Tag: 100-200

Liu, E. published 《Design, synthesis and activities of novel tamibarotene analogues containing nitrogen heterocyclic ring》 in 2014. The article was appeared in 《Zhongguo Xinyao Zazhi》. They have made some progress in their research.Recommanded Product: 2,5-Dimethyl-2,5-hexanediol The article mentions the following:

Three novel tamibarotene analogs containing nitrogen heterocyclic ring were designed, synthesized and evaluated. Target compounds were synthesized through 8 steps using 2,5-dimethyl-2,5-hexanediol and di-Et oxalate as starting materials. In vitro antitumor bioactivities against HL-60 cells and NB4 cells were evaluated by a MTT assay method. Their structures were identified by ¹H-NMR, MS and elemental anal. Three compounds had inhibitory effects on HL-60 cells and NB4 cells. To complete the study, the researchers used 2,5-Dimethyl-2,5-hexanediol (cas: 110-03-2) .

2,5-Dimethyl-2,5-hexanediol(cas:110-03-2) is used as an intermediate in the preparation of 2.5-Dimethyl-2.5-bis(tertbutyl-peroxy)hexane. It is also used in the synthesis of six- and seven-membered heterocyclic boron compounds.Recommanded Product: 2,5-Dimethyl-2,5-hexanediol

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Related Products of 78-69-3《Comparison of the odorant composition of post-consumer high-density polyethylene waste with corresponding recycled and virgin pellets by combined instrumental and sensory analysis》 was published in 2018. The authors were Strangl, Miriam;Schlummer, Martin;Maeurer, Andreas;Buettner, Andrea, and the article was included in《Journal of Cleaner Production》. The author mentioned the following in the article:

Both, for ecol. and economic reasons, the recycling of plastics for new or broader applications is currently gaining more and more attention. As high-d. polyethylene (HDPE) plays an essential role in various packaging, the recycling of this material is particularly sought for. Thereby, odorous contaminants are a common obstacle when aiming at achieving high-quality HDPE recycled goods. In this respect, revealing the differences in the odorant composition of waste, recycled pellets and virgin pellets provides insights into odor sources and formation pathways and therefore supports the developing of optimized avoidance strategies. For this reason, the odor of post-consumer HDPE waste, corresponding recycled HDPE pellets and virgin HDPE granules was analyzed in the frame of the present study by comprehensive sensory anal. as well as instrumental anal. using high resolution gas chromatog.-olfactometry followed by two-dimensional high resolution gas chromatog.-mass spectrometry-olfactometry. In total, 32 odorous substances were identified. While some oxidation products were present in all three samples, albeit mostly with much higher smell intensity when regarding the waste and the recycled pellets, a number of terpenes as well as phenylpropanoids were found only in the HDPE waste and recycled material and, in most cases, with high sensory abundance. These odorants are likely to stem from fragrances used in cosmetics and washing/cleaning agents. Moreover, comparative odor extract dilution anal. (cOEDA) revealed that the applied conventional recycling process resulted only in a slight reduction of the odor pollution; moreover, it could be shown that no new odorants were generated to any relevant extent. Accordingly, this study shows that further optimized strategies for odorant removal from post-consumer recycled HDPE material are required. The experimental procedure involved many compounds, such as 3,7-Dimethyloctan-3-ol (cas: 78-69-3) .

3,7-Dimethyloctan-3-ol(cas:78-69-3) is a fatty alcohol that is 3-octanol substituted by methyl groups at positions 3 and 7.Related Products of 78-69-3 Metabolite observed in cancer metabolism. It has a role as a human metabolite.

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Category: alcohols-buliding-blocks《A star-shaped solid composite electrolyte containing multifunctional moieties with enhanced electrochemical properties for all solid-state lithium batteries》 was published in 2018. The authors were Zhang, Jinfang;Ma, Cheng;Hou, Hua;Li, Xiaofeng;Chen, Libao;Ivey, Douglas G.;Wei, Weifeng, and the article was included in《Journal of Membrane Science》. The author mentioned the following in the article:

Limited ionic conduction and poor solid/solid interfacial stability are crucial characteristics that impede the practical application of solid polymeric electrolytes. Herein, a star-shaped solid composite electrolyte (SCE) containing multifunctional components, including anion-trapping boron moieties (B-PEGMA), poly(ethylene glycol)methyl ether methacrylate (PEGMEM) and octavinyl octasilsesquioxane (OV-POSS) nanofiller, was developed via a simple free radical polymerization method. The unique star-shaped structure induced by OV-POSS is beneficial to increasing the movement of polymer chains and forming continuously interconnected ion-conducting channels and the boron moieties can promote lithium salt dissociation and increase the effective transmission of Li⁺ in the electrolyte. This SCE exhibits an extremely high ionic conductivity of 3.44 × 10^-4 S cm^-1 and a high Li ion transference number of 0.58 at 25°C, as well as excellent interfacial compatibility with the Li electrode leading to excellent rate performance and good cyclic stability in all-solid-state Li batteries. To complete the study, the researchers used 2,5-Dimethyl-2,5-hexanediol (cas: 110-03-2) .

2,5-Dimethyl-2,5-hexanediol(cas:110-03-2) is used as an intermediate in the preparation of 2.5-Dimethyl-2.5-bis(tertbutyl-peroxy)hexane. It is also used in the synthesis of six- and seven-membered heterocyclic boron compounds.Category: alcohols-buliding-blocks

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Liebold, Martin;Sharikow, Eugen;Seikel, Elisabeth;Trombach, Lukas;Harms, Klaus;Zimcik, Petr;Novakova, Veronika;Tonner, Ralf;Sundermeyer, Joerg published 《An experimental and computational study on isomerically pure, soluble azaphthalocyanines and their complexes and boron azasubphthalocyanines of a varying number of aza units》 in 2018. The article was appeared in 《Organic & Biomolecular Chemistry》. They have made some progress in their research.Related Products of 110-03-2 The article mentions the following:

Herein, the authors present a series of isomerically pure, peripherally alkyl substituted, soluble and low aggregating azaphthalocyanines as well as their new, smaller hybrid homologs, azasubphthalocyanines. The focus lies on the effect of the systematically increasing number of aza building blocks [-N=] replacing the non-peripheral [-CH=] units and their influence on the phys. and photophys. properties of these chromophores. The absolute and relative HOMO-LUMO energies of azaphthalocyanines were analyzed using UV-visible and CV and compared to the d. functional theory calculations (B3LYP, TD-DFT). The lowering of the HOMO level is revealed as the determining factor for the trend in the adsorption energies by electronic structure anal. Crystals of substituted subphthalocyanines, N₂-Pc*H₂ and N₄-[Pc*Zn·H₂O], were obtained out of DCM. For the synthesis of the valuable tetramethyltetralin phthalocyanine building block a new highly efficient synthesis involving a nearly quant. Co^II catalyzed aerobic autoxidation step is introduced replacing inefficient KMnO₄/pyridine as the oxidant. And 2,5-Dimethyl-2,5-hexanediol (cas: 110-03-2) was used in the research process.

2,5-Dimethyl-2,5-hexanediol(cas:110-03-2) is used as an intermediate in the preparation of 2.5-Dimethyl-2.5-bis(tertbutyl-peroxy)hexane. It is also used in the synthesis of six- and seven-membered heterocyclic boron compounds.Related Products of 110-03-2

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Electric Literature of C11H16OIn 2019, Zhang, Zhen;Ruan, Zhiyong;Liu, Jin;Liu, Chang;Zhang, Fuming;Linhardt, Robert J.;Li, Lin published 《Complete degradation of bisphenol A and nonylphenol by a composite of biogenic manganese oxides and Escherichia coli cells with surface-displayed multicopper oxidase CotA》. 《Chemical Engineering Journal (Amsterdam, Netherlands)》published the findings. The article contains the following contents:

Endocrine-disrupting chems. (EDCs) are a large group of environmental toxicants that pose serious risks to public health. In this study, we report a new method for the complete degradation of EDCs using a dual oxidation-action composite of biogenic manganese oxides and engineered Escherichia coli cells with surface-expressed multicopper oxidase CotA. The cotA gene from a Mn²⁺-oxidizing bacterium was constructed as a fusion gene “inaQ-N/cotA” with an anchoring motif inaQ-N from Pseudomonas syringae and was expressed in E. coli cells to display catalytic CotA on the cell surface. Under prolonged Mn²⁺-enriched culturing conditions, the engineered cells were capable of forming microspherical aggregated composites that were mainly composed of ramsdellite (MnO₂). The ability of the composite to degrade two EDCs, bisphenol A (BPA) and nonylphenol (NP), was investigated. GC-MS assays identified 7 and 10 degraded intermediates using the ¹³C isotope from ¹³C-labeled BPA and ¹³C-labeled NP, resp. The appearance of ¹³CO₂ from both reaction mixtures revealed mineralization pathways of BPA and NP by this composite. Bioassays using Caenorhabditis elegans as an indicator organism demonstrated that the estrogenic activity of BPA and NP was eliminated by these degradation processes. The reaction of the composite proceeded at an acidic pH and room temperature A consecutive three-round treatment process showed comparable levels of degradation by the composite in repeated reactions and showed that the activity could be easily recovered. Moreover, the superoxide radical levels of BPA-degradation and NP-degradation were monitored during the 24 h reaction time, and possible BPA-degradation and NP-degradation pathways by the composite were proposed. The experimental procedure involved many compounds, such as 4-tert-Amylphenol (cas: 80-46-6) .

4-tert-acylphenol (cas:80-46-6) contains hydroxyl group. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Electric Literature of C11H16O

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Lewandowski, Andrzej;Szymczyk, Katarzyna published 《Adsorption of monoterpene alcohols at the water-air interface》 in 2019. The article was appeared in 《Adsorption》. They have made some progress in their research.HPLC of Formula: 78-69-3 The article mentions the following:

The measurements of the surface tension of aqueous solutions of 10 monoterpene alcs., MAs: (-)-β-citronellol, geraniol, tetrahydrolinalool, linalool, (-)-menthol, (-)-terpinen-4-ol, p-cymene-8-ol, α-terpineol, isoborneol and (-)-borneol were made at T = 293 K. On the basis of the obtained results the values of the adsorption constant, the excluded area per mol. at the interface and the interaction parameter were determined by fitting the exptl. data to various adsorption models. Next the adsorption free energy of studied MAs was determined and discussed in terms of the preferred orientation of studied MAs at the water-air interface and mol. structure of MAs. The experimental procedure involved many compounds, such as 3,7-Dimethyloctan-3-ol (cas: 78-69-3) .

3,7-Dimethyloctan-3-ol(cas:78-69-3) is a fatty alcohol that is 3-octanol substituted by methyl groups at positions 3 and 7.HPLC of Formula: 78-69-3 Metabolite observed in cancer metabolism. It has a role as a human metabolite.

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Alcohol – Wikipedia,
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HPLC of Formula: 80-46-6In 2016, Kluever, Nils;Vogs, Carolina;Altenburger, Rolf;Escher, Beate I.;Scholz, Stefan published 《Development of a general baseline toxicity QSAR model for the fish embryo acute toxicity test》. 《Chemosphere》published the findings. The article contains the following contents:

Fish embryos have become a popular model in ecotoxicol. and toxicol. The fish embryo acute toxicity test (FET) with the zebrafish embryo was recently adopted by the OECD as tech. guideline TG 236 and a large database of concentrations causing 50% lethality (LC₅₀) is available in the literature. Quant. Structure-Activity Relationships (QSARs) of baseline toxicity (also called narcosis) are helpful to estimate the min. toxicity of chems. to be tested and to identify excess toxicity in existing data sets. Here, we analyzed an existing fish embryo toxicity database and established a QSAR for fish embryo LC₅₀ using chems. that were independently classified to act according to the non-specific mode of action of baseline toxicity. The octanol-water partition coefficient K_ow is commonly applied to discriminate between non-polar and polar narcotics. Replacing the K_ow by the liposome-water partition coefficient K_lipw yielded a common QSAR for polar and non-polar baseline toxicants. This developed baseline toxicity QSAR was applied to compare the final mode of action (MOA) assignment of 132 chems. Further, we included the anal. of internal lethal concentration (ILC₅₀) and chem. activity (La₅₀) as complementary approaches to evaluate the robustness of the FET baseline toxicity. The anal. of the FET dataset revealed that specifically acting and reactive chems. converged towards the baseline toxicity QSAR with increasing hydrophobicity. The developed FET baseline toxicity QSAR can be used to identify specifically acting or reactive compounds by determination of the toxic ratio and in combination with appropriate endpoints to infer the MOA for chems. The experimental procedure involved many compounds, such as 4-tert-Amylphenol (cas: 80-46-6) .

4-tert-acylphenol (cas:80-46-6) contains hydroxyl group.Some low molecular weight alcohols of industrial importance are produced by the addition of water to alkenes. Ethanol, isopropanol, 2-butanol, and tert-butanol are produced by this general method. HPLC of Formula: 80-46-6

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Land, Michael A.;Bacic, Goran;Robertson, Katherine N.;Barry, Sean T. published 《Thermal Stability and Decomposition Pathways in Volatile Molybdenum(VI) Bis-imides》 in 2022. The article was appeared in 《Inorganic Chemistry》. They have made some progress in their research.Electric Literature of C8H18O2 The article mentions the following:

The vapor deposition of many Mo-containing films relies on the delivery of volatile compounds with the general bis(tert-butylimido)molybdenum(VI) framework, both in at. layer deposition and CVD. The authors prepared (^tBuN)₂MoCl₂ adducts using neutral N,N’-chelates and studied their volatility, thermal stability, and decomposition pathways. Volatility was determined by TGA, with the 1,4-di-tert-butyl-1,3-diazabutadiene adduct (5) found to be the most volatile (1 torr of vapor pressure at 135°). Thermal stability was measured primarily using DSC, and the 1,10-phenanthroline adduct (4) is the most stable with an onset of decomposition of 303°. The authors have also studied Mo compounds with other alkyl-substituted imido groups: these compounds all follow a similar decomposition pathway, γ-H activation, with varying reaction barriers. The tert-pentyl, 1-adamantyl, and a cyclic imido (from 2,5-dimethylhexane-2,5-diamine) were systematically studied to probe the kinetics of this pathway. All of these compounds were fully characterized, including via single-crystal x-ray diffraction, and a total of 19 new structures are reported.2,5-Dimethyl-2,5-hexanediol (cas: 110-03-2) were involved in the experimental procedure.

2,5-Dimethyl-2,5-hexanediol(cas:110-03-2) is used as an intermediate in the preparation of 2.5-Dimethyl-2.5-bis(tertbutyl-peroxy)hexane. It is also used in the synthesis of six- and seven-membered heterocyclic boron compounds.Electric Literature of C8H18O2

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Category: alcohols-buliding-blocks《Cooperative interaction between acid and copper resistance in Escherichia coli》 was published in 2022. The authors were Kim, Yeeun;Lee, Seohyeon;Park, Kyungah;Yoon, Hyunjin, and the article was included in《Journal of Microbiology and Biotechnology》. The author mentioned the following in the article:

The persistence of pathogenic Escherichia coli under acidic conditions poses a serious risk to food safety, especially in acidic foods such as kimchi. To identify the bacterial factors required for acid resistance, transcriptomic anal. was conducted on an acid-resistant enterotoxigenic E. coli strain and the genes with significant changes in their expression under acidic pH were selected as putative resistance factors against acid stress. These genes included those associated with a glutamatedependent acid resistance (GDAR) system and copper resistance. E. coli strains lacking GadA, GadB, or YbaST, the components of the GDAR system, exhibited significantly attenuated growth and survival under acidic stress conditions. Accordantly, the inhibition of the GDAR system by 3- mercaptopropionic acid and aminooxyacetic acid abolished bacterial adaptation and survival under acidic conditions, indicating the indispensable role of a GDAR system in acid resistance. Intriguingly, the lack of cueR encoding a transcriptional regulator for copper resistance genes markedly impaired bacterial resistance to acid stress as well as copper. Conversely, the absence of YbaST severely compromised bacterial resistance against copper, suggesting an interplay between acid and copper resistance. These results suggest that a GDAR system can be a promising target for developing control measures to prevent E. coli resistance to acid and copper treatments. And 5-(hydroxymethyl)-2,4-dimethylpyridin-3-ol hydrochloride (cas: 148-51-6) was used in the research process.

5-(hydroxymethyl)-2,4-dimethylpyridin-3-ol hydrochloride(cas:148-51-6 Category: alcohols-buliding-blocks) is a vitamin B6 antimetabolite with diverse biological activities. It inhibits transport of pyridoxine , pyridoxal, and pyridoxamine in and reduces growth of S. carlsbergensis cells. DOP inhibits sphingosine-1-phosphate (S1P) lyase and reduces cyclic stretch-induced apoptosis in alveolar epithelial MLE-12 cells.

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Name: 3,7-Dimethyloctan-3-ol《Biogenic volatile organic compound (BVOC) emissions from forested areas in Turkey: Determination of specific emission rates for thirty-one tree species》 was published in 2014. The authors were Aydin, Yagmur Meltem;Yaman, Baris;Koca, Husnu;Dasdemir, Okan;Kara, Melik;Altiok, Hasan;Dumanoglu, Yetkin;Bayram, Abdurrahman;Tolunay, Doganay;Odabasi, Mustafa;Elbir, Tolga, and the article was included in《Science of the Total Environment》. The author mentioned the following in the article:

Normalized biogenic volatile organic compound (BVOC) emission rates for 31 tree species which cover 98% of national forested areas in Turkey were determined Field sampling was performed at 14 forested areas using a specific dynamic enclosure system. Selected branches of tree species were enclosed in a chamber consisting of a transparent Nalofan bag. Air flow was sampled from chamber inlet and outlet by Tenax-filled sorbent tubes during tree photosynthesis in the presence of sunlight. Several environmental parameters (temperature, humidity, photosynthetically-active radiation [PAR], CO₂) were continuously monitored inside and outside the enclosure chamber during sampling. Collected samples were analyzed by gas chromatog./mass spectrometry with thermal desorption. In total, 65 BVOC classified in 5 major groups (isoprene, monoterpenes, sesquiterpenes, oxygenated sesquiterpenes, other oxygenated compounds) were analyzed. Emission rates were determined by normalization to standard conditions (1000 μmol/m²-s PAR and 30° for isoprene, 30°C for the remaining compounds). In agreement with the literature, isoprene was mostly emitted by broad-leaved trees while coniferous species mainly emitted monoterpenes. Several tree species (sweet chestnut, silver lime, European alder) had higher monoterpene emissions, although they are broad-leaved species. High isoprene emissions were also observed for several coniferous species (Nordmann fir, Oriental spruce). The highest normalized total BVOC emission rate, 27.1 μg/g-hm was observed for Oriental plane while southern European flowering ash was the weakest BVOC emitter with a total normalized emission rate of 0.031 μg/g-h. Monoterpene emissions from broad-leaved species mainly consisted of sabinene, limonene, and trans-β-ocimene; α- and β-pinene and β-myrcene were generally emitted by coniferous species. Oxygenated compounds were the third most prominent BVOC group; sesquiterpenes had slightly lower contributions. And 3,7-Dimethyloctan-3-ol (cas: 78-69-3) was used in the research process.

3,7-Dimethyloctan-3-ol(cas:78-69-3) is a fatty alcohol that is 3-octanol substituted by methyl groups at positions 3 and 7.Name: 3,7-Dimethyloctan-3-ol Metabolite observed in cancer metabolism. It has a role as a human metabolite.

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts