Tag: M.W=100-150

Nguyen, Bidong D. published the artcileImport of Aspartate and Malate by DcuABC Drives H2/Fumarate Respiration to Promote Initial Salmonella Gut-Lumen Colonization in Mice, Synthetic Route of 97-67-6, the main research area is import aspartate malate dcuabc drive fumarate respiration promote initial; salmonella gut lumen colonization mice; Salmonella; infection; intestine; metabolism; mouse model.

Initial enteropathogen growth in the microbiota-colonized gut is poorly understood. Salmonella Typhimurium is metabolically adaptable and can harvest energy by anaerobic respiration using microbiota-derived hydrogen (H2) as an electron donor and fumarate as an electron acceptor. As fumarate is scarce in the gut, the source of this electron acceptor is unclear. Here, transposon sequencing anal. along the colonization trajectory of S.Typhimurium implicates the C4-dicarboxylate antiporter DcuABC in early murine gut colonization. In competitive colonization assays, DcuABC and enzymes that convert the C4-dicarboxylates aspartate and malate into fumarate (AspA, FumABC), are required for fumarate/H2-dependent initial growth. Thus, S. Typhimurium obtains fumarate by DcuABC-mediated import and conversion of L-malate and L-aspartate. Fumarate reduction yields succinate, which is exported by DcuABC in exchange for L-aspartate and L-malate. This cycle allows S.Typhimurium to harvest energy by H2/fumarate respiration in the microbiota-colonized gut. This strategy may also be relevant for commensal E. coli diminishing the S.Typhimurium infection.

Cell Host & Microbe published new progress about Electron acceptors. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Synthetic Route of 97-67-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kucharska, Jarmila published the artcileTreatment with coenzyme Q10, ω-3-polyunsaturated fatty acids and their combination improved bioenergetics and levels of coenzyme Q9 and Q10 in skeletal muscle mitochondria in experimental model of arthritis, SDS of cas: 97-67-6, the main research area is COQ10 omega3PUFA antiarthritic agent mitochondrial bioenergetics adjuvant arthritis.

Rheumatoid arthritis (RA) and its animal model adjuvant arthritis (AA) are inflammatory diseases characterized by chronic inflammation, systemic oxidative stress and disturbed mitochondrial bioenergetics of skeletal muscle. The present study aimed to evaluate the effects of coenzyme Q10 – CoQ10 (100 mg/kg b.w.), omega-3-polyunsaturated fatty acids – ω-3-PUFA (400 mg/kg b.w.) and their combined treatment in AA on impaired skeletal muscle mitochondrial bioenergetics, inflammation and changes in levels CoQ9 and CoQ10 in plasma. Markers of inflammation (C-reactive protein, monocytechemotactic protein-1), antioxidant capacity of plasma, respiratory chain parameters of skeletal muscle mitochondria and concentrations of CoQ9 and CoQ10 in plasma and in muscle tissue were estimated Treatment of the arthritic rats with CoQ10, ω-3-PUFA alone and in combination partially reduced markers of inflammation and increased antioxidant capacity of plasma, significantly increased concentrations of coenzyme Q in mitochondria and improved mitochondrial function in the skeletal muscle. Combined treatment has similar effect on the mitochondrial function as monotherapies; however, it has affected inflammation and antioxidant status more intensively than monotherapies. Long-term supplementary administration of coenzyme Q10 and ω-3-PUFA and especially their combination is able to restore the impaired mitochondrial bioenergetics and antioxidant status in AA.

Physiological Research (Prague, Czech Republic) published new progress about Adjuvant arthritis. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, SDS of cas: 97-67-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Xu, Lei published the artcileEffects of high-temperature pre-drying on the quality of air-dried shiitake mushrooms (Lentinula edodes), Quality Control of 505-10-2, the main research area is Lentinula drying ketone aldehyde; Formaldehyde; High-temperature pre-drying; Shiitake mushroom.

We investigated the relationship between the pre-drying temperature and overall quality of dried shiitake mushrooms (Lentinula edodes). Results showed that high-temperature pre-drying significantly increased the rehydration ratio and hardness of dried shiitake mushrooms, but decreased the degree of shrinkage, degree of browning, and formaldehyde content. The levels of enzyme activity were high throughout the pre-drying process and benefitted the formation of flavoured substances. Furthermore, high-temperatures pre-drying also resulted in a higher content of sulfur compounds These results indicated that the pre-drying processing had significant impacts on the overall quality of dried shiitake mushrooms. This may pave the way for increasing the economic value of dried shiitake mushrooms.

Food Chemistry published new progress about Air drying process. 505-10-2 belongs to class alcohols-buliding-blocks, name is 3-(Methylthio)propan-1-ol, and the molecular formula is C4H10OS, Quality Control of 505-10-2.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kazmierczak, Kamila published the artcileActivity of heterogeneous supported Cu and Ru catalysts in acceptor-less alcohol dehydrogenation, Application In Synthesis of 111-87-5, the main research area is copper ruthenium alc dehydrogenation catalyst.

Acceptor-less alc. dehydrogenation reaction allows the co-production of added-value carbonyl compounds and H2 from alcs. Focusing on supported Ru and Cu catalysts, we evaluated the support effect on the dehydrogenation of 2-octanol and 1-octanol and identified the side products as resulting from aldolisation coupling. The most active and selective catalysts were then tested on the aliphatic vicinal-diol octan-1,2-diol and the highest conversion was reached using Cu/ZrO2 (60%) with a high selectivity (94%) towards 1-hydroxy-2-octanone.

Catalysis Communications published new progress about Aldol condensation. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Application In Synthesis of 111-87-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kazmierczak, Kamila published the artcileSupported Cobalt Catalysts for Acceptorless Alcohol Dehydrogenation, Related Products of alcohols-buliding-blocks, the main research area is cobalt catalyst acceptorless alc dehydrogenation; TiO2; acceptorless alcohol dehydrogenation; cobalt; heterogeneous catalysis; supported catalysts.

The acceptor-less dehydrogenation of 2-octanol was tested over cobalt supported on Al2O3, C, ZnO, ZrO2 and various TiO2 substrates. The catalysts were characterized by ICP, XRD and TGA-H2. For Co/TiO2 P25, the effects of passivation, aging (storage at room temperature), and in situ activation under H2 were investigated. The catalysts must be tested shortly after synthesis in order to prevent deactivation. Cobalt supported on TiO2 P25 was the most active and 69% yield of 2-octanone was obtained, using decane as a solvent. Selectivities for 2-octanone were observed in the range of 90% to 99.9%. Small amounts of C16 compounds were also formed due to aldol condensation/dehydration reactions. The catalysts exhibited higher conversion in the dehydrogenation of secondary alcs. (65-69%), in comparison to primary alcs. (2-10%). The dehydrogenation of 1,2-octanediol led to 1-hydroxy-2-octanone, with a selectivity of 90% and 69% for Co/TiO2 P25 and Co/TiO2 P90, resp.

ChemPlusChem published new progress about Aldol condensation. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Related Products of alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kubisch, Christin published the artcileValorization of a Pyrolytic Aqueous Condensate and Its Main Components for L-Malic Acid Production with Aspergillus oryzae DSM 1863, Product Details of C4H6O5, the main research area is Aspergillus malic acid valorization pyrolytic aqueous condensate.

Pyrolytic aqueous condensate (PAC) might serve as a cost-effective substrate for microbial malic acid production, as it is an unused side stream of the fast pyrolysis of lignocellulosic biomass that contains acetol and acetate as potential carbon sources. In the present study, shake flask cultures were performed to evaluate the suitability of acetol and its combination with acetate as substrates for growth and L-malate production with the filamentous fungus Aspergillus oryzae. Acetol concentrations of up to 40 g/L were shown to be utilized for fungal growth. In combination with acetate, co-metabolization of both substrates for biomass and malate formation was observed, although the maximum tolerated acetol concentration decreased to 20 g/L. Furthermore, malate production on PAC detoxified by a combination of rotary evaporation, overliming and activated carbon treatment was studied. In shake flasks, cultivation using 100% PAC resulted in the production of 3.37 ± 0.61 g/L malate, which was considerably improved by pH adjustment up to 9.77 ± 0.55 g/L. A successful scale-up to 0.5-L bioreactors was conducted, achieving comparable yields and productivities to the shake flask cultures. Accordingly, fungal malate production using PAC was successfully demonstrated, paving the way for a bio-based production of the acid.

Fermentation published new progress about Aspergillus oryzae. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Product Details of C4H6O5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wanyan, Qianru published the artcileTuning Degradation and Mechanical Properties of Poly(l-lactic acid) with Biomass-Derived Poly(l-malic acid), Safety of (S)-2-hydroxysuccinic acid, the main research area is polymalic acid PLLA blend morphol mech thermal property.

Poly(l-malic acid) (PLMA) oligomer was used as the minor phase to prepare the blends with poly(l-lactic acid) (PLLA), with the objective to develop fully biomass-derived and biodegradable aliphatic polyester blends with balanced overall performance. The phase behavior and viscoelastic responses reveals that the two phases are thermodynamically immiscible, showing high level of interfacial tension in their blends. Poor phase adhesion and lower mass weight of PLMA results in an evident decrease of mech. properties of the blends as compared to PLLA. The dilute effect caused by the addition of PLMA, however, promotes the cold crystallization of PLLA. Therefore, the strength and modulus losses of the blends can be remedied well by the annealing in solid state. Besides, the degradation rates can also be regulated by the presence of hydrophilic PLMA phase. In this case, a fully green PLLA/PLMA blend with balanced properties is fabricated. This work also provides useful information developing new applications of PLMA.

Journal of Polymers and the Environment published new progress about Adhesion, physical. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Safety of (S)-2-hydroxysuccinic acid.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wu, Shuanggen published the artcileDeep Eutectic Supramolecular Polymers: Bulk Supramolecular Materials, Formula: C4H6O5, the main research area is deep eutectic supramol polymer bulk; deep eutectic solvents; materials science; polymers; self-assembly; supramolecular chemistry.

Application of new strategies for supramol. self-assembly can significantly impact the properties and/or functions of supramol. polymers. To realize a facial strategy for the development of solvent-free supramol. polymers in bulk, “”deep eutectic solvents”” were employed. Cyclodextrins and natural acids were used to prepare deep eutectic supramol. polymers (DESPs). Deep eutectic solvents have special characteristics that endow DESPs with unique macroscopic properties and excellent processability. DESPs exhibit supramol. adhesion and temperature-dependent behavior originating from the combined effects of deep eutectic solvents and supramol. polymerization Because DESPs are solvent-free and display interesting macroscopic properties, they have potential as new adaptive materials.

Angewandte Chemie, International Edition published new progress about Adhesion, physical. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Formula: C4H6O5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Azadi, Mehdi published the artcileThe Effect of Dissolved Gases on the Short-Range Attractive Force between Hydrophobic Surfaces in the Absence of Nanobubble Bridging, Product Details of C8H18O, the main research area is force hydrophobic surface gas solubility.

The short-range attractive forces between hydrophobic surfaces are key factors in a wide range of areas such as protein folding, lipid self-assembly, and particle-bubble interaction such as in industrial flotation. Little is certain about the effect of dissolved (well-controlled) gases on the interaction forces, in particular in those systems where the formation of surface nanobubble bridges is suppressed. Here, we probe the short-range attractive force between hydrophobized silica surfaces in aqueous solutions with varying but well-controlled isotherms of gas solubility The first contact approach force measurement method using AFM shows that decreasing gas solubility results in a decrease of the force magnitude as well as shortening of its range. The behavior was found to be consistent across all four aqueous systems and gas solubilities tested. Using numerical computations, we corroborate that attractive force can be adequately explained by a multilayer dispersion force model, which accounts for an interfacial gas enrichment (IGE), that results in the formation of a dense gas layer (DGL) adjacent to the hydrophobic surface. We found that the DGL on the hydrophobic surface is affected only by the concentration of dissolved gases and is independent of the salt type, used to control the gas solubility, which excludes the effect of elec. double-layer interactions on the hydrophobic force.

Langmuir published new progress about Dielectric constant. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Product Details of C8H18O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Reedy, E. D. Jr. published the artcileInterfacial toughness: dependence on surface roughness and test temperature, COA of Formula: C4H11NO2, the main research area is aluminum epoxy interface surface roughness temperature.

Abstract: Interfacial toughness quantifies resistance to crack growth along an interface and in this investigation the toughness of an aluminum/epoxy interface was measured as a function of surface roughness and test temperature The large strain response of the relatively ductile epoxy adhesive used in this study was also characterized. This epoxy adhesive exhibits intrinsic strain-softening after initial compressive yield and then deforms plastically at a roughly constant flow stress until it rapidly hardens at large compressive strains. We find that interface toughness scales as the product of the temperature dependent epoxy yield strength and a length scale that characterizes surface roughness. The proposed scaling is based upon dimensional considerations of a model problem that assumes that the characteristic length scale of both the roughness and the crack-tip yield zone is small relative to the region dominated by the linear elastic asymptotic crack-tip stress field. Furthermore, the model assumes that interfacial failure occurs only after the epoxy begins to harden at large strains. The proposed relationship is validated by our interfacial toughness measurements.

International Journal of Fracture published new progress about Interface roughness. 22483-09-6 belongs to class alcohols-buliding-blocks, name is 2,2-Dimethoxyethanamine, and the molecular formula is C4H11NO2, COA of Formula: C4H11NO2.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts