Tag: 100-200

On November 30, 2021, Ding, Xiaowei; Liu, Kaihui; Yan, Qingyun; Liu, Xingyu; Chen, Ni; Wang, Guoliang; He, Shuai published an article.HPLC of Formula: 621-37-4 The title of the article was Sugar and organic acid availability modulate soil diazotroph community assembly and species co-occurrence patterns on the Tibetan Plateau. And the article contained the following:

Metabolites can mediate species interactions and the assembly of microbial communities. However, how these chems. relate to the assembly processes and co-occurrence patterns of diazotrophic assemblages in root-associated soils remains largely unknown. Here, we examined the diversity and assembly of diazotrophic communities and further deciphered their links with metabolites on Tibetan Plateau. We found that the distribution of sugars and organic acids in the root-associated soils was significantly correlated with the richness of diazotrophs. The presence of these two soil metabolites explains the variability in diazotrophic community compositions The differential concentrations of these metabolites were significantly linked with the distinctive abundances of diazotrophic taxa in same land types dominated by different plants or dissimilar soils by same plants. The assembly of diazotrophic communities is subject to deterministic ecol. processes, which are widely modulated by the variety and amount of sugars and organic acids. Organic acids, for instance, 3-(4-hydroxyphenyl)propionic acid and citric acid, were effective predictors of the characteristics of diazotrophic assemblages across desert habitats. Diazotrophic co-occurrence networks tended to be more complex and connected within different land types covered by the same plant species. The concentrations of multiple sugars and organic acids were coupled significantly with the distribution of keystone species, such as Azotobacter, Azospirillum, Bradyrhizobium, and Mesorhizobium, in the co-occurrence network. These findings provide new insights into the assembly mechanisms of root-associated diazotrophic communities across the desert ecosystems of the Tibetan Plateau. The experimental process involved the reaction of 3-Hydroxyphenylacetic acid(cas: 621-37-4).HPLC of Formula: 621-37-4

The Article related to sugar organic acid availability soil metabolite diazotroph community plateau, co-occurrence network, community assembly, diazotrophic diversity, sugars and organic acids, Plant Biochemistry: Metabolism and other aspects.HPLC of Formula: 621-37-4

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On December 1, 2021, da Silva, Dariane Trivisiol; Smaniotto, Franciele Aline; Costa, Isabella Ferreira; Baranzelli, Julia; Muller, Aline; Somacal, Sabrina; Monteiro, Camila Sant’Anna; Vizzotto, Marcia; Rodrigues, Eliseu; Barcia, Milene Teixeira; Emanuelli, Tatiana published an article.Formula: C8H8O3 The title of the article was Natural deep eutectic solvent (NADES): A strategy to improve the bioavailability of blueberry phenolic compounds in a ready-to-use extract. And the article contained the following:

This study investigated whether a ready-to-use extract obtained using a natural deep eutectic solvent (NADES) affects the pharmacokinetic profile of blueberry phenolic compounds compared to organic solvent (SORG)-extracted compounds SORG extract was administered as an aqueous solution after solvent removal. Wistar rats received a single dose of crude extract of blueberry obtained using NADES (CE-NADES) or SORG (CE-SORG), followed by LC-DAD-MS/MS anal. of blood and cecal feces. Non-compartmental pharmacokinetic anal. revealed that CE-NADES increased the bioavailability of anthocyanins by 140% compared to CE-SORG. CE-NADES increased the stability of phenolic compounds during in vitro digestion by delaying gastric chyme neutralization. These results suggest that besides being an eco-friendly solvent for the extraction of phytochems., choline chloride:glycerol:citric acid-based NADES can be used as a ready-to-use vehicle for increasing oral absorption of bioactive compounds such as anthocyanins. The experimental process involved the reaction of 3-Hydroxyphenylacetic acid(cas: 621-37-4).Formula: C8H8O3

The Article related to blueberry phenolic compound bioavailability natural deep eutectic solvent, absorption, anthocyanins, green solvent, intestinal stability, metabolites, pharmacokinetic, Food and Feed Chemistry: Analysis and other aspects.Formula: C8H8O3

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Alcohol – Wikipedia,
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On October 30, 2022, Yin, Zhibin; Dong, Tao; Huang, Wenjie; Du, Mingyi; Chen, Dong; Fernie, Alisdair R.; Yi, Ganjun; Yan, Shijuan published an article.Synthetic Route of 473-81-4 The title of the article was Spatially resolved metabolomics reveals variety-specific metabolic changes in banana pulp during postharvest senescence. And the article contained the following:

Banana is one of most popular fruits globally due to health-promoting and disease-preventing effects, yet little is known about in situ metabolic changes across banana varieties. Here, we integrated gold nanoparticle (AuNP)-assisted laser desorption/ionization mass spectrometry imaging (LDI-MSI) and metabolomics to investigate the spatiotemporal distribution and levels of metabolites within Brazil and Dongguan banana pulps during postharvest senescence. Metabolomics results indicated that both postripening stages and banana varieties contribute to metabolite levels. Benefiting from improved ionization efficiency of small-mol. metabolites and less peak interference, we visualized the spatiotemporal distribution of sugars, amino acids (AAs) and monoamines within pulps using AuNP-assisted LDI-MSI for the first time, revealing that AAs and monoamines exclusively accumulated in the middle region near the seed zone. Monosaccharides and di/trisaccharides were generally distributed across entire pulps but exhibited different accumulation patterns. These findings provide a guide for breeding new varieties and improving extraction efficiency of bioactive compounds The experimental process involved the reaction of 2,3-Dihydroxypropanoic acid(cas: 473-81-4).Synthetic Route of 473-81-4

The Article related to banana pulp tryptophan glyceric acid postharvest senescence metabolomics, amino acid, banana, mass spectrometry imaging, metabolomics, monoamine, soluble sugars, Food and Feed Chemistry: Analysis and other aspects.Synthetic Route of 473-81-4

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On June 30, 2022, Zhang, Yuandi; Xu, Jingguo; Ding, Fang; Deng, Wanyu; Wang, Xi; Xue, Yansong; Chen, Xiaoxue; Han, Bei-Zhong published an article.Related Products of 473-81-4 The title of the article was Multidimensional profiling indicates the shifts and functionality of wheat-origin microbiota during high-temperature Daqu incubation. And the article contained the following:

Wheat-origin microbiota is a critical factor in the assembly of the microbial community during high-temperature Daqu incubation. However, the succession and functional mechanisms of these microbial communities in Daqu are still unclear. This study investigated the shifts in microbiota diversity from the wheat to the end of incubation by the third generation Pacific Biosciences (PacBio) single-mol., real-time (SMRT) sequencing technol. Results indicated that Staphylococcus, Pantoea, Alternaria, and Mycosphaerella were the dominant genera of wheat-origin microbiota while Bacillus and Thermoascus were the most predominant bacterial and fungal genera of Daqu microbiota, resp. Metabolite detection revealed that volatile organic compounds (VOCs) changed obviously in different incubation stages and the 7th day to the 15th day of incubation was the critical period for the formation of VOCs. The content of non-VOCs, especially sugars, increased steeply in the first four days of incubation. The network anal. between microbes and metabolites showed that Thermoactinomyces and Staphylococcus had opposite correlations with most non-VOCs. Alternaria and Mycosphaerella had strong pos. correlations with fructose. As key functional fungal genera in wheat-origin microbiota, Mycosphaerella, Aspergillus, and Alternaria participated in multiple metabolic pathways (gluconeogenesis I, sucrose degradation III, pentose phosphate pathway, 5-aminoimidazole ribonucleotide biosynthesis I, Me ketone biosynthesis, and GDP-mannose biosynthesis) at the early stage of incubation, which played an important role in the formation of flavors and succession of microbiota. This work highlighted the shifts and functionality of wheat-origin microbiota in Daqu incubation, which can be a guideline to stabilize Daqu quality by wheat-origin microbiota control. The experimental process involved the reaction of 2,3-Dihydroxypropanoic acid(cas: 473-81-4).Related Products of 473-81-4

The Article related to multidimensional profiling wheat microbiota high temperature daqu incubation, daqu, incubation, microbiota, non-vocs, vocs, wheat, Food and Feed Chemistry: Analysis and other aspects.Related Products of 473-81-4

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Alcohol – Wikipedia,
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On July 31, 2021, Magdaleno-Tapia, Cristina; Quifer-Rada, Paola; Rodriguez-Rodriguez, Elena; Estevez-Santiago, Rocio; Waterhouse, Andrew L.; Lamuela-Reventos, Rosa M.; Olmedilla-Alonso, Begona; Perez-Jimenez, Jara published an article.Safety of 3-Hydroxyphenylacetic acid The title of the article was Evaluation of the potential of total proanthocyanidin content in feces as an intake biomarker. And the article contained the following:

Due to the health benefits associated with proanthocyanidins (PAs), it is useful to identify dietary PA biomarkers that can be determined by simple methods. Since increased levels of circulating PA metabolites are associated with increased fecal PA content, this study explores the spectrophotometric measurement of fecal PA content and its use as a biomarker of PA intake. To this end, fecal PA content was measured using an adaptation of Porters spectrophotometric method in samples from a preclin. study and an observational study. In the former, excretion of 250-400 mg PA polymer equivalent/100 g feces was observed during supplementation and the day after, together with a significant association (p < 0.05) between PA intake and the excretion of both intact PAs and some PA metabolites, i.e., (+)-catechin, (-)-epicatechin and syringic acid. No relationship between intake and excretion was found in the observational study, either for the entire group (mean excretion of 240 ± 226 mg PA polymer equivalent/100 g feces) or after stratification into tertiles of consumption. In conclusion, the spectrophotometric determination of total PA content in feces proved to be a valid compliance marker in a preclin. study, but it was not associated with PA intake in free-living subjects. The potential of total PA excretion in observational studies, determined in fecal samples collected the day before dietary recall or in several fecal samples from the same subject, remains to be elucidated, as does a complete validation of the method proposed here. The experimental process involved the reaction of 3-Hydroxyphenylacetic acid(cas: 621-37-4).Safety of 3-Hydroxyphenylacetic acid

The Article related to proanthocyanidin content feces intake biomarker, metabolism, observational study, polyphenols, preclinical study, Food and Feed Chemistry: Analysis and other aspects.Safety of 3-Hydroxyphenylacetic acid

Referemce:
Alcohol – Wikipedia,
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On March 31, 2021, Hao, Yuxin; Yang, Jing; Cui, Jingyan; Fan, Yanling; Li, Nana; Wang, Chunyu; Liu, Yongping; Dong, Yuemeng published an article.Synthetic Route of 621-37-4 The title of the article was Stability and mechanism of phenolic compounds from raspberry extract under in vitro gastrointestinal digestion. And the article contained the following:

Raspberry extract (RE) is a raspberry product with high anthocyanins and low sugar. In the present study, to evaluate the metabolic behavior of phenolic compounds of RE under in vitro digestion (gastric (GF), gastric to intestinal (G-IF), and colonic fermentation (CF)), the changes of 30 phenolic compounds were investigated by High Performance Liquid Chromatog.-Mass Spectrometry. The results showed that phenolic compounds were relatively stable in GF, but rapidly decreased in G-IF and CF. Five anthocyanins accounted for 61.1% of total polyphenol contents (TPCs). Among them, anthocyanins bound to glucose or with two hydroxyl groups on B-ring were metabolized more quickly. The catabolic activity of the human microbiota resulted in the production of a series of low mol. weight phenolics, such as hydroxybenzoic acids. Ellagic acid, accounting for 17.7% of TPCs, was rapidly metabolized to urolithin B and urolithin C in CF. Moreover, urolithin C showed the highest antioxidant activity in all ellagic acid metabolites by DPPH assay. Consequently, the metabolic behavior of phenolic compounds was mainly influenced by pH and intestinal microbiota, which provided the basis for further in vivo and in vitro study and efficient utilization of the extract The experimental process involved the reaction of 3-Hydroxyphenylacetic acid(cas: 621-37-4).Synthetic Route of 621-37-4

The Article related to stability mechanism raspberry extract phenolic compound gastrointestinal digestion, Food and Feed Chemistry: Analysis and other aspects.Synthetic Route of 621-37-4

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Alcohol – Wikipedia,
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On January 1, 2022, Podolean, Iunia; Coman, Simona M.; Bucur, Cristina; Teodorescu, Cristian; Kikionis, Stefanos; Ioannou, Efstathia; Roussis, Vassilios; Primo, Ana; Garcia, Hermenegildo; Parvulescu, Vasile I. published an article.Application of 473-81-4 The title of the article was Catalytic transformation of the marine polysaccharide ulvan into rare sugars, tartaric and succinic acids. And the article contained the following:

The green macroalga Ulva rigida represents a promising feedstock for biorefinary due to its fast growth and cosmopolitan distribution. The main component of the cell walls of U. rigida is a sulfated glucuronorhamnan polysaccharide known as ulvan. Herein it was found that due to the high (hydrogen)sulfate group content of ulvan, hydrothermal autohydrolysis at 130°C renders a high percentage of rhamnose (78-79% recovery from the initial content in the raw material), a rare sugar of high added value. In addition, acid catalysis by a triflate-based graphene oxide under oxygen-free conditions at 180°C affords moderate amounts of tartaric acid (24-26%). The same triflate-based graphene oxide catalyst under oxygen pressure yields remarkably high percentages of succinic acid (65%). The catalyst preserves its activity for at least five consecutive reuses. The experimental process involved the reaction of 2,3-Dihydroxypropanoic acid(cas: 473-81-4).Application of 473-81-4

The Article related to catalytic transformation marine polysaccharide ulvan rare sugar, Industrial Carbohydrates: General and other aspects.Application of 473-81-4

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Shoji, Yusuke; Kinoshita, Daiki; Furumi, Seiichi published an article in 2020, the title of the article was Straight-chain alkanediol derivatives leading to glassy cholesteric liquid crystals with visible reflection.Category: alcohols-buliding-blocks And the article contains the following content:

A series of straight-chain alkanediol derivatives possessing two cholesteryl groups through carbonate ester linkages (Cn-DiCh) showed thermotropic cholesteric liquid crystal phase with visible reflection. The thermally induced shifting ranges of reflection peaks were dependent on the central carbon chain length (n) of Cn-DiCh. Although the pristine Cn-DiCh showed narrow wavelength ranges of the reflection peaks by changing the temperature, prepared mixture of two different kinds of Cn-DiCh at their equivalent weight ratio, which exhibited the reflection peak shift throughout a wide visible-wavelength range between 400 nm and 850 nm. Moreover, the binary mixtures of Cn-DiCh were rapidly cooled from the CLC temperatures to 0°C, whereupon the reflection colors could be preserved even at room temperature over 2 mo. Such rapid cooling treatment enabled the straightforward preparation of solid-state G-CLCs with visible reflection characteristics, thereby leading to the applications of rewritable full-color imaging media. The experimental process involved the reaction of Pentane-1,5-diol(cas: 111-29-5).Category: alcohols-buliding-blocks

The Article related to cholesteric liquid crystal preparation reflection spectra, Alicyclic Compounds: Cyclohexanes and other aspects.Category: alcohols-buliding-blocks

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Alcohol – Wikipedia,
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On January 1, 2018, Akama, Tsutomu; Zhang, Yong-Kang; Freund, Yvonne R.; Berry, Pamela; Lee, Joanne; Easom, Eric E.; Jacobs, Robert T.; Plattner, Jacob J.; Witty, Michael J.; Peter, Rosemary; Rowan, Tim G.; Gillingwater, Kirsten; Brun, Reto; Nare, Bakela; Mercer, Luke; Xu, Musheng; Wang, Jiangong; Liang, Hao published an article.Product Details of 386704-04-7 The title of the article was Identification of a 4-fluorobenzyl L-valinate amide benzoxaborole (AN11736) as a potential development candidate for the treatment of Animal African Trypanosomiasis (AAT). And the article contained the following:

Novel L-valinate amide benzoxaboroles and analogs were designed and synthesized for a structure-activity-relationship (SAR) investigation to optimize the growth inhibitory activity against Trypanosoma congolense (T. congolense) and Trypanosoma vivax (T. vivax) parasites. The study identified 4-fluorobenzyl (1-hydroxy-7-methyl-1,3-dihydrobenzo[c][1,2]oxaborole-6-carbonyl)-L-valinate (5, AN11736), which showed IC50 values of 0.15 nM against T. congolense and 1.3 nM against T. vivax, and demonstrated 100% efficacy with a single dose of 10 mg/kg against both T. congolense and T. vivax in mouse models of infection (IP dosing) and in the target animal, cattle, dosed i.m. AN11736 has been advanced to early development studies. The experimental process involved the reaction of (6-(Trifluoromethyl)pyridin-3-yl)methanol(cas: 386704-04-7).Product Details of 386704-04-7

The Article related to valinate amide benzoxaborole analog preparation trypanosoma congolense vivax, benzoxaborole, cattle, lead optimisation, protozoan, sar, trypanosomiasis, Pharmacology: Structure-Activity and other aspects.Product Details of 386704-04-7

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Alcohol – Wikipedia,
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On August 31, 1992, Bazylak, Grzegorz published an article.Category: alcohols-buliding-blocks The title of the article was Retention behavior and molecular structure parameters of diethanolamine isomers in some reversed phase HPTLC systems. And the article contained the following:

The chromatog. behavior of twelve compounds structurally related to diethanolamine on four types of reversed phase, chem. bonded, hydrocarbonaceous silica gel has been studied with methanol – water as mobile phase. Linear, quadratic, and multi parametric correlations between the exptl. determined chromatog. parameter log k’, and the calculated mol. structure descriptors of the amino alcs. were examined Elution sequences on the octyl- and octadecyl-silane bonded phases were predicted most reliably by means of equations incorporating the valence mol. connectivity (χRv), Balaban and Weiner indexes. The experimental process involved the reaction of 2,2′-(tert-Butylazanediyl)diethanol(cas: 2160-93-2).Category: alcohols-buliding-blocks

The Article related to diethanolamine isomer retention structure hptlc, chromatog thin layer diethanolamine isomer structure, Pharmacology: Structure-Activity and other aspects.Category: alcohols-buliding-blocks

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Alcohol – Wikipedia,
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