Category: alcohols-buliding-blocks

Bag, Raghunath published the artcileK2S2O8-Mediated Dioxygenation of Aryl Alkenes Using N-Hydroxylamines and Air, SDS of cas: 92093-23-7, the main research area is diol preparation; aryl alkene hydroxylamine dioxygenation potassium persulfate air.

The vicinal dioxygenation of aryl alkenes is reported using N-hydroxylamines and air in the presence of potassium persulfate (K2S2O8). The alkene is first oxidized to β-aminoxy alkyl hydroperoxide, which is in situ reduced to the diol e.g., I using molybdenum hexacarbonyl [Mo(CO)6] and base. Metal-free, aerobic conditions and the substrate scope are the important practical features.

ChemistrySelect published new progress about Aryl alkenes Role: RCT (Reactant), RACT (Reactant or Reagent). 92093-23-7 belongs to class alcohols-buliding-blocks, name is 1-(4-Bromophenyl)ethane-1,2-diol, and the molecular formula is C8H9BrO2, SDS of cas: 92093-23-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Gao, Xiaofang published the artcileIodine-Initiated Dioxygenation of Aryl Alkenes Using tert-Butylhydroperoxides and Water: A Route to Vicinal Diols and Bisperoxides, Application of 1-(4-Bromophenyl)ethane-1,2-diol, the main research area is vicinal diol green preparation; aryl alkene dioxygenation iodine catalyst; bisperoxide green preparation; alkene aryl dioxygenation iodine catalyst.

An environment-friendly and efficient dioxygenation of aryl alkenes for the construction of vicinal diols ArCH(OH)CH(OH)R [Ar = Ph, 2-MeC6H4, 4-MeC6H4, etc.; R = H, Br, Me, etc.] was developed in water with iodine as the catalyst and tert-butylhydroperoxides (TBHPs) as the oxidant. The protocol was efficient, sustainable, and operationally simple. Detailed mechanistic studies indicated that one of the hydroxyl groups was derived from water and the other one was derived from TBHP. Addnl., the bisperoxides ArCH(OOtBu)CH(OOtBu)R [Ar = Ph, 4-MeC6H4, 3-FC6H4, etc.] could be obtained in good yields with iodine as the catalyst, Na2CO3 as the additive, and propylene carbonate as the solvent, instead.

Journal of Organic Chemistry published new progress about Aryl alkenes Role: RCT (Reactant), RACT (Reactant or Reagent). 92093-23-7 belongs to class alcohols-buliding-blocks, name is 1-(4-Bromophenyl)ethane-1,2-diol, and the molecular formula is C8H9BrO2, Application of 1-(4-Bromophenyl)ethane-1,2-diol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yin, Fucheng published the artcileAryl Halides as Halogenation Reagents in the Bromination and Iodination of Arene-Tethered Diols, Recommanded Product: 1-(4-Bromophenyl)ethane-1,2-diol, the main research area is dioxolanyl halide preparation green chem; arene tether diol aryl halide halogenation palladium catalyst.

The demonstrate usage of aryl bromides (Me 2-bromobenzoate) and aryl iodides (such as 1-iodo-2-nitrobenzene, Me 2-iodobenzoate, 2-iodo-benzenesulfinic acid, etc.) in C-Br or C-I bond formation were described. Me 2-bromobenzoate and 2-nitrophenyl iodides were developed as mild and effective bromination and iodination reagents for functionalization of arene-tethered diols I (R = Ph, naphthalen-2-yl, 3,4-dichlorophenyl, etc.). This efficient cascaded catalysis can be applied to the total syntheses of natural product Mafaicheenamine A and Claulamine A.

Organic Letters published new progress about Aryl iodides Role: RCT (Reactant), RACT (Reactant or Reagent). 92093-23-7 belongs to class alcohols-buliding-blocks, name is 1-(4-Bromophenyl)ethane-1,2-diol, and the molecular formula is C8H9BrO2, Recommanded Product: 1-(4-Bromophenyl)ethane-1,2-diol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Giboulot, Steven published the artcileFlat and Efficient HCNN and CNN Pincer Ruthenium Catalysts for Carbonyl Compound Reduction, Quality Control of 124-76-5, the main research area is arylpyridinylmethanamine benzoquinoline aminomethylpyridine HCNN CNN pincer ruthenium catalyst preparation; carbonyl compound reduction HCNN CNN pincer ruthenium catalyzed; aminomethylbenzoquinoline ruthenium phosphine carbonyl preparation crystal mol structure catalyst; aryl methyl ketone transfer hydrogenation catalyst preparation.

The bidentate HCNN dicarbonyl ruthenium complexes trans,cis-[RuCl2(HCNN)(CO)2] (1-3) and trans,cis-[RuCl2(ampy)(CO)2] (1a) were prepared by reaction of [RuCl2(CO)2]n with 1-[6-(4′-methylphenyl)pyridin-2-yl]methanamine, benzo[h]quinoline (HCNN), and 2-(aminomethyl)pyridine (ampy) ligands. Alternatively, the derivatives 1-3 were obtained from the reaction of RuCl3 hydrate with HCO2H and HCNN. The pincer CNN cis-[RuCl(CNN)(CO)2] (4) was isolated from 1 by reaction with NEt3. The monocarbonyl complexes trans-[RuCl2(HCNN)(PPh3)(CO)] (5-7) were synthesized from [RuCl2(dmf)(PPh3)2(CO)] and HCNN ligands, while the diacetate trans-[Ru(OAc)2(HCNN)(PPh3)(CO)] (8) was obtained from [Ru(OAc)2(PPh3)2(CO)]. Carbonylation of cis-[RuCl(CNN)(PPh3)2] with CO afforded the pincer derivatives [RuCl(CNN)(PPh3)(CO)] (9-11). Treatment of 9 with Na[BArf]4 and PPh3 gave the cationic complex trans-[Ru(CNN)(PPh3)2(CO)][BArf4] (12). The dicarbonyl derivatives 1-4, in the presence of PPh3 or PCy3, and the monocarbonyl complexes 5-12 catalyzed the transfer hydrogenation (TH) of acetophenone (a) in 2-propanol at reflux (S/C = 1000-100000 and TOF up to 100000 h-1). Compounds 1-3, with PCy3, and 6 and 8-10 were proven to catalyze the TH of carbonyl compounds, including α,β-unsaturated aldehydes and bulky ketones (S/C and TOF up to 10000 and 100000 h-1, resp.). The derivatives 1-3 with PCy3 and 5 and 6 catalyzed the hydrogenation (HY) of a (H2, 30 bar) at 70° (S/C = 2000-10000). Complex 5 was active in the HY of diaryl ketones and aryl Me ketones, leading to complete conversion at S/C = 10000.

Organometallics published new progress about Aryl ketones Role: RCT (Reactant), RACT (Reactant or Reagent). 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Quality Control of 124-76-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Karakas, Duygu Elma published the artcileKetone transfer hydrogenation reactions catalyzed by catalysts based on a phosphinite ligand, COA of Formula: C5H12O, the main research area is furanylethyldiphenylphosphinite preparation ruthenium iridium complexation; ketone transfer hydrogenation catalyzed furanylethyldiphenylphosphinite ruthenium iridium complex.

Reaction of (±)-1-(2-furyl)ethanol with an equivalent Ph2PCl in the presence of Et3N proceeds in dry toluene under an argon atm. to give 1-(furan-2-yl)ethyldiphenylphosphinite (1) in good yield. Mononuclear complexes [dichloro(η6-p-cymene)(1-furan-2-ylethyldiphenylphosphinite)ruthenium(II)] (2), [dichloro(η6-benzene)(1-furan-2-ylethyldiphenylphosphinite)ruthenium(II)] (3), [chloro(η4-1,5-cyclooctadiene)(1-furan-2-ylethyldiphenylphosphinite)rhodium(I)] (4) and [dichloro(η5-pentamethylcyclopentadienyl)(1-furan-2-ylethyldiphenylphosphinite)iridium(III)] (5) were synthesized and characterized by microanal., IR, MS, and NMR spectroscopies. The complexes are employed as catalysts in transfer hydrogenation of aromatic ketones. The complexes catalyzed reduction of a variety of aromatic ketone substrates bearing electron-withdrawing or donating substituents with very high conversion rates (up to 99%); 5 was the most efficient catalyst for the transfer hydrogenation of ketones.

Journal of Coordination Chemistry published new progress about Aryl ketones Role: RCT (Reactant), RACT (Reactant or Reagent). 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, COA of Formula: C5H12O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Moradi, Sasan published the artcileAchieving high thermal conductivity in epoxy composites: effect of boron nitride particle size and matrix-filler interface, Quality Control of 7575-23-7, the main research area is boron nitride epoxy composite thermal conductivity particle size interface; boron nitride; differential scanning calorimetry (DSC); epoxy; thermal conductivity; thiol.

For the thermal management of high watt d. circuit layers, it is common to use a filled epoxy system to provide an elec. insulating but thermally conducting bond to a metal substrate. An epoxy-thiol system filled with boron nitride (BN), in the form of 2, 30 and 180μm platelets, has been investigated with a view to achieving enhanced thermal conductivity The effect of BN content on the cure reaction kinetics has been studied by differential scanning calorimetry and the thermal conductivity of the cured samples has been measured by the transient hot bridge method. The heat of reaction and the glass transition temperature of the fully cured samples are both independent of the BN content, but the cure reaction kinetics is systematically affected by both BN content and particle size. These results can be correlated with the thermal conductivity of the cured systems, which is found to increase with both BN content and particle size. For a given BN content, the thermal conductivity found here is significantly higher than most others reported in the literature; this effect is attributed to a Lewis acid-base interaction between filler and matrix.

Polymers (Basel, Switzerland) published new progress about Epoxy resins Role: RCT (Reactant), RACT (Reactant or Reagent). 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, Quality Control of 7575-23-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Derasp, Joshua S. published the artcileRhodium-Catalyzed Synthesis of Amides from Functionalized Blocked Isocyanates, Quality Control of 22483-09-6, the main research area is rhodium catalyst coupling boroxine blocked masked isocyanate; synthesis amide.

Isocyanates are useful building blocks for the synthesis of amides, although their widespread use has been limited by their high reactivity, which often results in poor functional group tolerance and a propensity to oligomerize. Herein, a rhodium-catalyzed synthesis of amides is described coupling boroxines with blocked (masked) isocyanates. The success of the reaction hinges on the ability to form both the isocyanate and the organorhodium intermediates in situ. Relying on masked isocyanate precursors and on the high reactivity of the organorhodium intermediate results in broad functional group tolerance, including protic nucleophilic groups such as amines, anilines, and alcs.

ACS Catalysis published new progress about Amides Role: SPN (Synthetic Preparation), PREP (Preparation). 22483-09-6 belongs to class alcohols-buliding-blocks, name is 2,2-Dimethoxyethanamine, and the molecular formula is C4H11NO2, Quality Control of 22483-09-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yan, Linjie published the artcileDesign, synthesis and evaluation of 2′-acetylene-7-deaza-adenosine phosphoamidate derivatives as anti-EV71 and anti-EV-D68 agents, Recommanded Product: 3-Pentanol, the main research area is alkylaminopyrrolopyrimidinylethynyl tetrahydrofuranylmethoxyphenoxyphosphorylaminopropanoate preparation diastereoselective antiviral SAR pharmacokinetic; Antiviral; Enterovirus; NITD008; Nucleoside/nucleotide inhibitor.

A series of phosphoamidate derivatives I [R1 = Me, iso-Bu, cyclohexyl etc.; R2 = H, Me, benzyl etc.] (NITD008) were synthesized and evaluated for their in-vitro antiviral activities against the enteroviruses EV71 and EV-D68. The phosphoamidate containing I [R1 = n-hexyl; R2 = Me] a hexyl ester of L-alanine exhibited the most promising activity against EV71 (IC50 = 0.13 ± 0.08 μM) and were 4-times more potent than NITD008. Meanwhile, the derivative containing a cyclohexyl ester of L-alanine I [R1 = cyclohexyl; R2 = Me] exhibited the most potent activity with high selectivity index against both EV71 (IC50 = 0.19 ± 0.27 μM, SI = 117.00) and EV-D68 (IC50 = 0.17 ± 0.16 μM, SI = 130.76), which were both higher than that of NITD008. The results indicated that the phosphoamidate I [R1 = cyclohexyl; R2 = Me] were the most promising candidate for further development as antiviral agents for the treatment of both EV71 and EV-D68 infection.

European Journal of Medicinal Chemistry published new progress about Amino acids Role: RCT (Reactant), RACT (Reactant or Reagent). 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, Recommanded Product: 3-Pentanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Gong, Lingzhen published the artcileSelective construction of fused heterocycles by an iridium-catalyzed reductive three-component annulation reaction, Product Details of C10H18O, the main research area is chromenoquinolinone preparation diastereoselective; cyclohexanedione quinolinium bromide selective reductive annulation iridium catalyzed; chromenopyranoquinolinone preparation diastereoselective; hydroxycoumarin quinolinium bromide selective reductive annulation iridium catalyzed.

Here, through an initial pretreatment of N-heteroarenes with alkyl bromide, a syn-selective construction of functional fused heterocycles, chromenoquinolinones I [R1 = H, 7-Br, 10-NO2, etc.; R2 = CH2CH=CH2, Ph, 4-MeC6H4, etc.; R3 = H, Me; R4 = Me, Ph, 2-furyl] and chromenopyranoquinolinones II [R5 = H, 10-Me, 7-Br, etc.; R6 = H, 3-MeO, 2-Br, etc.] via iridium catalyzed reductive annulation of N-heteroarenium salts with formaldehyde and cyclic 1,3-diketones or 4-hydroxycoumarins, proceeding with broad substrate scope, good functional group compatibility, readily available feedstocks, and high step and atom efficiency was described.

Chemical Communications (Cambridge, United Kingdom) published new progress about Benzopyrans Role: RCT (Reactant), RACT (Reactant or Reagent). 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Product Details of C10H18O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Putra, T. W. published the artcileIntensification of biolubricant synthesis from waste cooking oil using tetrahydrofuran as co-solvent, Quality Control of 111-87-5, the main research area is intensification biolubricant synthesis waste cooking oil THF cosolvent.

In this study, biolubricant was synthesized through two stages of transesterification. The first transesterification was the reaction between waste cooking oil and ethanol using sodium hydroxide as catalyst to produce fatty acid Et esters (FAEE). The second transesterification was the reaction between FAEE and 1-octanol using potassium hydroxide as catalyst with THF as co-solvent to produce fatty acid octyl esters (biolubricant). This study was focused on the effect of THF as co-solvent in the second transesterification. Biolubricant yield of 94.42% was obtained at reaction conditions (temperature of 125°C, time of 180 min, reactant molar ratio of 1:4, catalyst amount of 1%-weight/weight, vacum pressure of 100 mmHg and co-solvent amount of 25%-weight/weight). The physicochem. properties of biolubricant were kinematic viscosities of 10.47 mm2/s and 2.75 mm2/s at 40°C and 100°C, viscosity index of 103 and acid number of 0.62 mg KOH/g.

IOP Conference Series: Materials Science and Engineering published new progress about Edible oils Role: RCT (Reactant), RACT (Reactant or Reagent). 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Quality Control of 111-87-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts