Tag: 200-300

Temperature-Selective Dual Radical Generation from Alkyl Diiodide: Applications to Synthesis of Asymmetric CABC Multi-Block Copolymers and Their Unique Assembly Structures was written by Zheng, Jie;Wang, Chen-Gang;Yamaguchi, Yu;Miyamoto, Michihiko;Goto, Atsushi. And the article was included in Angewandte Chemie, International Edition in 2018.COA of Formula: C10H14O5 This article mentions the following:

Temperature-selective radical generation from a newly designed alkyl diiodide (I-R²-R¹-I) was studied. R¹-I and I-R² had different reactivities for generating alkyl radicals in the presence of a tetraoctylammonium iodide (ONI) catalyst. Taking advantage of the temperature selectivity, we used the alkyl diiodide as a dual initiator in ONI-catalyzed living radical polymerization to uniquely synthesize CABC non-sym. multi-block copolymers. Because of their non-sym. structure, CABC multi-block copolymers form unique assemblies, i.e., Janus-type particles with hetero-segment coronas and flower-like particles with hetero-segment petals. In the experiment, the researchers used many compounds, for example, Diethyleneglycoldiacrylate (cas: 4074-88-8COA of Formula: C10H14O5).

Diethyleneglycoldiacrylate (cas: 4074-88-8) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.COA of Formula: C10H14O5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Enantioselective Allylation of Alkenyl Boronates Promotes a 1,2-Metalate Rearrangement with 1,3-Diastereocontrol was written by Davis, Colton R.;Luvaga, Irungu K.;Ready, Joseph M.. And the article was included in Journal of the American Chemical Society in 2021.Quality Control of 2-(4-Bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane This article mentions the following:

Alkenyl boronates add to Ir(π-allyl) intermediates with high enantioselectivity. A 1,2-metalate shift forms a second C-C bond and sets a 1,3-stereochem. relationship. The three-component coupling provides tertiary boronic esters that can undergo multiple addnl. functionalizations. An extension to trisubstituted olefins sets three contiguous stereocenters. In the experiment, the researchers used many compounds, for example, 2-(4-Bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 68716-49-4Quality Control of 2-(4-Bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane).

2-(4-Bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 68716-49-4) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Quality Control of 2-(4-Bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Synthesis and Conformational Study of Stereoisomeric 2-Phenyl-4a,5,6,7,8,8a-hexahydro-4H-1,3,4-benzoxadiazines was written by Rosling, Ari;Fulop, Ferenc;Askolin, Curt-Peter;Mattinen, Jorma. And the article was included in Journal of Chemical Research, Synopses in 1998.SDS of cas: 40571-86-6 This article mentions the following:

New stereoisomeric hexahydro-4H-1,3,4-benzoxadiazines were synthesized and their conformational behavior, ring and nitrogen inversion, was investigated by means of NMR spectroscopy and ¹H NMR simulation. In the experiment, the researchers used many compounds, for example, Trans-2-(benzylamino)cyclohexanol (cas: 40571-86-6SDS of cas: 40571-86-6).

Trans-2-(benzylamino)cyclohexanol (cas: 40571-86-6) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.SDS of cas: 40571-86-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Syntheses employing pyridyllithium reagents. New routes to 2,6-disubstituted pyridines and 6,6’disubstituted 2,2′-bipyridyls was written by Parks, J. E.;Wagner, B. E.;Holm, R. H.. And the article was included in Journal of Organometallic Chemistry in 1973.Application In Synthesis of 2-Bromo-6-(2-methyl-1,3-dioxolan-2-yl)pyridine This article mentions the following:

New 2,6-disubstituted pyridine derivatives were prepared using 6-bromo-2-lithiopyridine (I) as an intermediate. Thus, I and MeCONMe2 gave 2-acetyl-6-bromopyridine. Subsequent replacement of the 6-bromine can be effected by metal-halogen exchange or other reactions in some cases. Reactions of 6-lithio-2,2′-bipyridyl and 6,6′-dilithio-2,2′-bipyridyl are described. CuCl2 was an effective coupling agent for lithiopyridine reagents, allowing facile and high yield syntheses of substituted 2,2′-bipyridyls. In the experiment, the researchers used many compounds, for example, 2-Bromo-6-(2-methyl-1,3-dioxolan-2-yl)pyridine (cas: 49669-14-9Application In Synthesis of 2-Bromo-6-(2-methyl-1,3-dioxolan-2-yl)pyridine).

2-Bromo-6-(2-methyl-1,3-dioxolan-2-yl)pyridine (cas: 49669-14-9) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Application In Synthesis of 2-Bromo-6-(2-methyl-1,3-dioxolan-2-yl)pyridine

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Probing cavity versus surface preference of fluorescent template molecules in molecularly imprinted polystyrene microspheres was written by Sonawane, Swapnil L.;Asha, S. K.. And the article was included in Journal of Polymer Science, Part A: Polymer Chemistry in 2017.Recommanded Product: Diethyleneglycoldiacrylate This article mentions the following:

Functional polystyrene (PS) crosslinked microbeads were developed by dispersion polymerization as fluorescent molecularly imprinted polymers (MIPs) having cavities with specific recognition sites. The functional azobenzene mol. modified with pyridine was self-assembled with Pyrenebutyric acid (template mols.), and introduced during the second stage of dispersion polymerization of polystyrene. The template mol. was removed from MIP by Soxhlet using acetonitrile as solvent. Non-imprinted polymer (NIP) having no template was also synthesized for comparative study. Fluorescence spectroscopy could be used as a tool to derive insight into the location of the template mols. on the MIP or NIP. The template mols. were adsorbed on the surface of the NIPs during binding studies, which was evidenced from the pyrene excimeric emission observed at 440 nm. The template binding efficiency of the NIPs were much lower compared to MIPs. Pyrene emission from MIP upon rebinding showed typical monomeric emission in the 375-395 nm range, confirming its location in isolated cavities. In rebinding studies of the template mols., the MIPs selectively took up the template for which the cavity was designed, which demonstrated their selectivity towards template mols. © 2017 Wiley Periodicals, Inc.J. Polym. Sci., Part A: Polym.Chem. 2017. In the experiment, the researchers used many compounds, for example, Diethyleneglycoldiacrylate (cas: 4074-88-8Recommanded Product: Diethyleneglycoldiacrylate).

Diethyleneglycoldiacrylate (cas: 4074-88-8) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Recommanded Product: Diethyleneglycoldiacrylate

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Phenolics composition and contents, as the key quality parameters of table grapes, may be influenced obviously and differently in response to short-term high temperature was written by Zhang, Lingling;Li, Xingyan;Pang, Yaxing;Cai, Xinyu;Lu, Jun;Ren, Xueyan;Kong, Qingjun. And the article was included in LWT–Food Science and Technology in 2021.Computed Properties of C14H12O4 This article mentions the following:

Although the grape surface appears to be normal under high temperature during the selling period, the nutritional quality of grape might be greatly affected. Phenolics content and composition are key indicators reflective of grape′s nutritional quality. Herein, the paper investigated effects of short-term high temperature (40 °C; 2 h) on grape phenolics from five table grape varieties to evaluate grape quality. Twenty-three phenolics were identified and quantified through UHPLC-ESI-qTOF-MS2 and UHPLC-QQQ-MS2, resp. The results observed that short-term high temperature significantly reduced flavonoids in European and American varieties. In Eurasian varieties, high temperature induced the accumulation of stilbenes and flavonols compounds while lowered other compounds Myricetin 4′-methylether-3-O-rhamnoside, a differential metabolite responding to high temperature in all table grapes was screened. Combining with the anal. of mol. level, high temperature down-regulated the phenolics biosynthesis-related genes involved in phenolics metabolic pathways (flavonols, stilbenes, anthocyanins and flavan-3-ols metabolic pathways) in grapes except Muscat de Hambourg grapes, such as the expression of VvUFGT, VvANR, VvLAR, VvFLS, VvSTS, VvF3′5′H and VvAOMT. Our findings suggest that short-term high temperature during the selling period is not conducive to consumer expectations, due to the partial loss of grape nutrition quality. In the experiment, the researchers used many compounds, for example, (E)-4-(3,5-Dihydroxystyryl)benzene-1,2-diol (cas: 10083-24-6Computed Properties of C14H12O4).

(E)-4-(3,5-Dihydroxystyryl)benzene-1,2-diol (cas: 10083-24-6) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Computed Properties of C14H12O4

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Mixed diboration of alkenes in a metal-free context was written by Miralles, Nuria;Cid, Jessica;Cuenca, Ana B.;Carbo, Jorge J.;Fernandez, Elena. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2015.Reference of 1214264-88-6 This article mentions the following:

Exptl. and theor. rationalization on regioselective mixed diboration of alkenes, with the unsym. diboron reagent Bpin-Bdan (pin = pinacolate, dan = 1,8-diaminonaphthalene) , providing the protecting Bdan moiety in the internal position. E.g., reaction of PhCH:CH₂ with Bpin-Bdan in MeOH in the presence of Cs₂CO₃ at 70° gave 40% isolated yield of PhCH(Bdan)CH₂Bpin. Calculation on the energy profile for the organocatalytic diboration of propene with Bpin-Bdan diboron reagent is reported. In the experiment, the researchers used many compounds, for example, 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-naphtho[1,8-de][1,3,2]diazaborinine (cas: 1214264-88-6Reference of 1214264-88-6).

2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-naphtho[1,8-de][1,3,2]diazaborinine (cas: 1214264-88-6) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Reference of 1214264-88-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Facile inversion of configuration of N-Boc β-amino alcohols via S_N2 cyclization to oxazolidinones was written by Benedetti, F.;Norbedo, S.. And the article was included in Tetrahedron Letters in 2000.Synthetic Route of C11H21NO3 This article mentions the following:

Oxazolidinones are obtained by the cyclization of mesylates derived from N-Boc β-amino alcs. Hydrolysis of the N-(tert-butoxycarbonyl)oxazolidinones regenerates the protected amino alcs. with inverted configuration at the OH group. In the experiment, the researchers used many compounds, for example, tert-Butyl ((1R,2R)-2-hydroxycyclohexyl)carbamate (cas: 155975-19-2Synthetic Route of C11H21NO3).

tert-Butyl ((1R,2R)-2-hydroxycyclohexyl)carbamate (cas: 155975-19-2) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Synthetic Route of C11H21NO3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Investigation of poly[oligo(ethylene glycol)diacrylates] as potential stationary phases in GC was written by Kurganov, Alexander;Kanateva, Anastasiya;Shiryaeva, Valeriya;Popova, Tamara;Korolev, Alexander. And the article was included in Journal of Separation Science in 2017.Electric Literature of C10H14O5 This article mentions the following:

Poly[oligo(ethylene glycol)diacrylate]s were studied as potential candidates for application as stationary phases in capillary gas chromatog. Depending on the molar mass of the monomer, up to three different phase transitions were observed in calorimetric scans of the polymers. Two transitions were identified as the glass transition and melting of crystallites while the nature of the 3rd effect remains unknown. The new stationary phases demonstrate a good separating ability and selectivity in the viscous-elastic state, i.e. at temperatures above the glass transition and m.ps. The new polymeric stationary phases possess selectivity similar to conventional PEG columns but provide better thermal stability than conventional PEG stationary phases. In the experiment, the researchers used many compounds, for example, Diethyleneglycoldiacrylate (cas: 4074-88-8Electric Literature of C10H14O5).

Diethyleneglycoldiacrylate (cas: 4074-88-8) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Electric Literature of C10H14O5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Emissive Osmium(II) Complexes with Tetradentate Bis(pyridylpyrazolate) Chelates was written by Chang, Shih-Han;Chang, Chun-Fu;Liao, Jia-Ling;Chi, Yun;Zhou, Dong-Ying;Liao, Liang-Sheng;Jiang, Tzung-Ying;Chou, Tsao-Pei;Li, Elise Y.;Lee, Gene-Hsiang;Kuo, Ting-Yi;Chou, Pi-Tai. And the article was included in Inorganic Chemistry in 2013.Electric Literature of C9H10BrNO2 This article mentions the following:

A tetradentate bis(pyridylpyrazolate) chelate, L, is assembled by connecting two bidentate 3-(trifluoromethyl)-5-(2-pyridyl)pyrazole chelates at the 6 position of the pyridyl fragment with a phenylamido appendage. This chelate was then used in the synthesis of three osmium(II) complexes, namely, [Os(L)(CO)₂] (4), [Os(L)(PPh₂Me)₂] (5), and [Os(L)(PPhMe₂)₂] (6). Single-crystal x-ray structural analyses were executed on 4 and 5 to reveal the bonding arrangement of the L chelate. Phosphine-substituted derivatives 5 and 6 are highly emissive in both solution and the solid state, and their photophys. properties were measured and discussed on the basis of computational approaches. For application, fabrication and anal. of organic light-emitting diodes (OLEDs) were also carried out. The OLEDs using 5 and 6 as dopants exhibit saturated red emission with maximum external quantum efficiencies of 9.8% and 9.4%, resp., which are higher than that of the device using [Ir(piq)₃] as a red-emitting reference sample. Moreover, for documentation, 5 and 6 also achieve a maximum brightness of 19540 cd·m^-2 at 800 mA·cm^-2 (11.6 V) and 12900 cd·m^-2 at 500 mA·cm^-2 (10.5 V), resp. In the experiment, the researchers used many compounds, for example, 2-Bromo-6-(2-methyl-1,3-dioxolan-2-yl)pyridine (cas: 49669-14-9Electric Literature of C9H10BrNO2).

2-Bromo-6-(2-methyl-1,3-dioxolan-2-yl)pyridine (cas: 49669-14-9) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Electric Literature of C9H10BrNO2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts