Tag: M.W=100-150

Liao, Lieqiang published the artcileSupramolecular organogels fabricated with dicarboxylic acids and primary alkyl amines: controllable self-assembled structures, Related Products of alcohols-buliding-blocks, the main research area is supramol organogel dicarboxylic acid primary alkyl amine.

Supramol. organogels are soft materials comprised of low-mol.-mass organic gelators (LMOGs) and organic liquids Owning to their unique supramol. structures and potential applications, LMOGs have attracted wide attention from chemists and biochemists. A new “”superorganogel”” system based on dicarboxylic acids and primary alkyl amines (R-NH2) from the formation of organogels is achieved in various organic media including strong and weak polar solvents. The gelation properties of these gelators strongly rely on the mol. structure. Their aggregation morphol. in the as-obtained organogels can be controlled by the solvent polarity and the tail chain length of R-NH2. Interestingly, flower-like self-assemblies can be obtained in organic solvents with medium polarity, such as THF, pyridine and dichloromethane, when the gelators possess a suitable length of carbon chain. Moreover, further analyses of Fourier transformation IR spectroscopy and 1H NMR spectroscopy reveal that the intermol. acid-base interaction and van der Waals interaction are critical driving forces in the process of organogelation. In addition, this kind of organogel system displays excellent mech. properties and thermo-reversibility, and its forming mechanism is also proposed.

RSC Advances published new progress about Aggregation. 110-99-6 belongs to class alcohols-buliding-blocks, name is 2,2′-Oxydiacetic acid, and the molecular formula is C4H6O5, Related Products of alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Qin, Junhao published the artcileArsenic in leafy vegetable plants grown on mine water-contaminated soils: Uptake, human health risk and remedial effects of biochar, Recommanded Product: (S)-2-hydroxysuccinic acid, the main research area is arsenic vegetable health risk mine contaminated soil biochar remediation; Acidic mine water; Arsenic; Biochar; Human health risk; Leafy vegetable.

Field investigation and microcosm experiment were conducted to examine the uptake of arsenic by vegetable plants grown on the soils contaminated by acidic mine water and evaluate the human health risk from consuming the vegetables. Plant uptake of arsenic was related to the ratio of phosphorus to arsenic in soil solution for the same vegetable species. Bioaccumulation coefficient (BAC) of arsenic was highly variable amongst the different vegetable species with water spinach (white stem) and sweet potato leaf being identified as major vegetable species with high BAC. There was a reasonably good relationship between the gastric phase-bioaccessible arsenic and the gastrointestinal phase-bioaccessible arsenic. Consumption of the vegetables grown in the investigated area poses a significantly potential human health risk with a hazard quotient (HQ) of 2.7. Application of biochar significantly inhibited the uptake of arsenic by the vegetable plant due to protonation of biochar surfaces under acidic conditions, which favored adsorption of arsenic. The bioaccessibity of arsenic in the edible part of vegetable was also reduced due to biochar application. The HQ of the test vegetable plant (Gynura cusimbua) after soil amendment by biochar was reduced to 2 from 6 for the unamended soil.

Journal of Hazardous Materials published new progress about Allium cepa. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Recommanded Product: (S)-2-hydroxysuccinic acid.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Schreiber, Andreas published the artcilePrebiotic Protocell Model Based on Dynamic Protein Membranes Accommodating Anabolic Reactions, SDS of cas: 111-87-5, the main research area is prebiotic protocell model protein membrane anabolism evolution.

The nature of the first prebiotic compartments and their possible minimal mol. composition is of great importance in the origin of life scenarios. Current protocell model membranes are proposed to be lipid-based. This paradigm has several shortcomings such as limited membrane stability of monoacyl lipid-based membranes (e.g., fatty acids), missing pathways to synthesize protocell membrane components (e.g., phospholipids) under early earth conditions, and the requirement for different classes of mols. for the formation of compartments and the catalysis of reactions. Amino acids on the other hand are known to arise and persist with remarkable abundance under early earth conditions since the fundamental Miller-Urey experiments They were also postulated early to form protocellular structures, for example, proteinoid capsules. Here, we present a protocell model constituted by membranes assembled from amphiphilic proteins based on prebiotic amino acids. Self-assembled dynamic protein membrane-based compartments (PMBCs) are impressively stable and compatible with prevalent cellular membrane constituents forming protein-only or protein-lipid hybrid membranes. They can embed processes essential for extant living cells, such as enclosure of mols., membrane fusion, phase separation, and complex biosynthetic elements from modern cells demonstrating “”upward”” compatibility. Our findings suggest that prebiotic PMBCs represent a new type of protocell as a possible ancestor of current lipid-based cells. The presented prebiotic PMBC model can be used to design artificial cells, important for the study of structural, catalytic, and evolutionary pathways related to the emergence of life.

Langmuir published new progress about Amphiphiles. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, SDS of cas: 111-87-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wang, Jihong published the artcileSynthesis of an Oxidation-Sensitive Polyphosphoester Bearing Thioether Group for Triggered Drug Release, Related Products of alcohols-buliding-blocks, the main research area is polyphosphoester oxidation tumor antitumor photodynamic therapy photosensitizer paclitaxel.

In this work, novel amphiphilic diblock copolymers of polyethylene glycol and polyphosphoester with pendant thioether groups, denoted as mPEG-b-PMSPEP, were synthesized through the ring-opening polymerization of functionalized cyclic phosphoester monomer using methoxy poly(ethylene glycol) and Sn(Oct)2 as the macroinitiator and catalyst, resp. The successful synthesis was confirmed by 1H, 13C, 31P NMR and gel permeation chromatog. (GPC). These amphiphilic block copolymers self-assembled spontaneously in the aqueous solution, and the formed nanoparticles were sensitive to the oxidation that induced the hydrophobic to hydrophilic transition for its PMSPEP core under triggering of H2O2 and the subsequent dissociation of the nanoparticles. In addition, the reactive oxygen species (ROS) generated by light and the photosensitizer were also capable of carrying out the oxidation of these nanoparticles. Their oxidation profiles were systemically evaluated by 1H NMR. Finally, the mPEG-b-PMSPEP nanoparticles were used to coencapsulate the photosensitizer chlorin e6 (Ce6) and anticancer drug paclitaxel (PTX), achieving the photoaccelerated PTX release via oxidation of the nanoparticles by the generated ROS under light irradiation Meanwhile, the in vitro cytotoxicity assays indicated that these nanoparticles coencapsulated with PTX and Ce6 showed a combined cell-killing effect toward MDA-MB-231 tumor cells, exhibiting great potential for drug delivery systems that realize the synergistic chemo-photodynamic therapy for cancer treatment.

Biomacromolecules published new progress about Amphiphiles. 505-10-2 belongs to class alcohols-buliding-blocks, name is 3-(Methylthio)propan-1-ol, and the molecular formula is C4H10OS, Related Products of alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ouyang, Guanghui published the artcileSelf-assembly of chiral supra-amphiphiles, Related Products of alcohols-buliding-blocks, the main research area is review amphiphile self assembly chiral catalysis.

Supra-amphiphiles provide a brand-new powerful strategy for the construction of functional materials and have shown fascinating prospects in a variety of fields. When merged with chirality science, the concept of chiral supra-amphiphiles arises, which is an important subclass of supra-amphiphiles. In this review, we have provided a general introduction to the concept and design principle of chiral supra-amphiphiles as well as their self-assemblies. We have also highlighted some progress of chiral supra-amphiphiles in several application fields, such as chiroptical switches, chiral recognition, chiral catalysis and chiral luminescent soft materials. Although some elegant reviews have comprehensively looked back at the development and achievement of supra-amphiphiles, their research progress in chirality science has not been well summarized. We hope this review will provide useful guidance and understanding of self-assembly of chiral supra-amphiphiles, which we believe will benefit scientists in both colloidal chem. and chirality science.

Materials Chemistry Frontiers published new progress about Amphiphiles. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Related Products of alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Li, Shanlong published the artcileCoarse-Grained Model of Thiol-Epoxy-Based Alternating Copolymers in Explicit Solvents, Safety of n-Octanol, the main research area is coarse grained model thiol epoxy alternating copolymer explicit solvent.

The cosolvent method has been widely used in the self-assembly of amphiphilic alternating copolymers (ACPs), but the role of good and selective solvents is rarely investigated. Here, we have developed a coarse-grained (CG) model for the widely studied thiol-epoxy-based amphiphilic ACPs and a three-bead CG model for THF as the good solvent, which is compatible with the MARTINI water model. The accuracy of both the CG polymer and THF models was validated by reproducing the structural and thermodn. properties obtained from experiments or atomistic simulation results. D. in bulk, the radius of gyration, and solvation free energy in water or THF showed a good agreement between CG and atomistic models. The CG models were further employed to explore the self-assembly of ACPs in THF/water mixtures with different compositions Chain folding and liquid-liquid phase separation behaviors were found with increasing water fractions, which were the key steps of the self-assembly process. This work will provide a basic platform to explore the self-assembly of amphiphilic ACPs in solvent mixtures and to reveal the real role of different solvents in self-assembly.

Journal of Physical Chemistry B published new progress about Amphiphiles. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Safety of n-Octanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Song, Shaofei published the artcileCrystallization-Driven Self-Assembly of Amphiphilic Triblock Terpolymers With Two Corona-Forming Blocks of Distinct Hydrophilicities, Safety of n-Octanol, the main research area is self assembly amphiphilic triblock terpolymer polyferrocenyldimethylsilane methacrylate.

We report the synthesis and studies of self-assembly in solution of two related polyferrocenyldimethylsilane (PFS) ABC triblock terpolymers (TTPs), in which the BC blocks are amphiphilic comb diblock copolymers, PFS27-b-POEGMA180-b-PTDMA178 and PFS27-b-PTDMA181-b-POEGMA166. The subscripts refer to the mean ds.p. Crystallization-driven self-assembly of these TTPs was studied in four alc. solvents of decreasing polarity. Poly(tetradecyl methacrylate) (PTDMA) has limited solubility in 1-butanol below 45°C, whereas POEGMA exhibits upper critical solution temperature (UCST) behavior in 1-hexanol (27°C), 1-octanol (38°C), and 1-decanol (42°C). Consequently, the corona component below its UCST would be in a collapsed or microphase-separated state. PFS27-b-POEGMA180-b-PTDMA178 dissolved in hot 1-hexanol, 1-octanol, and 1-decanol and formed long rodlike micelles upon cooling. Micelle fragments generated by sonication served as seeds for both seeded growth and self-seeding experiments, leading to rodlike micelles of uniform length. PFS27-b-PTDMA181-b-POEGMA166 exhibited similar behavior in 1-butanol. The characteristic that these experiments have in common is that the outer block of the corona exhibits good solubility in the medium. PFS27-b-PTDMA181-b-POEGMA166 in the more hydrophobic alcs. behaved differently. Seeded growth experiments led to raftlike objects made up of 5-10 rodlike micelles of similar length, lined up side-by-side. The length of the rods, and hence the length of the rafts, increased linearly with the unimer-to-seed ratio. Self-seeding experiments with these micelle fragments, particularly in 1-octanol and 1-decanol, also led to raftlike objects built up from uniform rodlike micelle building block. We propose a model for raft formation based on the idea that at T < UCST for the outer POEGMA block, there is an attractive interaction between the corona blocks of the micelles. This attraction is strong enough to promote association but not strong enough to lead to precipitation Parallel alignment of the adjacent micelles of similar length maximizes the interaction between them. Macromolecules (Washington, DC, United States) published new progress about Amphiphiles. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Safety of n-Octanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Meklesh, Viktoriia published the artcileBending elastic modulus of a polymer-doped lyotropic lamellar phase, Related Products of alcohols-buliding-blocks, the main research area is bending elastic modulus polymer doped lyotropic lamellar phase; Adsorbing polymer; Deuterium NMR; Lyotropic lamellar phase; Mean bending elastic constant.

The effect of inserting a neutral water-soluble adsorbing polymer on the flexibility of amphiphilic bilayers in a lamellar phase is investigated. The Lα system is a stack of charged undulating bilayers composed of sodium dodecyl sulfate (SDS) and octanol separated by aqueous solutions of polyethylene glycol (PEG). The mean bending elastic modulus κ is determined from the quadrupole splittings in the solid state NMR spectra of the perdeuterated octanol chains embedded in the membranes that undergo collective fluctuations. Parameters for describing the membrane behavior (bilayer thickness, elastic compressibility modulus, order parameter) are obtained by supplementing the NMR data with complementary experiments (x-ray scattering), NMR spectral simulations, and theor. considerations. A fairly complete picture of the membrane rigidity emerges for any location in the lamellar phase thanks to a broad sweep of the lamellar domain by systematically varying the membrane fraction along dilution lines as well as the polymer composition The most remarkable result is the difference between dilute and semi-dilute regimes. In the dilute PEG solution, no (or slight pos. shift) polymer contribution to the rigidity curvature of the layered system is noted within the exptl. resolution ( â‰?0.3 kBT) and κ remains around 2.7 kBT. In contrast, the membrane rigidity increases steadily upon polymer addition once the crossover concentration cp* is exceeded, amounting to a 60% increase in κ at polymer concentration 2.5 cp* in the aqueous interlayers. These results are discussed with regard to the theor. expectation of membrane rigidification upon irreversible polymer adsorption.

Journal of Colloid and Interface Science published new progress about Amphiphiles. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Related Products of alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Manin, Alex N. published the artcileA combined experimental and theoretical study of nitrofuran antibiotics: crystal structures, DFT computations, sublimation and solution thermodynamics, Name: n-Octanol, the main research area is nitrofuran antibiotic crystal structure DFT computation sublimation solution thermodn; crystal lattice energy; crystal structure; furazolidone; nitrofurantoin; solubility; sublimation thermodynamics; transpiration method.

Single crystal of furazolidone (FZL) has been successfully obtained, and its crystal structure has been determined Common and distinctive features of furazolidone and nitrofurantoin (NFT) crystal packing have been discussed. Combined use of QTAIMC and Hirshfeld surface anal. allowed characterizing the non-covalent interactions in both crystals. Thermophys. characteristics and decomposition of NFT and FZL have been studied by differential scanning calorimetry (DSC), thermogravimetric anal. (TG) and mass-spectrometry. The saturated vapor pressures of the compounds have been measured using the transpiration method, and the standard thermodn. functions of sublimation were calculated It was revealed that the sublimation enthalpy and Gibbs energy of NFT are both higher than those for FZL, but a gain in the crystal lattice energy of NFT is leveled by an entropy increase. The solubility processes of the studied compounds in buffer solutions with pH 2.0, 7.4 and in 1-octanol was investigated at four temperatures from 298.15 to 313.15 K by the saturation shake-flask method. The thermodn. functions of the dissolution and solvation processes of the studied compounds have been calculated based on the exptl. data. Due to the fact that NFT is unstable in buffer solutions and undergoes a solution-mediated transformation from an anhydrate form to monohydrate in the solid state, the thermophys. characteristics and dissolution thermodn. of the monohydrate were also investigated. It was demonstrated that a combination of exptl. and theor. methods allows performing an in-depth study of the relationships between the mol. and crystal structure and pharmaceutically relevant properties of nitrofuran antibiotics.

Molecules published new progress about Antibiotics. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Name: n-Octanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kutzki, Olaf published the artcileSynthesis and properties of novel porphine-fullerene dyads for the investigation of light induced energy and electron transfer, Application In Synthesis of 50966-69-3, the main research area is fullerene porphyrin chlorin dyad preparation luminescence quenching; transition metal porphyrin chlorin fullerene preparation luminescence; copper pyrrolylpropyl deuteroporphyrin IX preparation; cobalt phosphonopropylporphyrin preparation; zinc porphyrin chlorin fullerene dyad preparation luminescence quenching.

A variety of dyads and more complex mol. arrangements of donor and acceptor subunits were designed to investigate light induced energy and electron transfer to mimic natural photosynthesis. Since the discovery and availability of the fullerenes, especially fullerene C60 was used as a subunit for the construction of mol. dyads which undergo light induced electron transfer from a porphinoid donor to the fullerene acceptor. A possible advantage of fullerenes over quinones, which were used as acceptors by nature and in the majority of artificial photosynthetic systems, is the ability of C60 to accept up to six electrons, and is the lower reorganization energy of C60 compared to quinones according to Marcus theory.

Proceedings – Electrochemical Society published new progress about Luminescence. 50966-69-3 belongs to class alcohols-buliding-blocks, name is 3-(1H-Pyrrol-1-yl)propan-1-ol, and the molecular formula is C7H11NO, Application In Synthesis of 50966-69-3.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts