Tag: 100-200

Pagano, Sandro; Montana, Giuseppe; Wickleder, Claudia; Schnick, Wolfgang published an article in 2009, the title of the article was Urea Route to Homoleptic Cyanates-Characterization and Luminescence Properties of [M(OCN)2(urea)] and M(OCN)2 with M = Sr, Eu.Safety of 2-Methyl-2-propylpropane-1,3-diol And the article contains the following content:

A novel approach for the synthesis of urea complexes and homoleptic cyanates of alk. earth metals and Eu is described. The compounds were fully characterized, including their magnetism and temperature-dependent luminescence properties. A novel approach for the synthesis of urea complexes and homoleptic cyanates of alk. earth metals and Eu is described. Direct reaction of urea with elemental Sr or Eu in closed ampuls at temperatures >120° yields [M(OCN)2(urea)] with M = Sr, Eu. According to single-crystal x-ray diffraction, the isotypic complexes exhibit a layer structure ([Eu(OCN)2(urea)]: space group P21/c, a 7.826(2), b 7.130(1), c 12.916(3) Å, β 99.76(3)°, Z = 4). Also, they were characterized by vibrational spectroscopy, thermal anal., magnetic measurements, and photoluminescence studies. Thermal treatment of [M(OCN)2(urea)] to 160-240° affords evaporation of urea and the subsequent formation of solvent-free homoleptic cyanates of Sr and Eu. The crystal structures of Sr(OCN)2 and Eu(OCN)2 were determined from x-ray powder diffraction data and refined by the Rietveld method. Both compounds crystallize in the orthorhombic space group Fddd and adopt the Sr(N3)2 type structure (Sr(OCN)2: a 6.1510(4), b 11.268(1), c 11.848(1) Å; Eu(OCN)2: a 6.1514(6), b 11.2863(12), c 11.8201(12) Å). The cyanates are stable up to 450°. Above 500° β-Sr(CN)2 and Eu2O2(CN)2 are formed. Excitation and emission spectra of [Eu(OCN)2(urea)], [Sr(OCN)2(urea)]:Eu2+, Eu(OCN)2, Sr(OCN)2:Eu2+ at different temperatures are reported. A strong green emission for all examined Eu-containing compounds due to a 4f6 5d1-4f7 transition is observed at low temperatures The luminescence properties are discussed in detail and are comparable to those of thiocyanates. Compared to the latter, a blue shift of the emission bands is observed due to the higher ionicity. The experimental process involved the reaction of 2-Methyl-2-propylpropane-1,3-diol(cas: 78-26-2).Safety of 2-Methyl-2-propylpropane-1,3-diol

The Article related to europium cyanate urea complex preparation structure thermal decomposition, strontium cyanate urea complex preparation thermal decomposition, luminescence europium cyanate urea complex, crystal structure europium strontium cyanate urea complex and other aspects.Safety of 2-Methyl-2-propylpropane-1,3-diol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Nesterova, Oksana V.; Nesterov, Dmytro S.; Vranovicova, Beata; Boca, Roman; Pombeiro, Armando J. L. published an article in 2018, the title of the article was Heterometallic CuIIFeIII and CuIIMnIII alkoxo-bridged complexes revealing a rare hexanuclear M6(μ-X)7(μ3-X)2 molecular core.Product Details of 2160-93-2 And the article contains the following content:

The novel hexanuclear complexes [Cu4Fe2(OH)(Piv)4(tBuDea)4Cl]·0.5CH3CN (1) and [Cu4Mn2(OH)(Piv)4(tBuDea)4Cl] (2) were prepared through one-pot self-assembly reactions of copper powder and iron(II) or manganese(II) chloride with N-tert-butyldiethanolamine (H2tBuDea) and pivalic acid (HPiv) in acetonitrile. Crystallog. studies revealed the uncommon mol. core type M6(μ-X)7(μ3-X)2 in 1 and 2, which can be viewed as a combination of two trimetallic M3(μ-X)2(μ3-X) fragments joined by three bridging atoms. The anal. and classification of the hexanuclear complexes having a M3(μ-X)2(μ3-X) moiety as a core forming fragment using data from the Cambridge Structural Database (CSD) were performed. Variable-temperature (1.8-300 K) magnetic susceptibility measurements of 1 showed a decrease of the effective magnetic moment value at low temperature, indicative of antiferromagnetic coupling between the magnetic centers (JFe-Cu/hc = -6.9 cm-1, JCu-Cu/hc = -4.1 cm-1, JFe-Fe/hc = -24.2 cm-1). Complex 1 acts as a catalyst in the reaction of mild oxidation of cyclohexane with H2O2, showing the yields of products, cyclohexanol and cyclohexanone, up to 17% using pyrazinecarboxylic acid as a promoter. In the oxidation of cis-1,2-dimethylcyclohexane with m-chloroperoxybenzoic acid (m-CPBA), 70% of retention of stereoconfiguration was observed for tertiary alcs. Compound 1 also catalyzes the amidation of cyclohexane with benzamide. In all three catalytic reactions the byproducts were investigated in detail and discussed. The experimental process involved the reaction of 2,2′-(tert-Butylazanediyl)diethanol(cas: 2160-93-2).Product Details of 2160-93-2

The Article related to copper iron manganese alkoxo butyldiethanolamine pivalate complex preparation magnetism, oxidation catalyst copper iron manganese alkoxo butyldiethanolamine pivalate, crystal structure copper iron manganese alkoxo butyldiethanolamine pivalate and other aspects.Product Details of 2160-93-2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

On April 15, 2010, Etoga, Jean-Louis G.; Ahmed, S. Kaleem; Patel, Sarjubhai; Bridges, Richard J.; Thompson, Charles M. published an article.Recommanded Product: 32462-30-9 The title of the article was Conformationally-restricted amino acid analogues bearing a distal sulfonic acid show selective inhibition of system Xc- over the vesicular glutamate transporter. And the article contained the following:

A panel of amino acid analogs and conformationally-restricted amino acids bearing a sulfonic acid were synthesized and tested for their ability to preferentially inhibit the obligate cysteine-glutamate transporter system X-c vs. the vesicular glutamate transporter (VGLUT). Several promising candidate mols. were identified: R/S-4-[4′-carboxyphenyl]-phenylglycine, a biphenyl substituted analog of 4-carboxyphenylglycine and 2-thiopheneglycine-5-sulfonic acid both of which reduced glutamate uptake at system X-c – by 70-75% while having modest to no effect on glutamate uptake at VGLUT. The experimental process involved the reaction of H-Phg(4-OH)-OH(cas: 32462-30-9).Recommanded Product: 32462-30-9

The Article related to glutamate uptake vglut inhibitor amino acid preparation, vesicular glutamate transporter inhibiting structure activity amino acid, phenylglycine aminothiophene sulfonic acid analog preparation, amino acid hydrolysis sulfonation sulfuric acid and other aspects.Recommanded Product: 32462-30-9

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

On April 3, 2008, Johansson, Rolf; Karlstroem, Sofia; Kers, Annika; Nordvall, Gunnar; Rein, Tobias; Slivo, Can published a patent.Synthetic Route of 87674-15-5 The title of the patent was Preparation of [(pyridinyl)ethyl]thio[(hydroxymethyl)alkyl]amino[1,3]thiazolo[4,5-d]pyrimidinone derivatives for use as therapeutic agents. And the patent contained the following:

Title compounds I [R1 = Me or CF3; R2 = halo, CN, or alkyl; R3 and R4 independently = H or Me; n = 0 to 2], and their pharmaceutically acceptable salts, are prepared and disclosed as therapeutic agents. Thus, e.g., II was prepared by oxidation of (2R)-2-[[5-[[(1S)-1-(5-chloropyridin-2-yl)ethyl]thio]-2-methoxy[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]-4-methylpentan-1-ol (preparation given). Select I were evaluated in recombinant human fractalkine hCX3CR1 binding assay, e.g., II demonstrated a Ki value of 5.8 (nM). Title compounds I are disclosed as therapeutic agents of neurodegenerative disorders, demyelinating disease, cardio- and cerebrovascular atherosclerotic disorders, peripheral artery disease, rheumatoid arthritis, pulmonary diseases such as COPD, asthma or pain. The experimental process involved the reaction of 1-(3-Fluoropyridin-4-yl)ethanol(cas: 87674-15-5).Synthetic Route of 87674-15-5

The Article related to pyrimidinone pyridinylethylthio hydroxymethylalkylamino thiazolo derivative preparation nervous system disease, pyridinylethylthio hydroxymethylalkylamino thiazolopyrimidinone derivative preparation atherosclerosis multiple sclerosis asthma and other aspects.Synthetic Route of 87674-15-5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yuan, Li-Ming; Ma, Wei; Xu, Mei; Zhao, Hui-Lin; Li, Yuan-Yuan; Wang, Rui-Lin; Duan, Ai-Hong; Ai, Ping; Chen, Xue-Xian published an article in 2017, the title of the article was Optical resolution and mechanism using enantioselective cellulose, sodium alginate and hydroxypropyl-β-cyclodextrin membranes.Computed Properties of 32462-30-9 And the article contains the following content:

Chiral solid membranes of cellulose, sodium alginate, and hydroxypropyl-β-cyclodextrin were prepared for chiral dialysis separations After optimizing the membrane material concentrations, the membrane preparation conditions and the feed concentrations, enantiomeric excesses of 89.1%, 42.6%, and 59.1% were obtained for mandelic acid on the cellulose membrane, p-hydroxy phenylglycine on the sodium alginate membrane, and p-hydroxy phenylglycine on the hydroxypropyl-β-cyclodextrin membrane, resp. To study the optical resolution mechanism, chiral discrimination by membrane adsorption, solid phase extraction, membrane chromatog., high-pressure liquid chromatog. ultrafiltration were performed. All of the exptl. results showed that the first adsorbed enantiomer was not the enantiomer that first permeated the membrane. The crystal structures of mandelic acid and p-hydroxy phenylglycine are the racematic compounds We suggest that the chiral separation mechanism of the solid membrane is “adsorption – association – diffusion,” which is able to explain the optical resolution of the enantioselective membrane. This is also the first report in which solid membranes of sodium alginate and hydroxypropyl-β-cyclodextrin were used in the chiral separation of p-hydroxy phenylglycine. The experimental process involved the reaction of H-Phg(4-OH)-OH(cas: 32462-30-9).Computed Properties of 32462-30-9

The Article related to chiral separation enantioselectivity cellulose sodium alginate hydroxypropyl beta cyclodextrin, cellulose, chiral separation, enantioselective membrane, hydroxypropyl-β-cyclodextrin, optical resolution mechanism of membrane, sodium alginate and other aspects.Computed Properties of 32462-30-9

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

On June 2, 2017, Vara, Brandon A.; Patel, Niki R.; Molander, Gary A. published an article.Related Products of 386704-04-7 The title of the article was O-Benzyl Xanthate Esters under Ni/Photoredox Dual Catalysis: Selective Radical Generation and Csp3-Csp2 Cross-Coupling. And the article contained the following:

Alkyl xanthate esters are perhaps best known for their use in deoxygenation chem. However, their use in cross-coupling chem. has not been productive, which is due, in part, to inadequate xanthate activation strategies. Herein, we report the use of O-benzyl xanthate esters, readily derived from alcs., as radical pronucleophiles in Csp3-Csp2 cross-couplings under Ni/photoredox dual catalysis. Xanthate (C-O) cleavage is found to be reliant on photogenerated (sec-butyl) radical activators to form new carbon-centered radicals primed for nickel-catalyzed cross-couplings. Mechanistic experiments support the fact that the key radical components are formed independently, and relative rates are carefully orchestrated, such that no cross reactivity is observed The experimental process involved the reaction of (6-(Trifluoromethyl)pyridin-3-yl)methanol(cas: 386704-04-7).Related Products of 386704-04-7

The Article related to cross coupling benzyl xanthate ester nickel photoredox dual catalysis, radical generation xanthate cross coupling, alkyl xanthate esters, carbon-centered radicals, cross-coupling, metal-catalyzed reactions, selective radical generation and other aspects.Related Products of 386704-04-7

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhang, Jun-Hui; Xie, Sheng-Ming; Wang, Bang-Jin; He, Pin-Gang; Yuan, Li-Ming published an article in 2018, the title of the article was A homochiral porous organic cage with large cavity and pore windows for the efficient gas chromatography separation of enantiomers and positional isomers.COA of Formula: C8H9NO3 And the article contains the following content:

Porous organic cages composed of discrete cage mols. have attracted considerable recent attention as gas adsorption materials and separation media. The authors report a homochiral porous organic cage CC5 with a large cavity and pore windows as a novel stationary phase for high-resolution gas chromatog. separations The capillary column was prepared by a static coating method. A large number of racemic compounds were resolved on the coated capillary column, including derivatized amino acids, alcs., alc. amines, esters, ethers, ketones, and epoxides. It is interesting that the CC5-coated capillary column exhibits significant chiral recognition complementarity to a com. β-DEX 120 column and a previously reported homochiral porous organic cage CC3-R-coated column, which could expand the range of the analytes amenable to separation on porous organic cage-based capillary columns. Also, the fabricated column also shows excellent selectivity for the separation of positional isomers, including the challenging ethylbenzene and xylene isomers. Exptl. results demonstrate an excellent separation performance and stability of the CC5-coated column, making it promising for gas chromatog. applications. The experimental process involved the reaction of H-Phg(4-OH)-OH(cas: 32462-30-9).COA of Formula: C8H9NO3

The Article related to homochiral porous organic cage large cavity efficient gas chromatog, gas chromatog enantiomer positional isomer separation, chiral separation, gas chromatography, homochiral porous organic cages, positional isomers, stationary phases and other aspects.COA of Formula: C8H9NO3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

On April 30, 2020, Zabela, Volha; Sampath, Chethan; Oufir, Mouhssin; Butterweck, Veronika; Hamburger, Matthias published an article.SDS of cas: 621-37-4 The title of the article was Single dose pharmacokinetics of intravenous 3,4-dihydroxyphenylacetic acid and 3-hydroxyphenylacetic acid in rats. And the article contained the following:

3,4-Dihydroxyphenylacetic acid (DOPAC) and 3-hydroxyphenylacetic acid (3-HPAA) are intestinal metabolites of the dietary flavonoid quercetin. DOPAC reportedly showed anxiolytic activity after i.p. administration in rats. The fate of these metabolites after consumption, and the pharmacol. properties of 3-HPAA in the body are largely unknown. The aim of the current study was to characterize pharmacokinetic properties of DOPAC and 3-HPAA after i.v. bolus application in rats. UHPLC-MS/MS methods for quantification of DOPAC and 3-HPAA levels in lithium heparin Sprague Dawley rat plasma were developed and validated according to international regulatory guidelines. Non-compartmental and compartmental analyses were performed. Pharmacokinetic profiles of DOPAC and 3-HPAA followed a two-compartment body model, with a fast distribution into peripheral tissues (half-lives of 3.27-5.26 min) and rapid elimination from the body (half-lives of 18.4-33.3 min). The experimental process involved the reaction of 3-Hydroxyphenylacetic acid(cas: 621-37-4).SDS of cas: 621-37-4

The Article related to pharmacokinetics dihydroxyphenylacetic hydroxyphenylacetic acid uhplc msms, 3,4-dihydroxyphenylacetic acid (pubchem cid: 547), 3-hpaa, 3-hydroxyphenylacetic acid (pubchem cid: 12122)., dopac, pharmacokinetics, uhplc-ms/ms, validation and other aspects.SDS of cas: 621-37-4

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

On October 31, 2005, Ghadwal, Rajendra Singh; Mehrotra, Ram C.; Singh, Anirudh published an article.Recommanded Product: 78-26-2 The title of the article was Synthesis and Spectroscopic Characterization of Two Different Types of Heterobimetallic Glycolate Complexes of Niobium(V). And the article contained the following:

An entirely new class of heterobimetallic homoleptic glycolate complexes Nb(OGO)3{Ta(OGO)2} [where G = CMe2CH2CH2CMe2 (G1) (3); CMe2CH2 CHMe (G2) (4); CHMeCHMe (G3) (5); CH2CMe2CH2 (G4) (6); CMe2CMe2(G5) (7); CH2CHMeCH2 (G6) (8); CH2CEt2CH2 (G7) (9); CH2CMe(Pr)CH2 (G8) (10)] were prepared by the reactions of Nb(OGO)2(OGOH) [G = G1 (1a); G2 (1b); G3 (1c); G4 (1d); G5 (1e); G6 (1f); G7 (1g); G8 (1h)] with Ta(OGO)2(OPri) (G = G1 (2a); G2 (2b); G3 (2c); G4 (2d); G5 (2e) G6 (2f); G7 (2g); G8 (2h)). In addition to the novel derivatives (2)-(10), the authors’ earlier studies on heterobimetallic glycolate-alkoxide derivatives were extended to derivatives Nb(OGO) [where M = Al n = 3, G = G3 (11); G4 (12); G6 (13) G7 (14); Gs (15); G9 = CH2CH2CH2 (16) and M = Ti (n = 4, G = G4) (17), Zr (n = 4, G = G4) (18)], which are conveniently prepared by the reactions of metalloligands Nb(OGO)2(OGOH) [G = G3 (1c); G4 (1d); G6 (1f); G7 (1g); G8 (1h); G9 (1i)] with different metal alkoxides. All of these new complexes were characterized by elemental analyses, mol. weight determinations, and spectroscopic (IR and 1H, 27Al-NMR) studies. Structural features of the new derivatives were elucidated from mol. weight and spectroscopic data. The experimental process involved the reaction of 2-Methyl-2-propylpropane-1,3-diol(cas: 78-26-2).Recommanded Product: 78-26-2

The Article related to niobium glycolate heterobimetallic complex with without alkoxide preparation, ir spectra niobium glycolate heterobimetallic complex with without alkoxide, nmr spectra niobium glycolate heterobimetallic complex with without alkoxide and other aspects.Recommanded Product: 78-26-2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

On December 11, 2008, Pinchuk, Anatoly; Weichert, Jamey P.; Longino, Marc published a patent.Recommanded Product: 2-Methyl-2-propylpropane-1,3-diol The title of the patent was Methods for the synthesis and use of phospholipid ether boronic acids and esters. And the patent contained the following:

The present invention discloses boronic acids and esters I [A = (CH2)n; X = boronic acid or ester; Y = NH2, NHR, NR2, NR+3; R = alkyl, arylalkly; n = 8 – 30], II [M = Li, Na, K, Cs, Rb] and III [Z = H, OH, OMe, OEt, OPr], of phospholipid ether (PLE) analogs and methods for their synthesis and use. A method of synthesizing a high specific activity PLE analog comprises: (a) coupling of a diboron with a PLE or alkyl phosphocholine (APC) analog in the presence of a catalyst to result in a boronic acid or ester PLE or APC analog; (b) optionally esterification the boronic acid of the PLE analog with 1,2- or 1,3-diols to result in the boronic esters of PLE or APC analogs; and, (c) optionally, reacting the boronic acid of ester of PLE or APC analog of (a) or (b) with sodium radiohalide, in the presence of an oxidant to result in a high specific activity radiohalogenated PLE or APC analog. Thus, NM404 (IV) was prepared from 4-IC6H4CH2Br via coupling with BrZn(CH2)11OAc, deacetylation with NaOH, Iodination with I2/PPH3/imidazole, coupling with BrZn(CH2)5CO2Et, saponification with NaOH, reduction with BH3·THF, phosphorylation with ethylene chlorophosphate, and reaction with NMe3. Coupling reaction of IV with bis(neopentylglycolato)diboron in MeOH containing KOAc and catalytic PdCl2(DPPF) gave II [X = B(OH)2], while coupling with bis(pinacolato)diboron gave II [X = pinacolborane]. Reaction of II [X = B(OH)2] with Na125I in aqueous NaOH containing chloramine-T gave 125I-NM404. The boronic acids and esters of phospholipid ether analogs described herein can be used in treating cancer and in particular can be used in conjunction with radiation therapy, such as external beam radiation therapy and neutron capture therapy to specifically target and kill cancer cells [see graphs]. The experimental process involved the reaction of 2-Methyl-2-propylpropane-1,3-diol(cas: 78-26-2).Recommanded Product: 2-Methyl-2-propylpropane-1,3-diol

The Article related to phospholipid ether boronic acid ester analog preparation cancer treatment, radiation therapy phospholipid ether boronic acid ester radiohalogenated analog, alkyl phosphocholine boronic acid ester analog preparation cancer treatment and other aspects.Recommanded Product: 2-Methyl-2-propylpropane-1,3-diol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts