Tag: M.W=100-150

Sirtori, Francesco published the artcileEffects of genotype and salting time on chemical, physical and sensorial traits of a new pig seasoned meat product ‘Cuore Di Spalla’, Safety of 3-(Methylthio)propan-1-ol, the main research area is Cuore Di Spalla genotype sensory property food.

The aim of this work was to determine the chem., phys. and sensorial characteristics of a cured product called ‘Cuore di Spalla’, resulting from two different pig genotypes (G) and two salting times (S). Fourteen Duroc × Large White (D × LW) and 14 Cinta Senese × Large White (CS × LW), reared in the same condition in outdoor and fed com. mixture The animals were slaughtered at 10 mo of age which corresponds to an average live weight of 143 ± 15 kg for D × LW and 122 ± 15 kg for CS × LW. The right shoulders were salted for 3 days (L) and the left ones for 5 days (H). Phys. (color, texture profile anal.), chem. (moisture; crude protein; IMF; ash; salt; total lipids; fatty acids) and sensorial analyses (by panellists’ group) as well as volatile compounds profile (by SPME-GC-MS technique) were determined at the end of seasoning period. The genotype affected product’s size (1484.3 vs 1857.1 g of final weight for CS × LW and D × LW resp.), chem. characteristics and texture (cohesiveness 0.50 vs 0.53 and springiness 6.73 vs 7.12 for CS × LW and D × LW resp.). Aromatic profile was less affected by the factors considered or at least the panellists were not able to discriminate the effect. The main family of volatile compounds affected by genotype was alcs. Salting time seemed to affect only the parameters closely related to salt (16.52 vs 15.33% of salt and 5.15 vs 4.35 for saltiness in H vs L resp.).

Italian Journal of Animal Science published new progress about Fatty acids Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 505-10-2 belongs to class alcohols-buliding-blocks, name is 3-(Methylthio)propan-1-ol, and the molecular formula is C4H10OS, Safety of 3-(Methylthio)propan-1-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Niu, Feng published the artcileAlcohol amination over titania-supported ruthenium nanoparticles, Application In Synthesis of 111-87-5, the main research area is alc amination titania supported ruthenium nanoparticle.

Metal nanoparticles for heterogeneous catalytic reactions are often supported on porous materials. The catalytic performance of supported catalysts usually depends on the size of the metal nanoparticles and catalytic supports. Selective synthesis of valuable primary amines is an important target in the modern industry. In this work, the catalytic performance of TiO2 supported Ru nanoparticles with sizes from 1.4 to 9.9 nm was investigated in both direct gas-phase amination of 1-butanol and liquid-phase amination of 1-octanol into primary amines in the presence of ammonia. Our results suggest that ruthenium nanoparticle size is one of the most important parameters, which affects the catalytic performance of titania supported catalysts in the amination reactions. The selectivity to primary amines is much higher over smaller supported Ru nanoparticles than over larger ones, especially in the liquid-phase amination of 1-octanol. The 95% selectivity to octylamine is obtained over small supported Ru nanoparticles with a diameter of 1.4 nm even at 95% conversion, whereas for larger Ru nanoparticles, the octylamine selectivity drops as the 1-octanol conversion approached 80-90%. The drop of the selectivity to octylamine at higher conversion is due to the increase in the intrinsic rate of octylamine coupling over larger ruthenium nanoparticles. The support can also contribute to some extent to the rate of primary amine self-coupling, while its effect on the overall catalytic performance is not significant for the titania-supported catalysts.

Catalysis Science & Technology published new progress about Alcohols Role: PEP (Physical, Engineering or Chemical Process), PROC (Process). 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Application In Synthesis of 111-87-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Hadian, Mojgan published the artcileSustainability by design: automated nanoscale 2,3,4-trisubstituted quinazoline diversity, Safety of 2,2-Dimethoxyethanamine, the main research area is formyl acid preparation amine isocyanide Ugi reaction; amido carboxyquinazoline preparation.

The synthetic execution of a newly designed quinazoline reaction towards a transformative sustainability in chem. was exemplified. This included nanoscale synthesis, deep chem. space exploration, scalability over 6 orders of magnitude from milligram up to 10-g resynthesis of quinazolines enabled by the simultaneous variation of four classes of building blocks. Benefits of our approach include a simple to perform, one-step procedure, mild reaction conditions and access to a very large chem. space through accessing many available building blocks. More than thousand derivatives were produced in an automated fashion on a nanoscale using pos. pressure facilitated dispensing. Along with these advantages, there is a considerable reduction in synthetic effort, reagents, solvent, glass and plastic consumables and power consumption to decrease the footprint of synthetic chem.

Green Chemistry published new progress about Amides Role: PRP (Properties), SPN (Synthetic Preparation), PREP (Preparation). 22483-09-6 belongs to class alcohols-buliding-blocks, name is 2,2-Dimethoxyethanamine, and the molecular formula is C4H11NO2, Safety of 2,2-Dimethoxyethanamine.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Briz-Cid, Noelia published the artcileInfluence of tetraconazole on the proteome profile of Saccharomyces cerevisiae Lalvin T73 strain, Application of 3-(Methylthio)propan-1-ol, the main research area is proteome grape wine tetraconazole stress response Saccharomyces; Amino acid and purine biosynthesis; Ergosterol biosynthesis; Multidrug resistance; Proteome profile; Putative transcription factors; Stress response.

This work aimed to evaluate the modifications on the proteome profile of Saccharomyces cerevisiae T73 strain as a consequence of its adaptive response to the presence of tetraconazole mols. in the fermentation medium. Pasteurised grape juices were sep. supplemented with tetraconazole or a com. formulation containing 12.5% w/v of tetraconazole at two concentration levels. In addition, experiments without fungicides were developed for comparative purposes. Proteome profiles of yeasts cultured in the presence or absence of fungicide mols. were different. Independently of the fungicide treatment applied, the highest variations concerning the control sample were observed for those proteins involved in metabolic processes, especially in the metabolism of nitrogen compounds Tetraconazole mols. altered the abundance of several enzymes involved in the biosynthesis of amino acids, purines, and ergosterol. Moreover, differences in the abundance of several enzymes of the TCA cycle were found. Changes observed were different between the active substance and the com. formulation. The presence of fungicide residues in grape juice has direct implications on the development of the aromatic profile of the wine. These alterations could be related to changes in the secondary metabolism of yeasts. However, the mol. mechanisms involved in the response of yeasts to fungicide residues remains quite unexplored. Through this exhaustive proteomic study, alterations in the amino acids biosynthesis pathways due to the presence of the tetraconazole mols. were observed Amino acids are precursors of some important higher alcs. and Et acetates (such as methionol, 2-phenylethanol, isoamyl alc. or 2-phenylacetate). Besides, the effect of tetraconazole on the ergosterol biosynthesis pathway could be related to a higher production of medium-chain fatty acids and their corresponding Et acetates.

Journal of Proteomics published new progress about Amino acids Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 505-10-2 belongs to class alcohols-buliding-blocks, name is 3-(Methylthio)propan-1-ol, and the molecular formula is C4H10OS, Application of 3-(Methylthio)propan-1-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Boettcher, C. published the artcilePost-veraison restriction of phloem import into Riesling (Vitis vinifera L.) berries induces transient and stable changes to fermentation-derived and varietal wine volatiles, Related Products of alcohols-buliding-blocks, the main research area is Vitis phloem import wine volatile fermentation.

Background and Aims : The climate-change driven uncoupling of grape (Vitis vinifera L.) berry ‘sugar-ripeness’ and ‘flavor-ripeness’ necessitates an improved understanding of the sugar/flavor nexus. Methods and Results : Anal. of grape metabolites and wine volatiles derived from Riesling berries of peduncle-girdled and Control bunches over the course of 30 days provided time-dependent insights into changes to grape and wine composition associated with phloem import. Girdling resulted in stable berry mass and concentration of sugar and cytokinin and in reduced concentration of amino acids. Such changes to grape composition correlated with a lasting increase in wine monoterpenoids and a transient reduction in fermentation-derived wine volatiles. Conclusions : Oxidative stress and restricted amino acid import, not sugar accumulation, were identified as possible elicitors for the increased accumulation of varietal wine aroma compounds in Riesling. Significance of the Study : The concentration and composition of berry amino acids and cytokinin concentration in grapes during the later stages of rapid sugar accumulation may represent potential targets for vineyard management strategies and grapevine breeding to counter climate-change driven modifications to the wine volatile profile of aromatic cultivars.

Australian Journal of Grape and Wine Research published new progress about Amino acids Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 505-10-2 belongs to class alcohols-buliding-blocks, name is 3-(Methylthio)propan-1-ol, and the molecular formula is C4H10OS, Related Products of alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Gao, Yaping published the artcilePhotosynthetic and metabolic responses of eelgrass Zostera marina L. to short-term high-temperature exposure, Application In Synthesis of 97-67-6, the main research area is zostera photosynthetic physiol metabolic response temperature membrane system.

In recent years, extreme heat events have occurred worldwide and the ocean temperature has been rising, causing stress on the photosynthesis and growth of seagrass. Metabolomics enables detection of metabolic changes under environmental stress. In this study, the photosynthetic physiol. and metabolic changes of the eelgrass Zostera marina L. in response to 48 h exposure to 32°C were investigated. The results showed that high temperature induced significant inhibition of photosynthetic efficiency (Δ F / F’m ) (23.9% lower than the control), enhanced respiration (58.3% higher), and decreased carbohydrate decomposition products and tricarboxylic acid (TCA) cycle intermediate products, indicating that the energy supply of the eelgrass may be insufficient at high temperature In addition, high temperature decreased stearic acid and linoleic acid in eelgrass, suggesting the composition of the membrane system of eelgrass may change at high temperature and implying that high temperature may cause the membrane system to be unstable.

Journal of Oceanology and Limnology published new progress about Amino acids Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Application In Synthesis of 97-67-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Lema, Kimberley A. published the artcileInter- and intra-specific transcriptional and phenotypic responses of Pseudo-nitzschia under different nutrient conditions, Safety of (S)-2-hydroxysuccinic acid, the main research area is Pseudo nitzschia transcription phenotype nutrient; Pseudo-nitzschia ; divergence; nutrients; phenotype; transcriptomics.

Untangling the functional basis of divergence between closely related species is a step toward understanding species dynamics within communities at both the evolutionary and ecol. scales. We investigated cellular (i.e., growth, domoic acid production, and nutrient consumption) and mol. (transcriptomic analyses) responses to varying nutrient concentrations across several strains belonging to three species of the toxic diatom genus Pseudo-nitzschia. First, strains from the same species displayed similar transcriptomic, but not necessarily cellular, responses to the exptl. conditions. It showed the importance of considering intraspecific diversity to investigate functional divergence between species. Second, a major exception to the first finding was a strain recently isolated from the natural environment and displaying contrasting gene expression patterns related to cell motility and domoic acid production This result illustrated the profound modifications that may occur when transferring a cell from the natural to the in vitro environment and asks for future studies to better understand the influence of culture duration and life cycle on expression patterns. Third, transcriptomic responses were more similar between the two species displaying similar ecol. in situ, irresp. of the genetic distance. This was especially true for mol. responses related to TCA cycle, photosynthesis, and nitrogen metabolism However, transcripts related to phosphate uptake were variable between species.

Genome Biology and Evolution published new progress about Amino acids Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Safety of (S)-2-hydroxysuccinic acid.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Brizuela, N. S. published the artcileInfluence of Patagonian Lactiplantibacillus plantarum and Oenococcus oeni strains on sensory perception of Pinot Noir wine after malolactic fermentation, Category: alcohols-buliding-blocks, the main research area is Lactiplantibacillus Oenococcus Pinot Noir wine sensory perception malolactic fermentation.

Background and Aims : The aim of this work was to study the effect of two Patagonian malolactic starters, Oenococcus oeni UNQOe 73.2 and Lactiplantibacillus plantarum UNQLp 11, on the wine composition and sensory perception after MLF of Pinot Noir wine. Methods and Results : Both strains increased the concentration of procyanidin, diminished the concentration of phenolic substances and increased the color intensity of the wine after MLF. The volatile profile of both strains differed to that of the Control, particularly the esters, vanillin and some terpenes. The attributes acidity and astringency, black and dried fruits and spicy attributes were features of the wine fermented with both strains. Conclusions : Both strains were able to conduct MLF, to increase color intensity and to change the flavor of the wine with some differences. The wine fermented with UNQLp 11 had a greater frequency of bitterness, whereas the wine fermented with UNQOe 73.2 had a greater frequency of butter. Significance of the Study : Knowledge of the effect of Patagonian starter cultures on consumer perception of the wine after fermentation has been improved.

Australian Journal of Grape and Wine Research published new progress about Amino acids Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Diebold, Lauren P. published the artcileMitochondrial complex III is necessary for endothelial cell proliferation during angiogenesis, Computed Properties of 97-67-6, the main research area is endothelial cell proliferation mitochondrial complex III angiogenesis.

Abstract: Endothelial cells (ECs) require glycolysis for proliferation and migration during angiogenesis; however, the necessity for the mitochondrial respiratory chain during angiogenesis is not known. Here we report that inhibition of respiratory chain complex III impairs proliferation, but not migration, of ECs in vitro by decreasing the NAD+/NADH ratio. To determine whether mitochondrial respiration is necessary for angiogenesis in vivo, we conditionally ablate a subunit of the respiratory chain complex III (QPC) in ECs. Loss of QPC decreases respiration, resulting in diminished EC proliferation, and impairment in retinal and tumor angiogenesis. Loss of QPC does not decrease genes associated with anabolism or nucleotide levels in ECs but diminishes amino acid levels. Our findings indicate that mitochondrial respiration is necessary for angiogenesis and that the primary role of mitochondria in ECs is to serve as biosynthetic organelles for cell proliferation.

Nature Metabolism published new progress about Amino acids Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Computed Properties of 97-67-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Tedesco, Laura published the artcileAn original amino acid formula favours in vitro corneal epithelial wound healing by promoting Fn1, ITGB1, and PGC-1α expression, Recommanded Product: (S)-2-hydroxysuccinic acid, the main research area is fibronectin1 integrin beta1 peroxisome proliferator receptor gamma coactivator1 alpha; integrin beta1 invitro corneal epithelial wound healing; Amino acids; Cell migration; Corneal epithelial cells; Fibronectin; Integrin; PGC 1α.

Corneal disorders are frequent, involving most diabetic patients; among its manifestations, they include delayed wound healing. Since maintenance of mitochondrial homeostasis is fundamental for the cell, stimulation of mitochondrial biogenesis represents a unique therapeutic tool for preventing and treating disorders with a deficit in energy metabolism We have recently demonstrated that a branched-chain amino acid (BCAA)-enriched mixture (BCAAem) supported mitochondrial biogenesis in cardiac and skeletal muscle, reduced liver damage caused by alc., and prevented the doxorubicin-dependent mitochondrial damage in cardiomyocytes. The present study aimed to investigate a new amino acid mixture, named six amino acids (6AA), to promote corneal epithelial wound healing by regulating mitochondrial biogenesis. A murine epithelium cell line (TKE2) exposed to this mixture showed increased mitochondrial biogenesis markers, fibronectin 1 (Fn1) and integrin beta 1 (ITGB1) involved in extracellular matrix synthesis and cell migration. Most importantly, the 6AA mixture completely restored the wound in scratch assays, confirming the potential of this new formula in eye disorders like keratopathy. Moreover, our results demonstrate for the first time that peroxisome proliferator-receptor γ coactivator 1 α (PGC-1α) is expressed in TKE2 cells, which controls mitochondrial function and corneal repair process. These results could be relevant for the treatment mainly focused on corneal re-epithelialisation.

Experimental Eye Research published new progress about Amino acids Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Recommanded Product: (S)-2-hydroxysuccinic acid.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts