Tag: M.W=100-150

Simple alcohols are found widely in nature. Ethanol is the most prominent because it is the product of fermentation, a major energy-producing pathway. 533-73-3, formula is C6H6O3, Other simple alcohols, chiefly fusel alcohols, are formed in only trace amounts. More complex alcohols however are pervasive, as manifested in sugars, some amino acids, and fatty acids. , Application of C6H6O3

Li, Jie;Li, Yi;Wu, Haisuo;Naraginti, Saraschandra;Wu, Yunbo research published 《 Facile synthesis of ZnO nanoparticles by Actinidia deliciosa fruit peel extract: Bactericidal, anticancer and detoxification properties》, the research content is summarized as follows. Synthesis of nanoparticles by eco-friendly method pulled an extensive concern worldwide due its biocompatibility and wide range of applications as catalysts, microbicidal agents, cancer treatment, sensors, etc. Though different chem. methods available for preparation of ZnO nanoparticles, synthesis by utilizing plant material is an excellent substitute and green method as well. The present study describes preparation of ZnO nanoparticles by low-cost green synthetic way using Actinidia deliciosa (kiwi) fruit peel extract and its excellent biol. and catalytic properties. The synthesized nanoparticles were well characterized by UV visible spectroscopy, X-ray diffraction (XRD), Fourier transform IR spectroscopy (FTIR), SEM (SEM), Transmission electron microscopy (TEM) and Energy-dispersive X-ray spectroscopy (EDAX). The bactericidal activity of the ZnO nanoparticles was determined by using Staphylococcus aureus (S. aureus), while mechanism of cell death was studied by SEM images. Superior anticancer activity was also observed in inhibiting the colon cancer cells (HCT116) by the ZnO nanoparticles. In addition, ZnO nanoparticles showed efficient photocatalytic activity towards degradation of p-bromophenol, about 96.3% within 120 min. Furthermore, phytotoxicity of the intermediate products was analyzed using Vigna radiata (V. radiata) as a model plant. About 8.0% of germination index (GI) was observed in pure p-BP while it increased to 82.3%, and exhibited that the detoxification of p-BP was attained after 120 min of degradation Thus, the present study demonstrates ZnO nanoparticles prepared from simple, rapid, inexpensive, eco-friendly and efficient green method gives alternative root for biomedicine and wastewater treatment technologies.

Application of C6H6O3, Benzene-1, 2, 4-triol, also known as hydroxyhydroquinone or 1, 2, 4-benzenetriol, belongs to the class of organic compounds known as hydroxyquinols and derivatives. Hydroxyquinols and derivatives are compounds containing a 1, 2, 4-trihydroxybenzene moiety. Benzene-1, 2, 4-triol is soluble (in water) and a very weakly acidic compound (based on its pKa). Outside of the human body, benzene-1, 2, 4-triol can be found in tea. This makes benzene-1, 2, 4-triol a potential biomarker for the consumption of this food product.
Benzene-1,2,4-triol is a benzenetriol carrying hydroxy groups at positions 1, 2 and 4. It has a role as a mouse metabolite.
1,2,4-Benzenetriol is a metabolite of benzene.
1,2,4-Benzenetriol is an intermediary metabolite of benzene that is present in roasted coffee beans. It is mutagenic and it causes cleaving of DNA single strands by the generation of reactive oxygen species.
1,2,4-Benzenetriol is a reactive molecule that has been shown to have hydrogen bonding interactions with copper chloride. It has been proposed as an inhibitor of methyltransferase, which is involved in the synthesis of methionine. Studies have shown that 1,2,4-Benzenetriol can also inhibit iron homeostasis and transfer reactions. The x-ray diffraction data for this compound shows that it forms a complex with the hydroxyl group. This complex is stabilized by hydrogen bonding interactions with the hydroxylic proton of the 1,2,4-benzenetriol molecule. 1,2,4-Benzenetriol has been shown to be toxic to HL-60 cells and K562 cells at concentrations greater than 5 mM. It has also been found to be effective against chlorogenic acids and other compounds in energy metabolism studies at concentrations between 0.5 and 2 mM., 533-73-3.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Application of C6H6O3, In chemistry, an alcohol is a type of organic compound that carries at least one hydroxyl functional group (−OH) bound to a saturated carbon atom. 533-73-3, name is Benzene-1,2,4-triol, An important class of alcohols, of which methanol and ethanol are the simplest examples, includes all compounds which conform to the general formula CnH2n+1OH.

Li, Tao;Abdelhaleem, Amal;Chu, Wei;Xu, Weicheng research published 《 Efficient activation of oxone by pyrite for the degradation of propanil: Kinetics and degradation pathway》, the research content is summarized as follows. Pyrite (FeS₂) is an abundant sulfide-associated iron mineral that exists in the earth. In this study, the pyrite/oxone process was demonstrated to be an effective approach for the catalytic degradation of propanil, where more than 90% decay ([propanil]₀ = 0.01 mM) was achieved within 15 min. Typically, the effects of various exptl. parameters, including catalyst loading, oxone dosage, propanil concentration, and initial solution pH, were examined Two optimal reaction pH values were observed at pH 9.1 and pH 2.9. The generated SO₄^– and OH were verified to be the dominant reactive radicals and primarily responsible for the propanil degradation Both Fe(II) regeneration and sulfur conversion play an important role in oxone activation mechanism and effectively aid the catalytic activity of pyrite. Different co-existing natural water constituents exert dissimilar effects on the pyrite/oxone process. Addnl., the reusability test of pyrite exhibited a reasonable catalytic activity. The pyrite/oxone process was proven efficient in terms of propanil mineralization. A series of reaction intermediates was detected via four major degradation pathways. Overall, the pyrite/oxone process could be a promising approach for the removal of organic compounds in water.

Application of C6H6O3, Benzene-1, 2, 4-triol, also known as hydroxyhydroquinone or 1, 2, 4-benzenetriol, belongs to the class of organic compounds known as hydroxyquinols and derivatives. Hydroxyquinols and derivatives are compounds containing a 1, 2, 4-trihydroxybenzene moiety. Benzene-1, 2, 4-triol is soluble (in water) and a very weakly acidic compound (based on its pKa). Outside of the human body, benzene-1, 2, 4-triol can be found in tea. This makes benzene-1, 2, 4-triol a potential biomarker for the consumption of this food product.
Benzene-1,2,4-triol is a benzenetriol carrying hydroxy groups at positions 1, 2 and 4. It has a role as a mouse metabolite.
1,2,4-Benzenetriol is a metabolite of benzene.
1,2,4-Benzenetriol is an intermediary metabolite of benzene that is present in roasted coffee beans. It is mutagenic and it causes cleaving of DNA single strands by the generation of reactive oxygen species.
1,2,4-Benzenetriol is a reactive molecule that has been shown to have hydrogen bonding interactions with copper chloride. It has been proposed as an inhibitor of methyltransferase, which is involved in the synthesis of methionine. Studies have shown that 1,2,4-Benzenetriol can also inhibit iron homeostasis and transfer reactions. The x-ray diffraction data for this compound shows that it forms a complex with the hydroxyl group. This complex is stabilized by hydrogen bonding interactions with the hydroxylic proton of the 1,2,4-benzenetriol molecule. 1,2,4-Benzenetriol has been shown to be toxic to HL-60 cells and K562 cells at concentrations greater than 5 mM. It has also been found to be effective against chlorogenic acids and other compounds in energy metabolism studies at concentrations between 0.5 and 2 mM., 533-73-3.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In general, the hydroxyl group makes alcohols polar. Those groups can form hydrogen bonds to one another and to most other compounds. 533-73-3, formula is C6H6O3, Owing to the presence of the polar OH alcohols are more water-soluble than simple hydrocarbons. Methanol, ethanol, and propanol are miscible in water. Butanol, with a four-carbon chain, is moderately soluble. Name: Benzene-1,2,4-triol

Li, Yan;Fan, Wenjie;Gong, Qineng;Tian, Jie;Zhou, Mi;Li, Qing;Uwituze, Laura B.;Zhang, Zhichao;Hong, Ran;Wang, Renxiao research published 《 Structure-Based Optimization of 3-Phenyl-N-(2-(3-phenylureido)ethyl)thiophene-2-sulfonamide Derivatives as Selective Mcl-1 Inhibitors》, the research content is summarized as follows. Selective Mcl-1 inhibitors may overcome the drug resistance caused by current anti-apoptotic Bcl-2 protein inhibitors in tumors with Mcl-1 overexpression. Based on previously discovered compounds with a 3-phenylthiophene-2-sulfonamide core moiety, in this work, we have obtained new compounds with improved binding affinity and/or selectivity under the guidance of structure-based design. The most potent compounds achieved sub-micromolar binding affinities to Mcl-1 (K_i ~0.4μM) and good cytotoxicity (IC₅₀ < 10μM) on several tumor cells. ¹⁵N-heteronuclear single-quantum coherence NMR spectra suggested that these compounds bound to the BH3-binding groove on Mcl-1. Several cellular assays revealed that FWJ-D4 as well as its precursor FWJ-D5 effectively induced caspase-dependent apoptosis, and their target engagement at Mcl-1 was confirmed by co-immunoprecipitation experiments Treatment with FWJ-D5 at 50 mg/kg every 2 days on an RS4;11 xenograft mouse model for 22 days led to 75% reduction in tumor volume without body weight loss.

533-73-3, Benzene-1, 2, 4-triol, also known as hydroxyhydroquinone or 1, 2, 4-benzenetriol, belongs to the class of organic compounds known as hydroxyquinols and derivatives. Hydroxyquinols and derivatives are compounds containing a 1, 2, 4-trihydroxybenzene moiety. Benzene-1, 2, 4-triol is soluble (in water) and a very weakly acidic compound (based on its pKa). Outside of the human body, benzene-1, 2, 4-triol can be found in tea. This makes benzene-1, 2, 4-triol a potential biomarker for the consumption of this food product.
Benzene-1,2,4-triol is a benzenetriol carrying hydroxy groups at positions 1, 2 and 4. It has a role as a mouse metabolite.
1,2,4-Benzenetriol is a metabolite of benzene.
1,2,4-Benzenetriol is an intermediary metabolite of benzene that is present in roasted coffee beans. It is mutagenic and it causes cleaving of DNA single strands by the generation of reactive oxygen species.
1,2,4-Benzenetriol is a reactive molecule that has been shown to have hydrogen bonding interactions with copper chloride. It has been proposed as an inhibitor of methyltransferase, which is involved in the synthesis of methionine. Studies have shown that 1,2,4-Benzenetriol can also inhibit iron homeostasis and transfer reactions. The x-ray diffraction data for this compound shows that it forms a complex with the hydroxyl group. This complex is stabilized by hydrogen bonding interactions with the hydroxylic proton of the 1,2,4-benzenetriol molecule. 1,2,4-Benzenetriol has been shown to be toxic to HL-60 cells and K562 cells at concentrations greater than 5 mM. It has also been found to be effective against chlorogenic acids and other compounds in energy metabolism studies at concentrations between 0.5 and 2 mM., Name: Benzene-1,2,4-triol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Simple alcohols are found widely in nature. Ethanol is the most prominent because it is the product of fermentation, a major energy-producing pathway. 533-73-3, formula is C6H6O3, Other simple alcohols, chiefly fusel alcohols, are formed in only trace amounts. More complex alcohols however are pervasive, as manifested in sugars, some amino acids, and fatty acids. , Quality Control of 533-73-3

Lee, Yeshin;Jung, Hye-In;Jang, Yeon-Im;An, Byeong-Kwan research published 《 Ecofriendly Multifunctional Monodisperse Spherical Polymer Colloids from Hyperbranched Poly(p-phenyl ester) Phenol》, the research content is summarized as follows. Multifunctional, monodisperse, and hyperbranched poly(p-Ph ester) phenol (HPPEP) colloids are prepared using com. available inexpensive monomers (i.e., terephthaloyl chloride (A₂) and phloroglucinol (B₃)) via a simple condensation polymerization reaction (A₂ + B₃) at room temperature Because of their sym., rigid, highly branched, and cross-linked structure and the presence of the terminal phenolic units, the formation of highly monodisperse HPPEP colloids (coefficient of variation < 1.6%) can be realized under trimethylamine base conditions without any emulsifier (or surfactants) and expensive catalyst. Owing to their rigid aromatic and cross-linked structure, the HPPEP colloids exhibit excellent thermal, chem., and mech. resistances. Furthermore, the phenolic surface groups of HPPEP colloids enable the generation of highly neg. surface charges (-60 mV) and catalytic protons (0.26 mmol H⁺/g) while enhancing surface functionality by chem. binding to red, green, and blue fluorescent dye mols. Through carbonization, HPPEP colloids can be directly transformed into monodisperse porous carbon spheres with a large surface area (a_s,BET = 644.99 m² g^-1). Moreover, the HPPEP colloids can fully decompose into environmentally benign monomers after being exposed to an alkali environment.

Quality Control of 533-73-3, Benzene-1, 2, 4-triol, also known as hydroxyhydroquinone or 1, 2, 4-benzenetriol, belongs to the class of organic compounds known as hydroxyquinols and derivatives. Hydroxyquinols and derivatives are compounds containing a 1, 2, 4-trihydroxybenzene moiety. Benzene-1, 2, 4-triol is soluble (in water) and a very weakly acidic compound (based on its pKa). Outside of the human body, benzene-1, 2, 4-triol can be found in tea. This makes benzene-1, 2, 4-triol a potential biomarker for the consumption of this food product.
Benzene-1,2,4-triol is a benzenetriol carrying hydroxy groups at positions 1, 2 and 4. It has a role as a mouse metabolite.
1,2,4-Benzenetriol is a metabolite of benzene.
1,2,4-Benzenetriol is an intermediary metabolite of benzene that is present in roasted coffee beans. It is mutagenic and it causes cleaving of DNA single strands by the generation of reactive oxygen species.
1,2,4-Benzenetriol is a reactive molecule that has been shown to have hydrogen bonding interactions with copper chloride. It has been proposed as an inhibitor of methyltransferase, which is involved in the synthesis of methionine. Studies have shown that 1,2,4-Benzenetriol can also inhibit iron homeostasis and transfer reactions. The x-ray diffraction data for this compound shows that it forms a complex with the hydroxyl group. This complex is stabilized by hydrogen bonding interactions with the hydroxylic proton of the 1,2,4-benzenetriol molecule. 1,2,4-Benzenetriol has been shown to be toxic to HL-60 cells and K562 cells at concentrations greater than 5 mM. It has also been found to be effective against chlorogenic acids and other compounds in energy metabolism studies at concentrations between 0.5 and 2 mM., 533-73-3.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In general, the hydroxyl group makes alcohols polar. Those groups can form hydrogen bonds to one another and to most other compounds. 533-73-3, formula is C6H6O3, Owing to the presence of the polar OH alcohols are more water-soluble than simple hydrocarbons. Methanol, ethanol, and propanol are miscible in water. Butanol, with a four-carbon chain, is moderately soluble. Product Details of C6H6O3

Kim, Yelim;Lee, Hongshin;Oh, Hoon;Haider, Zeeshan;Choi, Jaemin;Shin, Yong-Uk;Kim, Hyoung-il;Lee, Jaesang research published 《 Revisiting the Oxidizing Capacity of the Periodate-H₂O₂ Mixture: Identification of the Primary Oxidants and Their Formation Mechanisms》, the research content is summarized as follows. This study reexamined the mechanisms for oxidative organic degradation by the binary mixture of periodate and H₂O₂ (PI/H₂O₂) that was recently identified as a new advanced oxidation process. Our findings conflicted with the previous claims that (i) hydroxyl radical (^•OH) and singlet oxygen (¹O₂) contributed as the primary oxidants, and (ii) ^•OH production resulted from H₂O₂ reduction by superoxide radical anion (O₂^•-). PI/H₂O₂ exhibited substantial oxidizing capacity at pH < 5, decomposing organics predominantly by ^•OH. The likelihood of a switch in the major oxidant under varying pH conditions was revealed. IO₄^– as the major PI form under acidic conditions underwent one-electron reduction by H₂O₂ to yield radical intermediates, whereas H₂I₂O₁₀^4- preferentially occurring at pH > 7 caused ¹O₂ generation through two-electron oxidation of H₂O₂. PI reduction by O₂^•- was suggested to be a key reaction in ^•OH production, on the basis of the ESR detection of Me radicals in the DMSO solutions containing PI and KO₂, and the absence of deuterated and ¹⁸O-labeled hydroxylated intermediates during PI activation using D₂O and H₂¹⁸O₂. Finally, simple oxyanion mixing subsequent to electrochem. PI and H₂O₂ production achieved organic oxidation, enabling a potential strategy to minimize the use of chems.

533-73-3, Benzene-1, 2, 4-triol, also known as hydroxyhydroquinone or 1, 2, 4-benzenetriol, belongs to the class of organic compounds known as hydroxyquinols and derivatives. Hydroxyquinols and derivatives are compounds containing a 1, 2, 4-trihydroxybenzene moiety. Benzene-1, 2, 4-triol is soluble (in water) and a very weakly acidic compound (based on its pKa). Outside of the human body, benzene-1, 2, 4-triol can be found in tea. This makes benzene-1, 2, 4-triol a potential biomarker for the consumption of this food product.
Benzene-1,2,4-triol is a benzenetriol carrying hydroxy groups at positions 1, 2 and 4. It has a role as a mouse metabolite.
1,2,4-Benzenetriol is a metabolite of benzene.
1,2,4-Benzenetriol is an intermediary metabolite of benzene that is present in roasted coffee beans. It is mutagenic and it causes cleaving of DNA single strands by the generation of reactive oxygen species.
1,2,4-Benzenetriol is a reactive molecule that has been shown to have hydrogen bonding interactions with copper chloride. It has been proposed as an inhibitor of methyltransferase, which is involved in the synthesis of methionine. Studies have shown that 1,2,4-Benzenetriol can also inhibit iron homeostasis and transfer reactions. The x-ray diffraction data for this compound shows that it forms a complex with the hydroxyl group. This complex is stabilized by hydrogen bonding interactions with the hydroxylic proton of the 1,2,4-benzenetriol molecule. 1,2,4-Benzenetriol has been shown to be toxic to HL-60 cells and K562 cells at concentrations greater than 5 mM. It has also been found to be effective against chlorogenic acids and other compounds in energy metabolism studies at concentrations between 0.5 and 2 mM., Product Details of C6H6O3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Some low molecular weight alcohols of industrial importance are produced by the addition of water to alkenes. 533-73-3, formula is C6H6O3, Ethanol, isopropanol, 2-butanol, and tert-butanol are produced by this general method. Two implementations are employed, the direct and indirect methods. Category: alcohols-buliding-blocks

Kohatsu, Haruki;Kamo, Shogo;Hosokai, Takuya;Kamisuki, Shinji;Machida, Yutaro;Kobayashi, Ryota;Kawasaki, Tsuneomi;Ohgane, Kenji;Kuramochi, Kouji research published 《 Synthesis, photochemical properties, and cytotoxicity of 10-alkylphenazin-2(10H)-ones》, the research content is summarized as follows. The synthesis of a variety of 10-alkylphenazin-2(10H)-ones I [R = Me, benzyl, decyl, etc.] by oxidative coupling between N-alkylbenzene-1,2-diamine and 1,2,4-benzenetriol under an oxygen atm. were realized, and their photochem. and biol. properties were investigated. 10-Methylphenazin-2(10H)-one, a reddish orange pigment, exhibited fluorescence in the visible light region upon exposure to UV light. Interestingly, the fluorescence from I [R = Me] consisted of two components. In addition, the cytotoxic evaluation of various synthetic compounds was performed. Among the compounds tested in this study, I [R = Me] exhibited the most selective cytotoxic activity against human cancer A549 cells compared to normal MRC-5 cells.

533-73-3, Benzene-1, 2, 4-triol, also known as hydroxyhydroquinone or 1, 2, 4-benzenetriol, belongs to the class of organic compounds known as hydroxyquinols and derivatives. Hydroxyquinols and derivatives are compounds containing a 1, 2, 4-trihydroxybenzene moiety. Benzene-1, 2, 4-triol is soluble (in water) and a very weakly acidic compound (based on its pKa). Outside of the human body, benzene-1, 2, 4-triol can be found in tea. This makes benzene-1, 2, 4-triol a potential biomarker for the consumption of this food product.
Benzene-1,2,4-triol is a benzenetriol carrying hydroxy groups at positions 1, 2 and 4. It has a role as a mouse metabolite.
1,2,4-Benzenetriol is a metabolite of benzene.
1,2,4-Benzenetriol is an intermediary metabolite of benzene that is present in roasted coffee beans. It is mutagenic and it causes cleaving of DNA single strands by the generation of reactive oxygen species.
1,2,4-Benzenetriol is a reactive molecule that has been shown to have hydrogen bonding interactions with copper chloride. It has been proposed as an inhibitor of methyltransferase, which is involved in the synthesis of methionine. Studies have shown that 1,2,4-Benzenetriol can also inhibit iron homeostasis and transfer reactions. The x-ray diffraction data for this compound shows that it forms a complex with the hydroxyl group. This complex is stabilized by hydrogen bonding interactions with the hydroxylic proton of the 1,2,4-benzenetriol molecule. 1,2,4-Benzenetriol has been shown to be toxic to HL-60 cells and K562 cells at concentrations greater than 5 mM. It has also been found to be effective against chlorogenic acids and other compounds in energy metabolism studies at concentrations between 0.5 and 2 mM., Category: alcohols-buliding-blocks

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Simple alcohols are found widely in nature. Ethanol is the most prominent because it is the product of fermentation, a major energy-producing pathway. 533-73-3, formula is C6H6O3, Other simple alcohols, chiefly fusel alcohols, are formed in only trace amounts. More complex alcohols however are pervasive, as manifested in sugars, some amino acids, and fatty acids. , Name: Benzene-1,2,4-triol

Kont, Riin;Pihlajaniemi, Ville;Niemela, Klaus;Kuusk, Silja;Marjamaa, Kaisa;Valjamae, Priit research published 《 H₂O₂ in Liquid Fractions of Hydrothermally Pretreated Biomasses: Implications of Lytic Polysaccharide Monooxygenases》, the research content is summarized as follows. Lytic polysaccharide monooxygenases (LPMOs) are important players in enzyme-aided valorization of lignocellulose. However, the recently discovered dependency of LPMO catalysis on H₂O₂ along with H₂O₂-caused inactivation of the enzyme calls for an in-depth understanding of the levels and the dynamics of H₂O₂ in various streams of the processing of lignocellulosic biomass. Using an LPMO-based sensitive detection, we assessed the dynamics of H₂O₂ in the liquid fractions (LFs) of hydrothermally pretreated wheat straw (agricultural residue), birch (hardwood), and pine (softwood). Upon contact with air, H₂O₂ was formed in the LFs of all biomasses. The initially high rate of H₂O₂ formation decayed with the half-life around 1-2 h to a low but stable plateau value. The rates of H₂O₂ formation were much higher than the rates of its accumulation, suggesting that H₂O₂ is an intermediate in aerobic oxidation of the compounds in LFs. Although the general traits were similar, LFs of different biomasses had different rates of H₂O₂ formation and accumulation. LFs of different biomasses also differed by their effect on the enzymic degradation of cellulose. Compositional analyses revealed a number of different compounds that were formed and disappeared upon aerobic oxidation of LFs.

Name: Benzene-1,2,4-triol, Benzene-1, 2, 4-triol, also known as hydroxyhydroquinone or 1, 2, 4-benzenetriol, belongs to the class of organic compounds known as hydroxyquinols and derivatives. Hydroxyquinols and derivatives are compounds containing a 1, 2, 4-trihydroxybenzene moiety. Benzene-1, 2, 4-triol is soluble (in water) and a very weakly acidic compound (based on its pKa). Outside of the human body, benzene-1, 2, 4-triol can be found in tea. This makes benzene-1, 2, 4-triol a potential biomarker for the consumption of this food product.
Benzene-1,2,4-triol is a benzenetriol carrying hydroxy groups at positions 1, 2 and 4. It has a role as a mouse metabolite.
1,2,4-Benzenetriol is a metabolite of benzene.
1,2,4-Benzenetriol is an intermediary metabolite of benzene that is present in roasted coffee beans. It is mutagenic and it causes cleaving of DNA single strands by the generation of reactive oxygen species.
1,2,4-Benzenetriol is a reactive molecule that has been shown to have hydrogen bonding interactions with copper chloride. It has been proposed as an inhibitor of methyltransferase, which is involved in the synthesis of methionine. Studies have shown that 1,2,4-Benzenetriol can also inhibit iron homeostasis and transfer reactions. The x-ray diffraction data for this compound shows that it forms a complex with the hydroxyl group. This complex is stabilized by hydrogen bonding interactions with the hydroxylic proton of the 1,2,4-benzenetriol molecule. 1,2,4-Benzenetriol has been shown to be toxic to HL-60 cells and K562 cells at concentrations greater than 5 mM. It has also been found to be effective against chlorogenic acids and other compounds in energy metabolism studies at concentrations between 0.5 and 2 mM., 533-73-3.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Some low molecular weight alcohols of industrial importance are produced by the addition of water to alkenes. 533-73-3, formula is C6H6O3, Ethanol, isopropanol, 2-butanol, and tert-butanol are produced by this general method. Two implementations are employed, the direct and indirect methods. Recommanded Product: Benzene-1,2,4-triol

Kumar, Sonu;Kaushik, R. D.;Purohit, L. P. research published 《 Novel ZnO tetrapod-reduced graphene oxide nanocomposites for enhanced photocatalytic degradation of phenolic compounds and MB dye》, the research content is summarized as follows. In the present work, a bunch of ZnO tetrapod-reduced graphene oxide (ZTPG) nanocomposites (NCs) were synthesized via a simple and economical in-situ approach using high temperature refluxing method. The phase purity, morphol., optical and photocatalytic properties of NCs were studied comprehensively. Various weight percentage of rGO were proposed for efficient separation of electron hole pairs and improved photodegradation of phenolic compounds and methylene blue (MB) dye. The photocatalytic degradation of 4-chlorophenol (4-CP) and MB dye in aqueous system was performed for the assessment of photodegradation productivity of various ZTPG NCs with illumination of UV-light. The utmost mineralization after photodegradation attained about 94.8% for 4-CP over ZTPG-5 with UV-light exposure for 180 min. Similarly, the efficiency was also found 98.05% for MB dye photodegradation after 90 min UV-light introduction. The improved photocatalytic performance of ZTPG-5 NCs attributed to the enhanced adsorption capacity of 4-CP and MB dye over nanocomposite photocatalyst, effectual suppression of the recombination rate of electron hole pairs by synergistic influence among ZnO tetrapod and rGO sheet.

533-73-3, Benzene-1, 2, 4-triol, also known as hydroxyhydroquinone or 1, 2, 4-benzenetriol, belongs to the class of organic compounds known as hydroxyquinols and derivatives. Hydroxyquinols and derivatives are compounds containing a 1, 2, 4-trihydroxybenzene moiety. Benzene-1, 2, 4-triol is soluble (in water) and a very weakly acidic compound (based on its pKa). Outside of the human body, benzene-1, 2, 4-triol can be found in tea. This makes benzene-1, 2, 4-triol a potential biomarker for the consumption of this food product.
Benzene-1,2,4-triol is a benzenetriol carrying hydroxy groups at positions 1, 2 and 4. It has a role as a mouse metabolite.
1,2,4-Benzenetriol is a metabolite of benzene.
1,2,4-Benzenetriol is an intermediary metabolite of benzene that is present in roasted coffee beans. It is mutagenic and it causes cleaving of DNA single strands by the generation of reactive oxygen species.
1,2,4-Benzenetriol is a reactive molecule that has been shown to have hydrogen bonding interactions with copper chloride. It has been proposed as an inhibitor of methyltransferase, which is involved in the synthesis of methionine. Studies have shown that 1,2,4-Benzenetriol can also inhibit iron homeostasis and transfer reactions. The x-ray diffraction data for this compound shows that it forms a complex with the hydroxyl group. This complex is stabilized by hydrogen bonding interactions with the hydroxylic proton of the 1,2,4-benzenetriol molecule. 1,2,4-Benzenetriol has been shown to be toxic to HL-60 cells and K562 cells at concentrations greater than 5 mM. It has also been found to be effective against chlorogenic acids and other compounds in energy metabolism studies at concentrations between 0.5 and 2 mM., Recommanded Product: Benzene-1,2,4-triol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Simple alcohols are found widely in nature. Ethanol is the most prominent because it is the product of fermentation, a major energy-producing pathway. 533-73-3, formula is C6H6O3, Other simple alcohols, chiefly fusel alcohols, are formed in only trace amounts. More complex alcohols however are pervasive, as manifested in sugars, some amino acids, and fatty acids. , Computed Properties of 533-73-3

Kundu, Kankana;Melsbach, Aileen;Heckel, Benjamin;Schneidemann, Sarah;Kanapathi, Dheeraj;Marozava, Sviatlana;Merl-Pham, Juliane;Elsner, Martin research published 《 Linking Increased Isotope Fractionation at Low Concentrations to Enzyme Activity Regulation: 4-Cl Phenol Degradation by Arthrobacter chlorophenolicus A6》, the research content is summarized as follows. Slow microbial degradation of organic trace chems. (“micropollutants”) has been attributed to either downregulation of enzymic turnover or rate-limiting substrate supply at low concentrations In previous biodegradation studies, a drastic decrease in isotope fractionation of atrazine revealed a transition from rate-limiting enzyme turnover to membrane permeation as a bottleneck when concentrations fell below the Monod constant of microbial growth. With degradation of the pollutant 4-chlorophenol (4-CP) by Arthrobacter chlorophenolicus A6, this study targeted a bacterium which adapts its enzyme activity to concentrations Unlike with atrazine degradation, isotope fractionation of 4-CP increased at lower concentrations, from ε(C) = -1.0 ± 0.5‰ in chemostats (D = 0.090 h^-1, 88 mg L^-1) and ε(C) = -2.1 ± 0.5‰ in batch (c₀ = 220 mg L^-1) to ε(C) = -4.1 ± 0.2‰ in chemostats at 90μg L^-1. Surprisingly, fatty acid composition indicated increased cell wall permeability at high concentrations, while proteomics revealed that catabolic enzymes (CphCI and CphCII) were differentially expressed at D = 0.090 h^-1. These observations support regulation on the enzyme activity level-through either a metabolic shift between catabolic pathways or decreased enzymic turnover at low concentrations-and, hence, reveal an alternative end-member scenario for bacterial adaptation at low concentrations Including more degrader strains into this multidisciplinary anal. approach offers the perspective to build a knowledge base on bottlenecks of bioremediation at low concentrations that considers bacterial adaptation.

533-73-3, Benzene-1, 2, 4-triol, also known as hydroxyhydroquinone or 1, 2, 4-benzenetriol, belongs to the class of organic compounds known as hydroxyquinols and derivatives. Hydroxyquinols and derivatives are compounds containing a 1, 2, 4-trihydroxybenzene moiety. Benzene-1, 2, 4-triol is soluble (in water) and a very weakly acidic compound (based on its pKa). Outside of the human body, benzene-1, 2, 4-triol can be found in tea. This makes benzene-1, 2, 4-triol a potential biomarker for the consumption of this food product.
Benzene-1,2,4-triol is a benzenetriol carrying hydroxy groups at positions 1, 2 and 4. It has a role as a mouse metabolite.
1,2,4-Benzenetriol is a metabolite of benzene.
1,2,4-Benzenetriol is an intermediary metabolite of benzene that is present in roasted coffee beans. It is mutagenic and it causes cleaving of DNA single strands by the generation of reactive oxygen species.
1,2,4-Benzenetriol is a reactive molecule that has been shown to have hydrogen bonding interactions with copper chloride. It has been proposed as an inhibitor of methyltransferase, which is involved in the synthesis of methionine. Studies have shown that 1,2,4-Benzenetriol can also inhibit iron homeostasis and transfer reactions. The x-ray diffraction data for this compound shows that it forms a complex with the hydroxyl group. This complex is stabilized by hydrogen bonding interactions with the hydroxylic proton of the 1,2,4-benzenetriol molecule. 1,2,4-Benzenetriol has been shown to be toxic to HL-60 cells and K562 cells at concentrations greater than 5 mM. It has also been found to be effective against chlorogenic acids and other compounds in energy metabolism studies at concentrations between 0.5 and 2 mM., Computed Properties of 533-73-3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

With respect to acute toxicity, simple alcohols have low acute toxicities. Doses of several milliliters are tolerated. 533-73-3, formula is C6H6O3, For pentanols, hexanols, octanols and longer alcohols, LD50 range from 2–5 g/kg (rats, oral). Ethanol is less acutely toxic.All alcohols are mild skin irritants. Product Details of C6H6O3

Kato, Hiroyuki;Furusawa, Terumi T.;Mori, Reini;Suzuki, Hiromitsu;Kato, Masashi;Shimizu, Motoyuki research published 《 Characterization of two 1,2,4-trihydroxybenzene 1,2-dioxygenases from Phanerochaete chrysosporium》, the research content is summarized as follows. Abstract: Lignin is the most abundant aromatic compound in nature, and it plays an important role in the carbon cycle. White-rot fungi are microbes that are capable of efficiently degrading lignin. Enzymes from these fungi possess exceptional oxidative potential and have gained increasing importance for improving bioprocesses, such as the degradation of organic pollutants. The aim of this study was to identify the enzymes involved in the ring cleavage of the lignin-derived aromatic 1,2,4-trihydroxybenzene (THB) in Phanerochaete chrysosporium, a lignin-degrading basidiomycete. Two intradiol dioxygenases (IDDs), PcIDD1 and PcIDD2, were identified and produced as recombinant proteins in Escherichia coli. In the presence of O₂, PcIDD1 and PcIDD2 acted on eight and two THB derivatives, resp., as substrates. PcIDD1 and PcIDD2 catalyze the ring cleavage of lignin-derived fragments, such as 6-methoxy-1,2,4-trihydroxybenzene (6-MeOTHB) and 3-methoxy-1,2-catechol. The current study also revealed that syringic acid (SA) was converted to 5-hydroxyvanillic acid, 2,6-dimethoxyhydroquinone, and 6-MeOTHB by fungal cells, suggesting that PcIDD1 and PcIDD2 may be involved in aromatic ring fission of 6-MeOTHB for SA degradation This is the first study to show 6-MeOTHB dioxygenase activity of an IDD superfamily member. These findings highlight the unique and broad substrate spectra of PcIDDs, rendering it an attractive candidate for biotechnol. application. Key points: • Novel intradiol dioxygenases (IDD) in lignin degradation were characterized. • PcIDDs acted on lignin-derived fragments and catechol derivatives • Dioxygenase activity on 6-MeOTHB was identified in IDD superfamily enzymes.

Product Details of C6H6O3, Benzene-1, 2, 4-triol, also known as hydroxyhydroquinone or 1, 2, 4-benzenetriol, belongs to the class of organic compounds known as hydroxyquinols and derivatives. Hydroxyquinols and derivatives are compounds containing a 1, 2, 4-trihydroxybenzene moiety. Benzene-1, 2, 4-triol is soluble (in water) and a very weakly acidic compound (based on its pKa). Outside of the human body, benzene-1, 2, 4-triol can be found in tea. This makes benzene-1, 2, 4-triol a potential biomarker for the consumption of this food product.
Benzene-1,2,4-triol is a benzenetriol carrying hydroxy groups at positions 1, 2 and 4. It has a role as a mouse metabolite.
1,2,4-Benzenetriol is a metabolite of benzene.
1,2,4-Benzenetriol is an intermediary metabolite of benzene that is present in roasted coffee beans. It is mutagenic and it causes cleaving of DNA single strands by the generation of reactive oxygen species.
1,2,4-Benzenetriol is a reactive molecule that has been shown to have hydrogen bonding interactions with copper chloride. It has been proposed as an inhibitor of methyltransferase, which is involved in the synthesis of methionine. Studies have shown that 1,2,4-Benzenetriol can also inhibit iron homeostasis and transfer reactions. The x-ray diffraction data for this compound shows that it forms a complex with the hydroxyl group. This complex is stabilized by hydrogen bonding interactions with the hydroxylic proton of the 1,2,4-benzenetriol molecule. 1,2,4-Benzenetriol has been shown to be toxic to HL-60 cells and K562 cells at concentrations greater than 5 mM. It has also been found to be effective against chlorogenic acids and other compounds in energy metabolism studies at concentrations between 0.5 and 2 mM., 533-73-3.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts