Tag: 100-200

The author of 《Exceptionally slow magnetic relaxation in a mononuclear hexacoordinate Ni(II) complexã€?were Titis, Jan; Chrenkova, Veronika; Rajnak, Cyril; Moncol, Jan; Valigura, Dusan; Boca, Roman. And the article was published in Dalton Transactions in 2019. Name: 2,6-Pyridinedimethanol The author mentioned the following in the article:

A hexacoordinate mononuclear [Ni(pydm)2](dnbz)2 complex shows field-induced slow magnetic relaxation with two or three relaxation channels that are strongly supported by an external magnetic field. At BDC = 0.8 T and T = 1.9 K, the low-frequency (LF) relaxation time is as slow as τ(LF) = 1.3 s with the mole fraction of x(LF) = 0.47. In the experiment, the researchers used 2,6-Pyridinedimethanol(cas: 1195-59-1Name: 2,6-Pyridinedimethanol)

2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. When pyridine is adsorbed on oxide surfaces or in porous materials, the following species are commonly observed: (i) pyridine coordinated to Lewis acid sites, (ii) pyridine H-bonded to weakly acidic hydroxyls, and (iii) protonated pyridine. At high coverage, physisorbed pyridine and protonated dimers can also be observed.Name: 2,6-Pyridinedimethanol

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Related Products of 89466-08-0In 2020 ,《Rhodium-Catalyzed ortho-Selective Carbene C-H Insertion of Unprotected Phenols Directed by a Transient Oxonium Ylide Intermediateã€?appeared in Organic Letters. The author of the article were Guo, Rui-Ting; Zhang, Ya-Lin; Tian, Jun-Jie; Zhu, Ke-Yu; Wang, Xiao-Chen. The article conveys some information:

Ortho-Selective carbene C-H insertion of unprotected phenols is achieved with di-Me diazomalonate under the catalysis of [Rh(COD)Cl]2. After the C-H insertion, subsequent cyclization and electrophilic addition of another carbene mol. affords tris-carboxylate-substituted 2-benzofuranones as the final reaction products. The enantioselective variant has been developed with the use of chiral diene ligands. Mechanistic experiments indicate that a transient oxonium ylide directing group might be responsible for the regiocontrol at the C-H activation step.2-Hydroxyphenylboronic acid(cas: 89466-08-0Related Products of 89466-08-0) was used in this study.

2-Hydroxyphenylboronic acid(cas: 89466-08-0) belongs to acyl phenylboronic acid. Phenylboronic acid (PBA) has been used to extract β-blockers (a class of aminoalcohol-containing drugs) from aqueous solution, rat, and human plasma. Related Products of 89466-08-0

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Synthetic Route of C6H13NOIn 2018 ,《Structural Optimization of a Pyridinylimidazole Scaffold: Shifting the Selectivity from p38α Mitogen-Activated Protein Kinase to c-Jun N-Terminal Kinase 3ã€?appeared in ACS Omega. The author of the article were Ansideri, Francesco; Macedo, Joana T.; Eitel, Michael; El-Gokha, Ahmed; Zinad, Dhafer S.; Scarpellini, Camilla; Kudolo, Mark; Schollmeyer, Dieter; Boeckler, Frank M.; Blaum, Baerbel S.; Laufer, Stefan A.; Koch, Pierre. The article conveys some information:

Starting from known p38α mitogen-activated protein kinase (MAPK) inhibitors, a series of inhibitors of the c-Jun N-terminal kinase (JNK) 3 was obtained. Altering the substitution pattern of the pyridinylimidazole scaffold proved to be effective in shifting the inhibitory activity from the original target p38α MAPK to the closely related JNK3. In particular, a significant improvement for JNK3 selectivity could be achieved by addressing the hydrophobic region I with a small Me group. Furthermore, addnl. structural modifications permitted to explore structure-activity relationships. The most potent inhibitor 4-(4-methyl-2-(methylthio)-1H-imidazol-5-yl)-N-(4-morpholinophenyl)pyridin-2-amine showed an IC50 value for the JNK3 in the low triple digit nanomolar range and its binding mode was confirmed by x-ray crystallog. In the experimental materials used by the author, we found trans-4-Aminocyclohexanol(cas: 27489-62-9Synthetic Route of C6H13NO)

trans-4-Aminocyclohexanol(cas: 27489-62-9) belongs to anime. In organic chemistry, amines are compounds and functional groups that contain a basic nitrogen atom with a lone pair. Amines are formally derivatives of ammonia (NH3), wherein one or more hydrogen atoms have been replaced by a substituent such as an alkyl or aryl group (these may respectively be called alkylamines and arylamines; amines in which both types of substituent are attached to one nitrogen atom may be called alkylarylamines).Synthetic Route of C6H13NO

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Product Details of 18621-18-6In 2018 ,《Multiheterocyclic Motifs via Three-Component Reactions of Benzynes, Cyclic Amines, and Protic Nucleophilesã€?appeared in Organic Letters. The author of the article were Ross, Sean P.; Hoye, Thomas R.. The article conveys some information:

A broadly general, three-component reaction strategy for the construction of compounds containing multiple heterocycles is described. Thermal benzyne formation (by the hexadehydro-Diels-Alder (HDDA) reaction) in the presence of tertiary cyclic amines and a protic nucleophile (HNu) gives, via ring-opening of intermediate ammonium ion/Nu- ion pairs, heterocyclic products. Many reactions are efficient even when the stoichiometric loading of the three reactants approaches unity. Use of HOSO2CF3 as the HNu gives ammonium triflate intermediates, which can then be ring opened by an even wider variety of nucleophiles. The results came from multiple reactions, including the reaction of Azetidin-3-ol hydrochloride(cas: 18621-18-6Product Details of 18621-18-6)

Azetidin-3-ol hydrochloride(cas:18621-18-6) is one of azetidine.Azetidines (azacyclobutanes) constitute a well-known class of heterocyclic compounds. Azetidine scaffold has been discovered in several natural products.Product Details of 18621-18-6 Several pharmacologically important synthetic compounds also contain azetidine ring. Because of inherent ring strain, the synthesis of azetidines is a challenging endeavor.

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In 2022,Wang, Zhigang; Lan, Yingjia; Liu, Peng; Li, Xiaohong; Zhao, Youliang published an article in Polymer Chemistry. The title of the article was 《Rational design of a multi-in-one heterofunctional agent for versatile topological transformation of multisite multisegmented polystyrenesã€?Electric Literature of C3H7BrO The author mentioned the following in the article:

Architecture-transformable polymers can expand the family of stimuli-responsive polymers and be utilized to reveal the topol. effect. Despite the tremendous progress, it remains a great challenge to achieve single polymer based on-demand topol. transformations with reduced, similar and enhanced molar masses. To address this challenge, an initiating, coupling and pH/thermo-labile agent is designed to synthesize linker-reactive multisite multisegmented polymers (LMMPs) via tandem ATRP and ATRC, followed by intermol. anthracene dimerization to generate single-chain folding polystyrenes. Meanwhile, bromine and hydroxyl groups are incorporated into each linker to generate graft copolymers comprising poly(tert-Bu acrylate) and poly(ε-caprolactone) side chains. The self-immolative tertiary amine ester linker allows thermo-triggered topol. transformation from multisegmented, intrachain folding and graft polymers to one-segment polymers. The robust one-shot strategy can afford a promising platform to construct heterofunctional multisegmented polymers with tailor-made structures and functions. After reading the article, we found that the author used 3-Bromopropan-1-ol(cas: 627-18-9Electric Literature of C3H7BrO)

3-Bromopropan-1-ol(cas: 627-18-9) is used in the synthesis of fluorescent halide-sensitive quinolinium dyes, chiral, quaternary prolines through cyclization of quaternary amino acids and molten salt-polymers. It is utilized for the study of micellar media and in microemulsions based on cationic or a nonionic surfactant by reacting with phenols.Electric Literature of C3H7BrO

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In 2022,Li, Xinwei; Bian, Jiqing; Fu, Mingyang; Zhang, Yan; Liu, Hongmei; Gao, Baoxiang published an article in Analytical Methods. The title of the article was 《Photostable fluorescent probes based on multifunctional group substituted naphthalimide dyes for imaging of lipid droplets in live cellsã€?SDS of cas: 18621-18-6 The author mentioned the following in the article:

We designed and synthesized multifunctional group substituted naphthalimide (MFGNI) dyes by introducing glycine Et ester and azetidine on 1,8-naphthalimide. With different azetidine substituents, the emission of the MFGNI dyes was shifted from blue to green. These MFGNI dyes exhibited high photoluminescence quantum yields (61% to 85%) and large Stokes shifts (67 nm). The amides and hydroxyl groups improved the photostability of the MFGNI dyes. Due to the small mol. weight and lipophilic properties, these MFGNI dyes specifically stained lipid droplets in living cells. After reading the article, we found that the author used Azetidin-3-ol hydrochloride(cas: 18621-18-6SDS of cas: 18621-18-6)

Azetidin-3-ol hydrochloride(cas:18621-18-6) is one of azetidine.Azetidines (azacyclobutanes) constitute a well-known class of heterocyclic compounds. Azetidine scaffold has been discovered in several natural products.SDS of cas: 18621-18-6 Several pharmacologically important synthetic compounds also contain azetidine ring. Because of inherent ring strain, the synthesis of azetidines is a challenging endeavor.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kim, Hansol; Khazi, Mohammed Iqbal; Kim, Jong-Man published an article in 2021. The article was titled 《Preparation and colorimetric response of an aldehyde-functionalized macrocyclic diacetylene-derived polydiacetyleneã€? and you may find the article in Dyes and Pigments.Category: alcohols-buliding-blocks The information in the text is summarized as follows:

Stimulus-responsive colorimetric materials have found great utility in a variety of fields including anticounterfeiting, display and sensor technologies. Herein, the authors describe a colorimetric polydiacetylene (PDA) that is generated by polymerization of the aldehyde-functionalized macrocyclic diacetylene, MCDA-CHO. UV irradiation of self-assembled MCDA-CHO generates a blue-color PDA, which undergoes a sequential blue-purple-brown-orange color change upon heating. Interestingly, the PDA displays a remarkably high temperature reversible thermochromism between 30 (blue) and 180° (reddish-brown). In addition to displaying reversible thermochromism, polymerized MCDA-CHO can be employed for colorimetric differentiation between aromatic and aliphatic primary amines. Accordingly, a blue-to-reddish brown color change takes place when the PDA is exposed to primary aniline derivatives while no color change occurs in the presence of aliphatic primary amines. IR spectroscopic anal. confirms that this colorimetric selectivity is a consequence of the facile formation of imine groups through reactions of the aldehyde moieties in the PDA with anilines. The results came from multiple reactions, including the reaction of 3,5-Dihydroxybenzaldehyde(cas: 26153-38-8Category: alcohols-buliding-blocks)

3,5-Dihydroxybenzaldehyde(cas: 26153-38-8) is a building block. It has been used in the synthesis of 2,4-dimethylbenzoylhydrazones with antileishmanial and antioxidant activities.Category: alcohols-buliding-blocks

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Zhang, Haowen; Zhou, Cen; Zheng, Ying; Zhang, Xiao published an article in 2021. The article was titled 《Isotruxene-based porous polymers as efficient and recyclable photocatalysts for visible-light induced metal-free oxidative organic transformationsã€? and you may find the article in Green Chemistry.HPLC of Formula: 89466-08-0 The information in the text is summarized as follows:

Two new isotruxene-based porous polymers were prepared and demonstrated to be highly efficient, metal-free heterogeneous photocatalysts for oxidative transformations using air as the mild oxidant under visible-light irradiation Both catalysts show excellent recyclability. In addition, the reactions can be performed in water, further indicating the greenness of this method. The results came from multiple reactions, including the reaction of 2-Hydroxyphenylboronic acid(cas: 89466-08-0HPLC of Formula: 89466-08-0)

2-Hydroxyphenylboronic acid(cas: 89466-08-0) belongs to acyl phenylboronic acid. Phenylboronic acid (PBA) has been used to extract β-blockers (a class of aminoalcohol-containing drugs) from aqueous solution, rat, and human plasma. HPLC of Formula: 89466-08-0

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kim, Hyungi; Lee, Sungmin; Min, Jun Sik; Kim, Eunsu; Choi, Junwon; Ko, JeongGil; Kim, Eunha published an article in 2021. The article was titled 《Fluorescent sensor array for high-precision pH classification with machine learning-supported mobile devicesã€? and you may find the article in Dyes and Pigments.Application of 89466-08-0 The information in the text is summarized as follows:

There is growing research interest from many scientific, healthcare, and industrial applications toward the development of high-precision optical pH sensors that cover a broad pH range. Despite enthusiastic endeavors, however, it remains challenging to develop cost-effective, high-precision, and broadband working paper-strip-type optical pH measurement systems, particularly for on-site or in-the-field pH sensing applications. We develop a fluorescent array based on a KIz system for accurate pH level classification. Based on the indolizine fluorescent core skeleton, a library of 30 different pH-responsive fluorescent probes is rationally designed and efficiently synthesized. Spotting the compounds in a checkered pattern (5 x 6) allows for the development of a disposable compound array on wax-printed cellulose paper. Compounds sharing a single chem. core skeleton result in the interrogation of all the components of a system with a single excitation light, resulting in a simple system design for pH classification. Furthermore, we design a 3D-printed enclosure to capture the fluorescence pattern changes of the array by using an intelligent, smartphone-based, handheld pH detection system. Specifically, by exploiting a random forest-based machine learning algorithm on a smartphone, we can effectively analyze the fluorescence pattern changes. Our results suggest that our proposed system can classify pH levels in fine-grain (0.2 pH) units.2-Hydroxyphenylboronic acid(cas: 89466-08-0Application of 89466-08-0) was used in this study.

2-Hydroxyphenylboronic acid(cas: 89466-08-0) belongs to acyl phenylboronic acid. Phenylboronic acid (PBA) has been used to extract β-blockers (a class of aminoalcohol-containing drugs) from aqueous solution, rat, and human plasma. Application of 89466-08-0

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wan, Xueting; Jiang, Jian; Tu, Yanyan; Xu, Siyuan; Li, Jing; Lu, Huanjun; Li, Zhikai; Xiong, Lianhu; Li, Xiaohong; Zhao, Youliang; Tu, Yingfeng published an article in 2021. The article was titled 《A cascade strategy towards the direct synthesis of green polyesters with versatile functional groupsã€? and you may find the article in Polymer Chemistry.HPLC of Formula: 1195-59-1 The information in the text is summarized as follows:

The synthesis of polyesters with the desired functional groups without addnl. protection and deprotection steps remains a worthwhile challenge to polymer chemists. Herein, we put forward a solution for the direct preparation of green copolyesters with versatile functionalities via the cascade polycondensation-coupling ring-opening polymerization (PROP) using a biobased cyclic diester ethylene brassylate as the monomer and functional diols/polyether diols as initiators. The combination of two polymerization processes into one system enables the facile synthesis of biodegradable polyesters with versatile functionalities, including alkane, alkene, alkyne, aromatic, halide, ether, and amide functional groups, and poly(ether ester) multiblock copolymers, together with high functional group contents (50% molar ratio to brassylate) and relatively high mol. weights (up to 6 x 104 Da). The cascade strategy provides a feasible method for the synthesis of high functional group content polyesters with tailor-made properties, highly effective for post-modifications that are suitable for a variety of applications. In the part of experimental materials, we found many familiar compounds, such as 2,6-Pyridinedimethanol(cas: 1195-59-1HPLC of Formula: 1195-59-1)

2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. HPLC of Formula: 1195-59-1

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