Tag: 200-300

Sotto, Nicolas;Billamboz, Muriel;Chevrin-Villette, Carole;Len, Christophe published 《Selective Pinacol Coupling on Regeneratable Supported Acids in Sole Water》. The research results were published in《Journal of Organic Chemistry》 in 2015.Synthetic Route of C14H14O2 The article conveys some information:

Efficient pinacol coupling was developed in water, using a reusable heterogeneous supported acid source and zinc as cheap available metal source. This medium can be easily regenerated up to 10-fold without loss of activity. Moreover, supported acids enhance the selectivity of the pinacol coupling reaction compared with homogeneous acids. Thus, e.g., pinacol coupling of 4-bromobenzaldehyde in water using Zn as electron donor and Amberlyst 15 as proton source afforded 1,2-bis(4-bromophenyl)-1,2-ethanediol (82%, DL/meso = 29/71) + 4-bromobenzyl alc. (11%). To complete the study, the researchers used rel-(1R,2S)-1,2-Diphenylethane-1,2-diol (cas: 579-43-1) .

rel-(1R,2S)-1,2-Diphenylethane-1,2-diol(cas: 579-43-1 Synthetic Route of C14H14O2) has been used in the preparation of trans-methyl meso-hydrobenzoin phosphite.

Reference:
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Li, Qi;Chai, Changsheng;Zhao, Linguo published 《Biodegradation of Endocrine Disrupting Chemicals with Laccase Isozymes from Recombinant Pichia pastori》. The research results were published in《Catalysis Letters》 in 2022.COA of Formula: C14H22O The article conveys some information:

In this paper, five recombinant strains: GS115-LacA, GS115-LacB, GS115-LacC, KM71H-Lcc1 and GS115-Lcc2 were selected to produce laccase isoenzymes with high activities, which reached 13,001 U/L, 10,254 U/L, 11,495 U/L, 9924 U/L and 10,031 U/L on 15th, resp. Then, we investigated the specificity of several recombinant laccase isoenzymes for the degradation of endocrine disrupting chems. (phenolic compounds). The results showed that LacB had the most efficient in degradation of bisphenol A and octyl phenol, while Lcc1 degraded 4-n-octylphenol, gossypol and hydroquinone better. Finally, the effects of degradation conditions were optimized, which shown that the degradation rates of phenolic compounds increased with the optimum temperature and pH by different laccases were different, which were closely related to their enzymic properties. Under the optimum reaction conditions, the degradation rate of bisphenol A, gossypol, 4-n-octylphenol, octyl phenol and hydroquinone were 95.4%, 93.2%, 89.6%, 71.0% and 91.9% at 8 h, 8 h, 12 h, 24 h and 1 h, resp. Furthermore, the recombinant laccases were used to degrade phenolic compounds in several laccase/mediator systems, which ABTS and vanillin showed most enhancement on degradation rates and reduction of degradation times. In LacB-ABTS and Lcc1-guaiacol/vanillin systems, the degradation rates of five phenolic compounds reached the maximum with totally 100% within 4 h. All of the results open up promising perspectives for the degradation and oxidative biotransformation of typical phenolic pollutants in the environment. Graphical Abstract: [graphic not available: see fulltext]. The experimental procedure involved many compounds, such as 4-tert-Octylphenol (cas: 140-66-9) .

4-tert-Octylphenol(cas: 140-66-9) is a common environmental pollutant showing weak estrogenic effects.COA of Formula: C14H22O It has been shown to cause harm to vertebrate male reproductive systems.

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Minakawa, Maki;Sakurai, Yuya published 《Bismuth(III) Triflate-Catalyzed Intermolecular Cyclization of Phenols with Diols: Direct Access to O-Heterocycles》 in 2022. The article was appeared in 《Synlett》. They have made some progress in their research.SDS of cas: 599-64-4 The article mentions the following:

A direct access to O-heterocycles e.g., I by Bi(OTf)₃-catalyzed intermol. cyclization of phenols such as naphthalene-2,6-diol, 2-naphthol, 4-(2-phenylpropan-2-yl)phenol, etc. with diols such as, propane-1,3-diol, pentane-2,4-diol, 2,5-dimethylhexane-2,5-diol, etc.was described. Catalytic dehydrative tandem formation of C-O and C-C bonds was achieved by using a Bi(OTf)₃ catalyst without any additives. The catalytic intermol. cyclization of phenols with various diols proceeded to give the corresponding chromanes e.g., I in up to 91% yield and/or furan derivatives II [R = H, Me; R¹ = iso-Pr, ethyl; R² = H, Me; R³ = H, COOMe] up to 66% yield. The experimental procedure involved many compounds, such as 4-(2-Phenylpropan-2-yl)phenol (cas: 599-64-4) .

4-(2-Phenylpropan-2-yl)phenol(cas:599-64-4) is a natural product found in Panax ginseng.SDS of cas: 599-64-4 4-(2-Phenylpropan-2-yl)phenol is a useful reagent for preparing and characterizing aromatic polyphosphonates as high refractive index polymers.

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COA of Formula: C14H14O2《Amine Catalysis for the Organocatalytic Diboration of Challenging Alkenes》 was published in 2016. The authors were Farre, Albert;Soares, Kaline;Briggs, Rachel A.;Balanta, Angelica;Benoit, David M.;Bonet, Amadeu, and the article was included in《Chemistry – A European Journal》. The author mentioned the following in the article:

The generation of in situ sp²-sp³ diboron adducts has revolutionized the synthesis of organoboranes. Organocatalytic diboration reactions have represented a milestone in terms of unpredictable reactivity of these adducts. However, current methodologies have limitations in terms of substrate scope, selectivity and functional group tolerance. Here a new methodol. based on the use of simple amines as catalyst is reported. This methodol. provides a completely selective transformation overcoming current substrate scope and functional/protecting group limitations. Mechanistic studies have been included in this report. To complete the study, the researchers used rel-(1R,2S)-1,2-Diphenylethane-1,2-diol (cas: 579-43-1) .

rel-(1R,2S)-1,2-Diphenylethane-1,2-diol(cas: 579-43-1 COA of Formula: C14H14O2) has been used in the preparation of trans-methyl meso-hydrobenzoin phosphite.

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Chen, Zhao;Li, Yuanli;Liu, Xiaomin;Cui, Zhenggang published 《Dialkyl Sulfobetaine Surfactants Derived from Guerbet Alcohol Polyoxypropylene-Polyoxyethylene Ethers for SP Flooding of High Temperature and High Salinity Reservoirs》. The research results were published in《Journal of Surfactants and Detergents》 in 2021.Electric Literature of C16H34O The article conveys some information:

Dialkyl hydroxypropyl sulfobetaine (HSB) surfactants, C16GA-(PO)5-(EO)3-HSB and C24GA-(PO)10-(EO)10-HSB, were synthesized from Guerbet alcs. (GA) polyoxypropylene-polyoxyethylene (PO-EO) ethers and their behaviors in surfactant-polymer (SP) flooding of high temperature and high salinity reservoirs were examined and compared with their anionic hydroxypropyl sulfonate (HS) counterparts, C16GA-(PO)5-(EO)3-HS and C24GA-(PO)10-(EO)10-HS. The PO-EO chain embedded improves their aqueous solubility, and the sulfobetaines show better salt resistance than sulfonates. For a reservoir condition of total salinity 19,640 mg L-1 and 60-80°C, C16GA-(PO)5-(EO)3-HSB alone can reduce crude oil/connate water interfacial tension (IFT) to ultralow at 0.25-5 mM, which can be further widened to 0.1-5 mM by mixing with dodecylhexyl (C12+6) glyceryl ether hydroxypropyl sulfobetaine (C12+6GE-HSB), a slightly hydrophobic surfactant. C24GA-(PO)10-(EO)10-HSB is more hydrophobic for the specified reservoir condition, however, by mixing with hexadecyl di-Me hydroxypropyl sulfobetaine (C16HSB), a hydrophilic surfactant, ultralow IFT can also be achieved at a total concentration of 0.25-5 mM. The anionic counterparts can also reduce IFT to ultralow by mixing with C12+6GE-HSB and C16HSB, resp. Moreover, the optimum binary mixture, C16GA-(PO)5-(EO)3-HSB/C12+6GE-HSB at a molar fraction ratio of 0.6/0.4, can keep the neg. charged solid surface water-wet (θw = 12-23°) in a wide concentration range, and can still achieve ultralow IFT after stored at 90°C for 90 days (initially 5 mM), which overall are favor of improving oil displacement efficiency at high temperature and high salinity reservoir conditions. The experimental procedure involved many compounds, such as 2-Hexyl-1-decanol (cas: 2425-77-6) .

2-Hexyl-1-decanol(cas: 2425-77-6) is a fatty acid that is found in the essential oils of plants and has been shown to have fungicidal properties.Electric Literature of C16H34O It has also been shown to inhibit the growth of Candida glabrata when used as a cationic surfactant.

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Adeleye, Temitope Adewumi;Ajiboye, Clement Odunayo;Ojah, Emmanuel Onah;Okesanjo, Toyin Patrick;Moronkola, Dorcas Olufunke published 《Composition and antioxidant potential of leaf and stem essential oils from Nigerian Indigofera spicata Forssk》. The research results were published in《Journal of Medicinal Plants Research》 in 2021.Synthetic Route of C16H34O The article conveys some information:

The chem. compositions and antioxidant evaluation of the essential oils (EOs) obtained by hydrodistillation from the leaf and stem of Indigofera spicata Forssk (Fabaceae) grown in Nigeria have been studied. The EOs were analyzed using gas chromatog. coupled with mass spectrometry (GC-MS) and the antioxidant potential was determined using 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging ability method. The essential oils from the leaf and stem obtained in 0.007% and 0.009% yield have been found to contain 18 and 17 compounds resp. 13 compounds identified in the stem EOs make 90.2% of it. Sesquiterpenes (49.2%) and alcs. (30.7%) are dominant classes of compounds in the leaf EOs, with the most abundant compounds as caryophyllene (38.2%), humulene (6.2%) and m-eugenol (27.5%). Whereas esters (47.2%), and monoterpenoids (20.8%) dominate the stem essential oils with major constituents as linalyl acetate (23.9%), α-terpinyl acetate (12.8%), 3,5,5-trimethyhexyl acetate (9.4%), and linalool (20.8%). Common to both EOs were linalool, (leaf, 1.9%) caryophyllene (stem 5.9%), linanyl acetate (leaf, 2.5%). Comparison of the composition pattern of the leaf and stem EOs of I. spicata revealed significant qual. and quant. differences. Monoterpenes, sesquiterpenoid, diterpenoid, epoxide and ether were exclusive to the leaf oil while saturated, unsaturated hydrocarbons and anhydride were found only in the stem oil. The IC₅₀ values of antioxidant evaluations show the leaf EO (36.97μg/mL) has more potential than the stem oil (39.89μg/mL) and comparable to that of the controls Vitamin C and Butylhydroxyl Anisole with IC₅₀ values 24.20 and 24.21μg/mL resp. Most of these identified compounds have been known for various pharmacol. activities such as antioxidant, antitumor, anti-inflammatory, even as fragrances and the antioxidant potential of the oils justify the ethno-medicinal uses of I. spicata. The experimental procedure involved many compounds, such as 2-Hexyl-1-decanol (cas: 2425-77-6) .

2-Hexyl-1-decanol(cas: 2425-77-6) is a fatty acid that is found in the essential oils of plants and has been shown to have fungicidal properties.Synthetic Route of C16H34O It has also been shown to inhibit the growth of Candida glabrata when used as a cationic surfactant.

Reference:
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Zhu, Lihui;Li, Jiasheng;Yang, Jun;Au-Yeung, Ho Yu published 《Cross dehydrogenative C-O coupling catalysed by a catenane-coordinated copper(I)》. The research results were published in《Chemical Science》 in 2020.Formula: C15H16O The article conveys some information:

Catalytic activity of copper(I) complexes supported by phenanthroline-containing catenane ligands towards a new C(sp3)-O dehydrogenative cross-coupling of phenols ROH (R = Ph, 4-(2-phenylpropan-2-yl)phenyl, 2-formyl-4-methoxyphenyl, etc.) and bromodicarbonyls R¹C(O)CH(Br)C(O)R² (R¹ = Me, Ph, OBn, etc.; R² = OEt, OMe, OtBu, OBn) is reported. As the phenanthrolines are interlocked by the strong and flexible mech. bond in the catenane, the active catalyst with an open copper coordination site can be revealed only transiently and the stable, coordinatively saturated Cu(I) pre-catalyst is quickly regenerated after substrate transformation. Compared with a control Cu(I) complex supported by non-interlocked phenanthrolines, the catenane-supported Cu(I) is highly efficient with a broad substrate scope, and can be applied in gram-scale transformations without a significant loss of the catalytic activity. This work demonstrates the advantages of the catenane ligands that provide a dynamic and responsive copper coordination sphere, highlighting the potential of the mech. bond as a design element in transition metal catalyst development. To complete the study, the researchers used 4-(2-Phenylpropan-2-yl)phenol (cas: 599-64-4) .

4-(2-Phenylpropan-2-yl)phenol(cas:599-64-4) is a natural product found in Panax ginseng.Formula: C15H16O 4-(2-Phenylpropan-2-yl)phenol is a useful reagent for preparing and characterizing aromatic polyphosphonates as high refractive index polymers.

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Name: rel-(1R,2S)-1,2-Diphenylethane-1,2-diolIn 2016, Archelas, Alain;Zhao, Wei;Faure, Bruno;Iacazio, Gilles;Kotik, Michael published 《Epoxide hydrolase-catalyzed enantioselective conversion of trans-stilbene oxide: Insights into the reaction mechanism from steady-state and pre-steady-state enzyme kinetics》. 《Archives of Biochemistry and Biophysics》published the findings. The article contains the following contents:

A detailed kinetic study based on steady-state and pre-steady-state measurements is described for the highly enantioselective epoxide hydrolase Kau2. The enzyme, which is a member of the α/β-hydrolase fold family, preferentially reacts with the (S,S)-enantiomer of trans-stilbene oxide (TSO) with an E value of ∼200. The enzyme follows a classical two-step catalytic mechanism with formation of an alkyl-enzyme intermediate in the first step and hydrolysis of this intermediate in a rate-limiting second step. Tryptophan fluorescence quenching during TSO conversion appears to correlate with alkylation of the enzyme. The steady-state data are consistent with (S,S) and (R,R)-TSO being two competing substrates with marked differences in k_cat and K_m values. The high enantiopreference of the epoxide hydrolase is best explained by pronounced differences in the second-order alkylation rate constant (k₂/K_S) and the alkyl-enzyme hydrolysis rate k₃ between the (S,S) and (R,R)-enantiomers of TSO. Our data suggest that during conversion of (S,S)-TSO the two active site tyrosines, Tyr¹⁵⁷ and Tyr²⁵⁹, serve mainly as electrophilic catalysts in the alkylation half-reaction, polarizing the oxirane oxygen of the bound epoxide through hydrogen bond formation, however, without fully donating their hydrogens to the forming alkyl-enzyme intermediate.rel-(1R,2S)-1,2-Diphenylethane-1,2-diol (cas: 579-43-1) were involved in the experimental procedure.

Desymmetrization of rel-(1R,2S)-1,2-Diphenylethane-1,2-diol(cas:579-43-1 Name: rel-(1R,2S)-1,2-Diphenylethane-1,2-diol) using chiral phosphine catalyst has been reported. Conversion of meso-hydrobenzoin to trans-stillbene oxide by treatment with an aryl sulfonyl chloride and aqueous sodium hydroxide has been reported.

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Ai, Han-Jun;Zhang, Youcan;Zhao, Fengqian;Wu, Xiao-Feng published 《Rhodium-Catalyzed Carbonylative Synthesis of Aryl Salicylates from Unactivated Phenols》 in 2020. The article was appeared in 《Organic Letters》. They have made some progress in their research.SDS of cas: 599-64-4 The article mentions the following:

In the presence of RhCl₃ and 1,2-bis(dicyclohexylphosphino)ethane (dcpe), phenols underwent carbonylative esterification reactions with CO mediated by TEMPO in 1.4-dioxane/toluene to yield aryl salicylates such as Ph salicylate. Under similar conditions, but using 1,3-bis(diphenylphosphino)propane as the ligand, di-Ph carbonate was obtained as the major product. The mechanism of the reaction was studied using the reactions of potential intermediates and using kinetic isotope effects.4-(2-Phenylpropan-2-yl)phenol (cas: 599-64-4) were involved in the experimental procedure.

4-(2-Phenylpropan-2-yl)phenol(cas:599-64-4) is a natural product found in Panax ginseng.SDS of cas: 599-64-4 4-(2-Phenylpropan-2-yl)phenol is a useful reagent for preparing and characterizing aromatic polyphosphonates as high refractive index polymers.

Reference:
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Application of 140-66-9《Identification of potential toxicants in sediments from an industrialized area in Pohang, South Korea: Application of a cell viability assay of microalgae using flow cytometry》 was published in 2021. The authors were An, Seong-Ah;Hong, Seongjin;Lee, Junghyun;Cha, Jihyun;Lee, Sunggyu;Moon, Hyo-Bang;Giesy, John P.;Khim, Jong Seong, and the article was included in《Journal of Hazardous Materials》. The author mentioned the following in the article:

Potential toxicants in sediments collected from an industrialized bay of Korea were identified by use of effect-directed anal. (EDA). Three marine microalgal bioassays (Dunaliella tertiolecta, Isochrysis galbana, and Phaeodactylum tricornutum) with diverse endpoints were employed. Initial screening of raw organic extracts of sediments indicated large variations among locations and species in a traditional endpoint “inhibition of growth”. After fractionation, inhibition of growths increased significantly, particularly in some fractions containing aromatics with log K_OW 5-6 (F2.6). While viabilities of cells were adversely affected in more fractions, including F2.6-F2.7 (log K_OW 5-7) and F3.5-F3.6 (log K_OW 4-6). Among the several endpoints of viability, esterase activity seemed to be more sensitive, followed by integrity of cell membranes, chlorophyll a, cell size, and intracellular complexity. Instrumental analyses indicated that toxicities to microalgae observed in F2.7 could not be fully explained by target PAHs. Full-scan screening anal. using GC-QTOFMS identified 58 compounds in F2.7 with matching scores ≥90%. Based on toxic potencies for these compounds predicted by ECOSAR, several causative agents, including 1-phenylpyrene, dibenz[a,c]anthracene, and picene were suggested. Overall, viability of microalgae provided sensitive and high-resolution toxicity screening of samples into integrative assessment of sediment.4-tert-Octylphenol (cas: 140-66-9) were involved in the experimental procedure.

4-tert-Octylphenol(cas: 140-66-9) is a common environmental pollutant showing weak estrogenic effects.Application of 140-66-9 It has been shown to cause harm to vertebrate male reproductive systems.

Reference:
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