Tag: 100-200

New (-)-menthol-based blue phase liquid crystals with different polar substituents in the terminal group: synthesis, mesophase behaviors, and DFT calculations was written by Han, Zhi-Yuan;Kun, Shi-Qian;Kang, Jing-Tian;Jia, Ying-Gang. And the article was included in Journal of Molecular Structure in 2022.SDS of cas: 2216-51-5 This article mentions the following:

Eight novel Schiff base ester chiral liquid crystals I (R = 4-XC₆H₄; X = H, Me, F, NO₂, MeO, CN, CF₃, CF₃O), containing (-)-menthol at one end and a different polar substituent at the other end, were successfully synthesized and analyzed for their mesophase formation and stability. The combination differential scanning calorimeter (DSC), polarizing optical microscopy (POM) and X-ray diffraction (XRD) measurements were carried out to systematically study the mesomorphic properties. The photophys. properties was studied by UV-vis spectroscopy. All the prepared chiral liquid crystals, except for the compound I (R = Ph), are mesomorphic exhibiting N* and/or S_A* mesophase. The results revealed that the mesomorphic behavior and the clearing point of mesophase (T_c) correlate well with polarizability anisotropy (Δα). In the experiment, the researchers used many compounds, for example, (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5SDS of cas: 2216-51-5).

(1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.SDS of cas: 2216-51-5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Well-Defined Ni-SNS Complex Catalyzed Borrowing Hydrogenative α-Alkylation of Ketones and Dehydrogenative Synthesis of Quinolines was written by Sharma, Rahul;Mondal, Avijit;Samanta, Arup;Biswas, Nandita;Das, Babulal;Srimani, Dipankar. And the article was included in Advanced Synthesis & Catalysis in 2022.Formula: C7H7ClO This article mentions the following:

Here presented a synthesis of non-phosphine, easily accessible and bench stable SNS-Ni complexes. The Ni-catalyst was successfully applied for the C-alkylation of ketone enolates to α-alkylated ketones. Primary alc. with different functional groups and various heteroaromatic alcs. were well tolerated. The present catalyst system was efficiently applied to gram scale synthesis and also the green chem. metrics of the reaction were calculated The present protocol was also extended successfully for the synthesis of biol. important quinoline moieties. Finally, various control experiments and deuterium labeled experiments suggested that the reaction proceeds via borrowing hydrogen pathway. In the experiment, the researchers used many compounds, for example, (4-Chlorophenyl)methanol (cas: 873-76-7Formula: C7H7ClO).

(4-Chlorophenyl)methanol (cas: 873-76-7) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Formula: C7H7ClO

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Syntheses of hydrido selenophenolato iron(II) complexes and their catalytic application in hydrosilylation of aldehydes and ketones was written by Wang, Yangyang;Ren, Shishuai;Zhang, Wenbo;Xue, Benjing;Qi, Xinghao;Sun, Hongjian;Li, Xiaoyan;Fuhr, Olaf;Fenske, Dieter. And the article was included in Catalysis Communications in 2018.SDS of cas: 1777-82-8 This article mentions the following:

Three novel selenophenolato hydrido iron(II) complexes [cis-(H)(SeAr)Fe(PMe₃)₄] (Ar = C₆H₅ (I), p-MeOC₆H₄ (II) and o-MeC₆H₄ (III)) were prepared through the reaction of Fe(PMe₃)₄ with selenophenols ArSeH via Se-H activation. The iron hydrido complexes I, II and III could catalyze the hydrosilylation of aldehydes and ketones. Among them complex II is the best catalyst for this process. Furthermore, α,β-unsaturated alcs. could be obtained from the selective reduction reactions of the corresponding α,β-unsaturated carbonyls catalyzed by hydrido iron(II) complex II. This catalytic system has good tolerance for some common groups but it is easy to reduce the nitro group to an amino group. The experiments indicate that the chemoselectivity for this catalytic system is -CHO > -NO₂ > -C(:O)CH₃. The crystal structure of III was determined by X-ray diffraction. In the experiment, the researchers used many compounds, for example, (2,4-Dichlorophenyl)methanol (cas: 1777-82-8SDS of cas: 1777-82-8).

(2,4-Dichlorophenyl)methanol (cas: 1777-82-8) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.SDS of cas: 1777-82-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Reusable homogeneous metal- and additive-free photocatalyst for high-performance aerobic oxidation of alcohols to carboxylic acids was written by Cui, Jing-Wang;Ma, Shuai;Rao, Cai-Hui;Jia, Meng-Ze;Yao, Xin-Rong;Zhang, Jie. And the article was included in Applied Catalysis, B: Environmental in 2022.Recommanded Product: (4-Chlorophenyl)methanol This article mentions the following:

How to realize the recycling of homogeneous catalysts has been a great challenge for chemists. In this background, a new pyridinium compound was synthesized and applied in selective photocatalytic oxidation This photocatalytic system is advantageous in accelerating the transformation of alcs. into acids by two consecutive routes, including (1) photocatalytic oxidation of alcs. to aldehydes; (2) photocatalytic oxidation and autoxidation of aldehydes to acids. By activating mol. oxygen into ·O^-2 and ¹O₂, the system displays advantages of high efficiency and simplicity, as well as environment-friendly nature without metals or additives. Attractively, this compound as a homogeneous catalyst can be reused by direct filtration of products profiting from its high performance and stability. The present work develops a new approach to achieve an efficient and recyclable aerobic oxidation of alcs. into acids by using pyridinium-based photocatalysts and provides a valuable insight into the separation and recycling of homogeneous catalysts for economic compatibility and industrial application. In the experiment, the researchers used many compounds, for example, (4-Chlorophenyl)methanol (cas: 873-76-7Recommanded Product: (4-Chlorophenyl)methanol).

(4-Chlorophenyl)methanol (cas: 873-76-7) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Recommanded Product: (4-Chlorophenyl)methanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

The first mixed cyclooctatetraenyl-phospholyl metal complexes. Crystal structure of [U(η-C₈H₈)(η-C₄Me₄P)(BH₄)(OC₄H₈)] was written by Cendrowski-Guillaume, Sophie M.;Nierlich, Martine;Ephritikhine, Michel. And the article was included in Journal of Organometallic Chemistry in 2002.Formula: C4H9NaS This article mentions the following:

Treatment of [U(COT)(BH₄)₂(THF)] (1) or [U(COT)(BH₄)(THF)₂][BPh₄] (2) (COT = η-C₈H₈) with Ktmp (tmp = 2,3,4,5-tetramethylphospholyl) gave [U(COT)(tmp)(BH₄)(THF)] (4), the crystal structure of which was determined Further reaction of Ktmp with 4 afforded the ‘ate’ addition derivative K[U(COT)(tmp)₂(BH₄)(THF)_x]. Complex 4 was transformed into [U(COT)(tmp)(OEt)] (5) in the presence of NaOEt. The cationic compound [U(COT)(tmp)(HMPA)₂][BPh₄] (6) (HMPA, hexamethylphosphoramide) was isolated from the reaction of [U(COT)(HMPA)₃][BPh₄]₂ (3) with Ktmp. The cationic complexes 2 and 3 were recovered upon protonation of 4 and 6 with NEt₃HBPh₄. In the experiment, the researchers used many compounds, for example, Sodium 2-methyl-2-propanethiolate (cas: 29364-29-2Formula: C4H9NaS).

Sodium 2-methyl-2-propanethiolate (cas: 29364-29-2) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Formula: C4H9NaS

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Prospecting of essential oils in combination with florfenicol against motile Aeromonas isolated from tambaqui (Colossoma macropomum) was written by da Silva, Ana Maria Souza;Chagas, Edsandra Campos;Chaves, Francisco Celio Maia;de Alexandre Sebastiao, Fernanda. And the article was included in Archives of Microbiology in 2022.Synthetic Route of C10H14O This article mentions the following:

Natural products with antimicrobial activity and their association with synthetic antimicrobials are a sustainable option in fish farming. The objective of this study was to determine antimicrobial activity, antibiofilm potential and synergism of five essential oils (EOs) with florfenicol against motile Aeromonas isolated from Amazonian Colossoma macropomum. As their major constituent, the EOs of the species of Aloysia triphylla, Croton cajucara (red and white morphotype), Cymbopongo citratus and Lippia gracilis present β-pinene (22.1%), germacrene D (11.5%), linalool (23%), geranial (45.7%) and carvacrol (42.2%), resp. The EOs of L. gracilis and C. citratus showed the best antimicrobial activities against the Aeromonas strains (5 mg mL-1). All EOs interfered with biofilm formation and consolidated biofilm. The EOs of A. triphylla, C. citratus and L. gracilis showed a synergistic effect with florfenicol, reducing the amount of the chem. into the water systems while treatment. In the experiment, the researchers used many compounds, for example, 5-Isopropyl-2-methylphenol (cas: 499-75-2Synthetic Route of C10H14O).

5-Isopropyl-2-methylphenol (cas: 499-75-2) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Synthetic Route of C10H14O

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

One-pot fermentation for erythritol production from distillers grains by the co-cultivation of Yarrowia lipolytica and Trichoderma reesei was written by Liu, Xiaoyan;Yu, Xinjun;He, Aiyong;Xia, Jun;He, Jianlong;Deng, Yuanfang;Xu, Ning;Qiu, Zhongyang;Wang, Xiaoyu;Zhao, Pusu. And the article was included in Bioresource Technology in 2022.COA of Formula: C4H10O4 This article mentions the following:

A co-fermentation process involving Yarrowia lipolytica and Trichoderma reesei was studied, using distillers grains (DGS) as feedstocks for erythritol production DGS can be effectively hydrolyzed by cellulase in the single-strain culture of T. reesei. One-pot solid state fermentation for erythritol production was then established by co-cultivating Y. lipolytica M53-S with the 12 h delay inoculated T. reesei Rut C-30, in which efficient saccharification of DGS and improved production of erythritol were simultaneously achieved. The 10:1 inoculation proportion of Y. lipolytica and T. reesei contributed to the maximum erythritol production of 267.1 mg/gds under the optimal conditions including initial moisture of 55%, pH of 5.0, NaCl addition of 0.02 g/gds and DGS mass of 200 g in 144 h co-cultivation. Being compared with the attempts to produce erythritol from other raw materials, the one-pot SSF with DGS is proposed to be a potential strategy for efficient and economical erythritol production In the experiment, the researchers used many compounds, for example, (2R,3S)-rel-Butane-1,2,3,4-tetraol (cas: 149-32-6COA of Formula: C4H10O4).

(2R,3S)-rel-Butane-1,2,3,4-tetraol (cas: 149-32-6) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.COA of Formula: C4H10O4

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Thiolate-bridged dinuclear iron(tris-carbonyl)-nickel complexes relevant to the active site of [NiFe] hydrogenase was written by Ohki, Yasuhiro;Yasumura, Kazunari;Kuge, Katsuaki;Tanino, Soichiro;Ando, Masaru;Li, Zilong;Tatsumi, Kazuyuki. And the article was included in Proceedings of the National Academy of Sciences of the United States of America in 2008.Related Products of 29364-29-2 This article mentions the following:

The reaction of NiBr₂(EtOH)₄ with 1:2-3 mixture of FeBr₂(CO)₄ and Na(SPh) generated a linear trinuclear Fe-Ni-Fe cluster (CO)₃Fe(μ-SPh)₃Ni(μ-SPh)₃Fe(CO)₃, 1, whereas the analogous reaction system FeBr₂(CO)₄/Na(S^tBu)/NiBr₂(EtOH)₄ (1:2-3:1) gave rise to a linear tetranuclear Fe-Ni-Ni-Fe cluster [(CO)₃Fe(μ-S^tBu)₃Ni(μ-Br)]₂, 2. By using this tetranuclear cluster 2 as the precursor, we have developed a new synthetic route to a series of thiolate-bridged dinuclear Fe(CO)₃-Ni complexes, the structures of which mimic [NiFe] hydrogenase active sites. The reactions of 2 with SC(NMe₂)₂ (tmtu), Na{S(CH₂)₂SMe} and ortho-NaS(C₆H₄)SR (R = Me, ^tBu) led to isolation of (CO)₃Fe(μ-S^tBu)₃NiBr(tmtu), 3, (CO)₃Fe(S^tBu)(μ-S^tBu)₂NI{S(CH₂)₂SMe}, 4, and (CO)₃Fe(S^tBu)(μ-S^tBu)₂Ni{S(C₆H₄)SR}, 5a (R = Me) and 5b (R = ^tBu), resp. Treatment of 2 with 2-methylthiophenolate (ortho-O(C₆H₄)SMe) in methanol resulted in (CO)₃Fe(μ-S^tBu)₃Ni(MeOH){O(C₆H₄)SMe}, 6a. The methanol mol. bound to Ni is labile and is readily released under reduced pressure to afford (CO)₃Fe(S^tBu)(μ-S^tBu)₂Ni{O(C₆H₄)SMe}, 6b, and the coordination geometry of nickel changes from octahedral to square planar. Likewise, the reaction of 2 with NaOAc in methanol followed by crystallization from THF gave (CO)₃Fe(μ-S^tBu)₃Ni(THF)(OAc), 7. The dinuclear complexes, 3-7, are thermally unstable, and a key to their successful isolation is to carry out the reactions and manipulations at -40°. In the experiment, the researchers used many compounds, for example, Sodium 2-methyl-2-propanethiolate (cas: 29364-29-2Related Products of 29364-29-2).

Sodium 2-methyl-2-propanethiolate (cas: 29364-29-2) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Related Products of 29364-29-2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Enantioselective synthesis of diisopropyl α-, β-, and γ-hydroxyarylalkylphosphonates from ketophosphonates: a study on the effect of the phosphonyl group was written by Meier, Chris;Laux, Wolfgang H. G.. And the article was included in Tetrahedron in 1996.Electric Literature of C8H9FO This article mentions the following:

A comparative study of different reduction conditions to an enantioselective synthesis of diisorpropyl α-, β- and γ-hydroxyphosphonates by 1,3,2-oxaborolidine catalysis using catecholborane or BH₃·Me₂S is described. The comparison to acetophenone reductions gave information’s on the effect of the phosphonyl group during the reduction of ketophosphonate. So very efficient syntheses to chiral dialkyl α-, β- and γ-hydroxyphosphonates were elaborated. In the experiment, the researchers used many compounds, for example, (S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4Electric Literature of C8H9FO).

(S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Electric Literature of C8H9FO

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Synthesis of 1,3-Dicarbonyl Compounds using N-Cbz Amides as an Acyl Source under Transition-metal-free Conditions at Room Temperature was written by Singh, Shweta;Kandasamy, Jeyakumar. And the article was included in Asian Journal of Organic Chemistry in 2022.Synthetic Route of C10H20O This article mentions the following:

A wide range of functionalized N-Cbz amides underwent base-promoted C-C coupling reactions with enolizable esters, ketones and amides to afford 1,3-dicarbonyl compounds under mild conditions. The reactions proceeded at room temperature in the presence of LiHMDS in cyclopentyl Me ether (CPME). The desired β-ketoesters, β-keto amides and 1,3-diketones were obtained in good to excellent yields in a short reaction time. Broad substrate scope, functional group tolerance and metal-free conditions are the merits of the developed methodol. In the experiment, the researchers used many compounds, for example, (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5Synthetic Route of C10H20O).

(1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Synthetic Route of C10H20O

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts