Alcohols-buliding-blocks

Effects of Ospemifene on Breast Tissue Morphology and Proliferation: A Comparative Study Versus Other Selective Estrogen Receptor Modulators in Ovariectomized Rats was written by Kangas, L.;Harkonen, P.;Vaananen, K.;Keskitalo, J.;Eigeliene, N.. And the article was included in Hormone and Metabolic Research in 2014.Application of 128607-22-7 This article mentions the following:

Ospemifene is a tissue-selective estrogen agonist/antagonist that was recently approved for the treatment of dyspareunia associated with vulvar and vaginal atrophy, which occurs in up to approx. 50% of postmenopausal women. The current analyses were conducted to determine whether ospemifene exhibits estrogenic activity in the mammary glands of ovariectomized rats and to compare potential estrogenic activity with selective estrogen receptor modulators (tamoxifen, raloxifene, and toremifene). Three sep. studies with differing durations (6, 9, and 28 days) were conducted using similar procedures in ovariectomized Sprague-Dawley rats. Estradiol treatment and sham-treated ovariectomized rats were used as pos. and neg. controls, resp. Cell proliferation was examined using labeled 5-bromo-2-deoxyuridine; cytoplasmic prolactin was characterized with antibody staining. The morphol. of the mammary gland was studied by histol. staining of sections from the right fourth mammary glands, and the excised gland from the left side was used for counting the lobulus number Neither ospemifene nor selective estrogen receptor modulators substantially induced 5-bromo-2-deoxyuridine staining, altered the morphol. of the mammary glands, or changed prolactin immunostaining in ovariectomized rats compared with the ovariectomized controls. With the exception of toremifene, the selective estrogen receptor modulators did not cause a substantial induction in mammary gland lobuli. Estradiol had effects opposite to those of the selective estrogen receptor modulators in these studies. Ospemifene exhibited no substantial estrogenic activity in the mammary gland of ovariectomized rats. Activity in the mammary gland of ovariectomized rats with ospemifene was comparable to raloxifene and tamoxifen. In the experiment, the researchers used many compounds, for example, (Z)-2-(4-(4-Chloro-1,2-diphenylbut-1-en-1-yl)phenoxy)ethan-1-ol (cas: 128607-22-7Application of 128607-22-7).

(Z)-2-(4-(4-Chloro-1,2-diphenylbut-1-en-1-yl)phenoxy)ethan-1-ol (cas: 128607-22-7) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Application of 128607-22-7

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Asymmetric Reductive Dicarbofunctionalization of Alkenes via Nickel Catalysis was written by Anthony, David;Diao, Tianning. And the article was included in Synlett in 2020.Safety of 2-(4-Bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane This article mentions the following:

A summary of the efforts to control enantioselectivity for alkene RCH=CH₂ [R = Ph, 4-(acetyloxy)benzen-1-yl, 1-[(4-methylbenzene)sulfonyl]-1H-indol-5-yl, etc.] and 1H-indene diarylation with a nickel catalyst was presented. This reaction is useful for preparing triarylethanes (1S/1R)-RCH(R¹)CH₂R¹ (R¹ = Ph, 4-chlorophenyl, 2H-1,3-benzodioxol-5-yl, etc.) and (1R,2R/1S,2S)-I. The selectivity is enhanced by an N-oxyl radical additive. In the experiment, the researchers used many compounds, for example, 2-(4-Bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 68716-49-4Safety of 2-(4-Bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane).

2-(4-Bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 68716-49-4) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Safety of 2-(4-Bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Bis(μ-oxo)-Dititanium(IV)-Chiral Binaphthyldisulfonate Complexes for Highly Enantioselective Intramolecular Hydroalkoxylation of Nonactivated Alkenes was written by Xie, Wen-Bin;Li, Zhi. And the article was included in ACS Catalysis in 2021.Application In Synthesis of Sodium 2-methyl-2-propanethiolate This article mentions the following:

A series of chiral 1,1′-binaphthyl-2,2′-disulfonic acids was designed, synthesized, and applied in a highly enantioselective Ti-catalyzed intramol. hydroalkoxylation of nonactivated alkenes. The catalyst is probably a complex between two chiral binaphthyldisulfonate ligands and a bis(μ-oxo)-dititanium(IV) core structure. The sulfonamide groups of the ligands and water are necessary for the catalysis, as they may stabilize the catalytically active complex through hydrogen bonding. Various 2-methylcoumarans were obtained in up to greater than 99% yields and up to 97% enantiomeric excess under mild conditions. In the experiment, the researchers used many compounds, for example, Sodium 2-methyl-2-propanethiolate (cas: 29364-29-2Application In Synthesis of Sodium 2-methyl-2-propanethiolate).

Sodium 2-methyl-2-propanethiolate (cas: 29364-29-2) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Application In Synthesis of Sodium 2-methyl-2-propanethiolate

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Sustainable oxidation of olefins and sulfides employing nanopolyoxomolybdate supported by ionic liquid on dendritic fibrous nanosilica was written by Xiao, BoAn;Sadeghzadeh, Seyed Mohsen. And the article was included in Journal of Molecular Liquids in 2022.Recommanded Product: 3391-86-4 This article mentions the following:

Here, we reported a green and economical method for the oxidation of sulfides to sulfones and sulfoxides in water, and epoxidation of olefins in ethanol with O₂ in the presence of keplerate nanosized polyoxomolybdate [Mo₃₆₈] supported by ionic liquid between DFNS. In order to prepare the catalyst as a substrate to support [Mo₃₆₈] NPs, an ionic liquid was employed to activate the DFNS exterior level. Ionic liquid removed the requirement for a reducing agent and performed as a natural reducing and stabilizing agent for [Mo₃₆₈] NPs. The reaction efficiencies and selectivity were influenced by catalyst concentration A different structural series of olefins and sulfides was set into intended oxidation products in spite of the electronic essence of the substituents. Despite the presence of heterogeneous reaction blends, no problems were noted with reaction progress. Products were easily removed from the green medium, and the catalyst was employed various times without remarkable reduction in performance and selectivity. The results of UV-vis, Raman spectral data, TGA, FT-IR, XRD, TEM, and FESEM showed the involvement of a Mo(VI) peroxo complex in oxidation reactions. In the experiment, the researchers used many compounds, for example, Oct-1-en-3-ol (cas: 3391-86-4Recommanded Product: 3391-86-4).

Oct-1-en-3-ol (cas: 3391-86-4) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Recommanded Product: 3391-86-4

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Molecular properties of bare and microhydrated vitamin B5-calcium complexes was written by Corinti, Davide;Chiavarino, Barbara;Scuderi, Debora;Fraschetti, Caterina;Filippi, Antonello;Fornarini, Simonetta;Crestoni, Maria Elisa. And the article was included in International Journal of Molecular Sciences in 2021.Related Products of 137-08-6 This article mentions the following:

Pantothenic acid, also called vitamin B5, is an essential nutrient involved in several metabolic pathways. It shows a characteristic preference for interacting with Ca(II) ions, which are abundant in the extracellular media and act as secondary mediators in the activation of numerous biol. functions. The bare deprotonated form of pantothenic acid, [panto-H]^–, its complex with Ca(II) ion, [Ca(panto-H)]⁺, and singly charged micro-hydrated calcium pantothenate [Ca(panto-H)(H2O)]⁺ adduct have been obtained in the gas phase by electrospray ionization and assayed by mass spectrometry and IR multiple photon dissociation spectroscopy in the fingerprint spectral range. Quantum chem. calculations at the B3LYP(-D3) and MP2 levels of theory were performed to simulate geometries, thermochem. data, and linear absorption spectra of low-lying isomers, allowing us to assign the exptl. absorptions to particular structural motifs. Pantothenate was found to exist in the gas phase as a single isomeric form showing deprotonation on the carboxylic moiety. On the contrary, free and monohydrated calcium complexes of deprotonated pantothenic acid both present at least two isomers participating in the gas-phase population, sharing the deprotonation of pantothenate on the carboxylic group and either a fourfold or fivefold coordination with calcium, thus justifying the strong affinity of pantothenate for the metal. In the experiment, the researchers used many compounds, for example, Calcium (R)-3-(2,4-dihydroxy-3,3-dimethylbutanamido)propanoate (cas: 137-08-6Related Products of 137-08-6).

Calcium (R)-3-(2,4-dihydroxy-3,3-dimethylbutanamido)propanoate (cas: 137-08-6) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Related Products of 137-08-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Using facile one-pot thiol-ene reaction to prepare elastomers filled with silica was written by Kuang, Haifeng;Yin, Qiyan;Zhang, Ruyi;Wang, Penghan;Gou, Kai;Chen, Huan;Dai, Chenghao;Weng, Gengsheng. And the article was included in Journal of Polymer Research in 2020.Safety of ((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(2-methylacrylate) This article mentions the following:

Novel elastomers filled with different contents of silica through a two-step one-pot thiol-ene reaction were reported. Two monomers of poly (ethylene glycol) dimethacrylate and 1,6-hexanedithiol were used in the first step to synthesize a vinyl-terminated prepolymer at room temperature In the second step, silica and chem. cross-linker trimethylolpropane tris(3-mercaptopropionate) were directly added to the prepolymer in sequence and transparent elastomers were obtained in 30 min at room temperature The crosslinking kinetics and mech. properties in the presence of different contents of silica were investigated in detail by rheol., tensile and cyclic loading measurements. It was found that silica had a significant reinforcing effect on the mech. properties of the elastomers. Our synthetic method is simple, solvent-free and energy- and cost-efficient. Our findings pave a new way to fabricate novel sulfur-containing elastomers using thiol-ene chem. In the experiment, the researchers used many compounds, for example, ((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(2-methylacrylate) (cas: 109-17-1Safety of ((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(2-methylacrylate)).

((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(2-methylacrylate) (cas: 109-17-1) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Safety of ((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(2-methylacrylate)

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Impact of calcium salts addition on stability of milk used in cottage cheese production was written by Ziarno, Malgorzata;Semeniuk, Ewa;Kycia, Katarzyna. And the article was included in Zywnosc in 2004.Reference of 5743-47-5 This article mentions the following:

An effective way to increase Ca levels in cottage cheese is the addition of Ca salts to the pasteurized processed milk prior to its heat treatment (repasteurization). The impact of different Ca salts (Ca L-lactate pentahydrate, Ca lactogluconate dihydrate, Ca gluconate, CaCl₂, Ca citrate tetrahydrate, CaCO₃) added on the heat stability and some physicochem. properties of the processed milk used to manufacture cottage cheese was examined The water-soluble Ca salts (L-lactate, lactogluconate, gluconate, CaCl₂) added to the milk increased its acidity. The Ca-fortified milk had decreased heat stability and milk proteins precipitated during milk repasteurization (74°C for 5 min). The highest quantity of a water-soluble Ca salt added that did not precipitate the proteins during repasteurization was the addition of 0.15% anhydrous CaCl₂; with this addition the Ca content in the processed milk was increased by 55 mg%. An addnl. test for heat stability of milk proteins indicated that it was better to add 35 mg% Ca as CaCl₂ or 20 mg% Ca as the other Ca salts. The addition of water-insoluble Ca salts (citrate, carbonate) allowed to increase the Ca levels in the processed milk without neg. effects of protein precipitation Addition of even 5% of these Ca salts caused no decrease in the protein heat stability and no coagulation during the milk repasteurization. Various Ca salt combinations added to the processed milk provided higher Ca levels compared with single Ca salts added. When 63 mg% Ca as citrate and 20 mg% Ca as lactate were added together, the Ca level rose by 83 mg%. The use of Ca salt mixtures did not precipitate the proteins. In the experiment, the researchers used many compounds, for example, Calcium 2-hydroxypropanoate pentahydrate (cas: 5743-47-5Reference of 5743-47-5).

Calcium 2-hydroxypropanoate pentahydrate (cas: 5743-47-5) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Reference of 5743-47-5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Method development for the simultaneous estimation of ospemifine by using RP-HPLC was written by Chaitanya, Mitta;Swathi, Kalepu;Raju, P. Narayan;Swathi, Koduru. And the article was included in International Journal of Pharma Research and Health Sciences in 2015.Recommanded Product: (Z)-2-(4-(4-Chloro-1,2-diphenylbut-1-en-1-yl)phenoxy)ethan-1-ol This article mentions the following:

A selective and sensitive stability-indicating high-performance liquid chromatog. method was developed and validated for the determination of Ospemifine. 10 mg of Ospemifine was dissolved in mobile phase. The solution was scanned from 200-400 nm the spectrum was obtained. The overlay spectrum was used for selection of wavelength for Ospemifine. The isobestic point was taken as detection wavelength. The separation was good, peak shape was good, so we conclude that there is no required for decrease the retention times of peak, so it is taken as final method. Mix a mixture of 40 mL water (40%) and 60 mL of Acetonitrile (60%) and degassed in ultrasonic water bath for 5 min. Filter through 0.22 μ filter under vacuum filtration.10 mg of Ospemifine working standard was accurately weighed and transferred into a 10 mL clean dry volumetric flask and add about 2 mL of diluent and sonicate to dissolve it completely and make volume up to the mark with the same solvent (Stock solution). Further pipet out 1.0 mL from the above stock solution into a 10 mL volumetric flask and was diluted up to the mark with diluent. The chromatog. method development for the estimation of Ospemifine were optimized by several trials for various parameters as different column, flow rate and mobile phase, finally the following chromatog. method was selected for the separation and quantification of Ospemifine in API and pharmaceutical dosage form by RP-HPLC method. The retention time of Ospemifine was found to be 2.425 mins. The system suitability parameters for Ospemifine such as theor. plates and tailing factor were found to be 4146, 1.2. The % purity Ospemifine in pharmaceutical dosage form was found to be 99.56%. In the experiment, the researchers used many compounds, for example, (Z)-2-(4-(4-Chloro-1,2-diphenylbut-1-en-1-yl)phenoxy)ethan-1-ol (cas: 128607-22-7Recommanded Product: (Z)-2-(4-(4-Chloro-1,2-diphenylbut-1-en-1-yl)phenoxy)ethan-1-ol).

(Z)-2-(4-(4-Chloro-1,2-diphenylbut-1-en-1-yl)phenoxy)ethan-1-ol (cas: 128607-22-7) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Recommanded Product: (Z)-2-(4-(4-Chloro-1,2-diphenylbut-1-en-1-yl)phenoxy)ethan-1-ol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Characterization and Dioxygen Reactivity of a New Series of Coordinatively Unsaturated Thiolate-Ligated Manganese(II) Complexes was written by Coggins, Michael K.;Toledo, Santiago;Shaffer, Erika;Kaminsky, Werner;Shearer, Jason;Kovacs, Julie A.. And the article was included in Inorganic Chemistry in 2012.Formula: C7H9NO This article mentions the following:

The synthesis, structural, and spectroscopic characterization of four new coordinatively unsaturated mononuclear thiolate-ligated manganese(II) complexes [Mn^II(S^Me2N₄(6-Me-DPEN))](BF₄) (1), [Mn^II(S^Me2N₄(6-Me-DPPN))](BPh₄)·MeCN (3), [Mn^II(S^Me2N₄(2-QuinoPN))](PF₆)·MeCN·Et₂O (4), and [Mn^II(S^Me2N₄(6-H-DPEN))(MeOH)](BPh₄) (5) S^Me2N₄(6-Me-DPEN), S^Me2N₄(6-Me-DPPN), S^Me2N₄(2-QuinoPN) and S^Me2N₄(6-H-DPEN) is Schiff base from 3-mercapto-3-methyl-2-butanone and N,N-bis(6-methyl-2-pyridylmethyl)ethane-1,2-diamine, N,N-bis(6-methyl-2-pyridylmethyl)propane-1,3-diamine, N,N-bis(2-quinolinemethyl)-propane-1,3-diamine, N,N-(bis(2-pyridylmethyl)ethane-1,2-diamine, resp.) are described, along with their magnetic, redox, and reactivity properties. These complexes are structurally related to recently reported [Mn^II(S^Me2N₄(2-QuinoEN))](PF₆) (2) (Coggins, M. K.; Kovacs, J. A. J. Am. Chem. Soc.2011, 133, 12470). Dioxygen addition to complexes 1–5 gave five new rare examples of Mn(III) dimers containing a single, unsupported oxo bridge: [Mn^III(S^Me2N₄(6-Me-DPEN))]₂(μ-O)(BF₄)₂·2MeOH (6), [Mn^III(S^Me2N₄(QuinoEN))]₂(μ-O)(PF₆)₂·Et₂O (7), [Mn^III(S^Me2N₄(6-Me-DPPN))]₂(μ-O)(BPh₄)₂ (8), [Mn^III(S^Me2N₄(QuinoPN))]₂(μ-O)(BPh₄)₂ (9), and [Mn^III(S^Me2N₄(6-H-DPEN))]₂(μ-O)(PF₆)₂·2MeCN (10). Labeling studies show that the oxo atom is derived from ¹⁸O₂. Ligand modifications, involving either the insertion of a methylene into the backbone or the placement of an ortho substituent on the N-heterocyclic amine, noticeably modulate the magnetic and reactivity properties. Fits to solid-state magnetic susceptibility data show that the Mn(III) ions of μ-oxo dimers 6–10 are moderately antiferromagnetically coupled, with coupling constants (2J) that fall within the expected range. Metastable intermediates, which ultimately convert to μ-oxo bridged 6 and 7, are observed in low-temperature reactions between 1 and 2 and dioxygen. Complexes 3–5, however, do not form observable intermediates, thus illustrating the effect that relatively minor ligand modifications have upon the stability of metastable dioxygen-derived species. In the experiment, the researchers used many compounds, for example, 6-Methyl-2-pyridinemethanol (cas: 1122-71-0Formula: C7H9NO).

6-Methyl-2-pyridinemethanol (cas: 1122-71-0) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Formula: C7H9NO

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Inhibition of Sphingosine-1-Phosphate Lyase for the Treatment of Autoimmune Disorders was written by Bagdanoff, Jeffrey T.;Donoviel, Michael S.;Nouraldeen, Amr;Tarver, James;Fu, Qinghong;Carlsen, Marianne;Jessop, Theodore C.;Zhang, Haiming;Hazelwood, Jill;Nguyen, Huy;Baugh, Simon D. P.;Gardyan, Michael;Terranova, Kristen M.;Barbosa, Joseph;Yan, Jack;Bednarz, Mark;Layek, Suman;Taylor, Jerry;Digeorge-Foushee, Ann Marie;Gopinathan, Suma;Bruce, Debra;Smith, Traci;Moran, Liam;O’Neill, Emily;Kramer, Jeff;Lai, Zhong;Kimball, S. David;Liu, Qingyun;Sun, Weimei;Yu, Sean;Swaffield, Jonathan;Wilson, Alan;Main, Alan;Carson, Kenneth G.;Oravecz, Tamas;Augeri, David J.. And the article was included in Journal of Medicinal Chemistry in 2009.Formula: C9H10BrNO2 This article mentions the following:

During nearly a decade of research dedicated to the study of sphingosine signaling pathways, we identified sphingosine-1-phosphate lyase (S1PL) as a drug target for the treatment of autoimmune disorders. S1PL catalyzes the irreversible decomposition of sphingosine-1-phosphate (S1P) by a retro-aldol fragmentation that yields hexadecanaldehyde and phosphoethanolamine. Genetic models demonstrated that mice expressing reduced S1PL activity had decreased numbers of circulating lymphocytes due to altered lymphocyte trafficking, which prevented disease development in multiple models of autoimmune disease. Mechanistic studies of lymphoid tissue following oral administration of 2-acetyl-4(5)-(1(R),2(S),3(R),4-tetrahydroxybutyl)-imidazole (THI) showed a clear relationship between reduced lyase activity, elevated S1P levels, and lower levels of circulating lymphocytes. Our internal medicinal chem. efforts discovered potent analogs of 3 bearing heterocycles as chem. equivalent of the pendant carbonyl present in the parent structure. Reduction of S1PL activity by oral administration of these analogs recapitulated the phenotype of mice with genetically reduced S1PL expression. In the experiment, the researchers used many compounds, for example, 2-Bromo-6-(2-methyl-1,3-dioxolan-2-yl)pyridine (cas: 49669-14-9Formula: C9H10BrNO2).

2-Bromo-6-(2-methyl-1,3-dioxolan-2-yl)pyridine (cas: 49669-14-9) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Formula: C9H10BrNO2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts