Category: alcohols-buliding-blocks

Travassos, Ana Rita published the artcileNon-fragrance allergens in specific cosmetic products, Category: alcohols-buliding-blocks, the publication is Contact Dermatitis (2011), 65(5), 276-285, database is CAplus and MEDLINE.

Objectives. Reports about the nature of the ingredients responsible for allergic contact dermatitis caused by specific cosmetic products are scarce. Methods. Between Jan. 2000 and Dec. 2010, the specific cosmetic products having caused allergic contact dermatitis, as well as the individual allergenic cosmetic ingredients present in them, were recorded by use of a standardized form. Results. Among 11 different categories of cosmetic product, skin care products, followed by hair care and body-cleansing products, were most often involved. The presence of the allergenic ingredient(s) in a specific cosmetic product was confirmed according to the ingredient label in 959 of 1448 records. Six hundred and twenty-one of 959 concerned non-fragrance components, preservatives being responsible for 58% of them. Reactions to formaldehyde and formaldehyde-releasers were most often correlated with body-cleansing products, particularly 2-bromo-2-nitropropane-1,3-diol and skin care products. They were followed by the methylchloroisothiazolinone/methylisothiazolinone mixture, most frequently found as allergens in hair care and intimate hygiene products, and facial cleansers (in the last category together with diazolidinyl urea). Octocrylene was by far the most frequent (photo)allergen in sun care products. Conclusions. This study provides information on the presence and frequency of allergens in specific causal cosmetic products.

Contact Dermatitis published new progress about 70445-33-9. 70445-33-9 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is 3-((2-Ethylhexyl)oxy)propane-1,2-diol, and the molecular formula is C20H28B2O4S2, Category: alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Robichaud, David J. published the artcileDetermining the effects of concerted elimination reactions in the pyrolysis of lignin using model compounds, Related Products of alcohols-buliding-blocks, the publication is Preprints of Symposia – American Chemical Society, Division of Fuel Chemistry (2012), 57(1), 174, database is CAplus.

Lignin pyrolysis occurs over a very broad temperature range at much higher temperatures compared with pyrolysis of the other two primary components of biomass (cellulose and hemicellulose). Due to the higher temperatures required to deconstruct the lignin polymer it promotes the formation of radicals that can lead to excessive char formation due to cross linking and forms more reactive products. It is therefore advantageous to discover new catalytic pathways that can disassemble lignin at lower temperatures, forming more stable products improving the yields of hydrocarbons, and generating less particulate material. This study investigated the thermochem. of the lignin linkage units using ab initio calculations on dimeric model compounds Quantum mech. electronic structure calculations were used to compare the energies of the competing decomposition pathways for the dimer compounds and to estimate the rates of the reactions. The theor. calculations indicated that concerted elimination pathways dominate over bond homolysis reactions under typical pyrolysis conditions. However, this does not mean that concerted elimination will be the dominant loss process for lignin. Bimol. radical chem. could very well dwarf the unimol. pathways investigated in this study. These concerted pathways tend to form stable, reasonably non-reactive products that would be more suited producing a fungible bio-oil for the production of liquid transportation fuels.

Preprints of Symposia – American Chemical Society, Division of Fuel Chemistry published new progress about 70110-65-5. 70110-65-5 belongs to alcohols-buliding-blocks, auxiliary class Benzene,Alcohol,Ether,Benzene Compounds, name is 2-Phenoxy-1-phenylpropane-1,3-diol, and the molecular formula is C15H16O3, Related Products of alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Robichaud, David J. published the artcileDetermining the effects of concerted elimination reactions in the pyrolysis of lignin using model compounds, COA of Formula: C15H16O3, the publication is Preprints of Symposia – American Chemical Society, Division of Fuel Chemistry (2012), 57(1), 1038, database is CAplus.

Lignin pyrolysis is a significant impediment in forming liquid fuel from biomass. Lignin pyrolyzes at a higher temperature than other biomass components (ie cellulose and hemicellulose) and tends to form radicals which lead to crosslinking and ultimately char formation. A primary step in advancing biomass-to-fuel technol. will be to discover mechanisms that can disassemble lignin at lower temperatures and depolymerize lignin into more stable products. We have studied the thermochem. of the various inter-linkage units found in lignin (β-O4, α-O4, β-β, β-O5, etc.) using electronic structure calculations at the M06-2x/6-311++G(d,p) on a series of dimer model compounds In addition to the usually-assumed bond homolysis reactions, we have studied a variety of concerted elimination pathways that will tend to produce closed-shell stable products. Such a bottom-up approach could aid in the targeted development of catalysts that produce more desirable products under less severe reactor conditions.

Preprints of Symposia – American Chemical Society, Division of Fuel Chemistry published new progress about 70110-65-5. 70110-65-5 belongs to alcohols-buliding-blocks, auxiliary class Benzene,Alcohol,Ether,Benzene Compounds, name is 2-Phenoxy-1-phenylpropane-1,3-diol, and the molecular formula is C15H16O3, COA of Formula: C15H16O3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Zhao, Jian published the artcileDiscovery of substituted 3H-pyrido[2,3-d]pyrimidin-4-ones as potent, biased, and orally bioavailable sst2 agonist, Application In Synthesis of 1256345-79-5, the publication is Bioorganic & Medicinal Chemistry Letters (2020), 30(21), 127496, database is CAplus and MEDLINE.

The discovery of a novel 3H-pyrido[2,3-d]pyrimidin-4-one series as potent and biased sst2 agonists is described. This class of mols. exhibits excellent sst2 potency and selectivity against sst1, sst3, and sst5 receptors, and they are significantly more potent at inhibiting cAMP production than inducing internalization. The orally bioavailable 6-(3-chloro-5-methylphenyl)-3-(3-fluoro-5-hydroxyphenyl)-5-({methyl[(2S)-pyrrolidin-2-ylmethyl]amino}methyl)-3H,4H-pyrido[2,3-d]pyrimidin-4-one (36) also suppresses GH secretion in GHRH-challenged rats in a dose-dependent manner.

Bioorganic & Medicinal Chemistry Letters published new progress about 1256345-79-5. 1256345-79-5 belongs to alcohols-buliding-blocks, auxiliary class Boronic acid and ester,Benzene,Phenol,Boronic Acids,Boronic Acids,Boronic acid and ester, name is (3-Hydroxy-5-methylphenyl)boronic acid, and the molecular formula is C10H9NO4S, Application In Synthesis of 1256345-79-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Li, Wen-Pei published the artcileAcid-Free Copper-Catalyzed Electrophilic Nitration of Electron-Rich Arenes with Guanidine Nitrate, Safety of 4-Propylphenol, the publication is Journal of Organic Chemistry, database is CAplus and MEDLINE.

A practical copper-catalyzed nitration of electron-rich arenes with trimethylsilyl chloride and guanidine nitrate is reported. A variety of nitrated products were generated in moderate to excellent yields (32%-99%) at ambient temperature under acid free, open-flask and operationally simple conditions.

Journal of Organic Chemistry published new progress about 645-56-7. 645-56-7 belongs to alcohols-buliding-blocks, auxiliary class Liquid Crystal &OLED Materials, name is 4-Propylphenol, and the molecular formula is C9H12O, Safety of 4-Propylphenol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Li, Zhan-Ku published the artcilePretreatment of sweet sorghum stalk with aqueous hydrogen peroxide for enhancing methanolysis and property of the bio-oil, Name: 4-Propylphenol, the publication is Renewable Energy (2021), 1127-1136, database is CAplus.

Alcoholysis is a promising approach for converting biomass into fuels and/or chems. under mild conditions. However, the effect of pretreatment on biomass alcoholysis was rarely reported. Herein, the effect of pretreatment with H₂O₂ on sweet sorghum stalk (SSS) methanolysis was examined The results show that the pretreatment could markedly improve the bio-oil (BO) yield and decrease the appropriate temperature for obtaining maximum BO yield. The appropriate temperature for pretreated SSS methanolysis was determined to be 280 °C and the maximum BO yield is 44 wt%. In addition, higher heating values of the BOs were also enhanced based on elemental anal. According to anal. with gas chromatograph/mass spectrometer, phenolic compounds, esters, and sugars are predominant in the BOs, and the yield of phenolic compounds significantly increased from 91.75 to 111.68 mg·g^-1 by the pretreatment. Moreover, polar species in the BOs decreased and deoxygenation occurred during pretreated SSS methanolysis. Analyses with scanning electron microscope and N₂ physisorption reveal that pretreated SSS has more grooves and higher sp. surface area and anomalous porosity than SSS. According to analyses with Fourier transform IR spectrometer and X-ray photoelectron spectrometer, oxygen functional groups mainly in the forms of C=O and COO were introduced into SSS by the pretreatment. The changes of phys. and chem. structures should be responsible for enhancing SSS methanolysis and property of the BO.

Renewable Energy published new progress about 645-56-7. 645-56-7 belongs to alcohols-buliding-blocks, auxiliary class Liquid Crystal &OLED Materials, name is 4-Propylphenol, and the molecular formula is C9H12O, Name: 4-Propylphenol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Feng, Yan published the artcileGas chromatography-mass spectrometry analysis of floral fragrance-related compounds in scented rose (Rosa hybrida) varieties and a subsequent evaluation on the basis of the analytical hierarchy process, Recommanded Product: cis-3,7-Dimethyl-2,6-Octadien-1-Ol, the publication is Plant Physiology and Biochemistry (Issy-les-Moulineaux, France) (2022), 368-377, database is CAplus and MEDLINE.

Scented rose (Rosa hybrida) varieties are valued as ornamentals, but they also contain volatile organic compounds (VOCs) that produce pleasant aromas. In plants, aromas are produced via metabolism during growth, and each aroma compound has a unique function. In this study, the floral aroma compounds of diverse scented rose varieties were analyzed and classified. The VOCs of different rose varieties were qual. and quant. analyzed via headspace solid-phase microextraction combined with gas chromatog. and mass spectrometry. The test materials were the mature flowers of 55 scented rose varieties that were cultivated under identical conditions. Seventeen important aroma compounds were selected and an anal. hierarchy process (AHP)-based method was developed to identify the most suitable essential oil resources, aromatherapy resources, and healthcare resources. A floral fragrance evaluation model was established for the comprehensive evaluation of the scented rose varieties. The 55 varieties were classified into three grades according to their suitability for each use. ′Soeur Emmanuelle′, ′Wollerton Old Hall′, ′Accademia′, and ′Tianmidemeng′ were revealed to be suitable essential oil, aromatherapy, and healthcare resources. On the basis of their aroma compound types, the fifty-five rose varieties were divided into eight groups. The results of this study provide the theor. basis for the classification of rose flower aromas as well as the rational use of diverse rose varieties to further develop the rose industry. nerol, geraniol, citronellol, phenethyl alc., trans-3-hexenyl acetate, 1,3,5-Trimethoxybenzene , phenylethanol acetate, vanillin ace-tate,citronellyl acetate, neryl acetate, hexyl acetate, 3,5-Dimethoxyben-zoic, α-elemene, β-elemene, γ-elemene and myrcene

Plant Physiology and Biochemistry (Issy-les-Moulineaux, France) published new progress about 106-25-2. 106-25-2 belongs to alcohols-buliding-blocks, auxiliary class Natural product, name is cis-3,7-Dimethyl-2,6-Octadien-1-Ol, and the molecular formula is C10H18O, Recommanded Product: cis-3,7-Dimethyl-2,6-Octadien-1-Ol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Wang, Pengxin published the artcileDearomatization-rearomatization strategy of tyrosine for peptide/protein modification through thiol-addition reactions, Computed Properties of 4410-99-5, the publication is Chemical Communications (Cambridge, United Kingdom) (2021), 57(96), 12968-12971, database is CAplus and MEDLINE.

We have developed a dearomatization-rearomatization strategy for the modification of peptides/proteins through a thiol-Michael addition to the electrophilic cyclohexadienone intermediate that is generated in situ via the oxidation of tyrosine. This strategy enriches the conjugation toolbox and has great potential for applications in medicinal chem. and chem. biol.

Chemical Communications (Cambridge, United Kingdom) published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C9H8O4, Computed Properties of 4410-99-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Jia, Kangle published the artcileThermal, light and pH triple stimulated changes in self-assembly of a novel small molecular weight amphiphile binary system, Application of 2-Hydroxy-4-(trifluoromethyl)benzoic acid, the publication is RSC Advances (2015), 5(1), 640-642, database is CAplus.

Novel multiple stimuli-responsive fluids based on an azobenzene-contained surfactant 1-[2-(4-decylphenylazo-phenoxy)-ethyl]-3-methylimidazolium bromide (C10AZOC2IMB) and a hydrotrope 4-(trifluoromethyl) salicylic acid (4FS) can be reversibly induced by temperature, light and pH from vesicles to wormlike micelles. UV-vis spectra, rheol. and cryo-TEM measurements were utilized to prove the self-assembly transitions.

RSC Advances published new progress about 328-90-5. 328-90-5 belongs to alcohols-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Carboxylic acid,Benzene,Phenol, name is 2-Hydroxy-4-(trifluoromethyl)benzoic acid, and the molecular formula is C8H5F3O3, Application of 2-Hydroxy-4-(trifluoromethyl)benzoic acid.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Chen, Xu published the artcileIron-Catalyzed, Markovnikov-Selective Hydroboration of Styrenes, Quality Control of 608534-44-7, the publication is Organic Letters (2017), 19(5), 969-971, database is CAplus and MEDLINE.

A highly Markovnikov-selective, iron-catalyzed hydroboration of styrenes is reported using available oxazolinylphenyl picolinamide as the ligand to afford the branched hydroboration products with up to >50/1 b/l. This reaction is operationally simple and could be carried out in gram scale.

Organic Letters published new progress about 608534-44-7. 608534-44-7 belongs to alcohols-buliding-blocks, auxiliary class Other Aromatic,Boronic acid and ester,Boronate Esters,Boronic Acids,Boronic acid and ester, name is 2-(2,3-Dihydro-1H-inden-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, and the molecular formula is C15H21BO2, Quality Control of 608534-44-7.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts