Tag: 200-300

MOF@COF functionalized cotton fiber as a platform for high performance extraction and removal of bisphenols from water samples was written by Xu, Xianliang;Zhang, Nan;Gao, Yan;Bao, Tao;Wang, Sicen. And the article was included in Journal of Environmental Chemical Engineering in 2022.Recommanded Product: 620-92-8 The following contents are mentioned in the article:

In the present work, a novel composite CCF@UiO-66-NH₂@TpBD (CCF stands for carboxyl cotton fiber) was fabricated for the extraction and removal of BPs from aqueous samples. Both the UiO-66-NH₂ (MOF) and TpBD (COF) were immobilized on CCF through feasible layer-by-layer and Schiff base reaction, and characterized using field emission SEM (FESEM) equipped with energy dispersive X-ray spectroscopy (EDS), X-ray diffraction (XRD), Fourier transform IR spectroscopy (FT-IR), and XPS techniques. The CCF@UiO-66-NH₂@TpBD was packed in pipet tip as micro-column to investigate the adsorption of BPs using a pipet tip solid-phase extraction (PT-SPE) method. Various parameters (sampling flow rate, sample pH, amount of adsorbent, ionic strength, methanol concentration, and flow rate of eluent) affecting the extraction efficiency were optimized. Based on strong π-π conjugation, hydrogen bonding, and hydrophobic interactions, the adsorbent exhibited good extraction and removal capability. A low limit of detection (0.16-0.75 ng/mL) and a high adsorption (4.3-5.6 mg/g) were obtained. Accordingly, the composite CCF@UiO-66-NH₂@TpBD material was shown to be a suitable adsorbent for the extraction and removal of BPs from aquatic samples due to excellent reusability, reproducibility, and high adsorption capacity. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Recommanded Product: 620-92-8).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Recommanded Product: 620-92-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Controlled and Predictably Selective Oxidation of Activated and Unactivated C(sp³)-H Bonds Catalyzed by a Molybdenum-Based Metallomicellar Catalyst in Water was written by Thiruvengetam, Prabaharan;Chand, Dillip Kumar. And the article was included in Journal of Organic Chemistry in 2022.Application of 620-92-8 The following contents are mentioned in the article:

The synthesis of carbonyl derivatives from renewable feedstocks, by direct oxidation/functionalization of activated and unactivated C(sp³)-H bonds under a controlled and predictably selective fashion, especially in late stages, remains a formidable challenge. Herein, for the first time, cost-effective and widely applicable protocols for controlled and predictably selective oxidation of petroleum waste and feedstock ingredients like methyl-/alkylarenes to corresponding value-added carbonyls have been developed, using a surfactant-based oxodiperoxo molybdenum catalyst in water. The methodologies use hydrogen peroxide (H₂O₂) as an environmentally benign green oxidant, and the reactions preclude the need of any external base, additive, or cocatalyst and can be operated under mild eco-friendly conditions. The developed protocols show a wide substrate scope and eminent functional group tolerance, especially oxidation-liable and reactive boronic acid groups. Upscaled multigram synthesis of complex steroid mols. by late-stage oxidation proves the robustness and practical utility of the current protocol since it employs an inexpensive recyclable catalyst and an easily available oxidant. A plausible mechanism has been proposed with the help of few controlled experiments and kinetic and computational studies. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Application of 620-92-8).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Application of 620-92-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Occurrence of bisphenols and benzophenone UV filters in wild brown mussels (Perna perna) from Algoa Bay in South Africa was written by Castro, Gabriela;Fourie, Amarein J.;Marlin, Danica;Venkatraman, Vishwesh;Gonzalez, Susana V.;Asimakopoulos, Alexandros G.. And the article was included in Science of the Total Environment in 2022.Category: alcohols-buliding-blocks The following contents are mentioned in the article:

Bisphenols and benzophenone UV filters are contaminants present in a wide variety of plastic materials and consumer products. The scientific attention towards these contaminants has increased in recent years due to their presence in microplastics, their ubiquitous occurrence in the environment, and their known endocrine disrupting health effects. In this study, the occurrence of nine bisphenol and five benzophenone UV-filter analogs was assessed in wild brown mussels (Perna perna) collected from different sampling sites along the coast of Algoa Bay, South Africa. Eleven out of fourteen target analytes were detected, and bisphenol AP (BPAP) was detected for the first time in mussels, presenting the highest median concentration of 150 ng g^-1 dry weight (d.w.) and a detection frequency of 91%. Regarding benzophenone UV-filters, median concentrations of the analogs (across all sites) ranged from 2.01 to 10.6 ng g^-1 d.w., with benzophenone-1 (BzP^-1) and benzophenone-3 (BzP-3) presenting the highest concentrations Human exposure was assessed by estimating daily intakes (EDI) of the target analytes through mussel consumption. To our knowledge, this is the first study from the African continent on the occurrence of bisphenols and benzophenone UV-filters in a large population (n=138) of wild brown mussels. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Category: alcohols-buliding-blocks).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Category: alcohols-buliding-blocks

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Computational risk assessment framework for the hazard analysis of bisphenols and quinone metabolites was written by Pandit, Shraddha;Singh, Prakrity;Parthasarathi, Ramakrishnan. And the article was included in Journal of Hazardous Materials in 2022.Application In Synthesis of 4,4′-Methylenediphenol The following contents are mentioned in the article:

Bisphenol A (BPA) is a widely used chem. in plastics but its proven harmful effects has led to the replacement and production of its analogs that might also induce hazard as well as associated risks. To elucidate the adverse impact of the BPA analogs, a comprehensive computational framework is developed which applies toxicogenomics aligned with D. Functional Theory (DFT) and Mol. Dynamics (MD) based approaches to understand the toxic potential of quinone metabolites of Bisphenol F (BPF) and 3,3′-dimethylbisphenol A (DMBPA). The obtained results indicate a similar chem. reactivity profile for these metabolites of bisphenols to BPA metabolite. MD simulation revealed that the quinone metabolites tend to interact with the DNA comprising hydrogen bonding, van der Waals forces, and electrostatic interactions as an onset for covalent binding to adduct formation. Structural anal. suggests that interactions with DC9, DG10, DG16, DA17, DA18, and DT19 play a crucial role in stabilizing the quinone metabolite in the interactive pocket of DNA. These observations are demonstrating that BPF and DMBPA have the potential to impose genotoxicity via forming the quinone metabolite adducts. Combination of DFT and MD-based computational approaches providing a structure-activity-toxicity spectrum of chems. can serve for the purpose of risk assessment. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Application In Synthesis of 4,4′-Methylenediphenol).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Application In Synthesis of 4,4′-Methylenediphenol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Dynamic changes in the chemical composition and metabolite profiles of drumstick (Moringa oleifera Lam.) leaf flour during fermentation was written by Shi, Honghui;Yang, Endian;Yang, Heyue;Huang, Xiaoling;Zheng, Mengxia;Chen, Xiaoyang;Zhang, Junjie. And the article was included in LWT–Food Science and Technology in 2022.Quality Control of (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol The following contents are mentioned in the article:

Solid-state fermentation (SSF) using mixed strains can increase the nutritional value and antioxidant content of Moringa oliefera Lam. leaf flour (MLF). However, little is known about the chem. composition and metabolite profiles of MLF during the fermentation process. In this work, mixed strains of Aspergillus Niger, Candida utilis and Bacillus subtilis were inoculated into MLF for SSF. The MLF′s contents of crude protein (CP), crude fiber (CF), water soluble carbohydrate (WSC), reducing sugar, tannin and phytic acid all changed significantly as fermentation proceeded. A metabolomic anal. was performed using GC-TOF-MS, resulting in the identification of 347 metabolites. Fermentation with mixed strains significantly affected levels of amino acids, sugars, and organic acids; concentrations of most amino acids, oligosaccharides, organic acids, nucleosides, γ-aminobutyric acid (GABA), and myo-inositol were higher after 3 d of SSF than at the start. Addnl., several intermediate metabolites were detected in 3 d fermented MLF. The mixed microorganisms′ metabolic activity thus seems to peak after 3 d of fermentation under the tested conditions. These results provide new insights into the changes in the chem. composition and metabolite content of MLF during SSF and reveal possibilities for producing valuable compounds via this process. This study involved multiple reactions and reactants, such as (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol (cas: 367-93-1Quality Control of (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol).

(2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol (cas: 367-93-1) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Quality Control of (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Multi-analyte gas chromatography-mass spectrometry method to monitor bisphenols, musk fragrances, ultraviolet filters, and pesticide residues in seafood was written by Petrarca, Mateus Henrique;Fernandes, Jose O.;Marmelo, Isa;Marques, Antonio;Cunha, Sara C.. And the article was included in Journal of Chromatography A in 2022.Category: alcohols-buliding-blocks The following contents are mentioned in the article:

A gas chromatog.-mass spectrometry method for the anal. of thirty-six anthropogenic contaminants in the edible portion of four distinct seafood items is reported. Considering the heterogeneous composition of algae, mussels, and lean/fatty fish muscles, a generic sample preparation based on the QuEChERS procedure combined with dispersive liquid-liquid microextraction (DLLME) with in situ acetylation was successfully applied for quantification of pesticide residues, bisphenols, musk fragrances and UV-filters. Matrix effects were influenced by the type of seafood, with the lowest effects being observed with EMR-lipid and graphitized carbon black sorbents in dispersive solid-phase extraction cleanup step. Method performance features were successful evaluated in the different seafood samples – algae, mussel, lean and fatty fish muscles, following the criteria established by SANTE/12682/2019 for anal. methods for pesticide residues anal. The detection and quantification of bisphenol F, musk fragrances (galaxolide and tonalide), UV-filters (2-ethylhexyl salicylate, 2-ethylhexyl 4-methoxycinnamate, and isoamyl 4-methoxycinnamate), and residues of permethrin in com. samples of algae, mussel and fish collected in a Portuguese estuary support the suitability of the proposed method for future seafood monitoring by food safety authorities. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Category: alcohols-buliding-blocks).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Category: alcohols-buliding-blocks

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

A flexible thermoelectric film based on Bi₂Te₂ for wearable applications was written by Liu, Changxin;Zhao, Kaiyuan;Fan, Yuhang;Gao, Yu;Zhou, Zhenghui;Li, Mengze;Gao, Yunfei;Han, Zhitao;Xu, Minyi;Pan, Xinxiang. And the article was included in Functional Materials Letters in 2022.Safety of 4,4′-Methylenediphenol The following contents are mentioned in the article:

In recent years, with the development of the Internet of Things (IoT) and wearable technol., the research and exploration of thermoelec. materials have been greatly promoted. However, traditional thermoelec. materials are rigid and brittle. Thermoelec. devices made of these materials usually cannot be closely attached to the heat and cold sources that provide temperature differences, thus limiting the application of thermoelec. materials. Therefore, manufacturing new high-performance flexible thermoelec. devices is still a huge challenge. In this work, polyimide/copper (PI/Cu) substrate was deposited by electron deposition technol. The flexible thermoelec. thin film device was fabricated by bonding N-type and P-type bismuth telluride (Bi₂Te₂) slurries onto the PI/Cu substrate. Then, the PDMS film was coated on the device to make the device waterproof and oxidation resistant. The output voltage and maximum power of this device, at the temperature of 80 K, reach 97.5 mV and 60 uW, resp. After 200 cycles of cyclic bending experiments, 90% high conductivity retention can be maintained. It demonstrates that the new flexible thermoelec. thin film has good flexibility and excellent stability. This work provides a simple method for the preparation of flexible thermoelec. thin films and opens up a new way for its application in the sensing equipment and wearable device of the IoT. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Safety of 4,4′-Methylenediphenol).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Safety of 4,4′-Methylenediphenol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Optimization of an ultrasound-assisted extraction method for the determination of parabens and bisphenol homologues in human saliva by liquid chromatography-tandem mass spectrometry was written by Moscoso-Ruiz, Inmaculada;Galvez-Ontiveros, Yolanda;Cantarero-Malagon, Samuel;Rivas, Ana;Zafra, Alberto. And the article was included in Microchemical Journal in 2022.Formula: C13H12O2 The following contents are mentioned in the article:

Parabens and bisphenols are endocrine disrupting chems. (EDCs) widely used in our daily lives. The main route of human exposure to these compounds is through the diet. This makes human saliva an important matrix for identification of these contaminants and evaluation of human exposure. In this work a multiresidue method to det the presence of methyl-, ethyl-, propyl-, isopropyl-, butyl- and isobutylparaben; and bisphenol A, B, C, E, F, M, P, S, Z, AP, AF and FL in human saliva samples has been developed. Sample treatment involves an initial step of protein pprotein in acidic medium and a second step of analyte extraction Extraction parameters were optimized using univariant and multivariant strategies. Microwave assisted extraction (MAE) and ultrasound assisted extraction (UAE) were compared and UAE was chosen the optimal extraction technique. The compounds were analyzed by ultra-high performance liquid chromatog. coupled to tandem mass spectrometry (UHPLC-MS/MS). The calibration in matrix was applied and the limits of detection and quantification were from 0.1 to 0.4 ng g-1 and from 0.3 to 1.0 ng g-1, respectivley. Accuracy was evaluated in terms of recovery (85.6 to 113.5%) with a relative standard deviation < 15% in all cases. The anal. method was successfully applied to quantify the target EDCs in ten human saliva samples, with some parabens being the most frequently detected compounds This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Formula: C13H12O2).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Formula: C13H12O2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Towards in situ continuous feeding via controlled release of complete nutrients for fed-batch culture of animal cells was written by Rawat, Jyoti;Gadgil, Mugdha. And the article was included in Biochemical Engineering Journal in 2020.Related Products of 65-22-5 The following contents are mentioned in the article:

Small-scale culture of animal cells in suspension is of importance for many applications. At a small-scale, fed-batch is achieved either by manual bolus feeding or the use of liquid handling robots. In this study, we report an alternate application of a hydrogel for in situ continuous delivery of a nutrient feed comprising 18 amino acids, vitamins, antioxidants, and trace elements. We show that amino acid release is sustained for at least seven days. Importantly, release rates of individual amino acids can be independently modulated by changing their loading. We demonstrate the application of this hydrogel for complete in situ feeding of nutrients to a suspension adapted CHO cell line expressing IgG leading to 2.7-fold and 4-fold improvement in integral viable cell d. (IVCD) and volumetric productivity resp. This is similar to improvements obtained by bolus liquid feeding. Further, supplying glucose from the same hydrogel to eliminate manual feeding led to a 1.8-fold increase in IVCD accompanied by a 3-fold increase in volumetric productivity as compared to batch culture. In summary, this study provides a proof-of-concept that hydrogels can enable completely closed in situ feeding for mammalian cell culture requiring no external intervention. Such continuous in situ delivery can potentially enable closed culture systems maintaining nutrients at low levels mimicking physiol. concentrations This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Related Products of 65-22-5).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Related Products of 65-22-5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Optimization of muscle cell culture media using nonlinear design of experiments was written by Cosenza, Zachary;Block, David E.;Baar, Keith. And the article was included in Biotechnology Journal in 2021.SDS of cas: 65-22-5 The following contents are mentioned in the article:

Optimizing media for biol. processes, such as those used in tissue engineering and cultivated meat production, is difficult due to the extensive experimentation required, number of media components, nonlinear and interactive responses, and the number of conflicting design objectives. Here we demonstrate the capacity of a nonlinear design-of-experiments (DOE) method to predict optimal media conditions in fewer experiments than a traditional DOE. The approach is based on a hybridization of a coordinate search for local optimization with dynamically adjusted search spaces and a global search method utilizing a truncated genetic algorithm using radial basis functions to store and model prior knowledge. Using this method, we were able to reduce the cost of muscle cell proliferation media while maintaining cell growth 48 h after seeding using 30 common components of typical com. growth medium in fewer experiments than a traditional DOE (70 vs. 103). While we clearly demonstrated that the exptl. optimization algorithm significantly outperforms conventional DOE, due to the choice of a 48 h growth assay weighted by medium cost as an objective function, these findings were limited to performance at a single passage, and did not generalize to growth over multiple passages. This underscores the importance of choosing objective functions that align well with process goals. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5SDS of cas: 65-22-5).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.SDS of cas: 65-22-5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts