Tag: 200-300

Synthesis of magnetic nanocomposites and sensitive detection for copper (II) was written by Jiao, Yuan;Liu, Fuyong;Wang, Songbai;Shuang, Shaomin;Dong, Chuan. And the article was included in Yingyong Huaxue in 2017.Recommanded Product: 65-22-5 The following contents are mentioned in the article:

The magnetic nanoparticles (NPs) coated with silica NPs (Fe₃O₄@SiO₂) were prepared by chem. co-precipitation method. A multifunctional magnetic nanocomposite (Fe₃O₄@SiO₂-Pyh) was fabricated by grafting pyridoxal hydrazide (Pyh) to the surface of Fe₃O₄@SiO₂ NPs via hexamethylene diisocyanate. The structure, morphol., and magnetic property of Fe₃O₄@SiO₂-Pyh were characterized by Fourier transform IR spectroscopy, transmission electron microscopy, and X-ray powder diffraction. The Fe₃O₄@SiO₂-Pyh has a clear core shell architecture, in which an average particle diameter is 50-55 nm with about 15 nm SiO₂ shell. Fe₃O₄@SiO₂-Pyh contains -CO-NH-N=CH- active groups, which can coordinate with Cu²⁺ to form stable complex. Based on this principle we established an anal. method for the determination of Cu²⁺, which was characterized by UV-Vis spectroscopy. The linear range of detecting Cu²⁺ concentration is 3.4 × 10^-7-4.5 × 10^-6 mol/L with detection limit 1.03 × 10^-7 mol/L. Moreover, the nanocomposites display superparamagnetic properties, which can be used for effective separation of excess Cu²⁺ from the liquid phase by applying an external magnetic field. As-synthesized Fe₃O₄@SiO₂-Pyh can be a good candidate for selective detection and simple removal of Cu²⁺ in environmental fields. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Recommanded Product: 65-22-5).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Recommanded Product: 65-22-5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Peanut shells-derived biochars as adsorbents for the pipette-tip solid-phase extraction of endocrine-disrupting phenols in water, milk and beverage was written by Sun, Ruiting;Lu, Fuwei;Yu, Chunmei;Yang, Yanan;Qiao, Lizhen;Liu, Anmin. And the article was included in Journal of Chromatography A in 2022.Recommanded Product: 620-92-8 The following contents are mentioned in the article:

In the present work, a type of biochar materials derived from carbonizing peanut shells were obtained and employed as the adsorbents of pipet-tip solid-phase extraction (PT-SPE) for the enrichment and determination of six endocrine-disrupting phenols (EDPs) in combination with high-performance liquid chromatog. equipped with UV detector (HPLC-UV). Abundant aliphatic and aromatic carbon structures and functional groups from polar heteroatoms (N, O, S) were distributed in the low-cost and eco-friendly peanut shells-derived biochar materials and were favorable for the enrichment of target EDPs. Moreover, the theor. calculation based on d. functional theory (DFT) proved that the effective enrichment of EDPs in aqueous samples benefited from the effective adsorption on the peanut shells-derived biochar materials. The exptl. factors influencing the extraction efficiency were investigated, including adsorbent amount, aspirating/dispensing cycles, the type of elution solvent and elution times, salt addition, sample solution pH and type and volume of washing solvent. Under the optimal conditions, the proposed PT-SPE method exhibited good linear relationship (R2 > 0.993) in the range of 0.5-400μg/L and low limits of detections (LODs) from 0.25 to 2.5μg/L, as well as good precision and accuracy with relative standard deviations (RSDs) of 0.3%-13.2% and recoveries of 83.5%-117.1%. Finally, the biochars-based miniaturized pretreatment method was employed for the determination of six EDPs in bottled water, milk, tea beverage and disposal plastic bag soaked solution with recoveries from 77.5% to 116.5%. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Recommanded Product: 620-92-8).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Recommanded Product: 620-92-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Synthesis, X-ray structural features, DFT calculations and fluorescence studies of a new pyridoxal-benzimidazole ligand and its respective molybdenum complex was written by Pereira, Mateus Brum;Kopp, Cristieli R.;Fontana, Liniquer A.;Manzoni de Oliveira, Gelson;Back, Davi Fernando;Piquini, Paulo C.;Villetti, Marcos A.. And the article was included in New Journal of Chemistry in 2014.Electric Literature of C8H10ClNO3 The following contents are mentioned in the article:

Pyridoxal hydrochloride reacts with 1,2-phenylenediamine to give 4-(1H-benzimidazol-2-yl)-5-(hydroxymethyl)-2-methylpyridin-3-ol hydrochloride (BIMIPY, 1). The reaction of 1 with bis(acetylacetonato)-dioxidomolybdenum(VI) leads to the formation of the complex [(MoO₂)₂(H₂O)₂(μ-O)(BIMIPY-H⁺)₂]·4DMSO·2H₂O (2). In the binuclear complex the metal centers attain a distorted octahedral geometry; a water mol. coordinates to each Mo atom and two imidazolic ligands chelate two MoO₂⁺² ions. The sixth coordination position in complex 2 is accomplished by a μ-oxido ligand, with an inversion center, which connects two moieties of [(MoO₂)(H₂O)(BIMIPY-H⁺)] to a dinuclear species. Secondary, intermol. hydrogen bonds support the growth of the supramol. assembly of the Mo complex. Mechanisms for the formation of the functionalized benzimidazole ligand are also proposed and discussed. First principles DFT calculations of reactivity indexes are used to investigate a possible mechanism leading from the benzimidazole to a dimeric complex involving (MoO₂⁺²) mols. and an oxido bridge ligand. Further, the expected fluorescence of the complex is absent, due to decomposition of the complex in solution On the other hand, an exptl. investigation of the photophys. properties of the ligand shows that it is fluorescent. Time dependent d. functional theory calculations are performed to characterize the absorption and fluorescence spectra of the ligand. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Electric Literature of C8H10ClNO3).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Electric Literature of C8H10ClNO3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Metabolism and antioxidant activity of SlGSTD1 in Spodoptera litura as a detoxification enzyme to pyrethroids was written by Li, Dongzhi;Xu, Li;Liu, Hongyu;Chen, Xiling;Zhou, Lin. And the article was included in Scientific Reports in 2022.Synthetic Route of C9H18O5S The following contents are mentioned in the article:

Glutathione S-transferase (GSTs) are members of multifunction enzymes in organisms and mostly known for their roles in insecticide resistance by conjugation. Spodoptera litura (Fabricius) is a voracious agricultural pest widely distributed in the world with high resistance to various insecticides. The function of GSTs in the delta group of S. litura is still lacking. Significantly up-regulation of SlGSTd1 was reported in four pyrethroids-resistant populations and a chlorpyrifos-selected population. To further explore its role in pyrethroids and organophosphates resistance, the metabolism and peroxidase activity of SlGSTD1 were studied by heterologous expression, RNAi, and disk diffusion assay. The results showed that K_m and V_max for 1-chloro-2,4-dinitrobenzene (CDNB) conjugating activity of SlGSTD1were 1.68 ± 0.11 mmol L^-1 and 76.0 ± 2.7 nmol mg^-1 min^-1, resp. Cyhalothrin, beta-cypermethrin, and chlorpyrifos had an obvious inhibitory effect on SlGSTD1 activity, especially for fenvalerate, when using CDNB as substrate. Fenvalerate and cyhalothrin can be metabolized by SlGSTD1 in E. coli and in vitro. Also, silencing of SlGSTd1 significantly increased the toxicity of fenvalerate and cyhalothrin, but had no significant effect on the mortality of larvae treated by beta-cypermethrin or chlorpyrifos. SlGSTD1 possesses peroxidase activity using cumene hydroperoxide as a stress inducer. The comprehensive results indicate that SlGSTD1 is involved in fenvalerate and cyhalothrin resistance of S. litura by detoxication and antioxidant capacity. This study involved multiple reactions and reactants, such as (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol (cas: 367-93-1Synthetic Route of C9H18O5S).

(2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol (cas: 367-93-1) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Synthetic Route of C9H18O5S

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Bisphenol F suppresses insulin-stimulated glucose metabolism in adipocytes by inhibiting IRS-1/PI3K/AKT pathway was written by Chen, Huiling;Li, Jiangbin;Zhang, Yanchao;Zhang, Wei;Li, Xing;Tang, Huanwen;Liu, Yungang;Li, Tianlan;He, Haoqi;Du, Bohai;Li, Li;Shi, Ming. And the article was included in Ecotoxicology and Environmental Safety in 2022.Formula: C13H12O2 The following contents are mentioned in the article:

Obesity is one of the risk factors of metabolic diseases. Decreased sensitivity to insulin or impairment of the insulin signaling pathway may affect the metabolism of adipose tissue. Bisphenol F (BPF) has been widely used in various products as a substitute for bisphenol A (BPA). BPA has been defined as “obesogen”. However, knowledge about the correlation between BPF and obesity is very limited. This study was aimed to explore the effects of BPF on glucose metabolism and insulin sensitivity in mammalian tissues, using a mouse 3T3-L1 adipocyte line as the model. Differentiated 3T3-L1 adipocytes were treated with BPF at various concentrations for 24 h or 48 h, followed by the measurement of cell viability, lipid accumulation, expression levels of adipocytokines, glucose consumption, and impairment of the insulin signaling pathway. The results indicated that BPF had no effect on the size of 3T3-L1 adipocytes, but the expression of leptin, adiponectin and apelin was decreased, while that of chemerin and resistin was increased after 48 h of BPF treatment. Moreover, BPF inhibited the glucose consumption, the expression of GLUT4, and its translocation to the plasma membranes in 3T3-L1 adipocytes. Western blot anal. indicated that the activation of IRS-1/PI3K/AKT signaling pathway was inhibited by BPF, which resulted in reduced GLUT4 translocation. In conclusion, our data suggest that exposure of adipocytes to BPF may alter the expression of calorie metabolism-related adipokines and suppress insulin-stimulated glucose metabolism by impairing the insulin signaling (IRS-1/PI3K/AKT) pathway. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Formula: C13H12O2).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Formula: C13H12O2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Cytotoxicity and mutagenicity of particulate matter from the open burning of pruning wastes was written by Vicente, Estela D.;Figueiredo, Daniela;Goncalves, Catia;Vicente, Ana;Lopes, Isabel;Oliveira, Helena;Alves, Celia A.. And the article was included in Air Quality, Atmosphere & Health in 2022.Reference of 620-92-8 The following contents are mentioned in the article:

Burning vegetative debris is a worldwide long-standing practice. The current study was designed to examine the cytotoxicity and mutagenicity of particulate matter with an aerodynamic diameter below 10 μm (PM10) released from the burning of pruning residues common in Portugal and other countries of the Mediterranean region. Field measurements were conducted to collect PM10 samples from open burning of vines, olive, willow and acacia pruning branches. To assess the cytotoxicity of the PM10 total organic extract, the A549 cell line, representative of the alveolar type II pneumocytes of the human lung, was used. The cytotoxicity was checked using two complementary methods: water-soluble tetrazolium (WST-8) test to evaluate the cell metabolic activity and lactate dehydrogenase (LDH) activity assay to assess the loss of cell membrane integrity. The mutagenicity of the PM10-bound polycyclic aromatic hydrocarbons (PAHs) was screened through the Ames test. PM10 organic extracts induced LDH release in a dose-dependent manner. Regarding the cellular metabolic activity, dose-dependency was lacking for the majority of the samples. Combined WST-8 and LDH data indicate that PM10 exposure induce a necrotic cell death pathway in which the cell membrane integrity is lost. Direct and indirect mutagenicity towards the TA98 Salmonella strain has been recorded for the PAH extracts of PM10 collected from combustion of vine and willow branches during the ignition/flaming combustion stage. Significant correlations were found between the cytotoxic responses (WST-8 and LDH) and the PM10 organic component. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Reference of 620-92-8).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Reference of 620-92-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Synthesis, characterization, DFT calculations, protein binding and molecular docking studies of mononuclear dioxomolybdenum(VI) complexes with ONS donor ligand was written by Roy, Malini;Biswal, Debanjana;Sarkar, Oiendrilla;Pramanik, Nikhil Ranjan;Paul, Suvendu;Manna, Chandan Kumar;Mondal, Tapan Kumar;Chakrabarti, Syamal. And the article was included in Journal of Molecular Structure in 2021.Name: 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride The following contents are mentioned in the article:

Several new dioxomolybdenum(VI) complexes containing tridentate ONS donor ligand (H₂L) derived from pyridoxal and S-benzyldithiocarbazate have been synthesized by refluxing MoO₂(acac)₂ with Schiff base ligand and Lewis base (B) (where, B = pyridine, γ-picoline, 1-methylimidazole, tetrahydrofuran) in 1:1:1.5 M proportions in methanol. The complexes having general formula MoO₂LB (1–4) are thoroughly characterized by elemental analyses and various spectroscopic techniques (IR, ¹H NMR, UV-Vis and mass spectra). The structures of the complexes have been optimized by D. Functional Theory (DFT) calculations The hexa coordinated metal center possesses a distorted octahedral geometry in all the complexes. The redox behavior of the complexes is studied by cyclic voltammetry. The oxo-transfer reactivity of the MoO₂LB complexes with PPh₃ has also been examined The interactions of the complexes with Bovine Serum Albumin (BSA) protein are investigated spectroscopically by absorption, fluorescence titration and fluorescence life time measurements. The values of the Stern-Volmer constant (K_SV), binding constant (K_b) and number of binding sites (n) are determined which indicates significant binding with BSA protein. Fluorescence spectral change also indicates efficient FRET from the protein to ligand and complexes. Mol. docking studies have also been carried out to understand the binding modes and interaction patterns of the dioxomolybdenum(VI) complexes with BSA. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Name: 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Name: 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Artificial Consortium of three E. coli BL21 strains with synergistic functional modules for complete phenanthrene degradation was written by Zhang, Guangbao;Yang, Xiaohui;Zhao, Zhenhua;Xu, Tao;Jia, Xiaoqiang. And the article was included in ACS Synthetic Biology in 2022.Synthetic Route of C9H18O5S The following contents are mentioned in the article:

Polycyclic aromatic hydrocarbons (PAHs) are highly toxic and persistent organic pollutions that can accumulate in the environment. In this study, an aromatic ring cleavage module, a salicylic acid synthesis module, and a catechol metabolism module were resp. constructed in three Escherichia coli BL21 strains. Subsequently, the engineered strains were cocultured as an artificial consortium for the biodegradation of phenanthrene, a typical PHA. Single factor experiments and response surface methodol. were used to identify the optimal degradation conditions, including an inoculation interval of 6 h, inoculation ratio of 1:1:1, and IPTG concentration of 2 mM. Under these conditions, the 7-day degradation ratio of 100 mg/L phenanthrene reached 72.67%. Moreover, the engineered Escherichia coli BL21 strains showed good phenanthrene degradation ability at substrate concentrations 10 mg/L up to 500 mg/L. Enzyme activity assays combined with gas chromatog.-mass spectrometry measurements confirmed that the three engineered strains behaved as a synergistic consortium in the phenanthrene degradation process. Based on the anal. of the key metabolites, the engineered bacteria were supplemented at 7-day intervals in batches so that each engineered strain maintained its optimal degradation ability. The 21-day degradation ratio finally reached 90.66%, which was much higher than what was observed with simultaneous inoculation. These findings suggest that the three engineered strains with sep. modules constructed in this study offer an attractive solution for removing PAHs from the environment. This study involved multiple reactions and reactants, such as (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol (cas: 367-93-1Synthetic Route of C9H18O5S).

(2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol (cas: 367-93-1) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Synthetic Route of C9H18O5S

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Product specific thermal degradation kinetics of bisphenol F epoxy in inert and oxidative atmospheres using evolved gas analysis-mass spectrometry was written by Dwyer, Derek B.;Gallego, Nidia C.;Niedziela, Jennifer L.;Kapsimalis, Roger J.;Duckworth, Douglas C.. And the article was included in Journal of Analytical and Applied Pyrolysis in 2022.Reference of 620-92-8 The following contents are mentioned in the article:

Knowledge of the degradation kinetics for polymer materials is important for understanding thermal stability. Here, evolved gas anal.-mass spectrometry and pyrolysis gas-chromatog.-mass spectrometry were evaluated for the potential to deliver addnl. insight into thermal degradation kinetics of diglycidal ether of bisphenol F (DGEBF) epoxy thermoset under inert and oxidative atmospheres. Degradation products of selected precursor ions were evaluated for their uniqueness to the specific precursor using extracted ion thermographs. Unique mass peaks, solely attributed to a single reaction pathway of a specific product, were determined from extracted ion thermographs and used to determine both activation energy (E_a) and pre-exponential factors for the specific primary reaction pathways. These primary reaction pathways for DGEBF epoxy degradation were then evaluated in the context of transition state theory (TST) and related transition state enthalpies (ΔH‡) and entropies (ΔS‡) of activation to further elucidate the degradation process. It was determined under pyrolysis conditions, as suggested by the E_a, the formation of bisphenol F monomer was the rate-limiting step toward the formation of xanthene and phenol. In contrast, under thermo-oxidative conditions, reactions involving oxygen containing species were identified as the rate-limiting step for all observed products based on the large neg. ΔS‡ calculated from TST. This work demonstrates a powerful combination of technique and theory that can provide new insight into the degradation of polymer materials. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Reference of 620-92-8).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Reference of 620-92-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In utero exposure to bisphenols and asthma, wheeze, and lung function in school-age children: a prospective meta-analysis of 8 European birth cohorts was written by Abellan, Alicia;Mensink-Bout, Sara M.;Garcia-Esteban, Raquel;Beneito, Andrea;Chatzi, Leda;Duarte-Salles, Talita;Fernandez, Mariana F.;Garcia-Aymerich, Judith;Granum, Berit;Iniguez, Carmen;Jaddoe, Vincent W. V.;Kannan, Kurunthachalam;Lertxundi, Aitana;Lopez-Espinosa, Maria-Jose;Philippat, Claire;Sakhi, Amrit K.;Santos, Susana;Siroux, Valerie;Sunyer, Jordi;Trasande, Leonardo;Vafeiadi, Marina;Vela-Soria, Fernando;Yang, Tiffany C.;Zabaleta, Carlos;Vrijheid, Martine;Duijts, Liesbeth;Casas, Maribel. And the article was included in Environment International in 2022.Related Products of 620-92-8 The following contents are mentioned in the article:

In utero exposure to bisphenols, widely used in consumer products, may alter lung development and increase the risk of respiratory morbidity in the offspring. However, evidence is scarce and mostly focused on bisphenol A (BPA) only. To examine the associations of in utero exposure to BPA, bisphenol F (BPF), and bisphenol S (BPS) with asthma, wheeze, and lung function in school-age children, and whether these associations differ by sex. We included 3,007 mother-child pairs from eight European birth cohorts. Bisphenol concentrations were determined in maternal urine samples collected during pregnancy (1999-2010). Between 7 and 11 years of age, current asthma and wheeze were assessed from questionnaires and lung function by spirometry. Wheezing patterns were constructed from questionnaires from early to mid-childhood. We performed adjusted random-effects meta-anal. on individual participant data. Exposure to BPA was prevalent with 90% of maternal samples containing concentrations above detection limits. BPF and BPS were found in 27% and 49% of samples. In utero exposure to BPA was associated with higher odds of current asthma (OR = 1.13, 95% CI = 1.01, 1.27) and wheeze (OR = 1.14, 95% CI = 1.01, 1.30) (p-interaction sex = 0.01) among girls, but not with wheezing patterns nor lung function neither in overall nor among boys. We observed inconsistent associations of BPF and BPS with the respiratory outcomes assessed in overall and sex-stratified analyses. This study suggests that in utero BPA exposure may be associated with higher odds of asthma and wheeze among school-age girls. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Related Products of 620-92-8).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Related Products of 620-92-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts