Alcohols-buliding-blocks

Practical imidazole-based phosphine ligands for selective palladium-catalyzed hydroxylation of aryl halides was written by Schulz, Thomas;Torborg, Christian;Schaeffner, Benjamin;Huang, Jun;Zapf, Alexander;Kadyrov, Renat;Boerner, Armin;Beller, Matthias. And the article was included in Angewandte Chemie, International Edition in 2009.Name: 4-Hydroxy-3-methylbenzonitrile This article mentions the following:

Novel imidazole-based phosphine ligands are synthesized on scales up to 100 g by a convenient lithiation-phosphorylation method. The phosphines are stable towards air and moisture and are successfully applied as ligands in the palladium-catalyzed selective hydroxylation of aryl halides. In the experiment, the researchers used many compounds, for example, 4-Hydroxy-3-methylbenzonitrile (cas: 15777-70-5Name: 4-Hydroxy-3-methylbenzonitrile).

4-Hydroxy-3-methylbenzonitrile (cas: 15777-70-5) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Name: 4-Hydroxy-3-methylbenzonitrile

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Salmonella Heidelberg side-step gene loss of respiratory requirements in chicken infection model was written by Goes, Vinicius;Monte, Daniel F. M.;Saraiva, Mauro de Mesquita Souza;Maria de Almeida, Adriana;Cabrera, Julia Memrava;Rodrigues Alves, Lucas Bocchini;Ferreira, Taisa Santiago;Lima, Tulio Spina de;Benevides, Valdinete P.;Barrow, Paul A.;Freitas Neto, Oliveiro Caetano de;Berchieri, Angelo Jr. And the article was included in Microbial Pathogenesis in 2022.SDS of cas: 57-55-6 This article mentions the following:

Among the important recent observations involving anaerobic respiration was that an electron acceptor produced as a result of an inflammatory response to Salmonella Typhimurium generates a growth advantage over the competing microbiota in the lumen. In this regard, anaerobically, salmonellae can oxidize thiosulfate (S2O2-3) converting it into tetrathionate (S4O2-6), the process by which it is encoded by ttr gene cluster (ttrSRttrBCA). Another important pathway under aerobic or anaerobic conditions is the 1,2-propanediol-utilization mediated by the pdu gene cluster that promotes Salmonella expansion during colitis. Therefore, we sought to compare in this study, whether Salmonella Heidelberg strains lacking the ttrA, ttrApduA, and ttrACBSR genes experience a disadvantage during cecal colonization in broiler chicks. In contrast to expectations, we found that the gene loss in S. Heidelberg potentially confers an increase in fitness in the chicken infection model. These data argue that S. Heidelberg may trigger an alternative pathway involving the use of an alternative electron acceptor, conferring a growth advantage for S. Heidelberg in chicks. In the experiment, the researchers used many compounds, for example, 1,2-Propanediol (cas: 57-55-6SDS of cas: 57-55-6).

1,2-Propanediol (cas: 57-55-6) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.SDS of cas: 57-55-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chitosan nanocomposite incorporated Satureja kermanica essential oil and extract: Synthesis, characterization and antifungal assay was written by Payandeh, Maryam;Ahmadyousefi, Mehdi;Alizadeh, Hamidreza;Zahedifar, Mahboobeh. And the article was included in International Journal of Biological Macromolecules in 2022.Safety of 5-Isopropyl-2-methylphenol This article mentions the following:

The present study reports the design, synthesis, and characterization of nanoencapsulated Satureja kermanica essential oil/extract by chitosan biopolymer (SKEO-CSN)/(SKEX-CSN) for the antifungal efficacy against Fusarium oxysporum, Alternaria alternata, Botrytis cinerea, Sclerotinia sclerotiorum, Rhizoctonia solani, and Pythium aphanidermatum. The prepared SKEO-CSN and SKEX-CSN were characterized by Fourier transform IR (FTIR), SEM (SEM), transmission electron microscopy (TEM), thermogravimetric anal. (TGA), and X-ray diffraction anal. (XRD). GC-Mass anal. was done to identify Satureja kermanica essential oil chem. compounds (SKEO). Thirty-five different components were detected from GC-MS anal. Thymol (46.54 %), and Carvacrol (30.54 %) were demonstrated as major compounds Antifungal studies showed that the SKEO-CSN and SKEX-CSN formulation effectively inhibit fungal growth more than free SKEO and SKEX. According to the results, SKEO-CSN and SKEX-CSN provide a wide range of promising antifungal effects and can be applied as an efficient green strategy to protect plants from fungus infections. In the experiment, the researchers used many compounds, for example, 5-Isopropyl-2-methylphenol (cas: 499-75-2Safety of 5-Isopropyl-2-methylphenol).

5-Isopropyl-2-methylphenol (cas: 499-75-2) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Safety of 5-Isopropyl-2-methylphenol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Synthesis of a New Polydentate Ligand Obtained by Coupling 2,6-Bis(imino)pyridine and (Imino)pyridine Moieties and Its Use in Ethylene Oligomerization in Conjunction with Iron(II) and Cobalt(II) Bis-halides was written by Bianchini, Claudio;Giambastiani, Giuliano;Guerrero Rios, Itzel;Meli, Andrea;Oberhauser, Werner;Sorace, Lorenzo;Toti, Alessandro. And the article was included in Organometallics in 2007.Category: alcohols-buliding-blocks This article mentions the following:

In this paper are described the synthesis, characterization, and coordinating properties of a new potentially pentadentate nitrogen ligand, ^CyAr2N₅ (I), that combines in the same mol. structure 2,6-bis(imino)pyridine and (imino)pyridine moieties. This ligand reacts with 1 or 2 equiv of anhydrous MCl₂ (M = Fe, Co) to give paramagnetic mononuclear or homodinuclear complexes of the formula ^CyAr2N₅MCl₂ and ^CyAr2N₅M₂Cl₄. In the dinuclear complexes, one metal center is five-coordinate, while the other is four-coordinate. Ligand and metal complexes were characterized, both in the solid state and in solution, by a variety of techniques, including single-crystal x-ray diffraction analyses, magnetic susceptibility determinations, IR, visible-NIR, ¹H NMR, and X-band EPR spectroscopies. On activation by methylaluminoxane (MAO) in toluene, the Fe^II and Co^II complexes generate effective catalysts for the oligomerization of ethylene to 伪-olefins with productivities and Schulz-Flory parameters depending on the type and number of the coordinated metals. In an attempt to rationalize the surprisingly high activity of the Co^II precursors, and in particular that of the dinuclear derivative ^CyAr2N₅Co₂Cl₄, which is 4 times higher than that of the mononuclear analog ^CyAr2N₅CoCl₂, a Co^II complex was synthesized where the supporting ligand is sterically similar to ^CyAr2N₅, yet it contains only the three nitrogen donor atoms of the 2,6-bis(imino)pyridine moiety. All five nitrogen atoms of ^CyAr2N₅ play an active role under catalytic conditions, even when the precursor contains a free (imino)pyridine moiety. In the experiment, the researchers used many compounds, for example, 2-Bromo-6-(2-methyl-1,3-dioxolan-2-yl)pyridine (cas: 49669-14-9Category: alcohols-buliding-blocks).

2-Bromo-6-(2-methyl-1,3-dioxolan-2-yl)pyridine (cas: 49669-14-9) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Category: alcohols-buliding-blocks

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Use of Stille-type cross-coupling as a route to oligopyridylimines was written by Champouret, Yohan D. M.;Chaggar, Rajinder K.;Dadhiwala, Ishaq;Fawcett, John;Solan, Gregory A.. And the article was included in Tetrahedron in 2006.Related Products of 49669-14-9 This article mentions the following:

Tributylstannylpyridinyldioxolanes I (R = H, Me) are prepared; Stille coupling of I with bromopyridines in the presence of tetrakis(triphenylphosphine)palladium(0) followed by acid hydrolysis provides oligopyridinecarboxaldehydes and acetyloligopyridines such as II (R = H, Me) which are converted to arylimines such as III (R = H, Me; R¹ = Me₂CH). Lithiation of 2-(6-bromo-2-pyridinyl)-1,3-dioxolanes followed by alkylation with chlorotributylstannnane provides I (R = H, Me) in 88-92% yields. Stille coupling of I (R = H, Me) with bromopyridines such as 6,6′-dibromo-2,2′-bipyridine in the presence of tetrakis(triphenylphosphine)palladium(0) followed by hydrolysis with hydrochloric acid and neutralization provides oligopyridines such as quaterpyridines II (R = H, Me) in 45-80% yields; attempts to prepare a quinquepyridinedicarboxaldehyde by the same procedure yielded no isolable product because of the insolubility of the product formed upon deprotection. Aldehydes undergo condensation with 2,6-diisopropylaniline in ethanol in the presence of acetic acid to yield oligopyridineimines such as III (R = H; R¹ = Me₂CH), while acetyloligopyridines undergo condensation with 2,6-diisopropylaniline under solvent-free conditions at 160掳 in the presence of formic acid to yield imines such as III (R = Me; R¹ = Me₂CH). Crystal structures of III (R = H; R¹ = Me₂CH) and two other oligopyridylimines are determined by X-ray crystallog. In the experiment, the researchers used many compounds, for example, 2-Bromo-6-(2-methyl-1,3-dioxolan-2-yl)pyridine (cas: 49669-14-9Related Products of 49669-14-9).

2-Bromo-6-(2-methyl-1,3-dioxolan-2-yl)pyridine (cas: 49669-14-9) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Related Products of 49669-14-9

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ensiling and thermic treatment effects on nutrient content, protein solubility, and in vitro fermentation of partial crop faba beans was written by Bachmann, M.;Okon, P.;Blunk, C.;Kuhnitzsch, C.;Martens, S. D.;Steinhoefel, O.;Zeyner, A.. And the article was included in Animal Feed Science and Technology in 2022.Computed Properties of C3H8O2 This article mentions the following:

Legumes such as faba beans have a great potential to create local, independent, and high-quality protein resources for ruminant nutrition. Suitable methods for cost- and energy-effective preservation and protein stabilization against rapid fermentation in the rumen play an important role. Partial crop faba beans harvested with 500 or 708 g dry matter (DM)/kg were ensiled, toasted (160掳C, 60 min), or ensiled and toasted and it was investigated how this affects nutrient composition, protein solubility, carbohydrate fermentation, and in vitro organic matter digestibility (IVOMD). Non-protein nitrogen (NPN) concentrations increased and true protein (TP) concentrations decreased after ensiling, depending strongly on DM concentration of the plant (i.e., on maturity) – in NPN, from 15% to 35% (P < 0.001) and from 16% to 21% of crude protein (CP) (P > 0.05), and in TP, from 85% to 65% and from 83% to 79% of CP with 500 and 708 g DM/kg, resp. (P > 0.05) – whereas concentrations of soluble protein did not increase as much as expected. Toasting reduced soluble protein concentration in native faba beans from 56% to 29% and from 54% to 40% of CP with 500 and 708 g DM/kg, resp. (P < 0.001) and in ensiled faba beans from 58% to 38% and from 60% to 34% of CP with 500 and 708 g DM/kg, resp., compared to the native material (P < 0.001). Ensiling and toasting slightly affected other crude nutrient or metabolizable energy concentrations, carbohydrate fermentation, and IVOMD. In the experiment, the researchers used many compounds, for example, 1,2-Propanediol (cas: 57-55-6Computed Properties of C3H8O2).

1,2-Propanediol (cas: 57-55-6) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Computed Properties of C3H8O2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Metabolomics insights into the mechanism by which Epichloe gansuensis endophyte increased Achnatherum inebrians tolerance to low nitrogen stress was written by Hou, Wenpeng;Wang, Jianfeng;Christensen, Michael J.;Liu, Jie;Zhang, Yongqiang;Liu, Yinglong;Cheng, Chen. And the article was included in Plant and Soil in 2021.Related Products of 10083-24-6 This article mentions the following:

Epichloe gansuensis increases the tolerance of host plants to abiotic stress. However, little is known about the mechanism by which E. gansuensis improves grass growth under low nitrogen availability stress. Achnatherum inebrians with E. gansuensis (E+) and without E. gansuensis (E-) were treated with modified 1/2 Hoagland containing 0.01 mM (low N) or 7.5 mM N (normal level) for 18 wk. After 18 wk of treatment with N, the dry weight of E+ and E- plants were measured, and the metabolomics anal. of leaves and roots grown under two different N concentrations was conducted with GS-MS to determine differential metabolites and metabolic pathways. E+ A. inebrians had higher dry weight of leaves and roots compared to the E- A. inebrians under low N stress. E. gansuensis increased the tolerance of A. inebrians to low N stress by its capability to increase the content of organic acids (salicylic acid and 3-hydroxypropionic acid) and glucose-6-phosphate in leaves, and E. gansuensis increased the content of fatty acids (linolenic acid and oleic acid) and amino acids (glycine and 4-aminobutyric acid) in roots under low N stress. Finally, E. gansuensis reprogramed the metabolic pathway of amino acids of host grasses to adapt to the different N concentration Our results reveal the chem. mechanism by which E. gansuensis enhances the tolerance of host grasses to low N, and provide the theor. basis for utilizing E. gansuensis, improving of grasses and crops, and for developing new germplasm for low-N tolerant grasses. In the experiment, the researchers used many compounds, for example, (E)-4-(3,5-Dihydroxystyryl)benzene-1,2-diol (cas: 10083-24-6Related Products of 10083-24-6).

(E)-4-(3,5-Dihydroxystyryl)benzene-1,2-diol (cas: 10083-24-6) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Related Products of 10083-24-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Novel deep eutectic solvent-based liquid phase microextraction for the extraction of estrogenic compounds from environmental samples was written by Fattahi, Nazir;Shamsipur, Mojtaba;Nematifar, Ziba;Babajani, Nasrin;Moradi, Masoud;Soltani, Shahin;Akbari, Shahram. And the article was included in RSC Advances in 2022.Application of 2216-51-5 This article mentions the following:

Steroid hormones, such as estrone (E1), 17尾-estradiol (E2), 17尾-ethinylestradiol (EE2) and estriol (E3) are a group of lipophilic active substances, synthesized biol. from cholesterol or chem. A pH-switchable hydrophobic deep eutectic solvent-based liquid phase microextraction (DES-LPME) technique was established and combined with gas chromatog.-mass spectroscopy for the determination of estrogenic compounds in environmental water and wastewater samples. A DES was synthesized using l-menthol as HBA and (1S)-(+)-camphor-10-sulfonic acid (CSA) as HBD, and used as a green extraction solvent. By adjusting the pH of the solution, the unique behavior of the DES in the phase transition and extraction of the desired analytes was investigated. The homogenization process of the mixture is done only by manual shaking in less than 30 s and the phase separation is done only by changing the pH and without centrifugation. Some effective parameters on the extraction and derivatization, such as molar ratio of DES components, DES volume, KOH concentration, HCl volume, salt addition, extraction and derivatization time and derivatization prior or after extraction were studied and optimized. Under the optimum conditions, relative standard deviation (RSD) values for intra-day and inter-day of the method based on 7 replicate measurements of 20 ng L-1 of estrogenic compounds and 10 ng L-1 for internal standard in different samples were in the range of 2.2-4.6% and 3.9-5.7%, resp. The calibration graphs were linear in the range of 0.5-100 ng L-1 and the limits of detection (LODs) were in the range of 0.2-1.0 ng L-1. The relative recoveries of environmental water and wastewater samples which have been spiked with different levels of target compounds were 91.0-108.8%. In the experiment, the researchers used many compounds, for example, (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5Application of 2216-51-5).

(1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R鈥昈鈭?. For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Application of 2216-51-5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

A reusable MOF supported single-site nickel-catalyzed direct N-alkylation of anilines with alcohols was written by Lu, Yuanyuan;Chai, Huining;Yu, Kun;Huang, Chaonan;Li, Yujie;Wang, Jinyu;Ma, Jiping;Tan, Weiqiang;Zhang, Guangyao. And the article was included in Tetrahedron in 2022.Quality Control of (4-Chlorophenyl)methanol This article mentions the following:

A highly selective and reusable Ni(II)-bipyridine-based metal-organic framework (MOF) catalyst was designed for direct N-alkylation of amines with alcs. through a borrowing hydrogen (BH) strategy. This earth-abundant metal-based metal-organic framework catalyst significantly outperforms its homogeneous analogs and is reusable for at least up to 4 cycles without significant decrease in the yield of the target product. In the experiment, the researchers used many compounds, for example, (4-Chlorophenyl)methanol (cas: 873-76-7Quality Control of (4-Chlorophenyl)methanol).

(4-Chlorophenyl)methanol (cas: 873-76-7) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R鈥昈鈭?. For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Quality Control of (4-Chlorophenyl)methanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts