Tag: 100-200

《Iridium(III) complex-containing non-conjugated polymers for non-volatile memory induced by switchable through-space charge transfer》 was written by Yang, Baojie; Tao, Peng; Ma, Chenxi; Tang, Runze; Gong, Tao; Liu, Shujuan; Zhao, Qiang. Related Products of 627-18-9 And the article was included in Journal of Materials Chemistry C: Materials for Optical and Electronic Devices in 2020. The article conveys some information:

Organic memory devices have recently attracted considerable interest to combat the increasing demands of data storage. Herein, taking advantage of the electron-deficient nature of iridium(III) complexes and the flexible polymer skeleton of non-conjugated polymers, a series of novel non-conjugated iridium(III) complex-containing polymers P2-P5 with non-volatile memory properties, and the corresponding model polymer P1, were rationally designed and synthesized. The memory effect of P1 is a static random-access memory type, while that of the polymers containing iridium(III) complexes are flash types. The ON/OFF current ratio of the devices based on P3 is as high as 103 and the device has good stability. It exhibits a long retention time of 104 s and both ON and OFF states, which survive up to more than 105 read cycles. The introduction of an iridium(III) complex contributes to the charge-transfer states from carbazole moieties to the iridium(III) complex, which also improves the crystallinity of polymers and realizes elec. bistability. In the part of experimental materials, we found many familiar compounds, such as 3-Bromopropan-1-ol(cas: 627-18-9Related Products of 627-18-9)

3-Bromopropan-1-ol(cas: 627-18-9) is used in the synthesis of fluorescent halide-sensitive quinolinium dyes, chiral, quaternary prolines through cyclization of quaternary amino acids and molten salt-polymers. It is utilized for the study of micellar media and in microemulsions based on cationic or a nonionic surfactant by reacting with phenols.Related Products of 627-18-9

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Smolobochkin, Andrey V.; Yakhshilikova, Lola Zh.; Gazinov, Almir S.; Vagapova, Liliya I.; Burilov, Alexander R.; Pudovik, Michael A. published an article in Chemistry of Heterocyclic Compounds (New York, NY, United States). The title of the article was 《Synthesis of novel macrocyclic and heterocyclic taurine derivatives based on the reaction of sodium 2-[(4,4-diethoxybutyl)amino]ethanesulfonate with phenols》.Recommanded Product: 4,4-Diethoxybutan-1-amine The author mentioned the following in the article:

An approach to the synthesis of novel macrocyclic and heterocyclic taurine derivatives I and II (R = H, Me, OH) based on the reaction of sodium 2-[(4,4-diethoxybutyl)amino]ethanesulfonate with phenols 2-R-3-OHC6H3OH in the presence of trifluoroacetic acid has been developed. In addition to this study using 4,4-Diethoxybutan-1-amine, there are many other studies that have used 4,4-Diethoxybutan-1-amine(cas: 6346-09-4Recommanded Product: 4,4-Diethoxybutan-1-amine) was used in this study.

4,4-Diethoxybutan-1-amine(cas: 6346-09-4) belongs to anime. Large quantities of aliphatic amines are made synthetically. The most widely used industrial method is the reaction of alcohols with ammonia at a high temperature, catalyzed by metals or metal oxide catalysts (e.g., nickel or copper). Mixtures of primary, secondary, and tertiary amines are thereby produced.Recommanded Product: 4,4-Diethoxybutan-1-amine

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In 2022,Xia, LiangLiang; Tu, HongJun; Zeng, Wen; Yang, XiaoLing; Zhou, Ming; Li, Linkai; Guo, Xiao published an article in Journal of Materials Chemistry A: Materials for Energy and Sustainability. The title of the article was 《A room-temperature self-healing elastomer with ultra-high strength and toughness fabricated via optimized hierarchical hydrogen-bonding interactions》.Safety of 2,6-Pyridinedimethanol The author mentioned the following in the article:

The preparation of room-temperature self-healing polymeric materials with good healing efficiency and high mech. strength is challenging. Two processes are essential to realize the room-temperature self-healing of materials: (a) a non-crystallized structure and interpenetration and diffusion of polymer chains; (b) fast reorganization of the intermol. bonds at damaged sites. Using these strategies, a new polyurethane elastomer is prepared in this study via three-step polyadditions using polytetramethylene ether glycol, isophorone diisocyanate, 2,6-pyridinedimethanol, and 4,4′-methylene bis(2-chloroaniline). The prepared elastomer possesses excellent tensile strength (34.1 MPa), high toughness (127.3 MJ m-3), high fracture energy (119.1 kJ m-2), and good stretchability (2014%). Furthermore, it exhibits strain-induced strengthening behavior and its mech. performances are superior to those of previously reported room-temperature self-healing polymer materials. The polyurethane elastomer synthesized via optimized hierarchical H-bonding interactions ultimately exhibited a synchronous self-healing efficiency of more than 83% with tensile strength, elongation, and toughness at 25°C ± 2°C after self-healing for 48 h. This study offers beneficial insights into the preparation of room-temperature self-healing polymers with high mech. strength. In the experiment, the researchers used many compounds, for example, 2,6-Pyridinedimethanol(cas: 1195-59-1Safety of 2,6-Pyridinedimethanol)

2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Safety of 2,6-Pyridinedimethanol

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Kim, Da-Som;Kim, Hoe Sung;Lee, Jookyeong;Pan, Jeong Hoon;Kim, Young Jun;Kim, Jae Kyeom;Woo, Seongmin;Shin, Eui-Cheol published 《Wasabia koreana Nakai: a preliminary study on nutrients and chemical compounds that may impact sensory properties》. The research results were published in《Molecules》 in 2018.Category: alcohols-buliding-blocks The article conveys some information:

In this study, the nutritional, functional, and chem. measurements of sensory attributes of different parts of wasabi, namely, leaf, petiole, and rhizome, were investigated. Proximate composition anal. showed the presence of high amounts of carbohydrates in the rhizome and amino acid composition anal. confirmed high proportions of glutamic acid and aspartic acid in all three parts. While proximate composition showed low lipid content in wasabi, ω-3 fatty acids accounted for a high proportion (>44%) of the total lipids. Wasabi leaves had high vitamin C and total phenolic contents, and thus demonstrated antioxidant capacity. Allyl isothiocyanate, which gives wasabi its characteristic pungent taste, was identified by gas chromatog./mass spectrometry and an electronic nose. On an electronic tongue, wasabi leaves showed compounds associated with sourness and saltiness while the petiole had high content of compounds associated with sweetness and bitterness. This study provides basic data for the utilization of wasabi parts as food materials based on their nutritional, functional, and chem. measure of sensory attributes. To complete the study, the researchers used 2,5-Dimethyl-2,5-hexanediol (cas: 110-03-2) .

2,5-Dimethyl-2,5-hexanediol(cas:110-03-2) was used in the synthesis of six- and seven-membered heterocyclic boron compounds containing intramolecular N-B bond.Category: alcohols-buliding-blocks

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Szczepanska, Katarzyna;Karcz, Tadeusz;Mogilski, Szczepan;Siwek, Agata;Kuder, Kamil J.;Latacz, Gniewomir;Kubacka, Monika;Hagenow, Stefanie;Lubelska, Annamaria;Olejarz, Agnieszka;Kotanska, Magdalena;Sadek, Bassem;Stark, Holger;Kiec-Kononowicz, Katarzyna published 《Synthesis and biological activity of novel tert-butyl and tert-pentylphenoxyalkyl piperazine derivatives as histamine H₃R ligands》. The research results were published in《European Journal of Medicinal Chemistry》 in 2018.Computed Properties of C11H16O The article conveys some information:

A series of twenty four new tert-Bu and tert-pentyl phenoxyalkylamine derivatives I [R = tetrahydrofuran-2-yl, pyridin-2-yl, pyridin-3-yl, pyridin-4-yl, pyrimidin-2-yl, pyrazin-2-yl; R¹ = Me, Et; Q = (CH₂)n, n = 1,2] was synthesized. Compounds with three to four carbon atoms alkyl chain spacer were evaluated for their binding properties at human histamine H₃ receptor (hH₃R). The highest affinities were observed for compounds I [R = pyridin-4-yl, R¹ = Me, Q = (CH₂)n, n = 1; R = pyridin-4-yl, R¹ = Me, n = 2; R = pyridin-4-yl, R¹ = Et, Q = (CH₂)n, n = 1; R = pyridin-4-yl, R¹ = Et, Q = (CH₂)n, n = 2] (K_i=16.0-120nM). As it was showed in docking studies, those specific heteroaromatic 4-N piperazine substituents might interact with one of the key receptor interacting amino acids. Moreover, the most promising compounds exhibited anticonvulsant activity in the maximal electroshock-induced seizure (MES) model in mice. Furthermore, the blood-brain barrier penetration, the functional H₃R antagonist potency as well as the pro-cognitive properties in the passive avoidance test were demonstrated for compound I [R = pyridin-4-yl, R¹ = Me, Q = (CH₂)n, n = 2]. In order to estimate drug-likeness of compound I [R = pyridin-4-yl, R¹ = Me, Q = (CH₂)n, n = 2] in silico and exptl. evaluation of metabolic stability in human liver microsomes was performed. In addition, paying attention to the results obtained within this study, the 4-pyridyl-piperazino moiety was established as a new bioisosteric piperidine replacement in H₃R ligands. The experimental procedure involved many compounds, such as 4-tert-Amylphenol (cas: 80-46-6) .

4-tert-acylphenol (cas:80-46-6) contains hydroxyl group. Owing to the presence of the polar OH alcohols are more water-soluble than simple hydrocarbons. Methanol, ethanol, and propanol are miscible in water. Butanol, with a four-carbon chain, is moderately soluble.Computed Properties of C11H16O

Reference:
Alcohol – Wikipedia,
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Ahn, Jeong-Hyeon;Kim, Ki-Hyun;Kim, Yong-Hyun;Kim, Bo-Won published 《Characterization of hazardous and odorous volatiles emitted from scented candles before lighting and when lit》. The research results were published in《Journal of Hazardous Materials》 in 2015.Application of 78-69-3 The article conveys some information:

Scented candles are known to release volatile organic compounds (VOC) with pleasant aromas and toxic components before lighting (off) and when lit (on). This work examined compositional changes of scented candle VOC under various settings simulating indoor use. Carbonyl compounds and other VOC emitted from 6 different candle types were analyzed for on/off conditions. The 6 candle types were: clean cotton (CT); floral (FL); kiwi melon (KW); strawberry (SB); vanilla (VN); and plain (PL). Although a large number of chems. were released before lighting and when lit, their profiles were noticeably distinguishable. Before lighting, various esters (n = 30) demonstrated the most dominant emissions. When lit, formaldehyde had the highest emission concentration (2098 ppb [SB], 1022 ppb [CT], 925 ppb [PL]). For most lit scented candles, there was a general tendency for increased concentrations of low b.p. compounds For some scented candle products, VOC emissions occurred strongly before lighting and when lit. For example, in terms of total VOC (ppbC), highest concentrations were observed with KW candles: 12,742 ppbC (on) and 2766 ppbC (off). Hence, results suggested certain scented candles should act as potent VOC emission sources in indoor environments, regardless of conditions, i.e., un-lit or lit.3,7-Dimethyloctan-3-ol (cas: 78-69-3) were involved in the experimental procedure.

3,7-Dimethyloctan-3-ol(cas:78-69-3) is a fatty alcohol that is 3-octanol substituted by methyl groups at positions 3 and 7.Application of 78-69-3 Metabolite observed in cancer metabolism. It has a role as a human metabolite.

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Scott, Kenneth G.;Daniels, Marie B. published 《The relation between iodine-131 metabolism, tumor growth, and regression》 in 1956. The article was appeared in 《Cancer Research》. They have made some progress in their research.Name: 5-(hydroxymethyl)-2,4-dimethylpyridin-3-ol hydrochloride The article mentions the following:

Ability of tumors to alter the normal metabolic pathway of I¹³¹ and compounds labeled with it (iodide-trapping syndrome) (I) is characterized by higher than normal retention of I¹³¹ by skin, muscle, gastrointestinal tract, and plasma, and a lower than normal thyroid uptake and urinary excretion of I¹³¹. I was elicited in rats by isografts and homografts of a transmissible fibrosarcoma, but not by homoiografts (which regressed after 5-7 days of growth). The data suggest that local and systemic I parallels progressive tumor growth and is absent in tumor implants destined to regress. To complete the study, the researchers used 5-(hydroxymethyl)-2,4-dimethylpyridin-3-ol hydrochloride (cas: 148-51-6) .

5-(hydroxymethyl)-2,4-dimethylpyridin-3-ol hydrochloride(cas:148-51-6 Name: 5-(hydroxymethyl)-2,4-dimethylpyridin-3-ol hydrochloride) is a strong antagonist of vitamin B6. Deoxypyridoxine hydrochloride has been used as an analytical reference standard for the quantification of the analyte in food samples using high performance liquid chromatography.

Reference:
Alcohol – Wikipedia,
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Sardjono, Ratnaningsih Eko;Kadarohman, Asep;Musthapa, Iqbal;Rachmawati, Rahmi published 《The development of halal aromatherapy products and identification of its chemical constituents》. The research results were published in《World Journal of Pharmacy and Pharmaceutical Sciences》 in 2018.SDS of cas: 78-69-3 The article conveys some information:

This study aimed to develop halal aromatherapy medicated oil from jasmine, rose, frangipani, tangerine and green tea oils from Indonesia. The halal aromatherapy medicated oil was produced by mixing the wintergreen oil with menthol, camphor and the essential oil resp. The composition of each material on the halal aromatherapy medicated oil was developed from the survey to obtain the proper composition The halal aromatherapy medicated oil was characterized by GC-MS to identify the chem. compounds contained. Result showed that the main component in the halal aromatherapy medicated oil for all variants was Me salicylate. The results of the survey showed that the tangerine variant was the most preferred with a percentage of 25.13%. Meanwhile, the rose variant produced the highest sensation of heat (29.74%). The products gained a pos. response with a percentage of interest to aromatherapy oil sales was 69.23%. And 3,7-Dimethyloctan-3-ol (cas: 78-69-3) was used in the research process.

3,7-Dimethyloctan-3-ol(cas:78-69-3) is a fatty alcohol that is 3-octanol substituted by methyl groups at positions 3 and 7.SDS of cas: 78-69-3 Metabolite observed in cancer metabolism. It has a role as a human metabolite.

Reference:
Alcohol – Wikipedia,
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Quality Control of 4-tert-Amylphenol《Profiling the ToxCast library with a pluripotent human (H9) stem cell line-based biomarker assay for developmental toxicity》 was published in 2020. The authors were Zurlinden, Todd J.;Saili, Katerine S.;Rush, Nathaniel;Kothiya, Parth;Judson, Richard S.;Houck, Keith A.;Hunter, E. Sidney;Baker, Nancy C.;Palmer, Jessica A.;Thomas, Russell S.;Knudsen, Thomas B., and the article was included in《Toxicological Sciences》. The author mentioned the following in the article:

The Stemina devTOX quickPredict platform is a human pluripotent stem cell-based assay that predicts the developmental toxicity potential based on changes in cellular metabolism following chem. exposure. Using this assay, we screened 1065 ToxCast phase I and II chems. in single-concentration or concentration-response for the targeted biomarker (ratio of ornithine to cystine secreted or consumed from the media). The dataset from the Stemina (STM) assay is annotated in the ToxCast portfolio as STM. Major findings from the anal. of ToxCast_STM dataset include (1) 19% of 1065 chems. yielded a prediction of developmental toxicity, (2) assay performance reached 79%-82% accuracy with high specificity (> 84%) but modest sensitivity (< 67%) when compared with in vivo animal models of human prenatal developmental toxicity, (3) sensitivity improved as more stringent weights of evidence requirements were applied to the animal studies, and (4) statistical anal. of the most potent chem. hits on specific biochem. targets in ToxCast revealed pos. and neg. associations with the STM response, providing insights into the mechanistic underpinnings of the targeted endpoint and its biol. domain. The results of this study will be useful to improving our ability to predict in vivo developmental toxicants based on in vitro data and in silico models. To complete the study, the researchers used 4-tert-Amylphenol (cas: 80-46-6) .

4-tert-acylphenol (cas:80-46-6) contains hydroxyl group. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Quality Control of 4-tert-Amylphenol

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Matamoros, Victor;Rendon-Mera, Alicia Maria;Pina, Benjami;Tadic, Djordje;Canameras, Nuria;Carazo, Nuria;Bayona, J. M. published 《Metabolomic and phenotypic implications of the application of fertilization products containing microcontaminants in lettuce (Lactuca sativa)》 in 2021. The article was appeared in 《Scientific Reports》. They have made some progress in their research.Category: alcohols-buliding-blocks The article mentions the following:

Cultivation practice using organic amendments is plausible to ensure global food security. However, plant abiotic stress due to the presence of metals and organic microcontaminants (OMCs) in fertilization products cannot be overlooked. In this study, we monitored lettuce metabolism and phenotypic response following the application of either sewage sludge (SS), the organic fraction of municipal solid waste, swine manure (SM), chem. fertilizers (CF), or no amendment (C) in a greenhouse facility. The exptl. set-up consisted of five treatments with five replicates (25 exptl. units randomly distributed). All fertilizers were supplied at the equivalent agronomic total nitrogen dose, but the occurrence of trace metals and/or OMCs was greater in the SS and SM than the rest. Non-target metabolomic anal. (high-resolution mass spectrometry coupled with partial least squares regression) identified more than 300 plant metabolites (amino acids, organic acids, sugar alcs., and sugars), 55 of which showed significant changes in their relative abundances depending on the type of amendment. Functional anal. indicated that the use of CF or SS increased the levels of metabolites involved in carbohydrate and nitrogen metabolism Therefore, although SS and SM fertilizers had a greater presence of heavy metals and/or OMCs, our results indicate that they did not induce measurable adverse effects in the lettuce phenotype or metabolism Metabolic changes between fertilizers (CF and SS vs. C and SM) were mainly due to nitrogen availability. To complete the study, the researchers used 3,7-Dimethyloctan-3-ol (cas: 78-69-3) .

3,7-Dimethyloctan-3-ol(cas:78-69-3) is a fatty alcohol that is 3-octanol substituted by methyl groups at positions 3 and 7.Category: alcohols-buliding-blocks Metabolite observed in cancer metabolism. It has a role as a human metabolite.

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts