Tag: 100-200

Heterogeneous Catalysis for Oxidation of Alcohol via 1-Methyl-2-azaadamanane N-oxyl Immobilized on Magnetic Polystyrene Nanosphere was written by Guo, Xiaqun;Li, Meichao;Wang, Jianli;Li, Chunmei;Hu, Xinquan;Jin, Liqun;Sun, Nan;Hu, Baoxiang;Shen, Zhenlu. And the article was included in ChemistrySelect in 2022.Category: alcohols-buliding-blocks This article mentions the following:

A highly promising heterogeneous strategy was describedn in which a catalytic amount of 1-methyl-2-azaadamanane N-oxyl immobilized on magnetic polystyrene nanosphere (1-Me-AZADO/MPNs) was used and a series of carbonyl compounds were obtained from various alcs. in 73-99% isolated yields and high selectivity (>99%) under Anelli conditions, thus offering a greener and more convenient methods in the synthesis of carbonyl compounds The attractive features of convenient magnetic separation (within seconds), good recyclability (up to 20 runs) and fast reaction rates (5-20 min) were very efficient to improve the utility of azaadamantane-type-nitroxyl radicals in the oxygenation. In the experiment, the researchers used many compounds, for example, (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5Category: alcohols-buliding-blocks).

(1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Category: alcohols-buliding-blocks

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Total Synthesis and Structure Assignment of Saptomycin H was written by Shimura, Jun;Ando, Yoshio;Ohmori, Ken;Suzuki, Keisuke. And the article was included in Organic Letters in 2022.SDS of cas: 2216-51-5 This article mentions the following:

We report herein the first total synthesis of saptomycin H, by which the unidentified absolute stereochem. of the oxiranyl side chain has been determined as 14R, 16S. The keys include a concise assembly of three units, anthrone, sugar and side chain and AZADOL-mediated 6-endo selective pyranone (A-ring) formation. In the experiment, the researchers used many compounds, for example, (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5SDS of cas: 2216-51-5).

(1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.SDS of cas: 2216-51-5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Steric effects in the copper(II) chelates of 2-pyridyl alcohols was written by Lane, T. J.;Kandathil, A. J.;Rosalie, S. M.. And the article was included in Inorganic Chemistry in 1964.Computed Properties of C7H9NO This article mentions the following:

The acid dissociation constants of 2-pyridylcarbinol, 6-methyl-2-pyridylcarbinol, 2-(β-hydroxyethyl)pyridine, and 2-(β-hydroxyethyl)-6-methylpyridine and the stability constants of the Cu(II) chelates of these ligands were determined by the Calvin-Bjerrum (C. and Wilson, CA 40,285⁸; B., Metal Ammine Formation in Aqueous Solution: Theory of the Reversible Step Reactions, 1941(CA 35, 6206³)) potentiometric titration technique in 50 volume % 1,4-dioxane-water at 0, 15, and 25°. Enthalpy values were determined from direct calorimetric measurements as well as from the temperature dependence of the formation constants The results of the study show that the presence of the Me group in the 6-position decreases enthalpy and increases entropy, and the increase in entropy is not large enough to counteract the effects of steric hindrance. In the experiment, the researchers used many compounds, for example, 6-Methyl-2-pyridinemethanol (cas: 1122-71-0Computed Properties of C7H9NO).

6-Methyl-2-pyridinemethanol (cas: 1122-71-0) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Computed Properties of C7H9NO

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Degradation of fenitrothion in forest soil and effects on forest soil microbes was written by Spillner, Charles J.;DeBaun, Jack R.;Menn, Julius J.. And the article was included in Journal of Agricultural and Food Chemistry in 1979.Product Details of 60463-12-9 This article mentions the following:

Two forest soils were treated with ¹⁴C-ring-labeled fenitrothiony (I) [122-14-5] (7.4 ppm in wet soil) and held in a dark growth chamber at 30° for 50 days. Periodic sampling and anal. revealed that 50% degradation of I occurred in 3 days. The transient formation of 3-methyl-4-nitrophenol (MNP) [2581-34-2] and the formation of CO₂ and soil-bound ¹⁴C as terminal products were also established. Results were similar in both forest soils. After 50 days of incubation of the soils, the originally applied ¹⁴C was accounted for as I (3-6%), MNP (5-7%), 3-methyl-4-nitroanisole [5367-32-8] (4%), CO₂ (35%), and soil-bound ¹⁴C (48-50%). The bound ¹⁴C was associated mainly with humic acid and fulvic acid fractions. Minimal degradation occurred in sterilized soils, suggesting microbial activity was responsible for the observed degradation of I. Furthermore, the soil microflora were not qual. affected by I. From these studies I can be regarded as a readily degradable insecticide in forest soil which is not deleterious to the forest soil microflora. In the experiment, the researchers used many compounds, for example, 3-(Hydroxymethyl)-4-nitrophenol (cas: 60463-12-9Product Details of 60463-12-9).

3-(Hydroxymethyl)-4-nitrophenol (cas: 60463-12-9) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Product Details of 60463-12-9

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

The palladium/norbornene-catalyzed ortho-silylmethylation reaction: a practical protocol for ortho-functionalized one-carbon homologation of aryl iodides was written by Sui, Xianwei;Ding, Linlin;Gu, Zhenhua. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2016.Quality Control of Benzo[d][1,3]dioxol-4-ol This article mentions the following:

A palladium/norbornene-catalyzed ortho-silylmethylation reaction using of (iodomethyl)cyclohexyloxydimethylsilane as the electrophile was reported. The ((cyclohexyloxy)dimethylsilyl)methyl group was readily oxidized using the Fleming-Tamao process or by ceric ammonium nitrate to give benzylic alc. derivatives This method was successfully applied in a concise synthesis of a biaryl analog of schisandrins. In the experiment, the researchers used many compounds, for example, Benzo[d][1,3]dioxol-4-ol (cas: 69393-72-2Quality Control of Benzo[d][1,3]dioxol-4-ol).

Benzo[d][1,3]dioxol-4-ol (cas: 69393-72-2) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Quality Control of Benzo[d][1,3]dioxol-4-ol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Synthesis of N-heteroarenemethyl esters via C-C bond cleavage of acyl cyanides under transition metal-free conditions was written by Lai, Miao;Su, Fangyao;Hu, Jingyi;Wang, Mengzhuo;Zhao, Mingqin;Zhang, Ganlin. And the article was included in Frontiers in Chemistry (Lausanne, Switzerland) in 2021.Product Details of 118289-16-0 This article mentions the following:

A practical method to synthesize N-heteroaryl esters from N-heteroaryl methanols with acyl cyanides via C-C bond cleavage without using any transition metal is demonstrated here. The use of Na₂CO₃/15-crown-5 couple enables access to a series of N-heteroaryl esters in high efficiency. This protocol is operationally simple and highly environmentally benign producing only cyanides as byproducts. In the experiment, the researchers used many compounds, for example, 2-Bromopyridine-4-methanol (cas: 118289-16-0Product Details of 118289-16-0).

2-Bromopyridine-4-methanol (cas: 118289-16-0) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Product Details of 118289-16-0

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

α- and β-[Fe₂(μ-S^tBu)₂(S^tBu)₄]^2-: Coexistence of two bond-stretch isomers of a classical bitetrahedral metal chalcogenolate compound was written by Hammann, Bernd;Chen, Changneng;Floerke, Ulrich;Hauptmann, Ralf;Bill, Eckhard;Sinnecker, Sebastian;Henkel, Gerald. And the article was included in Angewandte Chemie, International Edition in 2006.Reference of 29364-29-2 This article mentions the following:

[Fe₂(S^tBu)₆]^2- shows a new form of isomerism. Besides the isomer of classical structure for [Fe₂(μ-S^tBu)₂(S^tBu)₄](NMe₄)₂ (1a) there is also a variant (1b) in which the central Fe₂S₂ rhomb is inverted and the Fe-S bonds are distinctly shorter. 1B can be regarded as a transition state during the inversion of the bridging S atoms of 1a that is stabilized by significant π interactions. In the experiment, the researchers used many compounds, for example, Sodium 2-methyl-2-propanethiolate (cas: 29364-29-2Reference of 29364-29-2).

Sodium 2-methyl-2-propanethiolate (cas: 29364-29-2) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Reference of 29364-29-2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Physicochemical properties and oxidative stability of corn oil in infrared-based and hot air-circulating cookers was written by Kim, YoonHa;Kim, Mi-Ja;Lee, JaeHwan. And the article was included in Food Science and Biotechnology in 2022.Related Products of 3391-86-4 This article mentions the following:

Corn oil was heated using an IR cooker, an air fryer, and a cooking oven at similar temperatures, and oxidative stability and physicochem. properties including moisture content, temperature change, the profile of headspace volatiles, formaldehyde and acetaldehyde of the heated oils were compared. Corn oil heated using the air fryer showed the lowest degree of oxidation, followed by that heated using the IR cooker and the cooking oven. However, the content of headspace volatiles in 120 min heated oil using the IR cooker was higher by 2.57 and 5.37 times than that in oil heated using the cooking oven and the air fryer, resp. The profiles of formaldehyde and acetaldehyde in oils showed patterns inconsistent with those of headspace volatile and oxidation parameters. Generally, the air fryer-treated oil underwent slow lipid oxidation, whereas oil from the IR cooker had more volatiles and imparted odor to foods. In the experiment, the researchers used many compounds, for example, Oct-1-en-3-ol (cas: 3391-86-4Related Products of 3391-86-4).

Oct-1-en-3-ol (cas: 3391-86-4) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Related Products of 3391-86-4

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Determination of volatile compounds in sesame oil and sesame flavor using headspace solid-phase microextraction and GC-MS was written by Qin, Zao;Yang, Ran;Gao, Gui-yuan;Huang, Ji-nian;Chen, Xiao-lan;Qu, Ling-bo. And the article was included in Shipin Kexue (Beijing, China) in 2012.Application In Synthesis of Benzo[d][1,3]dioxol-4-ol This article mentions the following:

The volatile composition of com. and laboratory-prepared sesame oil and two sesame flavor samples was analyzed by headspace solid phase microextraction (HS-SPME) coupled with gas chromatog.-mass spectrometry (GC-MS). Sesame flavor contained higher levels of volatile compounds such as pyrazines, furans, pyridines, ketones and phenols, which greatly contributed to the aroma of sesame oil. However, such compounds as 3,5-dimethyl-phenol, 3-methyl-1,2-cyclopentanedione, 2-hydroxy-3-methyl-2-cyclopenten-1-one, cyclooctane and 2-furfurylthiol were observed in sesame flavor but not in sesame oil. Thiazole and pyrrole were only detected in sesame oil but not in sesame flavor. In the experiment, the researchers used many compounds, for example, Benzo[d][1,3]dioxol-4-ol (cas: 69393-72-2Application In Synthesis of Benzo[d][1,3]dioxol-4-ol).

Benzo[d][1,3]dioxol-4-ol (cas: 69393-72-2) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Application In Synthesis of Benzo[d][1,3]dioxol-4-ol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Paths in the synthesis of 1,9,10-trimethoxy-2,3-methylendioxyaporphine was written by Vinogradova, V. I.;Yunusov, M. S.. And the article was included in Khimiya Prirodnykh Soedinenii in 1985.Safety of Benzo[d][1,3]dioxol-4-ol This article mentions the following:

Treating aldehyde I with NH₄OAc-AcOH in refluxing MeNO₂ gave 81% nitrostyrene II (R = CH:CHNO₂) which was reduced by LiAlH₄ in Et₂O to give 70% amine II (R = CH₂CH₂NH₂). The latter was treated with (2-bromo-4,5-dimethoxyphenyl)acetic acid to give tetrahydroisoquinoline III via Bischler-Napieralski cyclization, whose attempted photocyclization gave only 2-bromo-4,5-dimethoxybenzaldehyde and unreacted III. In the experiment, the researchers used many compounds, for example, Benzo[d][1,3]dioxol-4-ol (cas: 69393-72-2Safety of Benzo[d][1,3]dioxol-4-ol).

Benzo[d][1,3]dioxol-4-ol (cas: 69393-72-2) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Safety of Benzo[d][1,3]dioxol-4-ol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts