Tag: 100-200

《Imidodiphosphorimidate (IDPi) as an efficient organocatalyst for controlled/living ring-opening polymerization of lactones》 was written by Zhang, Xun; Jiang, Yu; Ma, Qiang; Hu, Siping; Wang, Qinggang; Liao, Saihu. SDS of cas: 821-41-0 And the article was included in European Polymer Journal in 2020. The article conveys some information:

Imidodiphosphorimidate (IDPi) is demonsatreted as a novel and efficient acid/base bifunctional organocatalyst for controlled/living ring-opening polymerization of lactones, which delivered the metal-free poly(δ-valerolactone) and poly(ε-caprolactone) with excellent control over the mol. weight and narrow dispersity at a low catalyst loading under mild conditions. NMR and MALDI-TOF characterizations, kinetic study, and chain extension experiment suggest a well-controlled/living nature of the current ROP of lactones catalyzed by the IDPi catalyst. In addition to this study using 5-Hexen-1-ol, there are many other studies that have used 5-Hexen-1-ol(cas: 821-41-0SDS of cas: 821-41-0) was used in this study.

5-Hexen-1-ol(cas: 821-41-0) is used in cyclization to a tetrahydropyran by phenylselenoetherification. It is also used as a building block in synthetic chemistry.SDS of cas: 821-41-0

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《Visible-Light-Promoted Iododifluoromethylation of Alkenes via (Phosphonio)difluoromethyl Radical Cation》 was published in Organic Letters in 2020. These research results belong to Trifonov, Alexey L.; Panferova, Liubov I.; Levin, Vitalij V.; Kokorekin, Vladimir A.; Dilman, Alexander D.. Computed Properties of C6H12O The article mentions the following:

A reaction of an iododifluoromethylphosphonium salt with unactivated alkenes mediated by peri-xanthenoxanthene under blue-light irradiation is described. The reaction proceeds via activation of the carbon-iodine bond to generate (phosphonio)difluoromethyl radical cation, which attacks the double bond with subsequent quenching by the iodine. The intermediate phosphonium salts are easily hydrolyzed, furnishing products of iododifluoromethylation of alkenes. In addition to this study using 5-Hexen-1-ol, there are many other studies that have used 5-Hexen-1-ol(cas: 821-41-0Computed Properties of C6H12O) was used in this study.

5-Hexen-1-ol(cas: 821-41-0) is a volatile organic compound. Further, it is used to prepare 6-bromo-hex-1-ene by reaction with phosphorus tribromide.Computed Properties of C6H12O

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《Ligand-promoted cobalt-catalyzed radical hydroamination of alkenes》 was published in Nature Communications in 2020. These research results belong to Shen, Xuzhong; Chen, Xu; Chen, Jieping; Sun, Yufeng; Cheng, Zhaoyang; Lu, Zhan. Synthetic Route of C6H12O The article mentions the following:

Here, a ligand-promoted cobalt-catalyzed Markovnikov-type selective radical hydroamination of alkenes with diazo compounds was reported. This operationally simple protocol uses unsym. NNN-tridentate (UNT) ligand, readily available alkenes and hydrosilanes to construct hydrazones I (R = C6H5, 4-FC6H4, 3-pyridyl, etc.; R1 = Et, t-Bu, 4-MeOC6H4) with good functional group tolerance. The hydrazones can underwent nitrogen-nitrogen bond cleavage smoothly to deliver valuable amine derivatives Addnl., asym. intermol. hydroamination of unactivated aliphatic terminal alkenes using chiral N-imidazolinylphenyl 8-aminoquinoline (IPAQ) ligands has also been achieved to afford chiral amine derivatives II (R = Et, 4-FC6H4, C6H5CH2CH2, etc.; PG = Boc, Bz, (CH2)2CH(Ph)2, etc.) with good enantioselectivities. In the experiment, the researchers used many compounds, for example, 5-Hexen-1-ol(cas: 821-41-0Synthetic Route of C6H12O)

5-Hexen-1-ol(cas: 821-41-0) is a volatile organic compound. Further, it is used to prepare 6-bromo-hex-1-ene by reaction with phosphorus tribromide.Synthetic Route of C6H12O

Referemce:
Alcohol – Wikipedia,
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In 2019,Tetrahedron Letters included an article by Qiu, Zhenjiang; Zhu, Mingxiang; Zheng, Lu; Li, Jingya; Zou, Dapeng; Wu, Yangjie; Wu, Yusheng. HPLC of Formula: 18621-18-6. The article was titled 《Regioselective α-benzylation of 3-iodoazetidines via Suzuki cross-coupling》. The information in the text is summarized as follows:

An efficient protocol for the synthesis of α-benzyl azetidines I [R = 4-F3COC6H4, 2-F-C6H4, naphthalen-2-yl, etc.; R1 = C(O)OCH2C6H5, C(O)OC(CH3)3] starting from benzylboronic acid pinacol ester derivatives II and 3-iodoazetidine III was developed. A wide range of α-benzyl azetidine derivatives I was obtained in moderate to good yields with high regioselectivity (>99%). In the experimental materials used by the author, we found Azetidin-3-ol hydrochloride(cas: 18621-18-6HPLC of Formula: 18621-18-6)

Azetidin-3-ol hydrochloride(cas:18621-18-6) is one of azetidine.Azetidines (azacyclobutanes) constitute a well-known class of heterocyclic compounds. Azetidine scaffold has been discovered in several natural products.HPLC of Formula: 18621-18-6 Several pharmacologically important synthetic compounds also contain azetidine ring. Because of inherent ring strain, the synthesis of azetidines is a challenging endeavor.

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In 2019,Science China: Chemistry included an article by Li, Xiaonan; Chen, Pinhong; Liu, Guosheng. Formula: C6H12O. The article was titled 《Iodine(III) reagent (ABX-N3)-induced intermolecular anti-Markovnikov hydroazidation of unactivated alkenes》. The information in the text is summarized as follows:

Anti-Markovnikov hydroazidation of unactivated alkenes using ABX-N3 as an initiator has been developed at room temperature, wherein hydrogen azide (HN3) acts as both hydrogen source and azidation agent. Notably, the HN3 reagent was generated from azidotrimethylsilane (TMSN3) and acetic acid in situ. The reaction itself displays broad substrate scope, good yields, and excellent regioselectivities. In the experiment, the researchers used 5-Hexen-1-ol(cas: 821-41-0Formula: C6H12O)

5-Hexen-1-ol(cas: 821-41-0) is a volatile organic compound. Further, it is used to prepare 6-bromo-hex-1-ene by reaction with phosphorus tribromide.Formula: C6H12O

Referemce:
Alcohol – Wikipedia,
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In 2019,Green Chemistry included an article by Chakrabarti, Kaushik; Maji, Milan; Kundu, Sabuj. Application In Synthesis of 3-Pyridinemethanol. The article was titled 《Cooperative iridium complex-catalyzed synthesis of quinoxalines, benzimidazoles and quinazolines in water》. The information in the text is summarized as follows:

An efficient methodol. for the synthesis of a diverse class of N-heterocyclic moieties, such as quinoxalines, benzimidazoles and quinazolines, was developed in water using bio-renewable alcs. The quinoxalines were successfully synthesized from a wide range of diamines and nitroamines with diols in air. Interestingly, benzimidazoles and quinazolines were synthesized with excellent isolated yields without using any external base. Finally, the preparative scale synthesis of various N-heterocycles and pharmaceutically active quinoxalines established the practicability of this protocol. For this iridium system, a metal-ligand cooperative mechanism was proposed based on kinetic and DFT studies. After reading the article, we found that the author used 3-Pyridinemethanol(cas: 100-55-0Application In Synthesis of 3-Pyridinemethanol)

3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. Pyridine is widely used in the precursor to agrochemicals and pharmaceuticals. Also, it is used as an important reagent and organic solvent.Application In Synthesis of 3-Pyridinemethanol

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The author of 《Highly Efficient and Robust Enantioselective Liquid-Liquid Extraction of 1,2-Amino Alcohols utilizing VAPOL- and VANOL-based Phosphoric Acid Hosts》 were Pinxterhuis, Erik B.; Gualtierotti, Jean-Baptiste; Wezenberg, Sander J.; de Vries, Johannes G.; Feringa, Ben L.. And the article was published in ChemSusChem in 2018. Synthetic Route of C9H13NO The author mentioned the following in the article:

The large-scale production of enantiopure compounds in a cost-effective and environmentally friendly manner remains one of the major challenges of modern-day chem. The resolution of racemates through enantioselective liquid-liquid extraction was developed as a suitable solution but has remained largely underused, owing to a lack of highly efficient and robust chiral hosts to mediate the process. This paucity of hosts can in part be attributed to a poor understanding of the underlying principles behind these processes hindering the design of more efficient selectors. A previously untested class of hosts, VAPOL and VANOL derived phosphoric acids, was studied in depth for the efficient enantioselective liquid-liquid extraction of 1,2-amino alcs. A systematic investigation of extraction parameters was conducted, revealing many key interactions and DFT calculations illustrate the binding modes for the 1:1 complexes that are involved in chiral recognition. The resulting, now-optimized, procedures are highly robust and easy to implement. They are also easily scalable, as demonstrated by U-tube experiments In the experiment, the researchers used 2-Amino-2-(4-methylphenyl)ethan-1-ol(cas: 157142-48-8Synthetic Route of C9H13NO)

2-Amino-2-(4-methylphenyl)ethan-1-ol(cas: 157142-48-8) belongs to anime. Hydrogen peroxide (H2O2) and peroxy acids generally add an oxygen atom to the nitrogen of amines. With primary amines, this step is normally followed by further oxidation, leading to nitroso compounds, RNO, or nitro compounds, RNO2. Secondary amines are converted to hydroxylamines, R2NOH, and tertiary amines to amine oxides, R3NO.Synthetic Route of C9H13NO

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Alcohol – Wikipedia,
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The author of 《Gas-chromatographic analysis of aminothiol radioprotective compounds》 were Lofberg, R. T.. And the article was published in Analytical Letters in 1971. Formula: C5H14ClNS The author mentioned the following in the article:

A gas chromatog. method is described for aminothiols and disulfides. This method is based upon the formation of the trimethylsilyl derivatives and their separation by gas chromatog. The kinetics of the derivative formation were investigated. A synthetic method for C4 to C6 aminothiols is given.5-Aminopentane-1-thiol hydrochloride(cas: 31110-78-8Formula: C5H14ClNS) was used in this study.

5-Aminopentane-1-thiol hydrochloride(cas: 31110-78-8) belongs to thiols. Thiols show many reactions like those of the hydroxyl compounds, such as formation of thioesters and thioethers (sulfides). Toward oxidation, however, they differ profoundly from alcohols: whereas oxidation of an alcohol usually leads to a product in which the oxidation state of a carbon atom has been changed, oxidation of a thiol affects the sulfur atom. Formula: C5H14ClNS

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Related Products of 54-17-1On March 31, 2021, Moret, Florian; Delorme, Gael; Clement, Gilles; Grosjean, Claire; Lemaitre-Guillier, Christelle; Trouvelot, Sophie; Adrian, Marielle; Fontaine, Florence published an article in Physiologia Plantarum. The article was 《Esca-affected grapevine leaf metabolome is clone- and vintage-dependent》. The article mentions the following:

Esca is a complex grapevine trunk disease caused by wood-rotting ascomycetes and basidiomycetes and leading to several foliar and wood symptoms. Given that the esca expression can be influenced by several environmental, physiol., and genetic factors, foliar symptoms are inconsistent in incidence and prevalence and may appear 1 yr but not the following. We have previously reported a clone-dependent expression of the disease in cv Chardonnay. Owing to metabolome anal., we could discriminate the metabolite fingerprint of green leaves collected on diseased vines of clones 76 and 95. These clone-dependent fingerprints were year-dependent in intensity and nature. The present work was conducted to determine if the clone-dependent disease expression observed is specific to Chardonnay or if it also occurs in another cultivar. A plot located in the Jura vineyard (France) and planted with both 1004 and 1026 clones of Trousseau, a cultivar highly susceptible to esca, was thus selected and studied during 2017 and 2018. A year-dependent variation of the symptoms expression was first observed and a possible relationship with rainfall is hypothesized and discussed. Moreover, a higher percentage of the clone 1026 vines expressed disease, compared to the 1004 ones, suggesting the higher susceptibility of this clone. Finally, metabolomic analyzes of the remaining green leaves (i.e, without symptom expression) of partial esca-apoplectic vines allowed us to confirm a clone-dependent metabolic response to the disease. The metabolite fingerprints obtained differed in nature and intensity to those previously reported for Chardonnay and also between years. In the experimental materials used by the author, we found rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol(cas: 54-17-1Related Products of 54-17-1)

rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol(cas: 54-17-1) is the monohydrate form of the alpha isoform of D-glucopyranose, a synthetic simple monosaccharide that is used as an energy source.Related Products of 54-17-1

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Quality Control of 5-Hexen-1-olIn 2021 ,《Oxidative additions of alkynyl/vinyl iodides to gold and gold-catalyzed vinylation reactions triggered by the MeDalphos ligand》 was published in Chemical Science. The article was written by Rodriguez, Jessica; Tabey, Alexis; Mallet-Ladeira, Sonia; Bourissou, Didier. The article contains the following contents:

The hemilabile Ad2P(o-C6H4)NMe2 ligand promotes fast, quant. and irreversible oxidative addition of alkynyl and vinyl iodides to gold. The reaction is general. It works with a broad range of substrates of various electronic bias and steric demand, and proceeds with complete retention of stereochem. from Z and E vinyl iodides. Both alkynyl and vinyl iodides react faster than aryl iodides. The elementary step is amenable to catalysis. Oxidative addition of vinyl iodides to gold and π-activation of alkenols (and N-alkenyl amines) at gold have been combined to achieve hetero-vinylation reactions. A number of functionalized heterocycles, i.e. tetrahydrofurans, tetrahydropyrans, oxepanes and pyrrolidines were obtained thereby (24 examples, 87% average yield). Taking advantage of the chemoselectivity for vinyl iodides over aryl iodides, sequential transformations involving first a hetero-vinylation step and then a C-N coupling, a C-C coupling or an heteroarylation were achieved from a vinyl/aryl bis-iodide substrate. The results came from multiple reactions, including the reaction of 5-Hexen-1-ol(cas: 821-41-0Quality Control of 5-Hexen-1-ol)

5-Hexen-1-ol(cas: 821-41-0) is used in cyclization to a tetrahydropyran by phenylselenoetherification. It is also used as a building block in synthetic chemistry.Quality Control of 5-Hexen-1-ol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts