Tag: 200-300

Synthesis and Characterization of Poly(5′-hexyloxy-1′,4-biphenyl)-b-poly(2′,4′-bispropoxysulfonate-1′,4-biphenyl) with High Ion Exchange Capacity for Proton Exchange Membrane Fuel Cell Applications was written by Jin, Kunyu;Yue, Baohua;Yan, Liuming;Qiao, Risa;Zhao, Hongbin;Zhang, Jiujun. And the article was included in Chemistry – An Asian Journal in 2022.HPLC of Formula: 620-92-8 The following contents are mentioned in the article:

Proton exchange membrane (PEM) is pivotal for proton exchange membrane fuel cells (PEMFCs). In the present work, a block copolymer with hydrophilic alkyl sulfonated side groups and hydrophobic flexible alkyl ether side groups, poly(5′-hexyloxy-1′,4-biphenyl)-b-poly(2′,4′-bispropoxysulfonate-1′,4-biphenyl) (HBP-b-xBPSBP), is designed and synthesized by copolymerization of the hydrophilic and hydrophobic oligomers. The oligomers are synthesized via a Pd-catalyzed Suzuki cross-coupling of 1,3-dibromo-5-hexyloxybenzene, and 3,3′-[(4,6-dibromo-1,3-phenylene)bis(oxy)]bis(propane-1-sulfonate) or 1,4-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene. The good solubility and film-forming characteristics are achieved via the introduction of flexible hexyloxy side groups, and high ion exchange capacity (IEC) is achieved via the introduction of high d. of alkyl sulfonated side groups. The HBP-b-0.5BPSBP has the highest IEC of 3.17 mmol/g, the highest proton conductivity of 43.5 mS/cm at 95°C and 90% relative humidity (RH) and low methanol permeability of 6.45×10^-7 cm²/s. Meanwhile, crosslinked HBP-b-xBPSBP exhibits promising water uptake, swelling ratio and low methanol permeability. These characteristics are attributed to the crosslinked structure and the hydrophilic/hydrophobic nanophase separation morphol. promoted by the poly(m-phenylene) main chains, flexible alkyl ether groups, and alkyl sulfonated side groups. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8HPLC of Formula: 620-92-8).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.HPLC of Formula: 620-92-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Cu(II) complexes of a bio-compatible aminoguanidine Schiff base: Histidine sensing and DNA-binding studies was written by Chakraborty, Moumita;Mohanty, Monalisa;Dinda, Rupam;Sengupta, Swaraj;Kumar Chattopadhyay, Shyamal. And the article was included in Polyhedron in 2022.Application of 65-22-5 The following contents are mentioned in the article:

Two Cu(II) complexes of pyridoxal-aminoguanidine Schiff base ligand with formula [Cu(HL)Cl]₂(OAc)₂·4H₂O (1) and [Cu(HL)Cl(NCS)].H₂O (2) are reported. The ligand and the complexes were characterized by their elemental analyses, ESI-MS, Uv-Vis, IR spectroscopy and cyclic voltammetric measurements. Single crystal structures of complex 1 and 2 were solved by X-ray diffraction. In both the Cu(II) complexes Cu(II) ions are in a square pyramidal geometry having geometry index (τ) value of 0.11 for complex 1 and 0.15 for complex 2. Both the complexes bind to calf-thymus DNA with binding constant comparable to ethidium bromide. CD studies revealed an intercalative mode of binding for both the complexes. In addition, the complexes also show promising cleavage of pUC19 supercoiled plasmid DNA with 1 showing the highest cleavage activity of ∼ 99%. In addition, both the complexes selectively recognize L-histidine amino acid. The low detection limit values (0.085μM and 0.19μM for complexes 1 and 2, resp.) ascertain the making of an efficient L-histidine biosensor. The absorption, emission and mass spectral results establish the formation of Cu(His)₂ complex, with liberation of the fluorescent free ligand as the mechanism of sensing. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Application of 65-22-5).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Application of 65-22-5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Occurrence and risk assessment of organophosphate esters and bisphenols in San Francisco Bay, California, USA was written by Shimabuku, Ila;Chen, Da;Wu, Yan;Miller, Ezra;Sun, Jennifer;Sutton, Rebecca. And the article was included in Science of the Total Environment in 2022.COA of Formula: C13H12O2 The following contents are mentioned in the article:

Organophosphate esters and bisphenols are two classes of industrial chems. that are ubiquitously detected in environmental matrixes due to high global production and widespread use, particularly in the manufacture of plastic products. In 2017, water samples collected throughout the highly urbanized San Francisco Bay were analyzed for 22 OPEs and 16 bisphenols using liquid chromatog.-electrospray ionization-Q Trap-mass spectrometry. Fifteen of the 22 OPEs were detected, with highest median concentrations in the order TCPP (42 ng/L) > TPhP (9.5 ng/L) > TBOEP (7.6 ng/L) > TnBP (7.5 ng/L) > TEP (6.7 ng/L) > TDCIPP (6.2 ng/L). Pairwise correlation anal. revealed several strong, pos. correlations among OPEs, and few weak, neg. correlations between OPEs and BPA, suggesting differences between the two classes with respect to their sources, pathways, and/or fate in the environment. Concentrations of OPEs and bisphenols observed in this study were generally consistent with reported concentrations in other estuarine and marine settings globally. TDCIPP exceeded existing predicted no-effect concentrations at some sites, and six other compounds (TCrP, IDDPP, EHDPP, TPhP, TBOEP, and BPA) were observed at levels approaching individual compound PNECs (not considering mixture effects), indicating potential risks to Bay biota. Periodic monitoring can be used to maintain vigilance in the face of potential regrettable substitutions. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8COA of Formula: C13H12O2).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.COA of Formula: C13H12O2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Biosynthesis of L-5-methyltetrahydrofolate by genetically engineered Escherichia coli was written by Wang, Yubo;Zhang, Meng;Li, Lexin;Yi, Jihong;Liang, Jiyu;Wang, Shuning;Xu, Ping. And the article was included in Microbial Biotechnology.Application of 367-93-1 The following contents are mentioned in the article:

L-5-Methyltetrahydrofolate (L-5-MTHF) is the only biol. active form of folate in the human body. Production of L-5-MTHF by using microbes is an emerging consideration for green synthesis. However, microbes naturally produce only a small amount of L-5-MTHF. Here, Escherichia coli BL21(DE3) was engineered to increase the production of L-5-MTHF by overexpressing the intrinsic genes of dihydrofolate reductase and methylenetetrahydrofolate (methylene-THF) reductase, introducing the genes encoding formate-THF ligase, formyl-THF cyclohydrolase and methylene-THF dehydrogenase from the one-carbon metabolic pathway of Methylobacterium extorquens or Clostridium autoethanogenum and disrupting the gene of methionine synthase involved in the consumption and synthesis inhibition of the target product. Thus, upon its native pathway, an addnl. pathway for L-5-MTHF synthesis was developed in E. coli, which was further analyzed and confirmed by qRT-PCR, enzyme assays and metabolite determination After optimizing the conditions of induction time, temperature, cell d. and concentration of IPTG and supplementing exogenous substances (folic acid, sodium formate and glucose) to the culture, the highest yield of 527.84 μg g^-1 of dry cell weight for L-5-MTHF was obtained, which was about 11.8 folds of that of the original strain. This study paves the way for further metabolic engineering to improve the biosynthesis of L-5-MTHF in E. coli. This study involved multiple reactions and reactants, such as (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol (cas: 367-93-1Application of 367-93-1).

(2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol (cas: 367-93-1) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Application of 367-93-1

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

lon deletion impairs persister cell resuscitation in Escherichia coli was written by Mohiuddin, Sayed Golam;Massahi, Aslan;Orman, Mehmet A.. And the article was included in mBio in 2022.Recommanded Product: 367-93-1 The following contents are mentioned in the article:

Bacterial persisters are nongrowing cells highly tolerant to bactericidal antibiotics. However, this tolerance is reversible and not mediated by heritable genetic changes. Lon, an ATP-dependent protease, has repeatedly been shown to play a critical role in fluoroquinolone persistence in Escherichia coli. Although lon deletion (Δlon) is thought to eliminate persister cells via accumulation of the cell division inhibitor protein SulA, the exact mechanism underlying this phenomenon is not yet elucidated. Here, we show that Lon is an important regulatory protein for the resuscitation of the fluoroquinolone persisters in E. coli, and lon deletion impairs the ability of persister cells to form colonies during recovery through a sulA- and ftsZ-dependent mechanism. Notably, this observed “viable but nonculturable” state of antibiotic-tolerant Δlon cells is transient, as environmental conditions, such as starvation, can restore their culturability. Our data further indicate that starvation-induced SulA degradation or expression of Lon during recovery facilitates Z-ring formation in Δlon persisters, and Z-ring architecture is important for persister resuscitation in both wild-type and Δlon strains. Our in-depth image anal. clearly shows that the ratio of cell length to number of FtsZ rings for each intact ofloxacin-treated cell predicts the probability of resuscitation and, hence, can be used as a potential biomarker for persisters. This study involved multiple reactions and reactants, such as (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol (cas: 367-93-1Recommanded Product: 367-93-1).

(2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol (cas: 367-93-1) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Recommanded Product: 367-93-1

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Evaluation of curved root canals filled with a new bioceramic sealer: A microcomputed tomographic study using images with different voxel sizes and segmentation methods was written by Pinto, Jader Camilo;Torres, Fernanda Ferrari Esteves;Lucas-Oliveira, Everton;Bonagamba, Tito Jose;Guerreiro-Tanomaru, Juliane Maria;Tanomaru-Filho, Mario. And the article was included in Microscopy Research and Technique in 2021.Application In Synthesis of 4,4′-Methylenediphenol The following contents are mentioned in the article:

The aim of this study was to investigate the filling ability of a new premixed bioceramic sealer in comparison with an epoxy resin-based sealer in curved root canals using different segmentation methods and voxel sizes in micro-CT images. Twelve curved mesial roots of mandibular molars with two separated canals were selected. All root canals were prepared by using HyFlex EDM files size 25/.08 and filled by the single cone technique and Bio-C Sealer or AH Plus (n = 12). The samples were scanned by micro-CT at 5μm. The images were analyzed at 5, 10, and 20μm for the volumetric anal. of voids in filling. Visual image segmentation was performed by two examiners, and the automatic segmentation was accomplished for comparison. Radiopacity of the sealers was evaluated by radiog. anal. Data were submitted to the two-way ANOVA and non-paired t tests at a significance level of 5%. AH Plus had the highest radiopacity (p < .05). Root canals filled with AH Plus or Bio-C had similar low percentage of voids (p > .05). There was no difference interobserver, which had similar results to those obtained with automatic segmentation for all voxel sizes evaluated (p > .05). Bio-C Sealer had appropriate filling ability. Visual and automatic segmentation can be applied to micro-CT images with voxel sizes from 5 to 20μm to evaluate the filling of sealers with adequate radiopacity. Automatic segmentation should be used as a faster method. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Application In Synthesis of 4,4′-Methylenediphenol).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Application In Synthesis of 4,4′-Methylenediphenol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Design, synthesis and biological evaluation of novel thiosemicarbazone-indole derivatives targeting prostate cancer cells was written by He, Zhang-Xu;Huo, Jin-Ling;Gong, Yun-Peng;An, Qi;Zhang, Xin;Qiao, Hui;Yang, Fei-Fei;Zhang, Xin-Hui;Jiao, Le-Min;Liu, Hong-Min;Ma, Li-Ying;Zhao, Wen. And the article was included in European Journal of Medicinal Chemistry in 2021.Electric Literature of C8H10ClNO3 The following contents are mentioned in the article:

To discover novel anticancer agents with potent and low toxicity, a range of new thiosemicarbazone-indole analogs I [R = H, Me, Cl, OMe; R¹ = H, Me, R² = H, Me, OH, etc.; R³ = H, Me; X = N, C] based on lead compound II were designed and synthesized previously. Most compounds displayed moderate to high anticancer activities against five tested tumor cells (PC3, EC109, DU-145, MGC803, MCF-7). Specifically, the represented compound I [R = H, R¹ = Me; R² = Me, R³ = H] (III) possessed strong antiproliferative potency and high selectivity toward PC3 cells with the IC₅₀ value of 0.054μM, compared with normal WPMY-1 cells with the IC₅₀ value of 19.470μM. Preliminary mechanism research indicated that compound (III) could significantly suppress prostate cancer cells (PC3, DU-145) growth and colony formation in a dose-dependent manner. Besides, derivative (III) induced G1/S cycle arrest and apoptosis, which may be related to ROS accumulation due to the activation of MAPK signaling pathway. Furthermore, mol. (III) could effectively inhibit tumor growth through a xenograft model bearing PC3 cells and had no evident toxicity in vivo. Overall, based on the biol. activity evaluation, analog (III) can be viewed as a potential lead compound for further development of novel anti-prostate cancer drug. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Electric Literature of C8H10ClNO3).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Electric Literature of C8H10ClNO3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Peroxymonosulfate enhanced photocatalytic degradation of serial bisphenols by metal-free covalent organic frameworks under visible light irradiation: mechanisms, degradation pathway and DFT calculation was written by Liu, Fuyang;Dong, Qiqi;Nie, Chenyi;Li, Zhengmao;Zhang, Boaiqi;Han, Peng;Yang, Wulin;Tong, Meiping. And the article was included in Chemical Engineering Journal (Amsterdam, Netherlands) in 2022.Product Details of 620-92-8 The following contents are mentioned in the article:

Visible light driven peroxymonosulfate (PMS) activation by metal-free photocatalysts has attracted great attention. In present study, covalent organic frameworks (COF-PRD, PRD refers to pyridine) were synthesized and utilized to activate PMS to degrade bisphenol A (BPA) with visible light (VL) irradiation COF-PRD with PMS improved 3.5 times degradation kinetics for BPA degradation relative to that of COF-PRD without PMS with VL irradiation ·O₂^–, h⁺ and ¹O₂ dominated the BPA degradation in COF-PRD with PMS with VL irradiation Under anaerobic condition, BPA could still be effectively degraded due to the reaction of PMS with e^– to generate ·SO₄^–. In addition to BPA, bisphenol F (BPF), bisphenol B (BPB), bisphenol Z (BPZ) and bisphenol AP (BPAP) could also be effectively degraded by COF-PRD with PMS under VL irradiation conditions. D. functional theory (DFT) calculation together with intermediates determination showed that the main degradation pathway of bisphenols (BPs) included hydroxylation, electrophilic attack and ring-opening reaction. The bioaccumulation effects of BPs were greatly reduced during the degradation process. Moreover, COF-PRD exhibited excellent reusability in ten successive cycles. Clearly, COF-PRD could be employed as photocatalytic PMS activation to degrade bisphenols under both aerobic and anaerobic conditions. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Product Details of 620-92-8).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Product Details of 620-92-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Synthesis, characterization and antimicrobial activity of copper(II) complexes with hydrazone derived from 3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carbaldehyde was written by Mezey, Reka-Stefana;Mathe, Istvan;Shova, Sergiu;Grecu, Maria-Nicoleta;Rosu, Tudor. And the article was included in Polyhedron in 2015.Recommanded Product: 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride The following contents are mentioned in the article:

Pyridoxal isonicotinoyl hydrazone (HL) and its copper(II) complexes: [CuLCl(H₂O)₂] (1), [CuL(OAc)](H₂O) (2), [CuL(OAcac)] (3), [CuL(NO₃)](H₂O) (4), [CuL₂](H₂O) (5) were synthesized and characterized. The ligand was obtained by condensation of 3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carbaldehyde (pyridoxal) hydrochloride with isonicotinoyl hydrazide. The characterization of the formed compounds was done by ¹H NMR, ¹³C NMR, UV-visible, IR and EPR spectroscopy as well by thermal studies and elemental anal. The crystal structure of HL was determined by single crystal x-ray diffraction studies. The microbiol. effect of the ligand and all five complexes against both Gram-pos. and Gram-neg. strains, Staphylococcus aureus ATTC 6538, Bacillus cereus ATCC 14579, Escherichia coli W3110 and Pseudomonas aeruginosa ATCC 9027 was tested. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Recommanded Product: 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Recommanded Product: 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Genome-wide protein-DNA interaction site mapping in bacteria using a double-stranded DNA-specific cytosine deaminase was written by Gallagher, Larry A.;Velazquez, Elena;Peterson, S. Brook;Charity, James C.;Radey, Matthew C.;Gebhardt, Michael J.;Hsu, FoSheng;Shull, Lauren M.;Cutler, Kevin J.;Macareno, Keven;de Moraes, Marcos H.;Penewit, Kelsi M.;Kim, Jennifer;Andrade, Pia A.;LaFramboise, Thomas;Salipante, Stephen J.;Reniere, Michelle L.;de Lorenzo, Victor;Wiggins, Paul A.;Dove, Simon L.;Mougous, Joseph D.. And the article was included in Nature Microbiology in 2022.HPLC of Formula: 367-93-1 The following contents are mentioned in the article:

DNA-protein interactions are central to fundamental cellular processes, yet widely implemented technologies for measuring these interactions on a genome scale in bacteria are laborious and capture only a snapshot of binding events. We devised a facile method for mapping DNA-protein interaction sites in vivo using the double-stranded DNA-specific cytosine deaminase toxin DddA. In 3D-seq (DddA-sequencing), strains containing DddA fused to a DNA-binding protein of interest accumulate characteristic mutations in DNA sequence adjacent to sites occupied by the DNA-bound fusion protein. High-depth sequencing enables detection of sites of increased mutation frequency in these strains, yielding genome-wide maps of DNA-protein interaction sites. We validated 3D-seq for four transcription regulators in two bacterial species, Pseudomonas aeruginosa and Escherichia coli. We show that 3D-seq offers ease of implementation, the ability to record binding event signatures over time and the capacity for single-cell resolution This study involved multiple reactions and reactants, such as (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol (cas: 367-93-1HPLC of Formula: 367-93-1).

(2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol (cas: 367-93-1) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.HPLC of Formula: 367-93-1

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts