Category: alcohols-buliding-blocks

Taktak, Nehad E. M. published the artcileNanoemulsions containing some plant essential oils as promising formulations against Culex pipiens (L.) larvae and their biochemical studies, Computed Properties of 124-76-5, the main research area is Culex larva essential oils nanoemulsions formulations larvicidal; Biochemical studies; Culex pipiens; Essential oils; GC/MS; Larvicidal activity; Nanoemulsions.

The chem. composition of cypress, lavender, lemon eucalyptus, and tea tree oils has been investigated using gas chromatog./mass spectrometry (GC/MS). These oils were tested for larvicidal activity against Culex pipiens alongside their nanoemulsions (NEs) and conventional emulsifiable concentrates (ECs). Oil-in-water (O/W) NEs preparation was based on a high-energy ultra-sonication technique. The effect of independent variables of preparation on the different outputs was studied using the response surface method to obtain the optimum preparation technique. The droplet sizes of prepared NEs were significantly different (71.67, 104.55, 211.07, and 70.67 for cypress, lavender, lemon eucalyptus, and Tea tree NEs, resp.). The zeta potentials of NEs were recorded to have a high neg. charge (-28.4, -22.2, -23.6, and – 22.3 mV for cypress, lavender, lemon eucalyptus, and tea tree NEs, resp.). The results showed that the tea tree oil has the most significant effect with LC50 = 60.02 and 57.10 mg/L after 24 and 48 h of exposure, resp. In comparison, cypress oil proved the lowest toxicity with LC50 values of 202.24 and 180.70 mg/L after 24 and 48 h, resp. However, lavender oil does not show any effect against larvae at tested concentrations In addition, pure oil exhibited the lowest larvicidal activity. However, the EC of all tested insecticides slightly improved the toxic action against the larvae. While the NEs showed significantly high toxicity compared to the EO and EC. An in vivo assessment of acetylcholine esterase (AChE), ATPase (ATPase), and gamma-aminobutyric acid transaminase (GABA-T) revealed that the NEs exhibited higher activity than the pure oils and ECs. This work describes these oils with potential use against C. pipiens larvae as eco-friendly products.

Pesticide Biochemistry and Physiology published new progress about Corymbia citriodora. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Computed Properties of 124-76-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Bhattacharjee, Apurba K. published the artcileIn Silico Stereo-Electronic Analysis of PMD (p-Menthane-3-8-Diol) and its Derivatives for Pharmacophore Development May Aid Discovery of Novel Insect Repellents, Formula: C10H20O2, the main research area is menthanediol derivative electrostatic potential model insect repellent.

PMD (p-menthane-3-8-diol) is an insect repellent that can be synthesized chem. or derived from a steam distillate residue of the leaves of lemon eucalyptus, Corymbia citriodora. It is one of the few natural product endorsed by the Center for Disease Control (USA) for topical application to protect against mosquitoes though it is not as effective as the common repellent DEET (N,N-diethyl-1,3-toluamide). However, DEET has several undesirable side effects and toxicity too. Thus, although PMDs are comparatively safer than DEET, no quant. structure activity relationship (QSAR) and pharmacophore modeling studies have been reported in literature to improve efficacy and aid further development of more effective PMD analogs. In this study, we report results of quantum chem. anal. of stereoelectronic properties and pharmacophore modeling of PMD and eight of its synthetic derivatives to aid discovery and design of more effective PMD analogs. Stereo-electronic anal. indicates that lower aqueous stabilization (favorable lipophilicity) and larger separation of electrostatic potential energy together with a large localized neg. electrostatic potential region by the oxygen atom play important roles for repellent activity. Consistent to these properties, the generated pharmacophore model of the PMDs showed two aliphatic hydrophobic and a hydrogen-bond donor features for potent activity. These results aided us to design more effective PMD repellents which are currently under further investigations.

Current Computer-Aided Drug Design published new progress about Corymbia citriodora. 42822-86-6 belongs to class alcohols-buliding-blocks, name is 2-(2-Hydroxypropan-2-yl)-5-methylcyclohexanol, and the molecular formula is C10H20O2, Formula: C10H20O2.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kirton, L. G. published the artcileLaboratory and field tests of the effectiveness of the lemon-eucalyptus extract, citriodiol, as a repellent against land leeches of the genus Haemadipsa (Haemadipsidae), Application of 2-(2-Hydroxypropan-2-yl)-5-methylcyclohexanol, the main research area is citriodiol Corymbia citriodora extract land leech repellent.

Citridiol is an extract of the leaves of Corymbia citriodora (Myrtaceae), the lemon eucalyptus, and mostly consists of p-menthane-3,8-diol isomers. The effectiveness of this extract as a repellent against land leeches of the genus Haemadipsa (Haemadipsidae), primarily H. sylvestris, was tested in the laboratory and field, in Peninsular Malaysia. The formulation tested, Mosi-guard Natural spray, contained 40% (weight/weight) citriodiol in a base of EtOH, water, and isopropanol. In the laboratory test, specimens of H. sylvestris that were placed within moist, untreated arenas enclosed by treated paper rings made numerous attempts to cross the rings but were prevented or delayed from crossing over, in a dose-dependent manner. Mortality was high among the leeches that attempted to cross over the paper rings that had been sprayed to saturation point but low among the leeches that attempted to cross over paper rings that had only been partially treated, with a droplet-spray. The field study was carried out using indexes that were formulated to reflect the severity of leech attack and the degree of repellency. Heavy or moderate spraying of footwear and trouser legs (tucked into socks) not only gave complete protection against bites by H. sylvestris and H. picta but also provided high enough repellency to keep the treated footwear virtually free of leeches. Even a light spray greatly reduced the numbers of leeches on footwear and delayed their progression toward biting the test subjects, although it failed to prevent bites completely. There was no decline in the repellency of the citriodiol when hourly assessments were made over a 6-h test period in the field. The results of the study show that citriodiol is highly repellent as well as toxic to leeches, and can be effectively used to prevent leech bites in the field.

Annals of Tropical Medicine & Parasitology published new progress about Corymbia citriodora. 42822-86-6 belongs to class alcohols-buliding-blocks, name is 2-(2-Hydroxypropan-2-yl)-5-methylcyclohexanol, and the molecular formula is C10H20O2, Application of 2-(2-Hydroxypropan-2-yl)-5-methylcyclohexanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhang, Li published the artcileEffects of the chain length of crosslinking agent and dye-doped amount on the electro-optical properties of polymer-dispersed liquid crystal films prepared by nucleophile-initiated thiol-ene click reaction, Safety of Pentaerythritol tetra(3-mercaptopropionate), the main research area is crosslinking dye doped electrooptical property polymer dispersed liquid crystal.

A series of crosslinking agents with different chain lengths were used to explore their effect on electro-optical properties of dye-doped polymer dispersed liquid crystals (PDLCs) film prepared by nucleophile-initiated thiol-ene click reaction. The influences of dye contents and temperatures on electro-optical properties were also investigated. It was found that the increase in chain length of crosslinking agent leads to the increase in driving voltage and the decrease in memory effect. The decrease in reaction temperature causes a decrease in driving voltage and an increase in transmittance. Particularly, the dye content could be optimized to obtain promising materials with min. driving voltage and high contrast ratio for display applications.

Liquid Crystals published new progress about Crosslinking agents. 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, Safety of Pentaerythritol tetra(3-mercaptopropionate).

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Jego, Lucas published the artcileStudy of the Photocrosslinking of Ethylene Propylene Diene Monomer Terpolymer Under UV Irradiation, Quality Control of 7575-23-7, the main research area is ethylene propylene diene monomer terpolymer photocrosslinking UV Irradiation.

The photocrosslinking of thick samples of 5-ethylidene-2-norbornene-ethylene propylene diene monomer (ENB-EPDM) under air at room temperature was investigated. First, a model study was carried out on low-mol. weight oligomers: squalene, 1,2-polybutadiene, and 1,4-polybutadiene. Several crosslinking agents (meth(acrylics), bismaleimide, and thiol) combined with various photoinitiators were tested to improve the reactivity of these oligomers under UV irradiation Gel contents, crosslinking densities, viscosities, and viscoelastic properties were measured in order to characterize the extent of crosslinking. Acrylate-based crosslinking agents appeared to be the most reactive species and these results were then applied to a low-mol. weight EPDM. Several photoinitiators were tested and benzophenone turned out to be the most efficient photoinitiator when combined with trimethylolpropane triacrylate. Finally, a com. EPDM was subsequently photocrosslinked and high gel content and crosslinking d. were obtained after only 2 min of irradiation

Polymer Engineering & Science published new progress about Crosslinking agents. 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, Quality Control of 7575-23-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chen, Huan published the artcileFluorochromic polymeric elastomer film containing copper nanoclusters in response to multistimuli, Formula: C17H28O8S4, the main research area is fluorochromic acrylic elastomeric film copper nanocluster smart material.

Smart chromic elastomers exhibiting multistimuli responsiveness are of interest with regard to the development of sensors, optical data storage, and smart wearable devices. We report a new design of Cu nanoclusters (Cu NCs) containing polymeric elastomer film, showing reversible fluorescence ON/OFF when subjected to organic solvents (e.g. ethanol, methanol and tetrahydrofuran), and heating/cooling cycles at temperatures lower than 80°. Different from the solvato-responsiveness of Cu NCs in solution state, organic solvents increase nonradiative decay and quench fluorescence emission in the solid polymer matrix. It is deduced that lower temperatures (80°) trigger an irreversible change of the aggregation state of Cu NCs in the elastomer film. A strong oxidizer (e.g. H2O2) irreversibly quenches the fluorescence emission and changes its color (under sunlight) from light green to blue, by oxidizing Cu NCs to Cu2+ ions. This Cu NC-containing elastomer film illustrates a new pathway to the fabrication of multi-responsive smart optical materials, particularly for potential applications in optical data storage (e.g. thermo-printing), and multistimuli-responsive elastomeric sensors integrated into wearable devices.

Nanotechnology published new progress about Crosslinking agents. 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, Formula: C17H28O8S4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wagner, Maximilian published the artcileMultiresponsive Polymer Nanoparticles Based on Disulfide Bonds, Synthetic Route of 7575-23-7, the main research area is multiresponsive polymer nanoparticle disulfide bond.

A disulfide polymer that is triggerable by ultrasound, UV, and redox in aqueous solution and can self-assemble with ionic probe mols. into again multitriggerable assemblies is presented. It is created by oxidative coupling of a branched insoluble thiol to water-soluble ionic thiols. The synthesis via a nanopptn. technique results in charged macromol. particles with adjustable sizes between a few tens and a few hundred nanometers stable in aqueous solution Macromols. of different compositions form with pentaerythritol tetrakis(3-mercaptopropionate) as insoluble crosslinkers yielding the polymer backbone, while mercaptopropionic acid, mercaptosuccinic acid, or aminoethane thiol in varying amounts is coupled to the backbone. Mol. and nanoscale switchability of the disulfide macromol. with UV light, redox potential, and ultrasound is demonstrated. The anionic character of the polymer particles is exploited by electrostatic self-assembly with the tetra-cationic 5,10,15,20-tetrakis-(N-methyl-4-pyridyl)porphyrin and its zinc-metalated derivative, yielding supramol. composite structures as a model system for delivery. The new type of polymer particles in aqueous solution may pave an alternative way toward multiresponsive and functional materials with potential in medicine and material science.

Macromolecules (Washington, DC, United States) published new progress about Crosslinking agents. 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, Synthetic Route of 7575-23-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhu, Minqian published the artcileStructural characterization and immunological activity of pectin polysaccharide from kiwano (Cucumis metuliferus) peels, Application In Synthesis of 59-23-4, the main research area is Cucumis peel macrophage immunol pectin polysaccharide; Immunological activity; Kiwano (Cucumis metuliferus) peels; Pectin polysaccharide; Structural characterization.

Two novel polysaccharides, namely CMPP-1 and CMPP-2, from kiwano (Cucumis metuliferus) peels were isolated through hot-water extraction, followed by ethanol precipitation and column chromatog. The results showed that CMPP-1 and CMPP-2 were hetero-galacturonans with different mol. weights of 7.35 kDa and 6.90 kDa, resp. Both of CMPP-1 and CMPP-2 were mainly composed of glucuronic acid (45.93% and 51.75%, resp.), and other monosaccharides including rhamnose, arabinose, galactose, glucose, xylose, fucose, mannose, galacturonic acid, and mannuronic acid. The results of structural characterization from FT-IR and NMR confirmed that CMPP-1 and CMPP-2 were pectin with highly branched structure. Furthermore, both CMPP-1 and CMPP-2 possessed immune-enhancing activity and could enhance the secretion of nitric oxide and cytokines (TNF-α, IL-6) in a dose-dependent manner. Especially, CMPP-1 had higher immune activity than CMPP-2 as the min. effective concentration were 0.78μg/mL and 6.25μg/mL, resp. These findings provide a scientific basis for further utilization of polysaccharide from kiwano peels.

Carbohydrate Polymers published new progress about Cucumis metuliferus. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Application In Synthesis of 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Verma, Ram Swaroop published the artcileEssential oil composition of the sub-aerial parts of eight species of Cymbopogon (Poaceae), Computed Properties of 124-76-5, the main research area is cymbopogon essential oil sub aerial pinane carane myrcane.

The genus Cymbopogon (Poaceae) comprised of many species of grasses that grow in tropical and subtropical regions around the world. Some of the com. important aromatic species of Cymbopogon are cultivated for the extraction of the essential oils from their aerial-parts. In spite of wide distribution and large scale cultivation, the essential oils of the sub-aerial parts (root/rhizome) of these species have not been systematically studied so far. In this study, the hydro-distilled essential oils from the sub-aerial parts of eight species, including a hybrid of Cymbopogon, namely C. flexuosus (Nees ex Steud.) W.Watson, C. khasianus (Hack.) Stapf ex Bor, C. pendulus Nees ex Steud., C. khasianus × C. pendulus, C. winterianus Jowitt ex Bor, C. martini (Roxb.) W.Watson, C. distans (Nees ex Steud.) W.Watson, and C. jwarancusa (Jones) Schult. and their varieties/chemotypes were analyzed by gas chromatog.-flame ionization detector (GC-FID) and gas chromatog.-mass spectrometry (GC-MS). A total of thirty-three terpene C-skeleton types (six monoterpene skeletons, twenty-seven sesquiterpene skeletons) were identified. A multivariate statistical comparison by principal component anal. and agglomerative hierarchical clustering grouped the examined essential oils in to four clusters (cluster I: geraniol, and piperitone/ geraniol chemotypes; cluster II: high elemol and low elemol chemotypes; cluster III: limonene chemotype; and cluster IV: 5-epl-7-epl-α-eudesmol/eudesmanediol/hinesol, and cis-p-menth-2-en-1-ol/trans-p-menth-2-en-1-ol/eudesmanediol chemotypes).

Industrial Crops and Products published new progress about Cymbopogon citratus. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Computed Properties of 124-76-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Lin, Derong published the artcileStudy on the functional properties and structural characteristics of soybean soluble polysaccharides by mixed bacteria fermentation and microwave treatment, HPLC of Formula: 59-23-4, the main research area is Neurospora soybean soluble polysaccharide fermentation microwave treatment; Functional properties; Soybean soluble polysaccharides; Structural characteristics.

The soybean soluble polysaccharide was prepared by mixed fermentation of lactic acid bacteria and Neurospora crassa and microwave treatment. The functional properties and structure characteristics of soybean soluble polysaccharide before and after modification were compared. Results revealed that after fermentation treatment, the content of soybean soluble polysaccharide increased to 7.09%, which was 3.16 times that of raw materials, and the microwave treatment was further increased to 7.69%. The glucose adsorption capacity, glucose dialysis retardation index and the α-amylase activity inhibition ration of soybean soluble polysaccharides increased significantly, promotes intestinal flora growth in vitro after fermentation of mixed bacteria and microwave treatment. At the same time, the anal. of monosaccharide compound and structural characteristics showed that the monosaccharide components of soybean soluble polysaccharide were redistributed after modification treatment, SEM showed that modified soybean soluble polysaccharide has a larger surface area; Fourier Transform IR spectroscopy and X-ray Diffraction proved that the modification has slight changes in the functional groups and crystal structure of soybean soluble polysaccharide. These results suggested that okara may be a potentially inexpensive source of natural soybean soluble polysaccharide and a potential functional food ingredient.

International Journal of Biological Macromolecules published new progress about Dehydration process. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, HPLC of Formula: 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts