Tag: 100-200

In 2019,ChemCatChem included an article by Bottaro, Fabrizio; Madsen, Robert. Electric Literature of C7H7BrO. The article was titled 《In Situ Generated Cobalt Catalyst for the Dehydrogenative Coupling of Alcohols and Amines into Iminesã€? The information in the text is summarized as follows:

An in situ formed cobalt catalyst is developed from cobalt(II) bromide, bis[2-(diisopropylphosphino)-4-methylphenyl]amine and zinc metal. The catalyst mediates the acceptorless dehydrogenative coupling of alcs. and amines into imines with the release of hydrogen gas and the transformation is applied to the synthesis of a variety of imines from different alcs. and amines. The mechanism is investigated with labeled substrates; and based on the results, a cobalt(I) PNP complex is believed to be the catalytically active species which abstracts hydrogen gas from the alc. through a metal ligand bifunctional pathway. The results came from multiple reactions, including the reaction of (4-Bromophenyl)methanol(cas: 873-75-6Electric Literature of C7H7BrO)

(4-Bromophenyl)methanol(cas: 873-75-6) undergoes three-component reaction with acetylferrocene and arylboronic acid to give ferrocenyl ketones containing biaryls.Electric Literature of C7H7BrO It is used in the synthesis of amphiphilic, symmetric rod-coil, triblock copolymer of poly(9,9-didodecylfluorene-2,7-diyl) and poly(hydroxyl ethyl methacrylate)

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2018,Fujiki, Katsumasa; Tanaka, Katsunori published 《Bis[ N , N ‘-(2-indanolyl)]-1,5-diazacyclooctane as Unique Metal Ligand: Self-Assembly of Palladium Nanoparticles and Catalytic Reactivity on C-C Bond Formationã€?Synthesis published the findings.Application of 126456-43-7 The information in the text is summarized as follows:

A previously unreported 1,5-diazacyclooctane-palladium(II) complex was synthesized using bis[ N, N’-(2-indanolyl)]-1,5-diazacyclooctane, which was readily prepared via a novel [4+4] homocyclization of the unsaturated imine intermediate generated from acrolein and 1-amino-2-indanol. Interestingly, the 1,5-diazacyclooctane-palladium(II) complex self-assembled to form palladium nanoparticles. This approach readily provided palladium nanoparticles simply by heating a mixture of palladium(II) acetate and bis[ N, N’-(2-indanolyl)]-1,4-diazacyclooctane in dichloroethane at mild temperatures The 1,5-diazacyclooctane-derivative-palladium nanoparticles were successfully deployed in synthetic applications as a heterogeneous catalyst, facilitating Suzuki coupling and a challenging C-C bond formation via C(sp 3)-H activation under low catalyst loading conditions.(1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol(cas: 126456-43-7Application of 126456-43-7) was used in this study.

(1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol(cas: 126456-43-7) belongs to anime. The methylamines occur in small amounts in some plants. Many polyfunctional amines (i.e., those having other functional groups in the molecule) occur as alkaloids in plants—for example, mescaline, 2-(3,4,5-trimethoxyphenyl)ethylamine; the cyclic amines nicotine, atropine, morphine, and cocaine; and the quaternary salt choline, N-(2-hydroxyethyl)trimethylammonium chloride, which is present in nerve synapses and in plant and animal cells.Application of 126456-43-7

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

《Titanium complexes containing tridentate [ONO] type Schiff base ligands for the cycloaddition reaction of CO2 to propylene oxideã€?was written by Byun, Young Min; Lee, Ji Min; Ryu, Ji Yeon; Go, Min Jeong; Na, Kyung Su; Kim, Youngjo; Lee, Junseong. Recommanded Product: (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-olThis research focused ontitanium hydroxyindanylaminopentenone complex preparation cycloaddition catalyst; crystal structure titanium hydroxyindanylaminopentenone. The article conveys some information:

New titanium complexes, TiLCl2(THF) and TiL2, containing the tridentate chiral Schiff-base ligand, L, prepared from the condensation reaction of 2,4-pentadione and (1R,2S)-(-)-1-aminoindanol, were synthesized and characterized by various anal. methods including X-ray crystallog. Ligand L acted as a dianionic tridentate ligand and, owing to a chiral center in the aminoindanol part, imparted chirality to its titanium complexes. The newly synthesized titanium complexes and previously reported analogous Ti complexes were used as catalysts in the cycloaddition of CO2 to propylene oxide as the first representatives of titanium complexes with tridentate Schiff base ligands to have been used for this purpose. These complexes provided high selectivity toward cyclic propylene carbonate (>99%) and showed considerable activities with TOF values up to 131 h-1 in comparison with the previously reported catalyst systems. After reading the article, we found that the author used (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol(cas: 126456-43-7Recommanded Product: (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol)

(1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol(cas: 126456-43-7) belongs to anime. Many important products require amines as part of their syntheses. Methylamine is utilized in the production of the analgesic meperidine (trade name Demerol) and the photographic developer Metol (trademark), and dimethylamine is used in the synthesis of the antihistamine diphenhydramine (trade name Benadryl), the solvent dimethylformamide (DMF), and the rocket propellant 1,1-dimethylhydrazine. The synthesis of the insect repellent N,N-diethyl-m-toluamide (DEET) incorporates diethylamine while that of the synthetic fibre Kevlar requires aromatic amines.Recommanded Product: (1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

《One-pot Synthesis of 4-Aminocyclohexanol Isomers by Combining a Keto Reductase and an Amine Transaminaseã€?was written by Sviatenko, Olha; Rios-Lombardia, Nicolas; Moris, Francisco; Gonzalez-Sabin, Javier; Venkata Manideep, Kollipara; Merdivan, Simon; Guenther, Sebastian; Suess, Philipp; Hoehne, Matthias. Recommanded Product: trans-4-AminocyclohexanolThis research focused ontransaminase ketoreductase aminocyclohexanol cascade enantioselective synthesis. The article conveys some information:

The efficient multifunctionalization by one-pot or cascade catalytic systems has developed as an important research field, but is often challenging due to incompatibilities or cross-reactivities of the catalysts leading to side product formation. Herein we report the stereoselective preparation of cis- and trans-4-aminocyclohexanol from the potentially bio-based precursor 1,4-cyclohexanedione. We identified regio- and stereoselective enzymes catalyzing reduction and transamination of the diketone, which can be performed in a one-pot sequential or cascade mode. For this, we identified regioselective keto reductases for the selective mono reduction of the diketone to give 4-hydroxycyclohexanone. The system is modular and by choosing stereocomplementary amine transaminases, both cis- and trans-4-aminocyclohexanol were synthesized with good to excellent diastereomeric ratios. Furthermore, we identified an amine transaminase that produces cis-1,4-cyclohexanediamine with diastereomeric ratios >98 : 2. These examples highlight that the high selectivity of enzymes enable short and stereoselective cascade multifunctionalizations to generate high-value building blocks from renewable starting materials. Introduction. In the experiment, the researchers used many compounds, for example, trans-4-Aminocyclohexanol(cas: 27489-62-9Recommanded Product: trans-4-Aminocyclohexanol)

trans-4-Aminocyclohexanol(cas: 27489-62-9) belongs to anime. Acylation is one of the most important reactions of primary and secondary amines; a hydrogen atom is replaced by an acyl group (a group derived from an acid, such as RCOOH or RSO3H, by removal of ―OH, such as RC(=O)â€? RS(O)2â€? and so on). Reagents may be acid chlorides (RCOC1, RSO2C1), anhydrides ((RCO)2O), or even esters (RCOORâ€?; the products are amides of the corresponding acids.Recommanded Product: trans-4-Aminocyclohexanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

《Olefin Epoxidation Catalyzed by Titanium-Salalen Complexes: Synergistic H2O2 Activation by Dinuclear Ti Sites, Ligand H-Bonding, and π-Acidityã€?was written by Engler, Hauke; Lansing, Markus; Gordon, Christopher P.; Neudoerfl, Joerg-M.; Schaefer, Mathias; Schloerer, Nils E.; Coperet, Christophe; Berkessel, Albrecht. Reference of 2-Hydroxyphenylboronic acidThis research focused ontitanium Salalen Complex catalyst preparation crystal structure Epoxidation DFT; oxidation kinetics titanium Salalen Complex catalyst. The article conveys some information:

Titanium-salalen complexes have recently solved a long-standing problem in homogeneous epoxidation catalysis by enabling the selective catalytic epoxidation of terminal, nonconjugated olefins with hydrogen peroxide. The authors disclose the mechanism of this intriguing catalyst system, based on XRD analyses, kinetic studies, and NMR elucidation of intermediate structures, complemented by DFT computations. Titanium-salalen catalysts are typically prepared/stored as bis-μ-oxo or μ-oxo-μ-peroxo dimers. Under reaction conditions, while the μ-oxo bridged catalyst dimers remain intact, the epoxidation occurs through an octahedral, yet altered, coordination geometry of the homochiral monomeric subunits. This catalytically active coordination mode is accessed by a slow pre-equilibrium, involving uptake of hydrogen peroxide, and subsequent rearrangement of the coordination sphere of the dinuclear complex. This configuration allows a three-pronged electrophilic activation of hydrogen peroxide, which enables oxygen transfer by the joint action of (i) the Lewis acidic titanium center, (ii) H-bond donation by the ligand’s NH, and (iii) π-chalcogen interaction with the ligand’s pentafluorophenyl moieties. This efficient activation of H2O2 by a dinuclear site parallels recent findings on the active sites of the industrial heterogeneous titanium silicalite TS-1 catalyst. The experimental part of the paper was very detailed, including the reaction process of 2-Hydroxyphenylboronic acid(cas: 89466-08-0Reference of 2-Hydroxyphenylboronic acid)

2-Hydroxyphenylboronic acid(cas: 89466-08-0) belongs to acyl phenylboronic acid. Phenylboronic acid (PBA), a synthetic molecule applied in RNA affinity chromatography, is able to form reversible covalent ester bonds with 1,2- or 1,3-cis-doils on the ribose ringReference of 2-Hydroxyphenylboronic acid

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

《Electrochemical performances of pyrolytic-cellulose for lithium and sodium ion batteries anodeã€?was written by Li, Lingfang; Chen, Dan; Su, Sichao; Zeng, Bin. Application of 54-17-1 And the article was included in Materials Express in 2020. The article conveys some information:

At present, due to the depletion of fossil fuels and increasingly serious environmental problems, more and more attention has been paid to the development and application of functional nanostructured materials as renewable energy storage materials. Herein, lithium and sodium storage properties of hard carbons (HC) prepared by pyrolyzing cellulose were investigated. The orderliness and bonding mode of hard carbon were analyzed by X-Ray Diffraction and XPS. Electrochem. properties were characterized by Cyclic Voltammetry, electrochem. Impedance Spectroscopy and charge-discharge test. Results showed that the cellulose-derived hard carbon had good lithium and sodium storage performance. The charge-discharge capacity was about 400 mAh/g and 240 mAh/g, resp., at a c.d. of 0.2 A/g, and capacity was also stable under high c.d. of 2 A/g. The experimental part of the paper was very detailed, including the reaction process of rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol(cas: 54-17-1Application of 54-17-1)

rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol(cas: 54-17-1) is oxidized in various tissues under either aerobic or anaerobic conditions through glycolysis; the oxidation reaction produces carbon dioxide, water, and ATP.Application of 54-17-1

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

《Bio-inspired drug-dominated supramolecular nanocomplex based on low molecular weight heparin for progressive tumor therapyã€?was written by Yu, Yao; Xu, Cheng; Zhen, Le; Yang, Shan; Zhou, Jianping; Yao, Jing. Recommanded Product: 3-Bromopropan-1-olThis research focused ontumor antitumor doxorubicin heparin; (KLAKLAK)(2) peptide; Anti-angiogenesis; Low molecular weight heparin; Mitochondrial damage; Supramolecular assembly. The article conveys some information:

Low mol. weight heparin (LMWH) is a natural sulfated glycosaminoglycan with the affinity to proangiogenic factors, rendering it a promising agent for tumor therapy. Inspired by DOX binding to the helix of DNA, mitochondrial damage KLA peptide derivative (mKLA) and anti-angiogenic LMWH-chrysin conjugate (LC) are constructed to simulate the double strands for doxorubicin (DOX) binding (LKD nanocomplex). Initiated and “”locked”” by DOX, mKLA and LC temporarily aggregate by π-π stacks, electrostatic and hydrophobic interactions in aqueous condition with self-amplified DOX loading (19.07 ± 1.08 wt%). During endosome-lysosome trafficking, DOX protonated by H+ could “”unlock”” the LKD nanocomplex to disassemble, which enables mKLA and DOX to damage mitochondria and nucleus DNA resp., and LMWH could also inhibit angiogenesis. Based on the strong inhibition of tumors at all stages in vivo, we hold that LKD nanocomplex provides a new opportunity based on smart construction of carbohydrate materials for clin. advanced cancer patients. In the experiment, the researchers used many compounds, for example, 3-Bromopropan-1-ol(cas: 627-18-9Recommanded Product: 3-Bromopropan-1-ol)

3-Bromopropan-1-ol(cas: 627-18-9) is used in the synthesis of fluorescent halide-sensitive quinolinium dyes, chiral, quaternary prolines through cyclization of quaternary amino acids and molten salt-polymers. It is utilized for the study of micellar media and in microemulsions based on cationic or a nonionic surfactant by reacting with phenols.Recommanded Product: 3-Bromopropan-1-ol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Application of 821-41-0In 2019 ,《Highly Performing Iodoperfluoroalkylation of Alkenes Triggered by the Photochemical Activity of Perylene Diimidesã€?was published in ChemPhotoChem. The article was written by Rosso, Cristian; Filippini, Giacomo; Cozzi, Pier Giorgio; Gualandi, Andrea; Prato, Maurizio. The article contains the following contents:

A novel efficient photochem. procedure for the direct iodoperfluoroalkylation of terminal olefins was developed. The process uses a simple and inexpensive perylenediimide (PDI) in an extremely low catalytic loading and occurs with visible light irradiation The methodol. was highly valuable from a synthetic point of view, since it proceeded under mild reaction conditions with a significant rate of production Preliminary mechanistic investigations were also reported. In the experiment, the researchers used 5-Hexen-1-ol(cas: 821-41-0Application of 821-41-0)

5-Hexen-1-ol(cas: 821-41-0) is used in cyclization to a tetrahydropyran by phenylselenoetherification. It is also used as a building block in synthetic chemistry.Application of 821-41-0

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Synthetic Route of C7H7BrOIn 2019 ,《Temperature responsive polymer-supported TEMPO: An efficient and recoverable catalyst for the selective oxidation of alcoholsã€?was published in Tetrahedron Letters. The article was written by Chen, Tao; Xu, Zhenkai; Zhou, Lei; Hua, Laiyu; Zhang, Shuo; Wang, Jiping. The article contains the following contents:

This study aimed to combine the advantages of homogeneous catalysis and heterogeneous catalysis by immobilizing TEMPO into a water-soluble temperature responsive polymer. The supported TEMPO was water soluble and displayed excellent activity in the selective oxidation of alcs. below the LCST and can be easily recovered. The results came from multiple reactions, including the reaction of (4-Bromophenyl)methanol(cas: 873-75-6Synthetic Route of C7H7BrO)

(4-Bromophenyl)methanol(cas: 873-75-6) undergoes three-component reaction with acetylferrocene and arylboronic acid to give ferrocenyl ketones containing biaryls.Synthetic Route of C7H7BrO It undergoes oxidation reaction in the presence of polyvinylpolypyrrolidone-supported hydrogen peroxide, silica sulfuric acid and ammonium bromide to yield 4-bromobenzaldehyde.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

《Synthesis of Dibenzofurans by Cu-Catalyzed Deborylative Ring Contraction of Dibenzoxaborinsã€?was published in Organic Letters in 2020. These research results belong to Sumida, Yuto; Harada, Ryu; Sumida, Tomoe; Johmoto, Kohei; Uekusa, Hidehiro; Hosoya, Takamitsu. Application of 89466-08-0 The article mentions the following:

An efficient transformation of dibenzoxaborins to dibenzofurans by deborylative ring contraction was achieved under mild conditions using a copper catalyst. The method showed a broad substrate scope enabling the preparation of various dibenzofurans, including those bearing a functional group. The ready availability of various dibenzoxaborins enhances the utility of this method, as demonstrated by the regiodivergent synthesis of dibenzofurans. The results came from multiple reactions, including the reaction of 2-Hydroxyphenylboronic acid(cas: 89466-08-0Application of 89466-08-0)

2-Hydroxyphenylboronic acid(cas: 89466-08-0) belongs to acyl phenylboronic acid. Phenylboronic acid (PBA) has been used to extract β-blockers (a class of aminoalcohol-containing drugs) from aqueous solution, rat, and human plasma. Application of 89466-08-0

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts