Tag: 200-300

Discrimination of genetic and geographical groups of grape varieties (Vitis vinifera L.) based on their polyphenolic profiles was written by Sikuten, Iva;Stambuk, Petra;Tomaz, Ivana;Marchal, Cecile;Kontic, Jasminka Karoglan;Lacombe, Thierry;Maletic, Edi;Preiner, Darko. And the article was included in Journal of Food Composition and Analysis in 2021.Recommanded Product: 10083-24-6 This article mentions the following:

Relevant aspect of wine geog. origin is related to grapevine varieties used for wine production in specific wine country or region. The grapevine germplasm is highly variable and classified into geog. groups. These classifications were recently confirmed using genetic studies, and further classified varieties into geog.-genetic (GEN-GEO) groups. Polyphenolic compounds are important secondary metabolites in grapes and have an important impact on wine quality and sensory properties. The aim of this research was to investigate the polyphenolic profiles of 50 grape varieties from different GEN-GEO groups. The groups were C2 (varieties from Italy and France), C7 (varieties from Croatia), C8 (varieties from Spain and Portugal). Polyphenolic compounds analyzed belonged to the classes of anthocyanins, flavan-3-ols, flavonols, phenolic acids, and stilbenes. The most abundant classes of polyphenols were anthocyanins, followed by flavan-3-ols and flavonols. Using discriminant anal., the genetic-geog. groups were clearly separated based on their polyphenolic profiles, with all classes of compounds contributing to discrimination. In the experiment, the researchers used many compounds, for example, (E)-4-(3,5-Dihydroxystyryl)benzene-1,2-diol (cas: 10083-24-6Recommanded Product: 10083-24-6).

(E)-4-(3,5-Dihydroxystyryl)benzene-1,2-diol (cas: 10083-24-6) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Recommanded Product: 10083-24-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Tuning biodegradable hydrogel properties via synthesis procedure was written by Hawkins, Ashley M.;Tolbert, Melanie E.;Newton, Brittany;Milbrandt, Todd A.;Puleo, David A.;Hilt, J. Zach. And the article was included in Polymer in 2013.Safety of Diethyleneglycoldiacrylate This article mentions the following:

Biodegradable hydrogels have become a rapidly expanding area of research for biomedical applications. Poly(β-amino ester) (PBAE) biodegradable hydrogels, in particular, have been studied extensively because of the ease of synthesis and range of properties exhibited. In this work, PBAE macromers were created with poly(ethylene glycol) diacrylate (PEGDA), diethylene glycol diacrylate (DEGDA), and isobutylamine. Many methods have been presented that allow control over the resulting hydrogel behavior. Here, properties were varied by combining multiple diacrylate components in the macromer synthesis step (single macromer (SM)) or through the combination of multiple macromers prior to polymerization (double macromer (DM)). The exhibited properties are a result of the hydrophilic/hydrophobic contributions of the different diacrylate mols. to the macromer. The SM systems exhibited linear degradation profiles, the rate of degradation increased as the PEGDA concentration increased. DM systems exhibited a multiphase degradation profile as a result of the combination of macromers with different hydrophilic properties. In the experiment, the researchers used many compounds, for example, Diethyleneglycoldiacrylate (cas: 4074-88-8Safety of Diethyleneglycoldiacrylate).

Diethyleneglycoldiacrylate (cas: 4074-88-8) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Safety of Diethyleneglycoldiacrylate

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Amphiphilic glycopolymer-type macromonomers for the preparation of carbohydrate-decorated polymer particles was written by Tanaka, Tomonari;Nguyen, Minh Tan;Minoda, Masahiko. And the article was included in Chemistry Letters in 2018.Electric Literature of C10H14O5 This article mentions the following:

Amphiphilic block copolymers composed of polyacrylamide (PAAm) bearing maltose (Mal) moieties, poly(N-tert-butylacrylamide) (PTBAAm) segments, and a terminal acryloyl group were synthesized by reversible addition-fragmentation chain transfer (RAFT) polymerization and thiol-ene reaction. The resulting glycopolymer-type macromonomers were used to prepare Mal-decorated polymer particles by dispersion copolymerization of the Mal-bearing block copolymers with styrene. The carbohydrate-decorated polymer particles in aqueous suspension were specifically recognized by the lectin Con A (Con A). In the experiment, the researchers used many compounds, for example, Diethyleneglycoldiacrylate (cas: 4074-88-8Electric Literature of C10H14O5).

Diethyleneglycoldiacrylate (cas: 4074-88-8) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Electric Literature of C10H14O5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Biodegradable and stimuli sensitive amphiphilic graft copolymers and their sol-gel phase transition behavior was written by Tamer, Yasemin;Yildirim, Hueseyin. And the article was included in Polymers for Advanced Technologies in 2015.Application of 4074-88-8 This article mentions the following:

PH and temperature-sensitive biodegradable poly(β-aminoester)-graft-poly(ε-caprolactone)-block-methoxy poly(ethylene glycol) (PBAE-g-PCL-b-mPEG) amphiphilic graft copolymers with different mol. weights were synthesized. The structure of these copolymers was adjusted by varying the feed ratios of ε-caprolactone to methoxy poly(ethylene glycol)s (mPEG), amine and diacrylate monomer amounts and the mol. weight of mPEG. Aqueous solutions of these copolymers formed micelles at lower concentrations; however, the concentrated solutions showed a reversible sol-gel transition property depending on both pH and temperature changes under representative physiol. conditions (pH 7.4, 37°C). The effects of the mol. weight of pH-sensitive poly(β-aminoester) block and mPEG group, the hydrophobic to hydrophilic block ratio (PCL/mPEG) and the concentration of the copolymer on the sol-gel transition were investigated. Proton NMR (¹H NMR) and gel permeation chromatog. measurements were used to characterize the structure of the synthesized copolymers. The self-assemble behavior and critical micelle concentration of the amphiphilic copolymers were estimated in phosphate buffer solution using fluorescence spectroscopy. The gelling behavior was measured by using tube inversion method. At pH 7.4, all copolymer solutions prepared 20 wt% concentration indicated sol-gel transition with increasing temperature In vitro degradation experiments displayed that the synthesized graft copolymers mostly degraded hydrolytically within 20 days under physiol. conditions. In order to investigate the potential application of synthesized hydrogels in drug delivery, Methylene Blue was used and approx. 70% of the loaded amount was released in 120 h. The findings indicate that obtained graft copolymers can be used as injectable biodegradable carriers for pharmaceutical drugs. Copyright © 2015 John Wiley & Sons, Ltd. In the experiment, the researchers used many compounds, for example, Diethyleneglycoldiacrylate (cas: 4074-88-8Application of 4074-88-8).

Diethyleneglycoldiacrylate (cas: 4074-88-8) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Application of 4074-88-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Copper-catalyzed stereoselective aminoboration of bicyclic alkenes was written by Sakae, Ryosuke;Hirano, Koji;Satoh, Tetsuya;Miura, Masahiro. And the article was included in Angewandte Chemie, International Edition in 2015.Synthetic Route of C16H20B2N2O2 This article mentions the following:

A copper-catalyzed aminoboration of bicyclic alkenes, including oxa- and azabenzonorbornadienes, gives exo-2-aminoboronates as a result of three-component addition of diboronate and O-acylhydroxylamine to the endocyclic double bond. With this method, amine and boron moieties are simultaneously introduced at an olefin with exo selectivity. Subsequent stereospecific transformations of the boryl group can provide oxygen- and nitrogen-rich cyclic mols. with motifs that may be found in natural products or pharmaceutically active compounds Moreover, a catalytic asym. variant of this transformation was realized by using a copper complex with a chiral bisphosphine ligand, namely (R,R)-Ph-BPE. In the experiment, the researchers used many compounds, for example, 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-naphtho[1,8-de][1,3,2]diazaborinine (cas: 1214264-88-6Synthetic Route of C16H20B2N2O2).

2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-naphtho[1,8-de][1,3,2]diazaborinine (cas: 1214264-88-6) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Synthetic Route of C16H20B2N2O2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

A radical approach to the copper oxidative addition problem: Trifluoromethylation of bromoarenes was written by Le, Chip;Chen, Tiffany Q.;Liang, Tao;Zhang, Patricia;MacMillan, David W. C.. And the article was included in Science (Washington, DC, United States) in 2018.Name: 2-(4-Bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane This article mentions the following:

Transition metal-catalyzed arene functionalization was widely used for mol. synthesis over the past century. In this arena, copper catalysis has long been considered a privileged platform due to the propensity of high-valent copper to undergo reductive elimination with a wide variety of coupling fragments. However, the sluggish nature of oxidative addition has limited copper’s capacity to broadly facilitate haloarene coupling protocols. Here, this copper oxidative addition problem can be overcome with an aryl radical-capture mechanism, wherein the aryl radical was generated through a silyl radical halogen abstraction. This strategy was applied to a general trifluoromethylation of aryl bromides through dual copper-photoredox catalysis. Mechanistic studies support the formation of an open-shell aryl species. In the experiment, the researchers used many compounds, for example, 2-(4-Bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 68716-49-4Name: 2-(4-Bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane).

2-(4-Bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 68716-49-4) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Name: 2-(4-Bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

LC-QTOF MS screening of more than 1000 licit and illicit drugs and their metabolites in wastewater and surface waters from the area of Bogota, Colombia was written by Hernandez, Felix;Ibanez, Maria;Botero-Coy, Ana-Maria;Bade, Richard;Bustos-Lopez, Martha Cristina;Rincon, Javier;Moncayo, Alejandro;Bijlsma, Lubertus. And the article was included in Analytical and Bioanalytical Chemistry in 2015.Recommanded Product: 2-(3-(Hydroxy(phenyl)methyl)phenyl)propanoic acid This article mentions the following:

A large screening of ∼1000 emerging contaminants, focused on licit and illicit drugs and their metabolites, has been made in urban wastewaters (both influent and effluent) and surface waters from the area of Bogota, Colombia. After a simple generic solid-phase extraction (SPE) step with Oasis hydrophilic-lipophilic balanced (HLB) cartridges, analyses were made by ultra HPLC coupled to quadrupole time-of-flight mass spectrometry (UHPLC-QTOF MS) under MS^E mode (sequential acquisition of mass spectra at low energy (LE) and high collision energy (HE)). Accurate mass measurements and the information provided by MS^E on the presence of the (de)protonated mol. and fragment ions allowed the reliable identification of the compounds detected, even without reference standards being available in some cases (tentative identification). The compounds most frequently found were acetaminophen/paracetamol, carbamazepine and its dihydro-dihydroxylated metabolite, clarithromycin, diclofenac, ibuprofen, gemfibrozil, lincomycin, losartan, valsartan, the 2 metabolites of metamizole (4-acetamido-antipyrine and 4-formylamino-antipyrine), sucralose, and cocaine and its main metabolite benzoylecgonine. Caffeine, the sweetener saccharin, and 2 hydroxylated metabolites of losartan were tentatively identified in almost all samples analyzed. Pharmaceutical lidocaine was tentatively identified and subsequently confirmed with reference standard For the 1st time, a general overview of the occurrence of drugs and their metabolites in the aquatic environment of Colombia has been reported. In the near future, target methodologies, typically based on liquid chromatog. coupled to tandem mass spectrometry (LC-MS/MS), will need to be set up for accurate and sensitive quantification of the contaminants selected on the basis on the information provided here. In the experiment, the researchers used many compounds, for example, 2-(3-(Hydroxy(phenyl)methyl)phenyl)propanoic acid (cas: 59960-32-6Recommanded Product: 2-(3-(Hydroxy(phenyl)methyl)phenyl)propanoic acid).

2-(3-(Hydroxy(phenyl)methyl)phenyl)propanoic acid (cas: 59960-32-6) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Recommanded Product: 2-(3-(Hydroxy(phenyl)methyl)phenyl)propanoic acid

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chemoselective Rhodium-Catalyzed Borylation of Bromoiodoarenes Under Mild Conditions was written by Varni, Anthony J.;Bautista, Michael V.;Noonan, Kevin J. T.. And the article was included in Journal of Organic Chemistry in 2020.Application of 68716-49-4 This article mentions the following:

A chemoselective rhodium-catalyzed borylation has been developed for the preparation of aryl boronate esters. The reaction proceeds under mild conditions with excellent selectivity for C-I bonds in bromoiodoarenes and exhibits broad functional group tolerance. This procedure can act as a complementary approach toward bifunctional arenes along with other metal-catalyzed borylations. Addnl., the reaction’s utility in the preparation of monomers for metal-catalyzed cross-coupling polymerization is demonstrated. In the experiment, the researchers used many compounds, for example, 2-(4-Bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 68716-49-4Application of 68716-49-4).

2-(4-Bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 68716-49-4) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Application of 68716-49-4

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Electro-optic characteristics of stabilized cholesteric liquid crystals with non-liquid crystalline polymer networks was written by Radka, Brian P.;Lee, Kyung Min;Godman, Nicholas P.;White, Timothy J.. And the article was included in Soft Matter in 2022.Quality Control of Diethyleneglycoldiacrylate This article mentions the following:

Extensive prior research has explored the stabilization of the CLC phase with polymer networks. These prior efforts have demonstrated both tunable and switchable electro-optic reconfiguration of the selective reflection of the CLC phase. Recently, we and other groups have detailed that polymer stabilization of the CLC phase with liquid crystalline monomers retains “structural” chirality (e.g., the chiral phase templates the morphol. of the achiral polymer network). Here, we demonstrate that structural chirality can be retained in aliphatic, non-liquid crystalline monomers. PSCLCs prepared by photoinitiated polymerization of aliphatic polymer networks exhibit reversible electro-optic responses. Facilitated by the retention of structural chirality in aliphatic stabilizing polymer networks, we explore the role of surface affinity and crosslink d. in the transfer of structural chirality to the liquid crystal media. In the experiment, the researchers used many compounds, for example, Diethyleneglycoldiacrylate (cas: 4074-88-8Quality Control of Diethyleneglycoldiacrylate).

Diethyleneglycoldiacrylate (cas: 4074-88-8) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Quality Control of Diethyleneglycoldiacrylate

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Polymeric encapsulation of liquids via plasma surface polymerization was written by Rezaei, Farzad;Dickey, Michael David;Hauser, Peter Jacob. And the article was included in Journal of Applied Polymer Science in 2020.Formula: C10H14O5 This article mentions the following:

This study introduces a new approach of liquid encapsulation using an atm. pressure plasma (APP). The technique is similar to interfacial polymerization, though here one phase is liquid (that contains unsaturated C=C bonds) and the other phase is plasma (that contains free radicals). When combined, the atm. plasma can induce surface polymerization of an acrylate-based liquid, resulting in a thin polymeric skin on top of the liquid Measurements with an at. force microscope and a spectroscopic ellipsometer estimate the thickness of the skin formed on top of di(ethylene glycol) diacrylate to be 40-50 nm. To demonstrate an application of this method, we encapsulated hemispherical capsules of reactive adhesives on a glass substrate. These adhesives are based on thiol-acrylate and thiol-acrylate-epoxy systems that react in the presence of a strong base catalyst. Plasma-induced polymerization can encapsulate, immobilize, and isolate sep. droplets of resin and the catalyst in a latent (nonreactive) state. These capsules remain latent until they rupture in response to phys. contact. A tensile testing machine reports an adhesive strength of ∼ 2 MPa for the formulated resins after curing. The capsules reported here may be useful for storing functional liquids for just-in-time release, such as contact-sensitive adhesives, on-demand lubricants, or self-healing agents. In the experiment, the researchers used many compounds, for example, Diethyleneglycoldiacrylate (cas: 4074-88-8Formula: C10H14O5).

Diethyleneglycoldiacrylate (cas: 4074-88-8) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Formula: C10H14O5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts