Tag: 100-200

Single particle measurements of mixing between mimics for biomass burning and aged secondary organic aerosols was written by Habib, Luke;Donahue, Neil. And the article was included in Environmental Science: Atmospheres in 2022.Recommanded Product: 149-32-6 This article mentions the following:

Gas-phase exchange between aerosol populations via evaporation and condensation of semi-volatile organics can be a major mechanism of mixing between accumulation-mode particles with slow coagulation. This exchange may be impeded in highly viscous, semi-solid, or glassy particles due to diffusion limitations. Here we describe experiments on carefully prepared particle populations representing highly viscous or potentially “glassy” aged organic particles (non-volatile sugars 13C-glucose, sucrose, and raffinose with ammonium sulfate seeds) and fresh biomass burning particles (erythritol with black carbon seeds) to develop a model phase space for organic aerosol systems and better understand when particle phase state impedes mixing. Our hypothesis is that these limitations are alleviated at some relative humidity threshold, which increases with decreasing ambient temperatures We quantify the mixing state of these particle populations from 10-25°C and 5-90% RH using an Aerosol Mass Spectrometer (AMS) combining Event Trigger (ET) and Soot Particle (SP) modes. The observed single particle mass spectra are aggregated in short time slices and used to perform a linear combination of relevant reference spectra to determine the contributions each constituent has on the resulting particle signal. Our results suggest that the non-volatile sugar particles have little to no diffusive limitations to mixing at the conditions tested. In the experiment, the researchers used many compounds, for example, (2R,3S)-rel-Butane-1,2,3,4-tetraol (cas: 149-32-6Recommanded Product: 149-32-6).

(2R,3S)-rel-Butane-1,2,3,4-tetraol (cas: 149-32-6) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Recommanded Product: 149-32-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Catalytic Asymmetric β-Oxygen Elimination was written by Matt, Christof;Orthaber, Andreas;Streuff, Jan. And the article was included in Angewandte Chemie, International Edition in 2022.SDS of cas: 2216-51-5 This article mentions the following:

A catalytic enantioselective β-O-elimination reaction is reported in the form of a zirconium-catalyzed asym. opening of meso-ketene acetals. Furthermore, a regiodivergent β-O-elimination is demonstrated. The reaction proceeds under mild conditions, at low catalyst loadings, and produces chiral monoprotected cis-1,2-diols in good yield and enantiomeric excess. The combination with a Mitsunobu reaction or a one-pot hydroboration/Suzuki reaction sequence then gives access to addnl. diol and aminoalc. building blocks. A stereochem. anal. supported by DFT calculations reveals that a high selectivity in the hydrozirconation step is also important for achieving high enantioselectivity, although it does not constitute the asym. step. This insight is crucial for the future development of related asym. β-elimination reactions. In the experiment, the researchers used many compounds, for example, (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5SDS of cas: 2216-51-5).

(1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.SDS of cas: 2216-51-5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Visible Light-Induced Hydrosilylation of Electron-Deficient Alkenes by Iron Catalysis was written by Ding, Ling;Niu, Kaikai;Liu, Yuxiu;Wang, Qingmin. And the article was included in ChemSusChem in 2022.SDS of cas: 2216-51-5 This article mentions the following:

Regioselective photochem. hydrosilylation of activated alkenes R¹CH:CR²(EWG) with Ph₃SiH catalyzed by iron trichloride, afforded linear triphenylsilanes Ph₃SiCHR¹CHR²(EWG) (R¹, R² = H, Me, CF₃, CO₂Me; EWG = carboxylate, CN, CHO, CONHPh). Herein, we reported a method for iron-catalyzed, visible-light-induced hydrosilylation reactions of electron-deficient alkenes to produce value-added silicon compounds Alkenes bearing functional groups with different steric properties were suitable substrates, as were derivatives of structurally complex natural products. Mechanistic studies showed that chlorine radicals generated by iron-catalyzed ligand-to-metal charge transfer in the presence of lithium chloride promoted the formation of silyl radicals. In the experiment, the researchers used many compounds, for example, (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5SDS of cas: 2216-51-5).

(1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.SDS of cas: 2216-51-5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Nanoscale Assembly of CdS/BiVO₄ Hybrids for Coupling Selective Fine Chemical Synthesis and Hydrogen Production under Visible Light was written by Shang, Feng-Kang;Qi, Ming-Yu;Tan, Chang-Long;Tang, Zi-Rong;Xu, Yi-Jun. And the article was included in ACS Physical Chemistry Au in 2022.Product Details of 873-76-7 This article mentions the following:

Simultaneously utilizing photogenerated electrons and holes in one photocatalytic system to synthesize value-added chems. and clean hydrogen (H₂) energy meets the development requirements of green chem. Herein, we report a binary material of CdS/BiVO₄ combining one-dimensional (1D) CdS nanorods (NRs) with two-dimensional (2D) BiVO₄ nanosheets (NSs) constructed through a facile electrostatic self-assembly procedure for the selectively photocatalytic oxidation of aromatic alcs. integrated with H₂ production, which exhibits significantly enhanced photocatalytic performance. Within 2 h, the conversion of aromatic alcs. over CdS/BiVO₄-25 was approx. 9-fold and 40-fold higher than that over pure CdS and BiVO₄, resp. The remarkably improved photoactivity of CdS/BiVO₄ hybrids is mainly ascribed to the Z-scheme charge separation mechanism in the 1D/2D heterostructure derived from the interface contact between CdS and BiVO₄, which not only facilitates the separation and transfer of charge carriers, but also maintains the strong reducibility of photogenerated electrons and strong oxidizability of photogenerated holes. It is anticipated that this work will further stimulate interest in the rational design of 1D/2D Z-scheme heterostructure photocatalysts for the selective fine chem. synthesis integrated with H₂ evolution. In the experiment, the researchers used many compounds, for example, (4-Chlorophenyl)methanol (cas: 873-76-7Product Details of 873-76-7).

(4-Chlorophenyl)methanol (cas: 873-76-7) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Product Details of 873-76-7

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Liquid-crystal compounds. VIII. Methyl-substituted p-alkyl- and p-alkoxycinnamic acids and their cyanophenyl esters was written by Pavlyuchenko, A. I.;Smirnova, N. I.;Kovshev, E. I.;Titov, V. V.. And the article was included in Zhurnal Organicheskoi Khimii in 1976.SDS of cas: 15777-70-5 This article mentions the following:

P-RC6H4CH:CMeCO2H (I; R = Bu, pentyl, hexyl) were prepared in 18.4-21.1% yield by reaction of RC6H4CHO with MeCHBrCO2Et followed by hydrolysis; their p-cyanophenyl esters were prepared by standard procedures. The p-RC6H4CMe:CHCO2H (II; R = Bu, pentyl, hexyl, heptyl, octyl) were prepared in 20.1-25.0% yield by condensation of p-RC6H4COMe with HOAc; their p-cyanophenyl esters were also prepared Six III (R = Bu, heptyl; R1 = 2- and 3-Me, H; R2 = 2- and 3-Me, H) were also prepared by standard methods. In I, II, and III the temperature of clearing was lowered and the mesomorphic interval narrowed with respect to the unsubstituted compounds II have a wider mesomorphic range than p-alkylcinnamic acids. In the experiment, the researchers used many compounds, for example, 4-Hydroxy-3-methylbenzonitrile (cas: 15777-70-5SDS of cas: 15777-70-5).

4-Hydroxy-3-methylbenzonitrile (cas: 15777-70-5) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.SDS of cas: 15777-70-5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

O₂-Assisted Four-Component Reaction of Vinyl Magnesium Bromide with Chiral N-tert-Butanesulfinyl Imines To Form syn-1,3-Amino Alcohols was written by Wang, Runping;Luo, Jingfan;Zheng, Chunmei;Zhang, Hongyun;Gao, Lu;Song, Zhenlei. And the article was included in Angewandte Chemie, International Edition in 2021.Name: 1-Boc-Azetidine-3-yl-methanol This article mentions the following:

An O₂-assisted, four-component reaction has been developed to synthesize a wide range of syn-1,3-amino alcs. in one step. The reaction proceeds by oxygenation of vinyl magnesium bromide (component-I) with O₂ (component-II) to give a magnesium enolate of acetaldehyde, which undergoes addition to a chiral N-tert-butanesulfinyl imine (component-III) followed by a sequential addition with excess vinyl magnesium bromide (component-IV). The approach allows diastereoselective synthesis of anti/syn- and syn/syn-3-amino-1,5-diols in good yields with high diastereoselectivity. The method was illustrated in an efficient, four-step synthesis of piperidine alkaloid (-)-2′-epi-ethylnorlobelol. In the experiment, the researchers used many compounds, for example, 1-Boc-Azetidine-3-yl-methanol (cas: 142253-56-3Name: 1-Boc-Azetidine-3-yl-methanol).

1-Boc-Azetidine-3-yl-methanol (cas: 142253-56-3) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Name: 1-Boc-Azetidine-3-yl-methanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Design, Synthesis, and Structure-Activity Relationship Studies of a Series of [4-(4-Carboxamidobutyl)]-1-arylpiperazines: Insights into Structural Features Contributing to Dopamine D3 versus D2 Receptor Subtype Selectivity was written by Ananthan, Subramaniam;Saini, Surendra K.;Zhou, Guangyan;Hobrath, Judith V.;Padmalayam, Indira;Zhai, Ling;Bostwick, J. Robert;Antonio, Tamara;Reith, Maarten E. A.;McDowell, Shea;Cho, Eunie;McAleer, Leah;Taylor, Michelle;Luedtke, Robert R.. And the article was included in Journal of Medicinal Chemistry in 2014.Related Products of 79651-64-2 This article mentions the following:

(Aroylaminobutyl)arylpiperazines such as I were prepared as antagonists or partial agonists of the dopamine D3 receptor selective for D3 receptors over the related dopamine D2 receptors for potential use in treatment of drug addiction and schizophrenia. The calculated lipophilicities of and inhibition of dopamine D3 and D2 receptors by (aroylaminobutyl)arylpiperazines was determined, and the inhibition of mutant and chimeric D3 receptors by selected compounds and the activities of selected compounds in functional assays in human cells were determined Mol. docking calculations of the structures of selected compounds bound to dopamine D3 receptors were performed; the mol. docking studies and evaluation against a set of chimeric and mutant receptors suggest that interactions at the extracellular end of TM7 contribute to the selectivity of the ligands for dopamine D3 receptors over dopamine D2 receptors. In the experiment, the researchers used many compounds, for example, (6-Aminopyridin-2-yl)methanol (cas: 79651-64-2Related Products of 79651-64-2).

(6-Aminopyridin-2-yl)methanol (cas: 79651-64-2) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Related Products of 79651-64-2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Discrimination and Characterization of the Volatile Organic Compounds in Schizonepetae Spica from Six Regions of China Using HS-GC-IMS and HS-SPME-GC-MS was written by Li, Chao;Wan, Huiying;Wu, Xinlong;Yin, Jiaxin;Zhu, Limin;Chen, Hanjiang;Song, Xinbo;Han, Lifeng;Yang, Wenzhi;Yu, Heshui;Li, Zheng. And the article was included in Molecules in 2022.Quality Control of (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol This article mentions the following:

Volatile organic compounds (VOCs) are the main chem. components of Schizonepetae Spica (SS), which have pos. effects on the quality evaluation of SS. In this study, HS-SPME-GC-MS (headspace solid-phase microextraction-gas chromatog.-mass spectrometry) and HS-GC-IMS (headspace-gas chromatog.-ion mobility spectrometry) were performed to characterize the VOCs of SS from six different regions. A total of 82 VOCs were identified. In addition, this work compared the suitability of two instruments to distinguish SS from different habitats. The regional classification using orthogonal partial least squares discriminant anal. (OPLS-DA) shows that the HS-GC-IMS method can classify samples better than the HS-SPME-GC-MS. This study provided a reference method for identification of the SS from different origins. In the experiment, the researchers used many compounds, for example, (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5Quality Control of (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol).

(1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Quality Control of (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Synthesis, Antifungal Activity, and 3D-QASR of Novel 1,2,3,4-Tetrahydroquinoline Derivatives Containing a Pyrimidine Ether Scaffold as Chitin Synthase Inhibitors was written by Zhang, Xiaoming;Yang, Zhaokai;Xu, Huan;Liu, Yuansheng;Yang, Xinling;Sun, Tengda;Lu, Xingxing;Shi, Fasheng;Yang, Qing;Chen, Wei;Duan, Hongxia;Ling, Yun. And the article was included in Journal of Agricultural and Food Chemistry in 2022.Application of 499-75-2 This article mentions the following:

The introduction of active groups of natural products into the framework of pesticide mols. is an effective approach for discovering active lead compounds, and thus has been widely used in the development of new agrochems. In this work, a novel series of 1,2,3,4-tetrahydroquinoline derivatives containing a pyrimidine ether scaffold were designed and synthesized by the active substructure splicing method. The new compounds showed good antifungal activities against several fungi. Especially, compound (I) displayed excellent in vitro activity against Valsa mali and Sclerotinia sclerotiorum with EC₅₀ values of 0.71 and 2.47 μg/mL, resp. I had slightly stronger inhibitory activity (68.08% at 50 μM) against chitin synthase (CHS) than that of polyoxin D (63.84% at 50 μM) and exhibited obvious curative and protective effects on S. sclerotiorumin vivo. Thus, I can be considered as a new candidate fungicide as a chitin synthase inhibitor. An accurate and reliable three-dimensional quant. structure-activity relationship (3D-QSAR) model presented a useful direction for the further excogitation of more highly active fungicides. Mol. docking revealed that the conventional hydrogen bond mainly affected the binding affinity of I with chitin synthase. The present results will provide a guidance to discover potential CHS-based fungicides for plant disease control in agriculture. In the experiment, the researchers used many compounds, for example, 5-Isopropyl-2-methylphenol (cas: 499-75-2Application of 499-75-2).

5-Isopropyl-2-methylphenol (cas: 499-75-2) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Application of 499-75-2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Eco-friendly mechanochemical preparation of Ag2O-MnO2/graphene oxide nanocomposite: an efficient and reusable yst for the base-free, aerial oxidation of alcohols was written by Adil, Syed Farooq;Assal, Mohamed E.;Khan, Mujeeb;Shaik, Mohammed Rafi;Kuniyil, Mufsir;Sekou, Doumbia;Dewidar, Ahmed Z.;Al-Warthan, Abdulrahman;Siddiqui, Mohammed Rafiq H.. And the article was included in Catalysts in 2020.Reference of 1777-82-8 This article mentions the following:

Recently, the development of eco-friendly mechanochem. approaches for the preparation of novel ysts with enhanced activity and selectivity has gained considerable attention. Herein, we developed a rapid and solvent-less mechanochem. method for the preparation of mixed metal oxide (Ag₂O-MnO₂) decorated graphene oxide (GRO)-based nanocomposites (Ag₂O-MnO₂/(X weight%)GRO), as the Ag₂O-MnO₂/(X weight%)GRO nanocomposite was fabricated by the phys. grinding of freshly prepared GRO and pre-annealed (300°C) mixed metal oxide nanoparticles (NPs) (Ag2O-MnO2) using an eco-friendly milling procedure. The as-prepared nanoysts were characterized by using various techniques. Furthermore, the nanocomposites were applied as a heterogeneous yst for the oxidation of alc. by employing gaseous O₂ as an eco-friendly oxidant under base-free conditions. The mechanochem. obtained GRO-based composite exhibited noticeable enhancement in the surface area and ytic performance compared to the pristine Ag₂O-MnO₂. The results revealed that (1%)Ag₂O-MnO₂/(5 weight%)GRO yst exhibited higher specific performance (13.3 mmol.g^-1.h^-1) with a 100% conversion of benzyl alc. (BnOH) and >99% selectivity towards benzaldehyde (BnH) within 30 min. The enhancement of the activity and selectivity of GRO-based nanoyst was attributed to the presence of various oxygen-containing functional groups, a large number of defects, and a high sp. surface area of GRO. In addition, the as-prepared nanoyst also demonstrated excellent ytic activity towards the conversion of a variety of other alcs. to resp. carbonyls under optimal conditions. Besides, the yst ((1%)Ag₂O-MnO₂/(5 weight%)GRO) could be efficiently recycled six times with no noticeable loss in its performance and selectivity. In the experiment, the researchers used many compounds, for example, (2,4-Dichlorophenyl)methanol (cas: 1777-82-8Reference of 1777-82-8).

(2,4-Dichlorophenyl)methanol (cas: 1777-82-8) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Reference of 1777-82-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts