Tag: 200-300

Controlling expression and inhibiting function of the toxin reporter for simple detection of the promoters’ activities in Escherichia coli was written by Chen, Yinghua;Li, Jinfeng;Zhang, Shuncheng;Hu, Jiong;Chen, Xiaofeng;Lin, Tingting;Dang, Dongya;Fan, Jun. And the article was included in Enzyme and Microbial Technology in 2022.Application In Synthesis of (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol The following contents are mentioned in the article:

The naturally occurring and mutated promoters inserted into expression plasmids or Escherichia coli chromosome are essential for recombinant protein production and metabolic engineering. Analyzing their activities and screening the promoter libraries require the simple and easy-to-use reporter. Here, we developed a novel and efficient approach to detect the promoter activity, based on E. coli cell growth inhibited by overexpression of bacteriophage ΦX174 gene E product (LyE), but recovered by pre-overexpression of Bacillus subtilis MraY (BsMraY). Under the conditional LyE construct expression in the absence or the presence of the BsMraY, activities of promoters including the reported P_T7/lac, P_tac, P_BAD, P_rha, P_hucR, P_prpB, P_cum, the wild type and engineered P_tet for leaky and induced expression, the P_thrC for auto-induction, and the P_ms for constitutive expression were assayed. In one-plasmid coexpression system, the PBAD promoter activity detected using the reporter gene was related to the insertion site. The constructed LyE toxic effects were correlated with toxin expression levels, as determined by the split green fluorescent protein reconstitution. Microscopic anal. showed that cells lysis occurred by the LyE induced with arabinose. Taken together, the toxin reporter construct is a convenient and cost-effective tool to examine the promoter activity in E. coli. This study involved multiple reactions and reactants, such as (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol (cas: 367-93-1Application In Synthesis of (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol).

(2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol (cas: 367-93-1) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Application In Synthesis of (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Associations of bisphenol exposure with the risk of gestational diabetes mellitus: a nested case-control study in Guangxi, China was written by Tang, Peng;Liang, Jun;Liao, Qian;Huang, Huishen;Guo, Xiaojing;Lin, Mengrui;Liu, Bihu;Wei, Bincai;Zeng, Xiaoyun;Liu, Shun;Huang, Dongping;Qiu, Xiaoqiang. And the article was included in Environmental Science and Pollution Research.Synthetic Route of C13H12O2 The following contents are mentioned in the article:

A growing number of epidemiol. studies have estimated the associations between endocrine-disrupting chems. and gestational diabetes mellitus (GDM). However, reports on the association between bisphenol A (BPA) substitutes and GDM are limited. This investigation aimed to explore the associations of maternal serum BPA, bisphenol B (BPB), bisphenol F (BPF), bisphenol S (BPS), and tetrabromobisphenol A (TBBPA) with the risk of GDM. A nested case-control study was performed among 500 pregnant women. In conditional logistic regression models, the OR for BPS was significantly increased in the medium exposure groups (OR = 1.77; 95% CI: 1.01, 3.13) compared with the reference group, while BPA (OR: 0.38, 95%CI: 0.29, 0.50) and TBBPA (OR: 0.67, 95%CI: 0.54, 0.85) were neg. associated with the risk of GDM. In the Bayesian kernel machine regression (BKMR) anal., the joint effect of bisphenols was pos. associated with the risk of GDM. BPS showed pos. relationship, while BPA and TBBPA showed neg. relationship, resp. The quantile g-computation revealed a statistically significant and neg. joint effect of the five bisphenols on the risk of GDM (OR: 0.57; 95% CI: 0.46, 0.72) with BPA (70.2%), TBBPA (21.3%), and BPB (8.5%) had pos. contribution to the overall effect. These findings suggested that BPS had a pos. effect on the risk of GDM, while BPA and TBBPA had neg. effect on the risk of GDM. Moreover, exposure to the mixture of the five bisphenols was neg. associated with the risk of GDM. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Synthetic Route of C13H12O2).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Synthetic Route of C13H12O2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Rapid and reagent-free bioassay using autobioluminescent yeasts to detect agonistic and antagonistic activities of bisphenols against rat androgen receptor and progesterone receptor was written by Huang, Yuan;Zhang, Wei;Zhang, Chengdong;Cui, Na;Xiao, Zhiming;Wang, Ruiguo;Su, Xiaoou. And the article was included in Journal of Steroid Biochemistry and Molecular Biology in 2022.Safety of 4,4′-Methylenediphenol The following contents are mentioned in the article:

Bisphenol A (BPA) and its analogs have been classified as endocrine disruptors via binding to nuclear receptors. Two novel bioassays, BLYrARS and BLYrPRS, were developed for rapid detection of agonistic and antagonistic activities of BPA and five of its analogs binding rat androgen receptor (rAR) and rat progesterone receptor (rPR). The reporter bioassay was based on two autonomously bioluminescent strains of the yeast Saccharomyces cerevisiae, recombined with a bacterial luciferase reporter gene cassette (lux) that can produce autofluorescence, regulated by the corresponding hormone response element acting as the responsive promoter. The bioluminescent signal is autonomous and continuous without cell lysis or addition of exogenous reagents. The AR agonist R1881 could be detected at 4 h with a half-maximal effective concentration (EC50) of ∼9.4 nM. The PR agonist progesterone could be determined at 4 h with an EC50 of ∼2.74 nM. None of the sixteen bisphenols presented agonistic activities against rAR and rPR. However, thirteen BPs were rAR antagonists and eleven BPs acted as rPR antagonists with different potency. The BLYrARS and BLYrPRS bioassay characterized by automated signal acquisition without addnl. manipulations or cost can be applied for simple and rapid detection of agonistic and antagonistic activities of BPs and other compounds acting as agonists or antagonists of rAR and rPR. Based on data derived by use of this bioassay endocrine-disrupting activities of some BPA analogs are more potent than BPA. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Safety of 4,4′-Methylenediphenol).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Safety of 4,4′-Methylenediphenol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Increasing ATP turnover boosts productivity of 2,3-butanediol synthesis in Escherichia coli was written by Boecker, Simon;Harder, Bjoern-Johannes;Kutscha, Regina;Pfluegl, Stefan;Klamt, Steffen. And the article was included in Microbial Cell Factories in 2021.Recommanded Product: (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol The following contents are mentioned in the article:

The alc. 2,3-butanediol (2,3-BDO) is an important chem. and an Escherichia coli producer strain was recently engineered for bio-based production of 2,3-BDO. However, further improvements are required for realistic applications. Here we report that enforced ATP wasting, implemented by overexpressing the genes of the ATP-hydrolyzing F1-part of the ATPase, leads to significant increases of yield and especially of productivity of 2,3-BDO synthesis in an E. coli producer strain under various cultivation conditions. We studied aerobic and microaerobic conditions as well as growth-coupled and growth-decoupled production scenarios. In all these cases, the specific substrate uptake and 2,3-BDO synthesis rate (up to sixfold and tenfold higher, resp.) were markedly improved in the ATPase strain compared to a control strain. However, aerobic conditions generally enable higher productivities only with reduced 2,3-BDO yields while high product yields under microaerobic conditions are accompanied with low productivities. Based on these findings we finally designed and validated a three-stage process for optimal conversion of glucose to 2,3-BDO, which enables a high productivity in combination with relatively high yield. The ATPase strain showed again superior performance and finished the process twice as fast as the control strain and with higher 2,3-BDO yield. Our results demonstrate the high potential of enforced ATP wasting as a generic metabolic engineering strategy and we expect more applications to come in the future. This study involved multiple reactions and reactants, such as (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol (cas: 367-93-1Recommanded Product: (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol).

(2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol (cas: 367-93-1) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Recommanded Product: (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Expression of the human molecular chaperone domain Bri2 BRICHOS on a gram per liter scale with an E. coli fed-batch culture was written by Schmuck, Benjamin;Chen, Gefei;Pelcman, Josef;Kronqvist, Nina;Rising, Anna;Johansson, Jan. And the article was included in Microbial Cell Factories in 2021.Formula: C9H18O5S The following contents are mentioned in the article:

The human Bri2 BRICHOS domain inhibits amyloid formation and toxicity and could be used as a therapeutic agent against amyloid diseases. For translation into clin. use, large quantities of correctly folded recombinant human (rh) Bri2 BRICHOS are required. To increase the expression and solubility levels of rh Bri2 BRICHOS it was fused to NT*, a solubility tag derived from the N-terminal domain of a spider silk protein, which significantly increases expression levels and solubility of target proteins. To increase the expression levels even further and reach the g/L range, which is a prerequisite for an economical production on an industrial scale, we developed a fed-batch expression protocol for Escherichia coli. A fed-batch production method for NT*-Bri2 BRICHOS was set up and systematically optimized. This gradual improvement resulted in expression levels of up to 18.8 g/L. Following expression, NT*-Bri2 BRICHOS was purified by chromatog. methods to a final yield of up to 6.5 g/L. After removal of the NT*-tag and separation into different oligomeric species, activity assays verified that different assembly states of the fed-batch produced rh Bri2 BRICHOS have the same ability to inhibit fibrillar and non-fibrillar protein aggregation as the reference protein isolated from shake flask cultures. The protocol developed in this work allows the production of large quantities of rh Bri2 BRICHOS using the solubility enhancing NT*-tag as a fusion partner, which is required to effectively conduct pre-clin. research. This study involved multiple reactions and reactants, such as (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol (cas: 367-93-1Formula: C9H18O5S).

(2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol (cas: 367-93-1) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Formula: C9H18O5S

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Quantum Chemical Calculation and Evaluation of Partition Coefficients for Classical and Emerging Environmentally Relevant Organic Compounds was written by Salthammer, Tunga;Grimme, Stefan;Stahn, Marcel;Hohm, Uwe;Palm, Wolf-Ulrich. And the article was included in Environmental Science & Technology in 2022.COA of Formula: C13H12O2 The following contents are mentioned in the article:

Octanol/water (K_OW), octanol/air (K_OA), and hexadecane/air (K_HdA) partition coefficients are calculated for 67 organic compounds of environmental concern using computational chem. The extended CRENSO workflow applied here includes the calculation of extensive conformer ensembles with semiempirical methods and refinement through d. functional theory, taking into account solvation models, especially COSMO-RS, and thermostatistical contributions. This approach is particularly advantageous for describing large and nonrigid mols. With regard to K_OW and K_HdA, one can refer to many exptl. data from direct and indirect measurement methods, and very good matches with results from our quantum chem. workflow are evident. In the case of the K_OA values, however, good matches are only obtained for the exptl. determined values. Larger systematic deviations between data computed here and available, nonexperimental quant. structure-activity relationship literature data occur in particular for phthalic acid esters and organophosphate esters. From a critical anal. of the coefficients calculated in this work and comparison with available literature data, we conclude that the presented quantum chem. composite approach is the most powerful so far for calculating reliable partition coefficients because all phys. contributions to the conformational free energy are considered and the structure ensembles for the two phases are generated independently and consistently. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8COA of Formula: C13H12O2).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.COA of Formula: C13H12O2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Comparing the effects of bisphenol A, C, and F on bovine theca cells in vitro was written by Tyner, Miles D. W.;Maloney, Madeline O.;Kelley, Brendan J. B.;Combelles, Catherine M. H.. And the article was included in Reproductive Toxicology in 2022.SDS of cas: 620-92-8 The following contents are mentioned in the article:

Endocrine disrupting chems. (EDCs) target aspects of hormone activity. Tightly coordinated crosstalk between two somatic cells of the ovary, granulosa and theca cells, governs steroid hormone production and plays a critical role in reproduction It is thus pertinent to understand the impact of EDCs on granulosa and theca cells. Bisphenol A (BPA), a well-known EDC, is widely used in the manufacturing of consumer products with humans routinely exposed. Strong evidence of the adverse effects of BPA on the female reproductive system has emerged and as a result, manufacturers have begun replacing BPA with other bisphenols, such as BPC and BPF. The safety of these analogs is currently unclear and should be investigated independently. Although much is known about the impact of BPA on granulosa cells, similar study of theca cells has been neglected. Further, there is a lack of studies on the impact of BPC and BPF on the female reproductive system. To fill these gaps, the present study compared the effect of BPA, BPC, and BPF on the viability and steroid production of theca cells from bovine, a clin. relevant model for human reproduction We show that BPC is more detrimental to theca cell viability and progesterone production compared to BPA. Surprisingly, we also found that BPF induces an increase in progesterone production compared to a decrease with BPA and BPC. To determine safety for the reproductive system, we conclude that a major shift away from BPA to bisphenol analogs should be investigated more thoroughly. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8SDS of cas: 620-92-8).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.SDS of cas: 620-92-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Novel nanohybrids for effervescence enhanced magnetic solid-phase microextraction of wide-polarity organic pollutants in roasted meat samples was written by Liu, Tingting;AgyeKum, Evans;Ma, Sai;Ye, Hanzhang;Li, Jiani;Gao, Ming;Ni, Min;Zhang, Xiaofan;Wang, Xuedong. And the article was included in Journal of Separation Science in 2021.Synthetic Route of C13H12O2 The following contents are mentioned in the article:

To simultaneously and efficiently extract pollutants with differential polarities, we herein fabricated and characterized a multifunctional nanocomposite. The novel nanohybrids used NiFe2O4 as magnetic cores, and NH2-MIL-101(Al), β-cyclodextrin and graphene oxide as functional components combined with magnetic cores. With the aid of graphene oxides large π-conjugated system, NH2-MIL-101(Al)s strong adsorption to moderately/strongly polar chems., and β-cyclodextrins specific recognition effect, the nanohybrids realized synergistically efficient extraction of polyaromatic hydrocarbons and bisphenols with a logKow range of 3-6. Combined with acidic and alk. sources, the nanohybrids-based effervescent tablets were prepared Based on effervescent reaction-enhanced nanohybrids-based efficient adsorption/extraction and high performance liquid chromatog. and fluorescence detection, we successfully developed an excellent microextraction method for the simultaneous determination of both polyaromatic hydrocarbons and bisphenols in roasted meat samples. Several important variables were optimized as follows: Na2CO3 and tartaric acid as acidic and alk. sources, 900μLof the mixed solvent (acetone and hexane at 2:1 by volume/volume) as the eluent, 5 min of elution time. Under optimized conditions, the novel method gave low limits of detection (0.07-0.30μg kg-1), satisfactory recoveries (86.9-103.9%), and high precision (relative standard deviations of 1.9-6.7%) in roasted lamb, beef, pork, chicken, and sausage samples. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Synthetic Route of C13H12O2).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Synthetic Route of C13H12O2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Transcriptome changes and potential immunotoxicity analysis in RAW264.7 macrophages caused by bisphenol F was written by Chen, Huiling;Zhang, Yanchao;Li, Xing;Zhang, Wei;He, Haoqi;Du, Bohai;Li, Tianlan;Tang, Huanwen;Liu, Yungang;Li, Li;Shi, Ming. And the article was included in Frontiers in Pharmacology in 2022.Formula: C13H12O2 The following contents are mentioned in the article:

As a viable substitute for bisphenol A (BPA), BPF has been widely used in the plastic industry and daily consumer goods, resulting in its detection in humans at a comparable concentration Evidence reveals that BPF and BPA may have similar toxic effects due to their similar structures. However, there is less information about BPF and its latent implications on the immune system, which is associated with many disorders. In this study, the in vitro toxicity of BPF on RAW264.7 macrophages was explored. The cells were treated with different concentrations of BPF (5, 10, 20, 50, 100, and 200 μM), the cell viability and apoptosis were detected, the gene expression profile was analyzed by wholetranscriptome sequencing, and the mRNA levels were detected by qRT-PCR. The results showed a high concentration of BPF could significantly reduce the survival rate of RAW264.7 macrophages. Although the medium concentration (20-50 μM) of BPF seemed to have no impact on the cell activity of macrophages, it caused the occurrence of apoptosis. The results of differential transcription showed that compared with the control group, 121 genes were upregulated and 82 genes were downregulated in the BPF group. The significantly changed gene functions were mainly concentrated in cell cycle, phagosome, lysosome, and antigen processing and presentation. These findings provide valuable information for correctly understanding the immunotoxicity risk of BPF and may help to improve the hazard identification of bisphenol compounds This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Formula: C13H12O2).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Formula: C13H12O2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Iron(III) and cobalt(III) complexes with pentadentate pyridoxal Schiff base ligand – structure, spectral, electrochemical, magnetic properties and DFT calculations was written by Muraskova, Viera;Eigner, Vaclav;Dusek, Michal;Sedmidubsky, David. And the article was included in Polyhedron in 2021.SDS of cas: 65-22-5 The following contents are mentioned in the article:

Three complexes, [FeLCl]Cl·H₂O, [Co₂L₂H₃O₂]Cl·4.8H₂O, and [CoLN₃], where L^2- is the dianion of an asym. propyl-Et pentadentate Schiff base ligand condensed from pyridoxal and N-(2-aminoethyl)propane-1,3-diamine, have been synthesized and characterized by elemental anal., FTIR and mass spectroscopy. Crystal structures of the complexes along with the Schiff base were determined by x-ray diffraction. ¹HNMR spectrum of the Schiff base has been obtained. The coordination polyhedra of all three complexes can be expressed as distorted octahedra. Magnetic investigations of [FeLCl]Cl·H₂O complex confirmed high-spin state over the whole temperature range (5-300 K) and allowed the evaluation of the axial zero-field splitting (ZFS) parameter D = -0.97 cm^-1, intermol. exchange parameter zj ́= -0.88 cm^-1 and temperature-independent paramagnetism χ_TIM = 0.00025 cm³mol^-1. The low-spin state of Co(III) was stabilized in diamagnetic [Co₂L₂H₃O₂]Cl·4.8H₂O and [CoLN₃] complexes. Redox potentials of the Schiff base and the complexes were investigated by cycling voltammetry on the GC electrode in dry acetonitrile. The exptl. magnetic properties of the complexes [FeLCl]Cl·H₂O and [CoLN₃] were compared with the theor. ones calculated using d. functional theory (DFT). This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5SDS of cas: 65-22-5).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.SDS of cas: 65-22-5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts