Tag: 200-300

On July 7, 2010, Taylor, Grahame N.; Matherly, Ron published an article.Recommanded Product: 2,2′,2”-(1,3,5-Triazinane-1,3,5-triyl)triethanol The title of the article was Gas chromatography mass spectrometric analysis of chemically derivatized hexahydrotriazine-based hydrogen sulfide scavengers: 1. And the article contained the following:

A gas chromatog.-mass spectrometry method of assaying 1,3,5-tris(2-hydroxyethyl)hexahydro-s-triazine in laboratory and field fluids is presented. This method involves the tris-trifluoroacetylation of anhydrous 1,3,5-tris(2-hydroxyethyl)hexahydro-s-triazine to avoid the undesired thermolysis to oxazolidine. The experimental process involved the reaction of 2,2′,2”-(1,3,5-Triazinane-1,3,5-triyl)triethanol(cas: 4719-04-4).Recommanded Product: 2,2′,2”-(1,3,5-Triazinane-1,3,5-triyl)triethanol

The Article related to hexahydrotriazine based hydrogen sulfide scavenger assaying gc mass spectrometry, trifluoroacetylation hexahydrotriazine based hydrogen sulfide scavenger assaying gc ms, Organic Analytical Chemistry: Determinations and other aspects.Recommanded Product: 2,2′,2”-(1,3,5-Triazinane-1,3,5-triyl)triethanol

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Kowalski, Piotr S.; Capasso Palmiero, Umberto; Huang, Yuxuan; Rudra, Arnab; Langer, Robert; Anderson, Daniel G. published an article in 2018, the title of the article was Ionizable amino-polyesters synthesized via ring opening polymerization of tertiary amino-alcohols for tissue selective mRNA delivery.Electric Literature of 4719-04-4 And the article contains the following content:

The utility of mRNA (mRNA) as a therapy is gaining a broad interest due to its potential for addressing a wide range of diseases, while effective delivery of mRNA mols. to various tissues still poses a challenge. This study reports on the design and characterization of new ionizable amino-polyesters (APEs), synthesized via ring opening polymerization (ROP) of lactones with tertiary amino-alcs. that enable tissue and cell type selective delivery of mRNA. With a diverse library of APEs formulated into lipid nanoparticles (LNP), structure-activity parameters crucial for efficient transfection are established and APE-LNPs are identified that can preferentially home to and elicit effective mRNA expression with low in vivo toxicity in lung endothelium, liver hepatocytes, and splenic antigen presenting cells, including APE-LNP demonstrating nearly tenfold more potent systemic mRNA delivery to the lungs than vivo-jetPEI. Adopting tertiary amino-alcs. to initiate ROP of lactones allows to control polymer mol. weight and obtain amino-polyesters with narrow mol. weight distribution, exhibiting batch-to-batch consistency. All of which highlight the potential for clin. translation of APEs for systemic mRNA delivery and demonstrate the importance of employing controlled polymerization in the design of new polymeric nanomaterials to improve in vivo nucleic acid delivery. The experimental process involved the reaction of 2,2′,2”-(1,3,5-Triazinane-1,3,5-triyl)triethanol(cas: 4719-04-4).Electric Literature of 4719-04-4

The Article related to aminopolyester synthesis tertiary amino alc mrna delivery tissue, biomaterials, messenger rna, nucleic acid delivery, polyesters, polymeric nanoparticles, Pharmaceuticals: Formulation and Compounding and other aspects.Electric Literature of 4719-04-4

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On September 30, 2021, Nishad, Jay Hind; Singh, Arti; Gautam, Veer Singh; Kumari, Puja; Kumar, Jitendra; Yadav, Monika; Kharwar, Ravindra Nath published an article.Recommanded Product: 2,4-Di-tert-butylphenol The title of the article was Bioactive potential evaluation and purification of compounds from an endophytic fungus Diaporthe longicolla, a resident of Saraca asoca (Roxb.) Willd.. And the article contained the following:

An endophytic fungus (L3), isolated from the leaf tissues of Saraca asoca was identified as D. longicolla by microscopic and mol. methods. The crude extracts of D. longicolla revealed to harbor seven compounds in GC-MS anal. which was subjected to a thin layer chromatog. (TLC) for purification and separation of bioactive ingredients. The partially purified fraction from TLC displayed the presence of 2-tridecene (Z) (RT-14.50), 5-tridecene (E) (RT-16.65) and 2,4-di-tert-butylphenol (RT-13.92) in GC-MS. High-performance liquid chromatog. (HPLC) was performed to further purify the constituents which led to the collection of 2,4-di-tert-Bu phenol (RT-2.34) with excellent antioxidant activity and antibacterial activity against methicillin resistance Staphylococcus aureus (MRSA). The experimental process involved the reaction of 2,4-Di-tert-butylphenol(cas: 96-76-4).Recommanded Product: 2,4-Di-tert-butylphenol

The Article related to saraca asoca diaporthe longicolla resident compound purification bioactivity, bioactivity evaluation, compound purification, d. longicolla, gc–ms, hplc, Plant Biochemistry: Composition and Products and other aspects.Recommanded Product: 2,4-Di-tert-butylphenol

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On June 30, 2006, Fekete, Agnes; Hertkorn, Norbert; Frommberger, Moritz; Lahaniatis, Majlinda R.; Kettrup, Antonius; Schmitt-Kopplin, Philippe published an article.SDS of cas: 4719-04-4 The title of the article was Development of a capillary electrophoresis-mass spectrometry method for the determination of formaldehyde releasers as their hydrolysis products and amino alcohols from metal working fluids. And the article contained the following:

Metal working fluids (MWFs) are widely used as lubricants and coolants for different industrial operations. Biocides are ingredients of MWFs to control the microbial growth; derivatives of hexahydrotriazines and oxazolidines are generally used. Because of the lack of appropriate characterization, an existing capillary electrophoretic method for their quantification was improved. During the process of optimization, it became clear that hydrolysis products, derivatives of amino alcs., severely interfere with the separation procedure. Since indirect-UV detection lacked the required selectivity, mass-selective detection was employed. NMR and MS established the absence of amino alcs. in the original products. The aqueous solutions of the biocides stored for extended time remained amino alc.-free, suggesting that these amino alcs. are formed from the biocides during the capillary electrophoretic separation The observation of narrow and sym. peaks indicated hydrolysis, and the polarity of the products implied favorable conditions for capillary electrophoretic separation Methods were optimized for the anal. of the amino alcs., the hydrolytic products of the formaldehyde releasers, using indirect-UV and MS detection. This method was extended to other likely solutes used as alk.-reserve ingredients. The analytes were separated within 9 min with a high precision of migration times (the RSDs were <1.5%). When quantifying from mobility scale, the calibration curves produced linearity with regression coefficients at 0.990-0.999. The detection limit was <1 mg/L in the case of MS detection. The influence of water-based MWF was also studied, and no matrix effect on the migration of the analytes and on the peak areas was observed The experimental process involved the reaction of 2,2',2''-(1,3,5-Triazinane-1,3,5-triyl)triethanol(cas: 4719-04-4).SDS of cas: 4719-04-4

The Article related to metal working fluid biocide hydrolytic product analysis electrophoresis ms, capillary electrophoresis mass spectrometry amino alc metal working fluid, Organic Analytical Chemistry: Determinations and other aspects.SDS of cas: 4719-04-4

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Moni, Sivakumar Sivagurunathan; Alam, Mohammad Firoz; Makeen, Hafiz A.; Alhazmi, Hassan A.; Sultan, Muhammad; Siddiqui, Rahimullah; Jabeen, Aamena; Sanobar, Syeda; Alam, Shamsher Md.; Ur Rehman, Zia; Elmobark, Mohamed Eltyep; Madkhali, Osama; Haque, Anzarul; Albratty, Mohammed published an article in 2021, the title of the article was Solvent extraction, spectral analysis and antibacterial activity of the bioactive crystals of Sargassum aquifolium (Turner) C.Agardh from Red Sea.HPLC of Formula: 96-76-4 And the article contains the following content:

The purpose of this study was to investigate the chem. composition and anti-bacterial properties of the bioactive principles of Sargassum aquifolium (Turner) C. Agardh, a brown seaweed in Red sea of Jazan province, Kingdom of Saudi Arabia. Crystals were obtained from the petroleum ether extract of Sargassum aquifolium and subjected to chem. tests, FTIR spectroscopic anal. and NMR anal. to identify their chem. composition, and to study their antibacterial properties against selected human pathogenic bacteria. In addition, GC-MS anal. was performed to identify the bioactive compounds in the crude petroleum ether extract Results of the antibacterial effect of the crystal analyte showed a wide spectrum of activity against the screened human pathogenic bacteria. The experimental process involved the reaction of 2,4-Di-tert-butylphenol(cas: 96-76-4).HPLC of Formula: 96-76-4

The Article related to sargassum antibacterial, red sea, antibacterial, brown alga, crystals, phyto constituents, saponins, tannins, Plant Biochemistry: Composition and Products and other aspects.HPLC of Formula: 96-76-4

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Pretty, Jack; Glaser, Robert; Jones, Johnny III; Lunsford, R. Alan published an article in 2004, the title of the article was A technique for the identification and direct analysis of hexahydro-1,3,5-tris(2-hydroxyethyl)-s-triazine in metalworking fluids using electrospray-mass spectrometry.COA of Formula: C9H21N3O3 And the article contains the following content:

Hexahydro-1,3,5-tris(2-hydroxyethyl)-s-triazine is a widely used biocide in metalworking fluids that resists direct quantification in many anal. methods due to instability. It can be detected in electrospray-mass spectrometry (ES-MS) due to the formation of a charged and relatively stable adduct with the sodium ion. This adduct produces a distinct ion spectrum via collision-induced fragmentation, which should promote specific detection of the analyte in complex matrixes. ES-MS detection of the analyte added to, or already present in, metalworking fluid samples at μg mL-1 levels is demonstrated. Parameters affecting the formation and detection of the sodium adduct, including choice of solvent, alkalinity, and sodium ion level are explored. Linearity of response in flow injection mode is demonstrated. The experimental process involved the reaction of 2,2′,2”-(1,3,5-Triazinane-1,3,5-triyl)triethanol(cas: 4719-04-4).COA of Formula: C9H21N3O3

The Article related to hexahydrohydroxyethyltriazine determination metalworking fluid electrospray mass spectrometry, Organic Analytical Chemistry: Determinations and other aspects.COA of Formula: C9H21N3O3

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On May 31, 2020, Thekkangil, Aswani; Suchithra, T. V. published an article.Quality Control of 2,4-Di-tert-butylphenol The title of the article was Antidermatophytic lead compounds from Streptomycetes albidoflavus STV1572a against Tinea infections by Tricophyton mentagrophytes. And the article contained the following:

Dermatophytic infection is a psychol. burden due to its inefficacy in prolonged effectiveness during its course of treatment. The present study reports a novel antidermatophytic property from actinomycetes of wetlands soil. Total of 37 Streptomyces isolates were screened for antidermatophytic activity against Trichophyton mentagrophytes. The best isolate with 100% novel activity, was characterized and designated as Streptomyces albidoflavus STV1572a. Antidermatophytic compounds extracted from the mentioned strain were partially purified by chromatog. techniques. Further, it was characterized using UV-Vis spectroscopy, FTIR spectroscopy, and GC-MS anal. Compound identified were, Phenol 2, 4-bis (1, 1-dimethylethyl), 9-octadecene (E), E-14- Hexadecenal, e-15- Heptadecenal, 1- Heneicosanol, Hypophosphonousdichloride bis (1, 1-dimethylethyl) and Heptadecyl trifluoroacetate. To sum up, this study illustrates an antidermatophytic lead compounds that pave its way for further purification and characterization of these compounds for their optimum utilization for antimycotic purposes. The experimental process involved the reaction of 2,4-Di-tert-butylphenol(cas: 96-76-4).Quality Control of 2,4-Di-tert-butylphenol

The Article related to streptomycetes tricophyton tinea antidermatophytics, antidermatophytic activity, antimycotic compound, streptomyces sp., trichophyton mentagrophytes, wetland soil, Microbial, Algal, and Fungal Biochemistry: Other and other aspects.Quality Control of 2,4-Di-tert-butylphenol

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On December 31, 2021, Chen, Guzhong; Song, Zhen; Qi, Zhiwen published an article.Product Details of 4719-04-4 The title of the article was Transformer-convolutional neural network for surface charge density profile prediction: Enabling high-throughput solvent screening with COSMO-SAC. And the article contained the following:

A deep learning (DL) method for quickly predicting surface charge d. profiles (σ-profile) and cavity volumes (VCOSMO) of mols. for the COSMO-SAC model is developed. The mol. fingerprints are derived from the encoder state of a Transformer model pre-trained on the ChEMBL database, which allows transfer learning from large-scale unlabeled data and improve generalization performance by developing better mol. fingerprints for building models with significantly smaller datasets. Employing the pre-trained mol. fingerprints, a convolutional neural network (CNN) model for the σ-profile and VCOSMO prediction is trained and tested on the VT-2005 database. The obtained Transformer-CNN model presents superior performance to the GC-COSMO approach and enables the prediction of σ-profile and VCOSMO of millions of mols. in only a few minutes. Taking advantages of the model, a high-throughput solvent screening framework based on COSMO-SAC is further proposed and exemplified by searching sustainable solvent for the deterpenation process of citrus essential oils. The experimental process involved the reaction of 2,2′,2”-(1,3,5-Triazinane-1,3,5-triyl)triethanol(cas: 4719-04-4).Product Details of 4719-04-4

The Article related to deep learning convolutional neural network charge density, History, Education, and Documentation: Education and other aspects.Product Details of 4719-04-4

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On July 31, 2007, Li, Lin-Feng; Liu, Guangren; Wang, Jing published an article.Computed Properties of 4719-04-4 The title of the article was Patch test in Chinese patients with cosmetic allergic contact dermatitis to common cosmetic allergens from a European cosmetic series. And the article contained the following:

The frequency of patch test (PT) reactions to common cosmetic allergens (CCAs) in Chinese patients with cosmetic allergic contact dermatitis (CACD) was investigated. A total of 655 consecutive patients with eczema patch tested with a modified European standard series and 20 of 48 CCA from a European cosmetic series during a 2-yr period in Peking University Third Hospital, Beijing, China, were analyzed. Five hundred and ninety-nine of 655 (91.5%) patients finished the study. Among them, 93 (15.5%) patients had suspected CACD. Only 48 of 93 (42%) suspected CACD were confirmed. Other 45 patients (48.4%) developed their dermatitis from beauty shop or beauty center; CACD could not be diagnosed by PT the suspected cosmetics as is, and the patients were not willing to re-use the suspected cosmetics. Because Chinese regulations do not require the cosmetic manufactures labeling the cosmetic ingredients in their products, CACD cannot be diagnosed by CCA PT. The experimental process involved the reaction of 2,2′,2”-(1,3,5-Triazinane-1,3,5-triyl)triethanol(cas: 4719-04-4).Computed Properties of 4719-04-4

The Article related to allergic contact dermatitis eczema cosmetic allergen, Essential Oils and Cosmetics: Skin Preparations and other aspects.Computed Properties of 4719-04-4

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On October 6, 2020, Liu, Runzeng; Mabury, Scott A. published an article.Synthetic Route of 96-76-4 The title of the article was Synthetic phenolic antioxidants: A review of environmental occurrence, fate, human exposure, and toxicity. And the article contained the following:

A review. Synthetic phenolic antioxidants (SPAs) are widely used in various industrial and com. products to retard oxidative reactions and lengthen product shelf life. In recent years, numerous studies have been conducted on the environmental occurrence, human exposure, and toxicity of SPAs. Here, we summarize the current understanding of these issues and provide recommendations for future research directions. SPAs have been detected in various environmental matrixes including indoor dust, outdoor air particulates, sea sediment, and river water. Recent studies have also observed the occurrence of SPAs, such as 2,6-di-tert-butyl-4-methylphenol (BHT) and 2,4-di-tert-butyl-phenol (DBP), in humans (fat tissues, serum, urine, breast milk, and fingernails). In addition to these parent compounds, some transformation products have also been detected both in the environment and in humans. Human exposure pathways include food intake, dust ingestion, and use of personal care products. For breastfeeding infants, breast milk may be an important exposure pathway. Toxicity studies suggest some SPAs may cause hepatic toxicity, have endocrine disrupting effects, or even be carcinogenic. The toxicity effects of some transformation products are likely worse than those of the parent compound For example, 2,6-di-tert-butyl-p-benzoquinone (BHT-Q) can cause DNA damage at low concentrations Future studies should investigate the contamination and environmental behaviors of novel high mol. weight SPAs, toxicity effects of coexposure to several SPAs, and toxicity effects on infants. Future studies should also develop novel SPAs with low toxicity and low migration ability, decreasing the potential for environmental pollution. The experimental process involved the reaction of 2,4-Di-tert-butylphenol(cas: 96-76-4).Synthetic Route of 96-76-4

The Article related to review synthetic phenolic antioxidants environmental occurrence human exposure toxicity, Air Pollution and Industrial Hygiene: Reviews and other aspects.Synthetic Route of 96-76-4

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