Tag: M.W=100-150

Li, Qianqian published the artcileExperimental and kinetic modeling study of laminar flame characteristics of higher mixed alcohols, Recommanded Product: n-Octanol, the main research area is higher mixed alc laminar flame kinetic model.

Mixturesof alcs.combining strengths of lower and higher alcs.show promising alternative properties as engine fuel. To aid the extensive application of the mixed alcs., detailed combustion investigation is necessary. In this study, laminar flame speeds and Markstein lengths were measured for simplified higher mixed alcs.(blends of methanol and n-hexanol/n-heptanol/n-octanol) with spherically propagating flame at 0.1 MPa, elevated temperatureof 433 K, and different mixing ratios. A comprehensive model was developed to describe the high temperaturechem.of the mixed alcs. The accuracy of the model was validated with present data. Results reveal that the three higher alcs.exhibited close laminar flame speeds and Markstein lengths resulting from their similar thermal, diffusion, and chem.kinetic properties. With the increasing mixing ratio of the higher alcs., the laminar flame speed decreased, especiallyfor the rich mixtures The maximum laminar flame speed slightly shifted to the lean side. The Markstein length increased at extremely lean mixturesand decreased at extremely rich mixtures, with the intersection occurring at the equivalence ratio between 1.2 and 1.3. The laminar flame speed variation of the mixed alcs.was dominated by chem. kinetics. Reaction pathway analyses indicated that the cracking process of each component in the mixed alcs.remains as that in the pure alcs. Such result demonstrated the chem.kinetic effect resulting from changes in fuel components.

Fuel Processing Technology published new progress about Combustion. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Recommanded Product: n-Octanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ruiz-Rodriguez, Irene published the artcileExperimental study of the effect of C8 oxygenates on sooting processes in high pressure spray flames, HPLC of Formula: 111-87-5, the main research area is oxygenate sooting spray flame combustion thermo phys chem property.

Oxygenated compounds have the ability to reduce soot emissions and to improve the combustion efficiency in engines. Most studies have focused on the soot reduction potential of shorter carbon chain oxygenates, while longer carbon chain oxygenates are still relatively unexplored. In this work, the soot reduction potential of long carbon chain oxygenates having similar thermo-phys. and chem. properties to those of diesel have been studied, viz., 2-octanone (ketone), 1-octanol (alc.), hexyl acetate (ester) and octanal (aldehyde). These oxygenates were injected at high pressure into a constant volume chamber maintained at high ambient temperature conditions, and their spray flames were investigated using a high-speed, two-color pyrometry system. It was found that for the same injected fuel mass, the oxygenates reduced the overall soot when compared to diesel. Small differences in sooting tendencies were observed between different oxygenated moieties but these were smaller than those relative to diesel. The absence of aromatic groups and the presence of oxygen directly bonded to carbon atoms seemed to have a larger effect on soot reduction than the oxygenated functional group. The oxygenates altered the local oxygen equivalence ratio in the spray, influencing the soot formation and its distribution in the flame. Under the high pressure conditions studied, the average sooting tendency of the long carbon-chain oxygenates studied increased in the order of: ester< aldehyde ∼ alc.HPLC of Formula: 111-87-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wang, Jinglan published the artcileEffect of diesel blended with di-n-butyl ether/1-octanol on combustion and emission in a heavy-duty diesel engine, Safety of n-Octanol, the main research area is butyl ether octanol diesel engine blend combustion emission; Butyl ether; Combustion; Diesel engine; Emission; Octanol.

Two kinds of C8 isomers, di-Bu ether (DNBE) and 1-octanol, as potential oxygen-containing alternative fuels, show important value in the trade-off between efficiency and emission. In the present work, the effects of DNBE/1-octanol with different proportions (0, 10%, and 20%) blended into diesel on the combustion characteristics, fuel economy, and emission characteristics in a six-cylinder heavy-duty diesel engine were studied at low, medium, and high loads. 1-Octanol with a 20% blending ratio showed different combustion characteristics in the cylinder compared with the other fuels. The economic anal. showed that the brake specific fuel consumption of DNBE-diesel blend fuels was higher than that of 1-octanol-diesel blend fuels, while brake thermal efficiency was the opposite tendency. The emissions of nitrogen oxides (NOx), hydrocarbons (HC), and carbon monoxide (CO) were affected by the types of blend fuels, blending ratios, and loads. In comparison with 1-octanol-diesel blend fuels, the addition of DNBE in diesel promoted the emission of nitrogen oxides, but inhibited the emissions of soot, HC, and CO. DNBE- and 1-octanol-diesel blend fuels increased the weighted brake specific fuel consumption but decreased the weighted brake thermal efficiency compared with diesel in the World Harmonized Stationary Cycle test cycle of Euro VI regulation. The weighted NOx, HC, soot, and CO emissions of blend fuels depended on the types of blend fuels and blend ratios. The weighted NOx, HC, and soot emissions were reduced by blending 1-octanol into diesel, while the weighted CO emission was increased. The weighted CO and soot emissions of diesel blended with DNBE were reduced than that of diesel.

Environmental Pollution (Oxford, United Kingdom) published new progress about Combustion. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Safety of n-Octanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Li, Xinglin published the artcileFacile synthesis of a 3D flower-like SiO2-MOF architecture with copper oxide as a copper source for enantioselective capture, Name: (S)-2-hydroxysuccinic acid, the main research area is copper maleate bipyridine silica supported preparation resolution enantiomer; phenyl methyl sulfoxide enantiomer separation silica supported copper oxide.

A facile self-template synthetic approach for the facile synthesis of a 3D flower-like SiO2-CuLBH architecture with copper oxide as a copper source has been demonstrated. The resulting composite as a sorbent showed a certain selective separation capability for Ph Me sulfoxide enantiomers (PMS) with an enantiomeric excess (ee) value of 31%.

New Journal of Chemistry published new progress about Composites. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Name: (S)-2-hydroxysuccinic acid.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Li, Lingzi published the artcileMetabolomics identifies a biomarker revealing in vivo loss of functional β-cell mass before diabetes onset, Recommanded Product: (S)-2-hydroxysuccinic acid, the main research area is diabetes beta cell mass metabolomics 1 5 anhydroglucitol liver.

Identification of individuals with decreased functional β-cell mass is essential for the prevention of diabetes. However, in vivo detection of early asymptomatic β-cell defect remains unsuccessful. Metabolomics has emerged as a powerful tool in providing readouts of early disease states before clin. manifestation. We aimed at identifying novel plasma biomarkers for loss of functional β-cell mass in the asymptomatic prediabetes stage. Nontargeted and targeted metabolomics were applied in both lean β-Phb2-/- (β-cell-specific prohibitin-2 knockout) mice and obese db/db (leptin receptor mutant) mice, two distinct mouse models requiring neither chem. nor dietary treatments to induce spontaneous decline of functional β-cell mass promoting progressive diabetes development. Nontargeted metabolomics on β-Phb2-/- mice identified 48 and 82 significantly affected metabolites in liver and plasma, resp. Machine learning anal. pointed to deoxyhexose sugars consistently reduced at the asymptomatic prediabetes stage, including in db/db mice, showing strong correlation with the gradual loss of β-cells. Further targeted metabolomics by gas chromatog.-mass spectrometry uncovered the identity of the deoxyhexose, with 1,5-anhydroglucitol displaying the most substantial changes. In conclusion, this study identified 1,5-anhydroglucitol as associated with the loss of functional β-cell mass and uncovered metabolic similarities between liver and plasma, providing insights into the systemic effects caused by early decline in β-cells.

Diabetes published new progress about Biomarkers. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Recommanded Product: (S)-2-hydroxysuccinic acid.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Mahoney, Lisa B. published the artcileMetabolomic profiling of extraesophageal reflux disease in children, Name: (S)-2-hydroxysuccinic acid, the main research area is extraesophageal reflux disease metabolite profile.

Although respiratory symptoms in children are often attributed to gastroesophageal reflux disease, establishing a clear diagnosis of extraesophageal reflux disease (EERD) can be challenging, as there are no sensitive or specific EERD biomarkers. The aim of this study was to evaluate the metabolite profile in bronchoalveolar (BAL) fluid from children with suspected EERD and assess the impact of reflux treatment on these metabolites. In this prospective pilot study, we performed nontargeted global metabolomic profiling on BAL fluid from 43 children undergoing testing with bronchoscopy, upper endoscopy, and multichannel intraluminal impedance with pH (pH-MII) for evaluation of chronic respiratory symptoms. Twenty-three (54%) patients had an abnormal pH-MII study. Seventeen (40%) patients were on proton pump inhibitors (PPIs) for testing. Levels of histamine, malate, AMP, and ascorbate were significantly lower in subjects with abnormal pH-MII studies compared to those normal studies. Furthermore, in children off PPI therapy, those with abnormal pH-MII studies had robust increases in a number of glycerophospholipids within phospholipid metabolic pathways, including derivatives of glycerophosphorylcholine, glycerophosphoglycerol, and glycerophosphoinositol, compared to those with normal pH-MII studies. These findings offer insight into the impact of reflux and PPIs on the lungs and provide a foundation for future studies using targeted metabolomic anal. to identify potential biomarkers of EERD.

Clinical and Translational Science published new progress about Biomarkers. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Name: (S)-2-hydroxysuccinic acid.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Golomb, Beatrice A. published the artcileA pilot study of bioenergetic marker relationships in gulf war illness: phosphocreatine recovery vs. citric acid cycle intermediates, Recommanded Product: (S)-2-hydroxysuccinic acid, the main research area is phosphocreatine alpha ketoglutarate biomarker Gulf War illness; 31-phosphorus magnetic resonance spectroscopy; Gulf War illness; bioenergetics; citric acid cycle; veterans.

Impaired bioenergetics have been reported in veterans with Gulf War illness (VGWIs), including prolonged post-exercise recovery of phosphocreatine (PCr-R) assessed with 31Phosphorus magnetic resonance spectroscopy. The citric acid cycle (CAC) is considered the most important metabolic pathway for supplying energy, with relationships among CAC markers reported to shift in some but not all impaired bioenergetic settings. We sought to assess relations of CAC markers to one another and to PCr-R. Participants were 33 VGWIs and 33 healthy controls 1:1 matched on age-sex-ethnicity. We assessed seven CAC intermediates, and evaluated PCr-R in a subset of matched case-control pairs (N = 14). CAC markers did not significantly differ between cases and controls. Relationships of alpha-ketoglutarate to malate, isocitrate, and succinate were strongly significant in cases with materially weaker relationships in controls, suggesting possible shifts in these markers in concert in VGWIs. PCr-R correlated strongly with five of seven CAC markers in controls (succinate, malate, fumarate, citrate, isocitrate, range r = -0.74 to -0.88), but bore no relationship in VGWIs. In summary, PCr-R related significantly to CAC markers in healthy controls, but not VGWIs. In contrast, relations of CAC markers to one another appeared to shift (often strengthen) in VGWIs.

International Journal of Environmental Research and Public Health published new progress about Biomarkers. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Recommanded Product: (S)-2-hydroxysuccinic acid.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Xiang, Xiao-le published the artcileNon-destructive characterization of egg odor and fertilization status by SPME/GC-MS coupled with electronic nose, Synthetic Route of 111-87-5, the main research area is egg odor fertilization volatile organic compound SPME electronic nose; SPME/GC-MS; electronic nose; fertile eggs; fertilized eggs; infertile eggs; odor; unfertilized eggs.

BACKGROUND : Early and non-destructive identification of fertile (F) eggs is a difficult task in the process of breeding laying hens. The odors emitted from unfertilized (UF), infertile (IF), and fertile (F) eggs were characterized by solid-phase microextraction / gas chromatograph-mass spectrometry (SPME/GC-MS) and electronic nose (E-nose) to determine their differences by principal component, partial least squares, and canonical discriminant analyses. RESULTS : A total of 14 volatiles were identified in unhatched shell white Leghorn eggs, such as nonanal, decanal, 6-methyl-5-hepten-2-one, and 6,10-dimethyl-5,9-undecadien-2-one. Cedrene and decanal contributed greatly to the classification of UF and fertilized (Fd)/IF eggs; cedrene, decanal, 1-octanol and hexanal contributed greatly to the distinction between UF and IF eggs; heptanal might be the potential marker to determine F/IF eggs. P40/1, P10/2, P10/1, TA/2, T40/2 and T30/1, P30/1, P40/2, PA/2, T40/2 mostly contributed to the distinction between UF and Fd eggs and between F and IF eggs, resp. Canonical discriminant anal. presented superior differentiating efficiency for almost all groups, and the odor differences between UF and Fd eggs were significantly larger than the differences between F and IF eggs. CONCLUSION : Solid-phase microextraction / gas chromatograph-mass spectrometer combined with E-nose may have the potential to non-destructively distinguish UF, F, and IF eggs, which will provide a new perspective to understand the differences among them. © 2018 Society of Chem. Industry.

Journal of the Science of Food and Agriculture published new progress about Biomarkers. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Synthetic Route of 111-87-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Branco, Renato Chaves Souto published the artcileProtein malnutrition mitigates the effects of a high-fat diet on glucose homeostasis in mice, Recommanded Product: (S)-2-hydroxysuccinic acid, the main research area is mouse glucose homeostasis HFD protein malnutrition; fat-enriched diet; gastrocnemius; insulin sensitivity; protein restriction.

Nutrient malnutrition, during the early stages of development, may facilitate the onset of metabolic diseases later in life. However, the consequences of nutritional insults, such as a high-fat diet (HFD) after protein restriction, are still controversial. We assessed overall glucose homeostasis and mol. markers of mitochondrial function in the gastrocnemius muscle of protein-restricted mice fed an HFD until early adulthood. Male C57BL/6 mice were fed a control (14% protein-control diet) or a protein-restricted (6% protein-restricted diet) diet for 6 wk. Afterward, mice received an HFD or not for 8 wk (mice fed a control diet and HFD [CH] and mice fed a protein-restricted diet and HFD [RH]). RH mice showed lower weight gain and fat accumulation and did not show an increase in fasting plasma glucose and insulin levels compared with CH mice. RH mice showed higher energy expenditure, increased citrate synthase, peroxisome-proliferator-activated receptor gamma coactivator 1-alpha protein content, and higher levels of malate and α-ketoglutarate compared with CH mice. Moreover, RH mice showed increased AMPc-dependent kinase and acetyl coenzyme-A (CoA) carboxylase phosphorylation, lower i.m. triacylglycerol content, and similar malonyl-CoA levels. In conclusion, protein undernourishment after weaning does not potentiate fat accumulation and insulin resistance in adult young mice fed an HFD. This outcome seems to be associated with increased skeletal muscle mitochondrial oxidative capacity and reduced lipids accumulation.

Journal of Cellular Physiology published new progress about Biomarkers. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Recommanded Product: (S)-2-hydroxysuccinic acid.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chavez-Marquez, Alejandra published the artcileCharacterization of Cabernet Sauvignon Wines by Untargeted HS-SPME GC-QTOF-MS, Application In Synthesis of 505-10-2, the main research area is furfuryl ethyl ether acetoin acetic acid alpha terpineol metabolomics; HS-SPME GC-QTOFMS; Mexican wine; metabolomics; untargeted method validation; wine.

Untargeted metabolomics approaches are emerging as powerful tools for the quality evaluation and authenticity of food and beverages and have been applied to wine science. However, most fail to report the method validation, quality assurance and/or quality control applied, as well as the assessment through the metabolomics-methodol. pipeline. Knowledge of Mexican viticulture, enol. and wine science remains scarce, thus untargeted metabolomics approaches arise as a suitable tool. The aim of this study is to validate an untargeted HS-SPME-GC-qTOF/MS method, with attention to data processing to characterize Cabernet Sauvignon wines from two vineyards and two vintages. Validation parameters for targeted methods are applied in conjunction with the development of a recursive anal. of data. The combination of some parameters for targeted studies (repeatability and reproducibility < 20% RSD; linearity > 0.99; retention-time reproducibility < 0.5% RSD; match-identification factor < 2.0% RSD) with recursive anal. of data (101 entities detected) warrants that both chromatog. and spectrometry-processing data were under control and provided high-quality results, which in turn differentiate wine samples according to site and vintage. It also shows potential biomarkers that can be identified. This is a step forward in the pursuit of Mexican wine characterization that could be used as an authentication tool. Molecules published new progress about Biomarkers. 505-10-2 belongs to class alcohols-buliding-blocks, name is 3-(Methylthio)propan-1-ol, and the molecular formula is C4H10OS, Application In Synthesis of 505-10-2.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts