Tag: M.W=100-150

Sidhu, Harmanpreet published the artcileRetention-release of ciprofloxacin and azithromycin in biosolids and biosolids-amended soils, Application In Synthesis of 111-87-5, the main research area is ciprofloxacin azithromycin biosolid amendment soil; Antibiotics; Batch equilibration; Bioaccessibility; Biosolids; DGT.

Ciprofloxacin (CIP) and azithromycin (AZ) are commonly prescribed antibiotics, often found at elevated concentrations in treated sewage sludge (biosolids), and could pose human and ecol. risks when land applied. Limited retention-release data preclude assessing potential risks from the target antibiotics in biosolids and biosolids-amended soils. The present work assessed sorption-desorption of CIP and AZ in biosolids and biosolids-amended soils using the “”traditional”” batch equilibration method. The batch equilibration method also included un-amended soils for comparison. Release potentials of the biosolids-borne antibiotics were assessed via multiple desorption equilibrations in the presence of CaCl2, soils, PbCl2, or competing antibiotic (CIP vs. AZ) solutions Desorption kinetics of CIP from biosolids were also evaluated by the diffusive gradient in thin films technique (DGT), coupled with a diffusion transport-exchange model available in 2D-DIFs. Sorption of both antibiotics followed linear models with partitioning coefficient (Kd) values for CIP ranging between 40 and 334 L kg-1 in soils and 357 L kg-1 in biosolids, and values for AZ ranging between 11 and 202 L kg-1 in soils and 428 L kg-1 in biosolids. Antibiotic desorption from the biosolids was highly hysteretic (hysteresis coefficients < 0.003) and desorption of the biosolids-borne chems. was extremely small (<3%) using any of the various desorption equilibration approaches. Desorption was hysteric in soils too; where desorption percentages were 4, 5, and 26% for CIP and 6, 32, and 50% for AZ in the silt loam soil, manured sand, and sand, resp. CIP release from biosolids determined by DGT was also small (<1%), ascribed to low dissolved and labile concentrations in the solid phase and a small effective diffusion coefficient Results obtained using equilibrium and dynamic approaches suggest that the target antibiotic bioaccessibilities from biosolids and finer-textured (typical agricultural) soils would be minimal and that biosolids (not soils) control desorption of the two biosolids-borne chems. Science of the Total Environment published new progress about Antibiotics. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Application In Synthesis of 111-87-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wei, Jianping published the artcileChemical composition, sensorial properties, and aroma-active compounds of ciders fermented with Hanseniaspora osmophila and Torulaspora quercuum in co- and sequential fermentations, Name: n-Octanol, the main research area is aroma compound fermented cider Hanseniaspora Torulaspora; 3-Methyl-1-butanol (PubChem CID: 31260); 3-Methylbutyl acetate (PubChem CID: 31276); Ethyl butanoate (PubChem CID: 7762); Ethyl hexanoate (PubChem CID: 31265); Ethyl octanoate (PubChem CID: 7799); Gas chromatography-olfactometry (GC-O); Glycerol (PubChem CID: 753); Hanseniaspora osmophila; Mixed fermentation; Partial least squares regression (PLSR); Phenylethyl alcohol (PubChem CID: 6054); Torulaspora quercuum; dl-malic acid (PubChem CID: 525); β-Damascenone (PubChem CID: 5366074); β-Phenethyl acetate (PubChem CID: 7654).

In this study, apple juice was fermented using Hanseniaspora osmophila X25-5 in pure culture as well as mixed culture with Torulaspora quercuum X24-4, which was inoculated simultaneously or sequentially. H. osmophila inhibited the growth of T. quercuum, while T. quercuum had little effect on the growth of H. osmophila. The simultaneous fermentation consumed relatively more sugar and resulted in the highest ethanol content. The production of organic acids varied depending on the yeast species employed and inoculation modality. Esters and alcs. were the main volatile families produced during fermentation, while Et esters and terpenes contributed most to the temperate fruity aroma. Gas chromatog.-olfactometry (GC-O) showed that 3-methyl-1-butanol, Et 2-methylbutanoate, phenylethyl alc., β-phenethyl acetate, and β-damascenone were the most potent odorants in all samples. This study suggested that simultaneous fermentation with H. osmophila and T. quercuum might represent a novel strategy for the future production of cider.

Food Chemistry published new progress about Apple juice. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Name: n-Octanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Shishov, Andrey published the artcileIn-syringe dispersive liquid-liquid microextraction using deep eutectic solvent as disperser: Determination of chromium (VI) in beverages, Application of n-Octanol, the main research area is syringe dispersive liquid microextraction deep eutectic solvent chromium beverage; Beverages; Chromium (VI); Deep eutectic solvent; Disperser solvent; Dispersive liquid-liquid microextraction; In-syringe flow system.

A novel approach for dispersive liquid-liquid microextraction based on the use of deep eutectic solvent as a disperser was presented for the first time. The procedure was automated based on an in-syringe flow system coupled with UV-Vis detection and demonstrated by the determination of chromium (VI) in beverages. This anal. task was used as a proof-of-concept example. The automated extraction procedure involved the aspiration of aqueous sample into a syringe pump with homogeneous mixture of extraction solvent (1-octanol) and deep eutectic solvent (tetrabutylammonium bromide – formic acid) containing color-forming reagent (1,5-diphenylcarbazide). This led to decomposition of deep eutectic solvent in aqueous phase resulting in dispersion of extraction solvent, oxidation of 1,5-diphenylcarbazide to 1,5- diphenylcarbazone in the presence of chromium (VI), and formation of colored chromium (III) complex with 1,5-diphenylcarbazone and its fast extraction In this case composition of deep eutectic solvent played a key role for analyte extraction Tetrabutylammonium bromide promoted mass transfer between aqueous phase and the extraction solvent droplets as a salting out agent, bromide ion acted as an ion-pare agent for analyte complex extraction, formic acid provided required pH value for analyte complex formation. Under the optimal conditions the limit of detection, calculated from a blank test based on 3s, was 0.2 μg L-1. The automated dispersive liquid-liquid microextraction using deep eutectic solvent as disperser can be considered as an available, efficient, rapid and environmentally friendly sample pretreatment approach.

Talanta published new progress about Apple juice. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Application of n-Octanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Medina, Sonia published the artcileDifferential volatile organic compounds signatures of apple juices from Madeira Island according to variety and geographical origin, Formula: C4H10OS, the main research area is apple juice volatile organic compound Portugal.

One of the main food authenticity issues is related to products�false labeling concerning their variety or geog. origin. For this reason, the aim of this study was to establish distinctive characteristics for the discrimination of apple juices according to regional varieties (Rijo, Verde, Ribeiro and Azedo) and geog. origin (Prazeres and Santo da Serra (Madeira Island)) on the basis of their volatile pattern by headspace solid-phase microextraction combined with gas chromatog. mass spectrometry (HS-SPME/GC-MS) combined with chemometric tools. The results obtained revealed a perfect discrimination between the different apple varieties, with Rijo apple juices as samples with the major relative concentration of ethanol, Et butanoate, Et 2-methylbutanoate and Et hexanoate. Moreover, this study allowed a geog. origin-based classification of Azedo apple juices, highlighting Et acetate, 2-methyl-1-propanol, Et hexanoate, and toluene (described for the first time in apple juices) as discriminatory features. This study demonstrated that volatile organic compounds (VOCs) could serve as authenticity indicators to verify variety and geog. origin of apple juices, providing local producers multiple benefits and legal protection against misuse of the products.

Microchemical Journal published new progress about Apple juice. 505-10-2 belongs to class alcohols-buliding-blocks, name is 3-(Methylthio)propan-1-ol, and the molecular formula is C4H10OS, Formula: C4H10OS.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Hao, Pengchao published the artcileAuxin-transporting ABC transporters are defined by a conserved D/E-P motif regulated by a prolylisomerase, Computed Properties of 97-67-6, the main research area is Arabidopsis ABCB1 mutation auxin proline malate prolylisomerase protoplast; ABC transporter; ABCB; FKBP; PPIase; Twisted Dwarf1; auxin; auxin transport; membrane transport; plant biochemistry; post-transcriptional regulation.

The plant hormone auxin must be transported throughout plants in a cell-to-cell manner to affect its various physiol. functions. ABCB transporters are critical for this polar auxin distribution, but the regulatory mechanisms controlling their function is not fully understood. The auxin transport activity of ABCB1 was suggested to be regulated by a phys. interaction with FKBP42/Twisted Dwarf1 (TWD1), a peptidylprolyl cistrans isomerase (PPIase), but all attempts to demonstrate such a PPIase activity byTWD1 have failed so far. By using a structurebased approach, we identified several surface-exposed proline residues in the nucleotide binding domain and linker of Arabidopsis ABCB1, mutations of which do not alter ABCB1 protein stability or location but do affect its transport activity. P1008 is part of a conserved signature D/E-P motif that seems to be specific for auxin-transporting ABCBs, which we now refer to as ATAs. Mutation of the acidic residue also abolishes auxin transport activity by ABCB1. All higher plant ABCBs for which auxin transport has been conclusively proven carry this conserved motif, underlining its predictive potential. Introduction of this D/E-P motif into malate importer, ABCB14, increases both its malate and its background auxin transport activity, suggesting that this motif has an impact on transport capacity. The D/EP1008 motif is also important for ABCB1-TWD1 interactions and activation of ABCB1-mediated auxin transport by TWD1. In summary, our data imply a new function for TWD1 acting as a putative activator of ABCB-mediated auxin transport by cistrans isomerization of peptidyl-prolyl bonds.

Journal of Biological Chemistry published new progress about Arabidopsis. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Computed Properties of 97-67-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Gondas, Eduard published the artcileExpression of pyruvate carboxylase in cultured human astrocytoma, glioblastoma and neuroblastoma cells, Computed Properties of 97-67-6, the main research area is pyruvatecarboxylase expression cultured astrocytoma glioblastoma neuroblastoma.

Pyruvate carboxylase (PC) is an enzyme catalyzing the conversion of pyruvate to oxaloacetate, which possesses anaplerotic role in cellular metabolism The expression of PC was confirmed in cells of several cancer types, in which it ensures several cellular functions, such as growth and division. To investigate the expression of PC in human astrocytoma, glioblastoma and neuroblastoma cells we applied the immunodetection methods. The results of the Western blot anal. and immunocytochem. detection revealed the presence of PC in human astrocytoma, glioblastoma and neuroblastoma cells. Furthermore, application of PC inhibitor, 3-chloro-1,2-dihydroxypropane (CDP), neg. impacts the viability of astrocytoma cells. The cytotoxic effect of CDP could be partially reversed by application of citrate, 2-oxoglutarate and malate in incubation media. Our results revealed that astrocytoma, glioblastoma and neuroblastoma cells are equipped with PC, which might significantly contribute by its anaplerotic activity to sustain the metabolism of cancer cells.

General Physiology and Biophysics published new progress about Astrocytoma. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Computed Properties of 97-67-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Cruz-Esteban, Samuel published the artcileThe attractant, but not the trap design, affects the capture of Drosophila suzukii in berry crops, Recommanded Product: 3-(Methylthio)propan-1-ol, the main research area is attractant drosophila suzukii strawberry raspberry blueberry; Color; monitoring; olfaction; spotted-wing drosophila; volatile compounds.

Drosophila suzukii (Matsumura) (Diptera: Drosophilidae) is recognized as an invasive pest in Europe and North America. In Mexico, it is one of the main insect pests of soft-skinned fruits such as blueberries, strawberries, raspberries, blackberries, plums, and guava. Previous studies have shown that D. suzukii uses visual and chem. cues during host plant searching. This knowledge has been used to develop traps and attractants for monitoring D. suzukii. In this study, five trap designs were evaluated to monitor D. suzukii under field conditions. Traps were baited with SuzukiiTrap, Z-Kinol, an attractant based on acetoin and methionol, or apple cider vinegar (ACV) enriched with 10% ethanol (EtOH) with the synergistic action of carbon dioxide (CO2). Our results suggested that the attractant was the determining factor in capturing D. suzukii, while trap design seemed to play a modest role. We found that traps baited with Z-Kinol captured the highest number of D. suzukii compared to that caught by traps baited with SuzukiiTrap, or ACV + EtOH + CO2. The highest catch numbers occurred in blackberry, followed by strawberry, raspberry, and blueberry. Traps captured more females than males. The results obtained may be useful for monitoring D. suzukii populations in Mexico and elsewhere, particularly in states where soft fruit crops are a component of agricultural activities.

Bulletin of Entomological Research published new progress about Attractants. 505-10-2 belongs to class alcohols-buliding-blocks, name is 3-(Methylthio)propan-1-ol, and the molecular formula is C4H10OS, Recommanded Product: 3-(Methylthio)propan-1-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Boyd, Anders published the artcileSerum tryptophan-derived quinolinate and indole-3-acetate are associated with carotid intima-media thickness and its evolution in hiv-infected treated adults, Application of (S)-2-hydroxysuccinic acid, the main research area is serum tryptophan quinolinate indole acetate carotid intima media thickness; HIV; antiretroviral; cardiovascular disease; carotid intima-media thickness; metabolomics; tryptophan metabolism.

Background. HIV-infected individuals undergoing effective antiretroviral therapy (ART) present an increased risk of atherosclerotic cardiovascular disease. We identified serum metabolites associated with carotid intima-media thickness (c-IMT) and its evolution. Methods. One hundred forty-three hydrophilic serum metabolites were measured by ultraperformance liquid chromatog. coupled with high-resolution mass spectrometry in 49 HIV+ ART+, 48 HIV+ ART-naive and 50 HIV-neg., age-matched, never-smoking male triads. Metabolites differentially altered between groups (“”features””) were defined as having a Benjamini-Hochberg-adjusted P value <.05 from a t test and >0.25 log2 absolute mean fold change in metabolite levels. c-IMT was measured across 12 sites at inclusion in all individuals and at the carotid artery (cca) after a median of 5.1 years in 32 HIV+ ART+ individuals. The difference in c-IMT (cross-sectional anal.) and slope of cca-IMT regression/progression per yr (longitudinal anal.) for each log10 (area) increase in metabolite level were estimated with linear regression. Results. Compared with HIV-, metabolite features of HIV+ ART+ were increased N6,N6,N6-trimethyl-L-lysine and decreased ferulate and 5-hydroxy-L-tryptophan, whereas features of HIV+ ART-naive were increased malate, kynurenine, 2-oxoglutarate, and indole-3-acetate and decreased succinate and 5-hydroxy-L-tryptophan. In HIV+ ART+ individuals, quinolinate and/or indole-3-acetate were pos. associated with c-IMT (P < .03), cca-IMT (P < .03), and cca-IMT progression (P < .008). These associations were not observed in HIV+ ART-naive or HIV-neg. individuals. In HIV+ ART+ individuals, the metabolites xanthosine and uridine, from nucleotide metabolism, and g-butyrobetaine, from lysine/dietary choline degradation, were also pos. or neg. associated with c-IMT and/or cca-IMT (all P < .01), but not its evolution. Conclusions. In these highly selected HIV-pos. ART-controlled males, 2 novel metabolites derived from tryptophan catabolism, indole-3-acetate and quinolinate, were associated with c-IMT and its progression. Open Forum Infectious Diseases published new progress about Blood serum. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Application of (S)-2-hydroxysuccinic acid.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Vazquez-Tato, M. Pilar published the artcileHighly Hydrophilic and Lipophilic Derivatives of Bile Salts, Computed Properties of 111-87-5, the main research area is bile salt hydrophilicity lipophilicity heat capacity partition coefficient; bile acids and salts; demicellization thermodynamics; hydrophilic-lipophilic balance; isothermal titration calorimetry; lipophilicity; partition coefficient.

Lipophilicity of 15 derivatives of sodium cholate, defined by the octan-1-ol/water partition coefficient (log P), has been theor. determined by the Virtual log P method. These derivatives bear highly hydrophobic or highly hydrophilic substituents at the C3 position of the steroid nucleus, being linked to it through an amide bond. The difference between the maximum value of log P and the min. one is enlarged to 3.5. The partition coefficient and the critical micelle concentration (cmc) are tightly related by a double-logarithm relationship (VirtuallogP=-(1.00 ±0.09)log(cmcmM)+(2.79±0.09)), meaning that the Gibbs free energies for the transfer of a bile anion from water to either a micelle or to octan-1-ol differ by a constant The equation also means that cmc can be used as a measurement of lipophilicity. The demicellization of the aggregates formed by three derivatives of sodium cholate bearing bulky hydrophobic substituents has been studied by surface tension and isothermal titration calorimetry. Aggregation numbers, enthalpies, free energies, entropies, and heat capacities, δCP,demic, were obtained. δCP,demic, being pos., means that the interior of the aggregates is hydrophobic.

International Journal of Molecular Sciences published new progress about Aggregation. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Computed Properties of 111-87-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Iakovleva, Ekaterina A. published the artcileAggregates of Ethoxylated Surfactant with Added n-Octanol: Details of Corona Structure from a Molecular-Thermodynamic Model, Product Details of C8H18O, the main research area is octanol ethoxylated surfactant aggregate corona structure thermodn model.

Polar heads of many nonionic surfactants have complex chem. structure. In the micellar aggregates these heads are engaged in specific and nonspecific interactions with one another and with the hydration water. We present here a mol.-thermodn. aggregation model that takes into account explicitly the hydrogen bonding and other specific interactions within the hydrated corona of a mixed nonionic aggregate. Apart from the aggregation characteristics that are usually obtained from the classical aggregation models – critical micelle concentration (CMC), the distribution of the aggregates over the size and shape and their composition – our model helps to establish a number of likely details of structure, including the corona thickness, hydration, and the partial penetration of the micelle components in the corona region. In this work the model is applied to describe the aggregation equilibrium in aqueous solutions of nonionic surfactants of the polyoxyethylene-p-(1,1,3,3-tetramethylbutyl)phenyl ether family that is closely related to Tritons, the com. surfactants of an extensive practical use. The model gives reasonable estimates of the CMCs and predicts correctly the trends in CMC and in the aggregation numbers vs the number of oxyethylene groups in the surfactant mol. The hydration numbers and the fraction of water engaged in hydrogen bonds are calculated For the hydration of the aggregate coronae, the predicted trend is in line with that found for other ethoxylated nonionic surfactants: poly(ethylene oxide) alkyl ethers and neonols. For surfactant solutions with added n-octanol, the model suggests that the tails of the octanol mols. are deeply buried in the cores of the mixed micelles with only one methylene group penetrating the coronae. We predict co-surfactant effect of added n-octanol: the depression of the CMCs is progressively stronger for more hydrophilic surfactants with larger EO heads.

Fluid Phase Equilibria published new progress about Aggregation. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Product Details of C8H18O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts