Tag: 200-300

Study of the degradation of epoxy resins used in spacecraft components by thermogravimetry and fast pyrolysis was written by Torres-Herrador, Francisco;Eschenbacher, Andreas;Blondeau, Julien;Magin, Thierry E.;Geem, Kevin M. Van. And the article was included in Journal of Analytical and Applied Pyrolysis in 2022.Synthetic Route of C13H12O2 The following contents are mentioned in the article:

Predicting the demisability upon re-entry of space debris objects is of great importance due to the threat these objects pose if they were to fall in an inhabited area. In particular, carbon/epoxy composite materials have been found on Earth in several occasions. Accurate models to assess the demisability of such components require, in particular, detailed thermal degradation data for the epoxy resin. In this work, we analyze a resin used to manufacture such components, using thermogravimetric anal. (TGA), organic elemental anal., and pyrolysis coupled to comprehensive two-dimensional gas chromatog. The epoxy resin rapidly decomposed in a relatively narrow range of temperatures (300-400 ^oC) in more than 70 different volatile products. A one-step kinetic model is proposed for the pyrolysis of epoxy based on thermogravimetry observations. The information on the species and elemental composition can be used to develop more accurate material degradation models for predicting the demisability upon re-entry of space debris. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Synthetic Route of C13H12O2).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Synthetic Route of C13H12O2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Removal of 18 bisphenols co-present in aqueous media by effectively immobilized titania photocatalyst was written by Zener, Bostjan;Matoh, Lev;Rodic, Peter;Skufca, David;Heath, Ester;Lavrencic Stangar, Urska. And the article was included in Journal of Environmental Chemical Engineering in 2021.Quality Control of 4,4′-Methylenediphenol The following contents are mentioned in the article:

In recent years, the increasing demand for clean and potable water has created a need for efficient, cost-effective wastewater treatment. One of the most promising methods is heterogeneous photocatalysis due to its ability to mineralize organic mols. This paper describes the development of a flow-through packed bed reactor system based on a packed column comprising glass beads coated with com. available TiO2 (P25). The resulting deposited films and corresponding powders were characterized using thermal anal. (TGA-DSC-MS), X-ray diffraction (XRD), scanning/transmission electron microscopy (SEM/TEM), sp. surface area (BET) and XPS measurements. The photocatalytic efficiency of the reactor was tested by observing the degradation rate of Plasmocorinth B, an organic dye, and 18 bisphenols co-dissolved in deionized water and simulated wastewater under UV light. The developed photocatalytic reactor effectively removed organic dye and bisphenols from the aqueous medium using a combination of adsorption and photocatalysis. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Quality Control of 4,4′-Methylenediphenol).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Quality Control of 4,4′-Methylenediphenol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Optimization of the Isopentenol Utilization Pathway for Isoprenoid Synthesis in Escherichia coli was written by Ma, Xiaoqiang;Liang, Hong;Pan, Qiuchi;Prather, Kristala L. J.;Sinskey, Anthony J.;Stephanopoulos, Gregory;Zhou, Kang. And the article was included in Journal of Agricultural and Food Chemistry in 2022.Recommanded Product: (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol The following contents are mentioned in the article:

Engineering microbes to produce isoprenoids can be limited by the competition between product formation and cell growth because biomass and isoprenoids are naturally derived from central metabolism Recently, a two-step synthetic pathway was developed to partially decouple isoprenoid formation from central carbon metabolism The pathway used exogenously added isopentenols as substrates. In the present study, we systematically optimized this isopentenol utilization pathway in Escherichia coli by comparing enzyme variants from different species, tuning enzyme expression levels, and using a two-stage process. Under the optimal conditions found in this study, ~300 mg/L lycopene was synthesized from 2 g/L isopentenol in 24 h. The strain could be easily modified to synthesize two other isoprenoid mols. efficiently (248 mg/L β-carotene or 364 mg/L R-(-)-linalool produced from 2 g/L isopentenol). This study lays a solid foundation for producing agri-food isoprenoids at high titer/productivity from cost-effective feedstocks. This study involved multiple reactions and reactants, such as (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol (cas: 367-93-1Recommanded Product: (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol).

(2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol (cas: 367-93-1) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Recommanded Product: (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Novel chelators based on adamantane-derived semicarbazones and hydrazones that target multiple hallmarks of Alzheimer’s disease was written by Palanimuthu, Duraippandi;Wu, Zhixuan;Jansson, Patric J.;Braidy, Nady;Bernhardt, Paul V.;Richardson, Des R.;Kalinowski, Danuta S.. And the article was included in Dalton Transactions in 2018.COA of Formula: C8H10ClNO3 The following contents are mentioned in the article:

Alzheimer’s disease (AD) is characterized by multiple pathol. hallmarks, including β-amyloid aggregation, oxidative stress, and metal dys-homeostasis. In the absence of treatments addressing its multi-factorial pathol., the authors designed novel multifunctional adamantane-based semicarbazones and hydrazones (1-12) targeting AD hallmarks. Of these, 2-pyridinecarboxaldehyde (N-adamantan-1-yl)benzoyl-4-amidohydrazone (10) was identified as the lead compound, which demonstrated: pronounced iron chelation efficacy; attenuation of Cu^II-mediated β-amyloid aggregation; low cytotoxicity; inhibition of oxidative stress; and favorable characteristics for effective blood-brain barrier permeation. Structure-activity relationships revealed that pyridine-derived hydrazones represent a promising pharmacophore for future design strategies due to their ability to bind critical Fe^II pools. Collectively, the unique multifunctional activity of these agents provides a novel therapeutic strategy for AD treatment. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5COA of Formula: C8H10ClNO3).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.COA of Formula: C8H10ClNO3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Insights into enhanced peroxydisulfate activation with S doped Fe@C catalyst for the rapid degradation of organic pollutants was written by Yu, Zhendong;Ma, Jiachen;Huang, Xiaoyi;Lv, Yuancai;Liu, Yifan;Lin, Chunxiang;Dou, Rongni;Ye, Xiaoxia;Shi, Yongqian;Liu, Minghua. And the article was included in Journal of Colloid and Interface Science in 2022.Quality Control of 4,4′-Methylenediphenol The following contents are mentioned in the article:

In this study, the S modified iron-based catalyst (S-Fe@C) for activating peroxydisulfate (PDS) was fabricated by heating the S-MIL-101 (Fe) precursor at 800°C. The resulted S-Fe@C composite mainly consisted of carbon, Fe⁰, FeS, FeS₂, and Fe₃O₄, and showed strong magnetism. Compared with Fe@C obtained from MIL-101 (Fe), the S-Fe@C exhibited much higher performance (1.5 times larger) on PDS activation and the S-Fe@C/PDS could rapidly degrade various organic pollutants in 5 min under the attack of the species of SO₄·^–, ¹O₂, electro-transfer and Fe(IV). The S element in enhancing the PDS activation mainly involved two mechanisms. Firstly, the doped S could speed up the electron transfer efficiency, resulting in a promotion on PDS decomposition; secondly, the S^2- S₂^2- or S⁰ could achieve the circulation of Fe²⁺ and Fe³⁺, leading to the formation of non-radicals Fe(IV) and ¹O₂. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Quality Control of 4,4′-Methylenediphenol).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Quality Control of 4,4′-Methylenediphenol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Efficient production of clerodane and ent-kaurane diterpenes through truncated artificial pathways in Escherichia coli was written by Li, Fang-Ru;Lin, Xiaoxu;Yang, Qian;Tan, Ning-Hua;Dong, Liao-Bin. And the article was included in Beilstein Journal of Organic Chemistry in 2022.Name: (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol The following contents are mentioned in the article:

The clerodane and ent-kaurane diterpenoids are two typical categories of diterpenoid natural products with complicated polycyclic carbon skeletons and significant pharmacol. activities. Despite exciting advances in organic chem., access to these skeletons is still highly challenging. Using synthetic biol. to engineer microbes provides an innovative alternative to bypass synthetic challenges. In this study, we constructed two truncated artificial pathways to efficiently produce terpentetriene and ent-kaurene, two representative clerodane and ent-kaurane diterpenes, in Escherichia coli. Both pathways depend on the exogenous addition of isoprenoid alc. to reinforce the supply of IPP and DMAPP via two sequential phosphorylation reactions. Optimization of these constructs provided terpentetriene and ent-kaurene titers of 66 ± 4 mg/L and 113 ± 7 mg/L, resp., in shake-flask fermentation The truncated pathways to overproduce clerodane and ent-kaurane skeletons outlined here may provide an attractive route to prepare other privileged diterpene scaffolds. This study involved multiple reactions and reactants, such as (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol (cas: 367-93-1Name: (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol).

(2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol (cas: 367-93-1) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Name: (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Effect of Starch Primers on the Fine Structure of Enzymatically Synthesized Glycogen-like Glucan was written by Liu, Jialin;Wang, Yanli;Li, Xiaoxiao;Jin, Zhengyu;Svensson, Birte;Bai, Yuxiang. And the article was included in Journal of Agricultural and Food Chemistry in 2022.Product Details of 367-93-1 The following contents are mentioned in the article:

Glycogen-like glucan (GnG) is a unique hyperbranched polysaccharide nanoparticle which is drawing increasing attention due to its biodegradability and abundant short branches that can be functionalized. Because starch and GnG are both composed of glucose residues and have similar glucosidic bonds, GnG could be fabricated by sucrose phosphorylase, α-glucan phosphorylase, and branching enzymes from starch primers and sucrose. In this study, high-amylose starch, normal starch, and waxy corn starch were used as primers to synthesize GnG, and their impact on the fine structure of GnG was investigated. Structural anal. indicated that with increasing content of amylopectin in the starch primer, the proportion of short chains in GnG decreased, and the degree of β-amylolysis and α-amylolysis was enhanced. Amylose in the primer contributed to a compact and homogeneous structure of GnG, while amylopectin triggered the formation of branch points with a more open distribution. These findings provide a new strategy for regulating the fine structure of GnG. This study involved multiple reactions and reactants, such as (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol (cas: 367-93-1Product Details of 367-93-1).

(2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol (cas: 367-93-1) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Product Details of 367-93-1

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Production and characterization of GPC3-N protein and its nanobody was written by Lao, Zhiting;Li, Shuanqi;Liang, Jinhui;Su, Jingyi;Gong, Xin;Cui, Xiping;Zhao, Suqing. And the article was included in Protein Expression and Purification in 2022.Related Products of 367-93-1 The following contents are mentioned in the article:

Glypican-3 (GPC3) has a promise to be the diagnostic biomarker as well as therapeutic target for hepatocellular carcinoma (HCC). Nanobody have the great potential in clin. diagnosis and treatment for their characteristics of small size, high solubility, stability, manipulability, binding advantages, and ease of production In this study, the recombinant glypican-3-N terminal (GPC3-N) protein was expressed as inclusion body in E. coli BL21(DE3)pLysS cells and then purified, which is then used as the immunogen to construct nanobody phage library. The pos. clone (named MF15) was obtained by four rounds of bio-panning, and then transformed into the E. coil TOP10F′ cells to express nanobody protein, with the mol. weight of 19 kDa. Both Western blot and immunofluorescence anal. revealed that bacterially expressed GPC3-N protein is biol. active, and MF15 could specifically recognized native GPC3 expressed in HepG2 cells. The results in this study would provide the tech. support for the development of diagnostic kits and antibody drugs targeting GPC3. This study involved multiple reactions and reactants, such as (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol (cas: 367-93-1Related Products of 367-93-1).

(2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol (cas: 367-93-1) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Related Products of 367-93-1

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Relationship between emergent BPA-substitutes and renal and cardiovascular diseases in adult population was written by Moreno-Gomez-Toledano, Rafael. And the article was included in Environmental Pollution (Oxford, United Kingdom) in 2022.COA of Formula: C13H12O2 The following contents are mentioned in the article:

Plastic waste pollution is one of the leading environmental problems of modern society. Its use, disposal, and recycling lead to the release of xenobiotic compounds such as bisphenol A (BPA), a known endocrine disruptor related to numerous pathologies. Due to the new restrictions on its use, it is gradually being replaced by derived mols., such as bisphenol F or S (BPF or BPS), whose health risks have not yet been adequately studied. In the present work, significant relationships between the new BPA substitute mols. and renal and cardiovascular diseases have been detected by performing binomial and multinomial logistic regressions in one of the worlds largest cohorts of urinary phenols. The results have shown a significant relationship between urinary BPF and renal function or heart disease (specifically congestive heart failure). Urinary BPS has shown a pos. relationship with the risk of hypertension and a neg. relationship with kidney disease. Consequently, applying new substitute mols. could imply potential health risks equivalent to BPA. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8COA of Formula: C13H12O2).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.COA of Formula: C13H12O2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Diaporthe/Phomopsis longicolla degrades an array of bisphenol analogues with secreted laccase was written by Baluyot, Jobriell C.;Santos, Hanna Keith;Batoctoy, Dessa Camille R.;Torreno, Vicenzo Paolo M.;Ghimire, Leela B.;Joson, Santiago Emil A. IV;Obusan, Marie Christine M.;Yu, Eizadora T.;Bela-ong, Dennis B.;Gerona, Roy R.;Velarde, Michael C.. And the article was included in Microbiological Research in 2022.Quality Control of 4,4′-Methylenediphenol The following contents are mentioned in the article:

With recent initiatives to ban bisphenol A (BPA) in certain com. products, manufacturers shifted to the production and use of BPA analogs. However, some of these BPA alternatives still possess endocrine disruptive activities. Many fungal enzymes are known to biodegrade phenolic compounds, such as BPA. However, the activity of these enzymes on BPA analogs remains unexplored. This study reports a secreted laccase from the endophytic fungus Diaporthe longicolla capable of degrading an impressive range of bisphenol analogs. The secreted crude enzymes are optimally active at pH 5 from 39°C to 60°C, efficiently degrading BPA as well as BPA analogs BPB, BPC, BPE and BPF. A purified form of laccase was identified from the crude fungal extract using FPLC and peptide sequencing. Furthermore, BPA induced the expression of this D. longicolla laccase gene. Overall, this paper demonstrated that the crude laccase enzyme from D. longicolla metabolizes BPA and select analogs, implicating the potential role of this fungus to remove environmental bisphenols. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Quality Control of 4,4′-Methylenediphenol).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Quality Control of 4,4′-Methylenediphenol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts