. This reaction offers facile access to a diverse range of α-tetralones e.g., II with excellent stereoselectivity. The utility of the present method is further highlighted by its application to rapid assembly of the tetracyclic scaffold present in furanosteroids as well as the synthesis of aromatic amines.

Organic Chemistry Frontiers published new progress about Alkyl azides Role: RCT (Reactant), RGT (Reagent), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 10602-04-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C9H8O, COA of Formula: C9H8O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Murcia, M. D.; Serrano-Arnaldos, M.; Ortega-Requena, S.; Maximo, F.; Bastida, J.; Montiel, M. C. published the artcile< Optimization of a sustainable biocatalytic process for the synthesis of ethylhexyl fatty acids esters>, Application of C8H18O, the main research area is lipase esterification ethylhexyl fatty acid ester.

Biocatalytic synthesis of ethylhexyl palmitate and ethylhexyl stearate as natural alternatives of cyclomethicone has been studied. In this work the esters have been obtained with two com. enzymes: Novozym435 and Novozym40086 in a “”solvent free”” system. Operational conditions have been optimized using exptl. design and response surface methodol. In the optimum reaction conditions conversion values were higher than 85% in one hour in all the cases. Operation in vacuum reactors with constant N2 bubbling improved the obtained results since it favors water removal and, in consequence, the shifting reaction equilibrium in the way of the synthesis. Besides, Candida antarctica lipase Novozym435 was the most effective, reaching a conversion value of 98% in 45 min. However, cost study revealed that the process is cheaper when using Novozym40086 in open-air reactors.

Catalysis Today published new progress about Biochemical reaction kinetics. 104-76-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H18O, Application of C8H18O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Murugesan, Kathiravan; Alshammari, Ahmad S.; Sohail, Manzar; Beller, Matthias; Jagadeesh, Rajenahally V. published the artcile< Monodisperse nickel-nanoparticles for stereo- and chemoselective hydrogenation of alkynes to alkenes>, SDS of cas: 10602-04-7, the main research area is alkene preparation diastereoselective chemoselective green chem; alkyne hydrogenation monodisperse nickel nanocatalyst.

The use of monosaccharides for the preparation of novel nickel nanoparticles (NP), which constitute selective hydrogenation catalysts has been reported. For example, immobilization of fructose and Ni(OAc)2 on silica and subsequent pyrolysis under inert atm. produced graphitic shells encapsulated Ni-NP with uniform size and distribution. Interestingly, fructose acts as structure controlling compound to generate specific graphitic layers and the formation of monodisperse NP. These nanoparticles enable the hydrogenation of a series of functionalized and structurally diverse aromatic, heterocyclic and aliphatic alkynes R1CCR2 (R1 = 1-hydroxyoct-8-yl, Ph, cyclohexyl, benzothiophen-3-yl, etc.; R2 = H, Et, Ph, 1,3-dioxo-1,3-dihydro-2-benzofuran-5-yl, etc.) to the corresponding alkenes R1CH=CHR2 with excellent stereo- (98-100% Z-alkene formation) and chemoselectivity.

Journal of Catalysis published new progress about Alkenes Role: SPN (Synthetic Preparation), PREP (Preparation). 10602-04-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C9H8O, SDS of cas: 10602-04-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts