Tag: M.W=100-150

Fellechner, Oliver published the artcileLong-Chain Alcohol-Modified Micellar Systems and Their Application in a Continuous Extraction Process, Quality Control of 111-87-5, the main research area is long chain alc micellar extraction micelle surfactant purification.

The integration of an in situ extraction into biocatalytic processes is often limited by the toxicity of organic solvents. Therefore, it is desirable to use water-based extraction systems (for example, aqueous micellar two-phase systems). They can be used, for instance, for the extraction of valuable products from microalgae cultures. Recently, the nonionic surfactant ROKAnol NL5 was identified as a suitable surfactant for this purpose, since it forms an upper micellar phase, enabling an easy separation of whole-cell biocatalysts. However, its application at temperatures below 45 °C is limited by unstable phase boundaries, whereas the maximal temperature to ensure the vitality of the most microalgae cultures is ∼40 °C. To overcome this problem, the addition of long-chain alcs. to the surfactant-water mixture during extraction is suggested in this work. Using 1-hexanol, a continuous extraction process with the model solute trans-cinnamic acid at 40 °C in a stirred column could be realized. The results of a new suggested water/ROKAnol NL5/1-hexanol system at 40 °C (extraction yield, Ycont = 97.67% ± 0.14%; enrichment factor, log10TCA = 2.42 ± 0.03; number of theor. stages, Ntheo = 4.45 ± 0.16) are comparable to those of the water/ROKAnol NL5 system at 45 °C (Ycont = 99.26% ± 0.24%, log10TCA = 2.60 ± 0.10, Ntheo = 5.88 ± 0.67), ensuring, however, no damage of microalgae.

Industrial & Engineering Chemistry Research published new progress about Micellar extraction. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Quality Control of 111-87-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Faltracco, Matteo published the artcileDiastereoselective Synthesis of β-Lactams by Ligand-Controlled Stereodivergent Intramolecular Tsuji-Trost Allylation, Computed Properties of 22483-09-6, the main research area is diastereoselective intramol Tsuji Trost allylation ligand controlled stereodivergent; beta lactam stereoselective preparation.

The diastereoselective synthesis of highly substituted β-lactams by intramol. Tsuji-Trost allylation is reported. Judicious selection of the ligand on palladium allows selective access to either the trans isomer (in generally good to excellent yield with very high diastereomeric excess) or cis isomer (with yields and diastereoselectivity ranging from modest to excellent depending on the substrate). The reaction proceeds under exceedingly mild conditions (rt, no additives) with a broad range of substrates, which are readily accessible by the Ugi reaction.

Journal of Organic Chemistry published new progress about Diastereoselective synthesis. 22483-09-6 belongs to class alcohols-buliding-blocks, name is 2,2-Dimethoxyethanamine, and the molecular formula is C4H11NO2, Computed Properties of 22483-09-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Li, Yiming published the artcileSelective Late-Stage Oxygenation of Sulfides with Ground-State Oxygen by Uranyl Photocatalysis, COA of Formula: C4H10OS, the main research area is photooxidation catalyst uranyl sulfide sulfoxide sulfone; oxygen; oxygenation; photocatalysis; sulfides; uranyl catalysis.

Oxygenation is a fundamental transformation in synthesis. Herein, we describe the selective late-stage oxygenation of sulfur-containing complex mols. with ground-state oxygen under ambient conditions. The high oxidation potential of the active uranyl cation (UO22+) enabled the efficient synthesis of sulfones. The ligand-to-metal charge transfer process (LMCT) from O 2p to U 5f within the O::U::O group, which generates a UV center and an oxygen radical, is assumed to be affected by the solvent and additives, and can be tuned to promote selective sulfoxidation This tunable strategy enabled the batch synthesis of 32 pharmaceuticals and analogs by late-stage oxygenation in an atom- and step-efficient manner.

Angewandte Chemie, International Edition published new progress about Cell proliferation. 505-10-2 belongs to class alcohols-buliding-blocks, name is 3-(Methylthio)propan-1-ol, and the molecular formula is C4H10OS, COA of Formula: C4H10OS.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ono, Tetsuya published the artcileElectrocatalytic Oxidation of Carbohydrates Mediated by Nitroxyl Radical-Modified Electrodes in Aqueous Solution, Application of 3-(1H-Pyrrol-1-yl)propan-1-ol, the main research area is electrocatalysis oxidation carbohydrate mediated nitroxyl radical modified electrode.

The electrocatalytic activity of a 2,2,6,6-tetramethylpipridine-N-oxyl (TEMPO)-modified electrode toward the oxidation of carbohydrates in phosphate buffer solution was studied under neutral aqueous solution conditions at 25°. The modified electrode was prepared on the surface of a glassy C electrode by the electrochem. polymerization of a TEMPO precursor containing a pyrrole side chain. Cyclic voltammetric studies showed that the anodic peak current increased with the concentration of carbohydrates in a dose-dependent manner.

Electroanalysis published new progress about Chemically modified electrodes. 50966-69-3 belongs to class alcohols-buliding-blocks, name is 3-(1H-Pyrrol-1-yl)propan-1-ol, and the molecular formula is C7H11NO, Application of 3-(1H-Pyrrol-1-yl)propan-1-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Opsomer, Tomas published the artcile1,2,3-Triazole-Mediated Synthesis of 1-Methyleneisoquinolines: A Three-Step Synthesis of Papaverine and Analogues, HPLC of Formula: 22483-09-6, the main research area is methyleneisoquinoline preparation heterocyclization Pomeranz Fritsch reaction; papaverine analog preparation.

A metal-free three-step synthesis toward functionalized 1-methyleneisoquinolines from readily available substrates is reported. First, acetal-containing 1,2,3-triazoles were prepared via a high-yielding triazole formation reaction and quant. converted into triazolo[5,1-a]isoquinolines. Next, the acid-promoted ring opening of these fused triazoles was studied in order to obtain coupling to a diverse scope of nucleophiles, including carbon nucleophiles such as veratrole. By means of non-nucleophilic strong acids under anhydrous conditions, a series of unprecedented isoquinolines and imidazo[5,1-a]isoquinolines was synthesized.

Organic Letters published new progress about Heterocyclization. 22483-09-6 belongs to class alcohols-buliding-blocks, name is 2,2-Dimethoxyethanamine, and the molecular formula is C4H11NO2, HPLC of Formula: 22483-09-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Packiaraj, S. published the artcileDifferent coordination geometries of lighter lanthanates driven by the symmetry of guanidines as charge compensators, Synthetic Route of 110-99-6, the main research area is crystal structure guanidinium lanthanide thiodiacetate oxydiacetate preparation luminescence.

Two new related families (GunH)3[Ln(tda)3] I and (AgunH)3[Ln(oda)3]·H2O II (Ln = La, Ce, Pr, Nd and Sm, H2tda = thiodiacetic acid, H2oda = oxydiacetic acid, GunH = guanidinium, AgunH = aminoguanidinium) were successfully synthesized using a controlled process under oil-bath conditions (at 120° for a day) and characterized by various physicochem. techniques. The structures were solved for Pr and Nd in I and for La in II, resp., from x-ray diffraction data of single crystals. The isostructural complexes of (GunH)3[Pr(tda)3] and (GunH)3[Nd(tda)3] crystallize in the hexagonal crystal system with space group P6̅2c, while (AgunH)3[La(oda)3]·H2O has a triclinic symmetry with the P1̅ space group. Generally, coordination number 6 (octahedral) and 4 (tetrahedral) structures are very rare except when bulky ligands are present. Typically, the thiodiacetate (O,S,O) and oxydiacetate (O,O,O) anions act as tridentate ligands to create monomeric structures. Surprisingly, for the 1st time, the thiodiacetate anion takes a somewhat rare bidentate (O,O) mode, leading to trigonal prismatic geometry around the metal ion even for a flexible ligand, whereas the oxydiacetate dianion (oda2-) acquires the usual nine coordinated distorted monocapped square anti-prismatic (MSAP) geometry. The simultaneous TG-DTA I complexes could not be recorded due to spurting, while the type II compounds show smooth and similar thermal behavior on heating. The photoluminescent properties of I and II were studied at room temperature, which indicate that the emissions come from intra-ligand π-π* transitions.

New Journal of Chemistry published new progress about Crystal structure. 110-99-6 belongs to class alcohols-buliding-blocks, name is 2,2′-Oxydiacetic acid, and the molecular formula is C4H6O5, Synthetic Route of 110-99-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Cui, Hui-Ya published the artcileEngineering noble-metal-free metal-organic framework composite catalyst for efficient CO2 conversion under ambient conditions, COA of Formula: C8H14O, the main research area is copper bromide zeolite catalyst CO2 propargylamine propargyl alc cycloaddition.

The cyclization of propargylic alcs. and propargylic amines with CO2 are of great significance since the generated O/N-containing cyclic skeletons are extensively employed in pharmaceutical chem. and industrial production However, most of the reported catalysts only effectively catalyze propargylic alcs. or propargylic amines with CO2, and often involve noble-metal catalysts, high temperature and CO2 pressure. It is a great challenge that non-noble-metal catalysts catalyzed both propargylic alcs. and propargylic amines with CO2 under ambient conditions. Herein, CuBr@NH2-MIL-101 was successfully synthesized by loading CuBr nanoparticles into zeolite-type NH2-MIL-101 via simple thermal conversion method, and it displayed highly selective CO2 uptake properties. Importantly, CuBr@NH2-MIL-101 featured high catalytic activity for carboxylative cyclization of both propargylic alcs. and propargylic amines with CO2 under ambient conditions (25°C, 0.1 MPa CO2), resp. Moreover, CuBr@NH2-MIL-101 can be recycled at least three times without significant decline in catalytic activity. The combination explorations of NMR, FTIR and 13C isotope labeling experiments clearly illustrate the reaction process and mechanism. The d. functional theory (DFT) calculations uncover that CuBr and 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) can synergistically activate substrates, and the proton-demetalation step with the highest energy barrier was the rate-determining step in two catalytic systems. To our knowledge, it is the first report of noble-metal-free catalyst that can simultaneously catalyze CO2 conversion with propargylic alcs. and propargylic amines under room temperature and atm. CO2 pressure.

Chemical Engineering Journal (Amsterdam, Netherlands) published new progress about Amines, propargyl Role: PEP (Physical, Engineering or Chemical Process), PRP (Properties), RCT (Reactant), PROC (Process), RACT (Reactant or Reagent). 107-54-0 belongs to class alcohols-buliding-blocks, name is 3,5-Dimethylhex-1-yn-3-ol, and the molecular formula is C8H14O, COA of Formula: C8H14O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Gao, Xianli published the artcileEnhancing selenium and key flavor compounds contents in soy sauce using selenium-enriched soybean, Recommanded Product: 3-(Methylthio)propan-1-ol, the main research area is soybean soy sauce selenium flavor.

Selenium (Se) deficiency has become a global health threat. Se-enriched soybean was utilized to develop a Se-enriched soy sauce (SeSS), and the effects of Se-enriched soybean on the flavor compounds in SeSS were characterized with HPLC and SPME-GC-olfactometry/MS. Results showed that the contents of total selenium (11.1-fold), organic selenium (10.6-fold), small peptides (≤1 kDa, 25.4%), free amino acids (FAAs, 8.67%) and 22 aroma-active compounds in SeSS were significantly enhanced when compared to soy sauce prepared using ordinary soybean (SS, p < 0.05). Only the contents of 4-vinylguaiacol and acetic acid in SeSS were decreased by 30.5% and 17.7%. Further investigations found that Se-enriched soybean markedly enhanced the activities of acidic and alk. proteases in the koji and moromi (p < 0.05), which made more proteins and large peptides degrade into small peptides, sweet and bitter FAAs. Se-enriched soybean moromi promoted the reproduction of aroma-producing Lactobacillus plantarum and Zygosaccharomyces rouxii, and more aroma-active compounds were detected in SeSS. 4-Vinylguaiacol was reduced to 4-ethylguaiacol by L. plantarum and acetic acid was converted into acetate via esterification. The work developed a widely accessible selenium supplement and a novel method to improve the flavor of soy sauce. Journal of Food Composition and Analysis published new progress about Alcohols Role: ANT (Analyte), BSU (Biological Study, Unclassified), FFD (Food or Feed Use), ANST (Analytical Study), BIOL (Biological Study), USES (Uses). 505-10-2 belongs to class alcohols-buliding-blocks, name is 3-(Methylthio)propan-1-ol, and the molecular formula is C4H10OS, Recommanded Product: 3-(Methylthio)propan-1-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Song, Young-Kyu published the artcileRepeatable Self-Healing of a Protective Coating Based on Vegetable-Oil-Loaded Microcapsules, SDS of cas: 111-87-5, the main research area is vegetable oil loaded microcapsule self healing protective coating; microcapsule; olive oil; protective coating; repeatable self-healing; soybean oil; viscoelasticity.

Generally, microcapsule-based self-healing materials have the limitation of single local self-healing. A few studies have reported repeatable self-healing in these microcapsular materials, but there is a challenge to develop multi-cycle self-healing materials that have the advantages of easier preparation and a more efficient operation. In this work, a mixture of two vegetable oils, soybean and olive oil, was used as a healing agent. The atm. oxygen-induced reaction behavior (in the presence of a catalyst) was investigated for various compositions of the vegetable oil mixtures; IR spectroscopy, recovery testing, and viscoelasticity measurement were performed to find an optimum composition of the healing agent. Microcapsules loaded with soybean oil and catalyst-containing olive oil were sep. prepared and used to prepare a dual-capsule self-healing coating. It was demonstrated through optical and SEM that, upon scribing the self-healing coating, the vegetable oils flowed out from microcapsules to self-heal the damaged area. When the healed area of the self-healing coating was re-scribed, self-healing was repeated, which was confirmed by SEM (SEM) and anticorrosion and electrochem. testing. Our new repeatable self-healing coating provides the merits of easy preparation, no need for external intervention such as light irradiation, and an environmentally-friendly nature.

Polymers (Basel, Switzerland) published new progress about Anticorrosive coating materials. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, SDS of cas: 111-87-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Paupiere, Marine J. published the artcileThe effect of isolation methods of tomato pollen on the results of metabolic profiling, HPLC of Formula: 97-67-6, the main research area is Solanum pollen grain metabolomics homogenization reproducibility lyophilization flavonoid phenylpropanoid; Anther; Metabolite; Metabolome; Metabolomics; Pollen; Tomato.

Untargeted metabolomics is a powerful tool to detect hundreds of metabolites within a given tissue and to compare the metabolite composition of samples in a comprehensive manner. However, with regard to pollen research such comprehensive metabolomics approaches are yet not well developed. To enable isolation of pollen that is tightly enclosed within the anthers of the flower, such as immature pollen, the current pollen isolation protocols require the use of a watery solution These protocols raise a number of concerns for their suitability in metabolomics analyses, in view of possible metabolic activities in the pollen and contamination with anther metabolites. We assessed the effect of different sample preparation procedures currently used for pollen isolation for their suitability to perform metabolomics of tomato pollen. Pollen were isolated using different methods and the metabolic profiles were analyzed by liquid chromatog.-mass spectrometry (LC-MS). Our results demonstrated that pollen isolation in a watery solution led to (i) rehydration of the pollen grains, inducing marked metabolic changes in flavonoids, phenylpropanoids and amino acids and thus resulting in a metabolite profile that did not reflect the one of mature dry pollen, (ii) hydrolysis of sucrose into glucose and fructose during subsequent metabolite extraction, unless the isolated and rehydrated pollen were lyophilized prior to extraction, and (iii) contamination with anther-specific metabolites, such as alkaloids, thus compromising the metabolic purity of the pollen fraction. We conclude that the current practices used to isolate pollen are suboptimal for metabolomics analyses and provide recommendations on how to improve the pollen isolation protocol, in order to obtain the most reliable metabolic profile from pollen tissue.

Metabolomics published new progress about Alkaloids Role: ANT (Analyte), BSU (Biological Study, Unclassified), ANST (Analytical Study), BIOL (Biological Study). 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, HPLC of Formula: 97-67-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts