Cheng, Pengfei et al. published their research in Chemical Engineering Journal (Amsterdam, Netherlands) in 2022 | CAS: 10030-85-0

(2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal hydrate (cas: 10030-85-0) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Safety of (2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal hydrate

High cobalt exposure facilitates bioactive exopolysaccharides production with a novel molecular structure in Botryococcus braunii was written by Cheng, Pengfei;Chang, Ting;Wang, Chun;Yao, Changhong;Zhou, Chengxu;Liu, Tianzhong;Wang, Guangce;Yan, Xiaojun;Ruan, Roger. And the article was included in Chemical Engineering Journal (Amsterdam, Netherlands) in 2022.Safety of (2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal hydrate This article mentions the following:

The promising unicellular colonial Botryococcus braunii can secrete large amounts of bioactive exopolysaccharides. Our previous study revealed Botryococcus could tolerate high-concentrations of metallic cobalt, and extracellular hydrocarbons increased simultaneously. However, the characteristics of the extracellular polysaccharides (EPS) closely related to extracellular hydrocarbons is still unclear. This research focuses on the effects of cobalt exposure on the production, structure, and bioactivity of exopolysaccharides from colonial Botryococcus, aiming to provide a theor. clue on the potential contribution of EPS to the cobalt tolerance ability in this alga for cobalt bioremediation from the perspective of structure-bioactivity relationship. The results showed that high cobalt treatment (4.5 mg/L) exerted little influence on the growth of the alga, or the total carbohydrate content obtained, compared to the algae without cobalt treatment. EPSs of B. braunii SAG 30.81, under normal condition (EPS-Co) was mainly composed of glucose, mannose, fucose, galactose, rhamnose, and xylose, but also with the presence of sulfate substitutions, which was unique among the EPSs previously reported in this alga. Cobalt treatment resulted in a remarkable decline of rhamnose, and an increase of ribose and sulfate content, with more esterified uronic acids in the EPS (EPS + Co). EPS + Co, overall, had a larger but more compact and branched, spherical-like EPSs, with more ordered (helix) chains relative to EPS-Co. EPS + Co exhibited stronger antioxidant and antibacterial activity than EPS-Co, which could be attributed to the changed structural characteristics, such as the decrease of Rha, Fuc, and Gal and an increase of sulfate substitutions, uronic acids and Ara, more branched structure, and more ordered conformation. The enhanced antioxidant activity could be contributed to the alga tolerance to cobalt exposure, which was benefitted by cobalt bioremediation. In the experiment, the researchers used many compounds, for example, (2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal hydrate (cas: 10030-85-0Safety of (2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal hydrate).

(2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal hydrate (cas: 10030-85-0) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Safety of (2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal hydrate

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Caputo, Lucia et al. published their research in BMC Complementary Medicine and Therapies in 2022 | CAS: 499-75-2

5-Isopropyl-2-methylphenol (cas: 499-75-2) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.COA of Formula: C10H14O

Chemical composition, antibiofilm, cytotoxic, and anti-acetylcholinesterase activities of Myrtus communis L. leaves essential oil was written by Caputo, Lucia;Capozzolo, Francesca;Amato, Giuseppe;De Feo, Vincenzo;Fratianni, Florinda;Vivenzio, Giovanni;Nazzaro, Filomena. And the article was included in BMC Complementary Medicine and Therapies in 2022.COA of Formula: C10H14O This article mentions the following:

The potential of essential oils (EOs) and of their principal constituents for eradication of biofilm and at the same time the research of new potential acetylcholinesterase inhibitors is gaining increasing interest in last years. The aims of this study were to determine the chem. composition and to evaluate the antibacterial, cytotoxic, and anti-acetylcholinesterase properties of Myrtus communis leaves essential oil and its main constituents. Essential oil was obtained by hydrodistillation of M. communis L. leaves and was analyzed by GC and GC-MS. The antimicrobial activity was carried out against both gram-neg. and gram-pos. bacteria. The microdilution method was used to estimate the min. inhibitory concentrations (MICs). Then, the capacity of essential oil and its main constituent to inhibit biofilm growth, with the method of OToole and Kolterand, and the metabolic activity of biofilm cells through the MTT colorimetric method were evaluated at different times. Moreover, was studied the potential cytotoxic activity against SH-SY5Y cell line with MTT assay and the anti-acetylcholinesterase activity using Ellmans assay. Myrtenyl-acetate, 1,8 cineole, α-pinene, and linalool were the main components in the EO. The myrtle EO, at the min. tested dose (0.4 mg/mL), inhibited S. aureus biofilm by 42.1% and was capable of inhibiting the biofilm cell metabolism in all tested strains, except Staphylococcus aureus. Moreover, the EO showed good cytotoxic and anti-acetylcholinesterase activities IC50 of 209.1 and 32.8μg/mL, resp. The results suggest that myrtle EO and its main constituents could be used as possible products that could act against the resistant pathogenic species E. coli, P. aeruginosa, L. monocytogenes and S. aureus, on the other hand, as possible coadjutants in the treatment of neurol. diseases. In the experiment, the researchers used many compounds, for example, 5-Isopropyl-2-methylphenol (cas: 499-75-2COA of Formula: C10H14O).

5-Isopropyl-2-methylphenol (cas: 499-75-2) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.COA of Formula: C10H14O

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kageyuki, Ikuo et al. published their research in Organic Letters in 2017 | CAS: 1214264-88-6

2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-naphtho[1,8-de][1,3,2]diazaborinine (cas: 1214264-88-6) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.HPLC of Formula: 1214264-88-6

Copper-catalyzed B(dan)-installing carboboration of alkenes was written by Kageyuki, Ikuo;Osaka, Itaru;Takaki, Ken;Yoshida, Hiroto. And the article was included in Organic Letters in 2017.HPLC of Formula: 1214264-88-6 This article mentions the following:

Carboboration of alkenes was found to occur readily with an unsym. diboron [(pin)B-B(dan)] (H2dan = 1,8-naphthalenediamine) and alkyl halides under copper catalysis, leading to the direct formation of protected alkylboron compounds via synchronous C-C and C-B bond-forming processes. The B(dan) moiety was solely installed into the organic frameworks with the regioselective attachment to a terminal carbon of alkenes employed. In the experiment, the researchers used many compounds, for example, 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-naphtho[1,8-de][1,3,2]diazaborinine (cas: 1214264-88-6HPLC of Formula: 1214264-88-6).

2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-naphtho[1,8-de][1,3,2]diazaborinine (cas: 1214264-88-6) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.HPLC of Formula: 1214264-88-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wang, Suhua et al. published their research in Journal of Medicinal Chemistry in 2017 | CAS: 1777-82-8

(2,4-Dichlorophenyl)methanol (cas: 1777-82-8) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Electric Literature of C7H6Cl2O

Discovery of 1,4-Benzodiazepine-2,5-dione (BZD) Derivatives as Dual Nucleotide Binding Oligomerization Domain Containing 1/2 (NOD1/NOD2) Antagonists Sensitizing Paclitaxel (PTX) To Suppress Lewis Lung Carcinoma (LLC) Growth in Vivo was written by Wang, Suhua;Yang, Jingshu;Li, Xueyuan;Liu, Zijie;Wu, Youzhen;Si, Guangxu;Tao, Yiran;Zhao, Nan;Hu, Xiao;Ma, Yao;Liu, Gang. And the article was included in Journal of Medicinal Chemistry in 2017.Electric Literature of C7H6Cl2O This article mentions the following:

Nucleotide-binding oligomerization domain-like receptors (NLRs) are intracellular sensors of pathogen-associated mol. patterns (PAMPs) and damage-associated mol. patterns (DAMPs). Previously, we reported nucleotide-binding oligomerization domain-containing protein 1 (NOD1) antagonists (11, 12) and a NOD2 antagonist (9) that sensitized docetaxel (DTX) or paclitaxel (PTX) treatment for breast or lung cancer. In this article, we describe for the first time a 1,4-benzodiazepine-2,5-dione (BZD) derivative (26bh) that acts as a dual NOD1/NOD2 antagonist and inhibits both nuclear factor κB (NF-κB) and mitogen-activated protein kinase (MAPK) inflammatory signaling, thereby sensitizing PTX to suppress Lewis lung carcinoma (LLC) growth. After investigation of the compound’s cytotoxicity, a systematic structure-activity relationship (SAR) was completed and revealed several key factors that were necessary to maintain antagonistic ability. This study establishes the possibility for using adjuvant treatment to combat cancer by antagonizing both NOD1 and NOD2 signaling. In the experiment, the researchers used many compounds, for example, (2,4-Dichlorophenyl)methanol (cas: 1777-82-8Electric Literature of C7H6Cl2O).

(2,4-Dichlorophenyl)methanol (cas: 1777-82-8) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Electric Literature of C7H6Cl2O

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Monari, Stefania et al. published their research in PLoS One in 2021 | CAS: 10083-24-6

(E)-4-(3,5-Dihydroxystyryl)benzene-1,2-diol (cas: 10083-24-6) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Recommanded Product: 10083-24-6

Phytochemical characterization of raw and cooked traditionally consumed alimurgic plants was written by Monari, Stefania;Ferri, Maura;Montecchi, Beatrice;Salinitro, Mirko;Tassoni, Annalisa. And the article was included in PLoS One in 2021.Recommanded Product: 10083-24-6 This article mentions the following:

In the past, wild edible alimurgic plants became an important alternative food source when poverty, wars or drought made it difficult to access crops. These plants were considered rich in highly nutritional compounds and also frequently used as food-medicine given their health-promoting properties. With the aim of improving our knowledge on the content of beneficial or detrimental compounds in relation with past local dietary and curative traditions, 12 wild food plant species were collected from two study areas selected for their very different degree of industrialization, urbanization, and conservation of local past traditions among the population: the Bologna province (Northern Italy) and the Middle Agri Valley (Southern Italy). Protein, polyphenol flavonoid and biogenic amine (both free and conjugated) contents and antioxidant activity of raw and boiled wild food plant extracts, and of cooking water were analyzed by means of spectrophotometric and high-performance liquid chromatog. methods. The results demonstrated that most of the phenolic compounds were released in the cooking water which also showed the highest antioxidant activity. Seventeen different phenolic compounds were identified, of which the health-related luteolin, luteolin-7-glucoside and rutin were the most abundant (e.g., S. pratensis L. and C. intybus L.). On the other hand, biogenic amines were absent or present at very low levels in cooking water of those very same species (e.g., S. pratensis L., T. officinalis Weber, C. vesicaria subsp. taraxacifolia and C. intybus L.) of which traditionally a decoction is used for therapeutic purposes. Free and conjugated spermidine and spermine were generally the most abundant biogenic amines, while none of the known detrimental monoamines (e.g., histamine) was detected. In conclusion, the present results seem to support past local popular traditions which indicated beneficial medical properties of some wild edible plant, as well as of their cooking water. In the experiment, the researchers used many compounds, for example, (E)-4-(3,5-Dihydroxystyryl)benzene-1,2-diol (cas: 10083-24-6Recommanded Product: 10083-24-6).

(E)-4-(3,5-Dihydroxystyryl)benzene-1,2-diol (cas: 10083-24-6) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Recommanded Product: 10083-24-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Adil, Syed Farooq et al. published their research in Catalysts in 2020 | CAS: 1777-82-8

(2,4-Dichlorophenyl)methanol (cas: 1777-82-8) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Reference of 1777-82-8

Eco-friendly mechanochemical preparation of Ag2O-MnO2/graphene oxide nanocomposite: an efficient and reusable yst for the base-free, aerial oxidation of alcohols was written by Adil, Syed Farooq;Assal, Mohamed E.;Khan, Mujeeb;Shaik, Mohammed Rafi;Kuniyil, Mufsir;Sekou, Doumbia;Dewidar, Ahmed Z.;Al-Warthan, Abdulrahman;Siddiqui, Mohammed Rafiq H.. And the article was included in Catalysts in 2020.Reference of 1777-82-8 This article mentions the following:

Recently, the development of eco-friendly mechanochem. approaches for the preparation of novel ysts with enhanced activity and selectivity has gained considerable attention. Herein, we developed a rapid and solvent-less mechanochem. method for the preparation of mixed metal oxide (Ag2O-MnO2) decorated graphene oxide (GRO)-based nanocomposites (Ag2O-MnO2/(X weight%)GRO), as the Ag2O-MnO2/(X weight%)GRO nanocomposite was fabricated by the phys. grinding of freshly prepared GRO and pre-annealed (300°C) mixed metal oxide nanoparticles (NPs) (Ag2O-MnO2) using an eco-friendly milling procedure. The as-prepared nanoysts were characterized by using various techniques. Furthermore, the nanocomposites were applied as a heterogeneous yst for the oxidation of alc. by employing gaseous O2 as an eco-friendly oxidant under base-free conditions. The mechanochem. obtained GRO-based composite exhibited noticeable enhancement in the surface area and ytic performance compared to the pristine Ag2O-MnO2. The results revealed that (1%)Ag2O-MnO2/(5 weight%)GRO yst exhibited higher specific performance (13.3 mmol.g-1.h-1) with a 100% conversion of benzyl alc. (BnOH) and >99% selectivity towards benzaldehyde (BnH) within 30 min. The enhancement of the activity and selectivity of GRO-based nanoyst was attributed to the presence of various oxygen-containing functional groups, a large number of defects, and a high sp. surface area of GRO. In addition, the as-prepared nanoyst also demonstrated excellent ytic activity towards the conversion of a variety of other alcs. to resp. carbonyls under optimal conditions. Besides, the yst ((1%)Ag2O-MnO2/(5 weight%)GRO) could be efficiently recycled six times with no noticeable loss in its performance and selectivity. In the experiment, the researchers used many compounds, for example, (2,4-Dichlorophenyl)methanol (cas: 1777-82-8Reference of 1777-82-8).

(2,4-Dichlorophenyl)methanol (cas: 1777-82-8) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Reference of 1777-82-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhang, Xiaoming et al. published their research in Journal of Agricultural and Food Chemistry in 2022 | CAS: 499-75-2

5-Isopropyl-2-methylphenol (cas: 499-75-2) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Application of 499-75-2

Synthesis, Antifungal Activity, and 3D-QASR of Novel 1,2,3,4-Tetrahydroquinoline Derivatives Containing a Pyrimidine Ether Scaffold as Chitin Synthase Inhibitors was written by Zhang, Xiaoming;Yang, Zhaokai;Xu, Huan;Liu, Yuansheng;Yang, Xinling;Sun, Tengda;Lu, Xingxing;Shi, Fasheng;Yang, Qing;Chen, Wei;Duan, Hongxia;Ling, Yun. And the article was included in Journal of Agricultural and Food Chemistry in 2022.Application of 499-75-2 This article mentions the following:

The introduction of active groups of natural products into the framework of pesticide mols. is an effective approach for discovering active lead compounds, and thus has been widely used in the development of new agrochems. In this work, a novel series of 1,2,3,4-tetrahydroquinoline derivatives containing a pyrimidine ether scaffold were designed and synthesized by the active substructure splicing method. The new compounds showed good antifungal activities against several fungi. Especially, compound (I) displayed excellent in vitro activity against Valsa mali and Sclerotinia sclerotiorum with EC50 values of 0.71 and 2.47 μg/mL, resp. I had slightly stronger inhibitory activity (68.08% at 50 μM) against chitin synthase (CHS) than that of polyoxin D (63.84% at 50 μM) and exhibited obvious curative and protective effects on S. sclerotiorumin vivo. Thus, I can be considered as a new candidate fungicide as a chitin synthase inhibitor. An accurate and reliable three-dimensional quant. structure-activity relationship (3D-QSAR) model presented a useful direction for the further excogitation of more highly active fungicides. Mol. docking revealed that the conventional hydrogen bond mainly affected the binding affinity of I with chitin synthase. The present results will provide a guidance to discover potential CHS-based fungicides for plant disease control in agriculture. In the experiment, the researchers used many compounds, for example, 5-Isopropyl-2-methylphenol (cas: 499-75-2Application of 499-75-2).

5-Isopropyl-2-methylphenol (cas: 499-75-2) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Application of 499-75-2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Li, Chao et al. published their research in Molecules in 2022 | CAS: 2216-51-5

(1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Quality Control of (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol

Discrimination and Characterization of the Volatile Organic Compounds in Schizonepetae Spica from Six Regions of China Using HS-GC-IMS and HS-SPME-GC-MS was written by Li, Chao;Wan, Huiying;Wu, Xinlong;Yin, Jiaxin;Zhu, Limin;Chen, Hanjiang;Song, Xinbo;Han, Lifeng;Yang, Wenzhi;Yu, Heshui;Li, Zheng. And the article was included in Molecules in 2022.Quality Control of (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol This article mentions the following:

Volatile organic compounds (VOCs) are the main chem. components of Schizonepetae Spica (SS), which have pos. effects on the quality evaluation of SS. In this study, HS-SPME-GC-MS (headspace solid-phase microextraction-gas chromatog.-mass spectrometry) and HS-GC-IMS (headspace-gas chromatog.-ion mobility spectrometry) were performed to characterize the VOCs of SS from six different regions. A total of 82 VOCs were identified. In addition, this work compared the suitability of two instruments to distinguish SS from different habitats. The regional classification using orthogonal partial least squares discriminant anal. (OPLS-DA) shows that the HS-GC-IMS method can classify samples better than the HS-SPME-GC-MS. This study provided a reference method for identification of the SS from different origins. In the experiment, the researchers used many compounds, for example, (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5Quality Control of (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol).

(1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Quality Control of (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ananthan, Subramaniam et al. published their research in Journal of Medicinal Chemistry in 2014 | CAS: 79651-64-2

(6-Aminopyridin-2-yl)methanol (cas: 79651-64-2) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Related Products of 79651-64-2

Design, Synthesis, and Structure-Activity Relationship Studies of a Series of [4-(4-Carboxamidobutyl)]-1-arylpiperazines: Insights into Structural Features Contributing to Dopamine D3 versus D2 Receptor Subtype Selectivity was written by Ananthan, Subramaniam;Saini, Surendra K.;Zhou, Guangyan;Hobrath, Judith V.;Padmalayam, Indira;Zhai, Ling;Bostwick, J. Robert;Antonio, Tamara;Reith, Maarten E. A.;McDowell, Shea;Cho, Eunie;McAleer, Leah;Taylor, Michelle;Luedtke, Robert R.. And the article was included in Journal of Medicinal Chemistry in 2014.Related Products of 79651-64-2 This article mentions the following:

(Aroylaminobutyl)arylpiperazines such as I were prepared as antagonists or partial agonists of the dopamine D3 receptor selective for D3 receptors over the related dopamine D2 receptors for potential use in treatment of drug addiction and schizophrenia. The calculated lipophilicities of and inhibition of dopamine D3 and D2 receptors by (aroylaminobutyl)arylpiperazines was determined, and the inhibition of mutant and chimeric D3 receptors by selected compounds and the activities of selected compounds in functional assays in human cells were determined Mol. docking calculations of the structures of selected compounds bound to dopamine D3 receptors were performed; the mol. docking studies and evaluation against a set of chimeric and mutant receptors suggest that interactions at the extracellular end of TM7 contribute to the selectivity of the ligands for dopamine D3 receptors over dopamine D2 receptors. In the experiment, the researchers used many compounds, for example, (6-Aminopyridin-2-yl)methanol (cas: 79651-64-2Related Products of 79651-64-2).

(6-Aminopyridin-2-yl)methanol (cas: 79651-64-2) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Related Products of 79651-64-2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Forbes, Diane C. et al. published their research in ACS Nano in 2014 | CAS: 109-17-1

((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(2-methylacrylate) (cas: 109-17-1) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Product Details of 109-17-1

Polycationic Nanoparticles for siRNA Delivery: Comparing ARGET ATRP and UV-Initiated Formulations was written by Forbes, Diane C.;Peppas, Nicholas A.. And the article was included in ACS Nano in 2014.Product Details of 109-17-1 This article mentions the following:

In this work, we develop and evaluate polycationic nanoparticles for the delivery of small interfering RNA (siRNA). Delivery remains a major challenge for translating siRNA to the clinic, and overcoming the delivery challenge requires effective siRNA delivery vehicles that meet the demands of the specific delivery strategy. Crosslinked polycationic nanoparticle formulations were synthesized using ARGET ATRP or UV-initiated polymerization The one-step, one-pot, surfactant-stabilized monomer-in-water synthesis technique may provide a simpler and faster alternative to complicated, multistep techniques and an alternative to methods that rely on toxic organic solvents. The polymer nanoparticles were synthesized using the cationic monomer 2-(diethylamino)ethyl methacrylate, the hydrophobic monomer tert-Bu methacrylate to tune pH responsiveness, the hydrophilic monomer poly(ethylene glycol) Me ether methacrylate to improve biocompatibility, and crosslinking agent tetraethylene glycol dimethacrylate to enhance colloidal stability. Four formulations were evaluated for their suitability as siRNA delivery vehicles in vitro with the human embryonic kidney cell line HEK293T or the murine macrophage cell line RAW264.7. The polycationic nanoparticles demonstrated efficient and rapid loading of the anionic siRNA following complexation. Confocal microscopy as well as flow cytometry anal. of cells treated with polycationic nanoparticles loaded with fluorescently labeled siRNA demonstrated that the polycationic nanoparticles promoted cellular uptake of fluorescently labeled siRNA. Knockdown experiments using polycationic nanoparticles to deliver siRNA demonstrated evidence of knockdown, thus demonstrating potential as an alternative route to creating polycationic nanoparticles. In the experiment, the researchers used many compounds, for example, ((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(2-methylacrylate) (cas: 109-17-1Product Details of 109-17-1).

((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(2-methylacrylate) (cas: 109-17-1) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Product Details of 109-17-1

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts